MafB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific ... Transcription factor MafB also known as V-maf musculoaponeurotic fibrosarcoma oncogene homolog B is a protein that in humans is ... The gene-poor regions either side of the MAFB gene include numerous binding sites for transcription factors that are known to ... MAFB+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) MAFB human gene location in the ...

Here we show that mice deficient for the transcription factor MafB die from central apnea at birth and are defective for ... Here we show that mice deficient for the transcription factor MafB die from central apnea at birth and are defective for ... Transcription factors regulating the specification of brainstem respiratory neurons. Xia Y, Cui K, Alonso A, Lowenstein ED, ... Joint actions of diverse transcription factor families establish neuron-type identities and promote enhancer selectivity. ...

MAFB transcription factor network regulates epidermal differentiation. Dev Cell. 32(6): 693-706. ... Splicing and chromatin factors jointly regulate epidermal differentiation. Cell Rep, 25, 1292-1303.e5. ...

MAF bZIP transcription factor B. Gene namei Official gene symbol, which is typically a short form of the gene name, according ... The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the ... The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene ... Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid- ...

Crystal structure of the homodimeric MafB in complex with the T-MARE binding site ... we determined two high-resolution structures of the transcription factor MafB as a homodimer and as a heterodimer with c-Fos ... Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.. Pogenberg, V., Consani Textor, L. ... Our data provide a concept for transcription factor design to selectively activate dimer-specific pathways and binding ...

... microtubule-actin cross-linking factor 1; Maf1, transcription factor MafB; Mprip, myosin phosphatase Rho-interacting protein; ... Bayesian identification of candidate transcription factors for the regulation of Aqp2 gene expression. Kikuchi H, Jung HJ, ... transcription elongation factor A protein-1; Thrap3, thyroid hormone receptor-associated protein-3; Tpcn1, two-pore Ca2+ ... and CUL4-associated factor 8; Dstn, destrin; Erc1, ELKS/Rab6-interacting/CAST family member 1; Fam129b, niban-like protein-1; ...

2. Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB.. Smink JJ; Bégay V; Schoenmaker T; ... 4. Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone ... 1. Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.. Smink JJ; Tunn PU; ... 6. CCAAT/enhancer-binding protein β promotes receptor activator of nuclear factor-kappa-B ligand (RANKL) expression and ...

Mutations of brainstem transcription factors and central respiratory disorders. Blanchi, B.. Trends Mol Med, 2005 , 11, 23-30, ... Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate. Bakri, Y.. Blood, 2004 , 105, 2707-16, PMID: ... Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment. Sarrazin S., Sieweke M.. Semin ... MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages. Aziz A, Soucie E, Sarrazin S, Sieweke. ...

... and interacts with ETS-1 TRANSCRIPTION FACTOR.. Entry Term(s). MafB Proteins MafB Transcription Factors Registry Number. 0. ... Transcription Factors [D12.776.930] * Basic-Leucine Zipper Transcription Factors [D12.776.930.127] * Maf Transcription Factors ... Maf Transcription Factors [D12.776.260.108.500] * Maf Transcription Factors, Large [D12.776.260.108.500.061] * MafB ... Maf Transcription Factors, Large [D12.776.930.127.500.061] * MafB Transcription Factor [D12.776.930.127.500.061.500] ...

... and interacts with ETS-1 TRANSCRIPTION FACTOR.. Entry Term(s). MafB Proteins MafB Transcription Factors Registry Number. 0. ... Transcription Factors [D12.776.930] * Basic-Leucine Zipper Transcription Factors [D12.776.930.127] * Maf Transcription Factors ... Maf Transcription Factors [D12.776.260.108.500] * Maf Transcription Factors, Large [D12.776.260.108.500.061] * MafB ... Maf Transcription Factors, Large [D12.776.930.127.500.061] * MafB Transcription Factor [D12.776.930.127.500.061.500] ...

Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity. ... Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity. ... Here, we examined how hormone misexpression was influenced by the MAFA and MAFB transcription factors, closely related proteins ... Moreover, evidence is provided that human MAFB can directly repress GAST gene transcription. These results support a ...

MafB Transcription Factor Entry term(s). MafB Proteins MafB Transcription Factors Proteins, MafB Transcription Factor, MafB ... MafB Proteins. MafB Transcription Factors. Proteins, MafB. Transcription Factor, MafB. Transcription Factors, MafB. ... MafB Transcription Factor - Preferred Concept UI. M0479951. Scope note. A large maf protein that regulates HINDBRAIN ... and interacts with ETS-1 TRANSCRIPTION FACTOR.. Allowable Qualifiers:. AD administration & dosage. AE adverse effects. AG ...

1.1.3.1.3 MAFB. *. 1.1.3.1.4 NRL. *. 1.1.3.2 Small MAF ... 1.1 Basic leucine zipper factors (bZIP)*. 1.1.1 Jun-related. * ... Classification of Transcription Factors in Mammalia. About TFClass. Search in TFClass: ?. Searches in the label, ID and ...

The Maf proteins, including c-Maf, MafA, and MafB, are critical transcription factors in myelomagenesis. Previous studies ... The transcription factor PBX1 is regarded as an oncogene in various cancers, but its role in non-small cell lung cancer (NSCLC ... MafA and c-Maf are close members of the Maf transcription factor family and indicators of poor prognosis of multiple myeloma ( ... Factores de Transcripción Maf de Gran Tamaño/genética , Factor de Transcripción MafB/genética , Mieloma Múltiple/genética , ...

In addition, the influence of one transcription factor on the others was studied. After the expression of MafB in PECs a ... In dieser Arbeit wurden drei Transkriptionsfaktoren (Dach1, MafB und Foxc2) in PECs transfiziert. Für alle drei konnte in der ... It was studied whether one of these three factors could initiate a differentiation towards podocytes. ... MafB und Foxc2 in PECs. Allerdings konnte durch die Überexpression von Dach1 in PECs ein signifikanter Anstieg des Podozyten- ...

Large N0000169903 Maf Transcription Factors, Small N0000169859 MafB Transcription Factor N0000006329 Mafenide N0000178934 ... Factor Brn-3A N0000169848 Transcription Factor Brn-3B N0000169847 Transcription Factor Brn-3C N0000169876 Transcription Factor ... Factor DP1 N0000169840 Transcription Factor Pit-1 N0000169958 Transcription Factor RelA N0000169957 Transcription Factor RelB ... Factors N0000169973 E2F1 Transcription Factor N0000169969 E2F2 Transcription Factor N0000169970 E2F3 Transcription Factor ...

Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB. The EMBO Journal, 2009; DOI: 10.1038/emboj ... Factors that increase the likelihood of developing osteoporosis and fractures are called risk factors. These risk factors ... Alcohol intake as a risk factor for fracture. Osteoporos Int 2005;16:737-42.[CrossRef][Medline]. 4. Kanis JA, Johnell O, Oden A ... Women with a hip fracture are at a four-fold greater risk of a second one, and the risk factors are similar to those for the ...

TFE3 transcription factor regulates the expression of MAFB during macrophage differentiation 1-gen-2009 ZANOCCO MARANI, Tommaso ... TFE3 transcription factor regulates the expression of MAFB during macrophage differentiation. 2009 ZANOCCO MARANI, Tommaso; ... MafB is a downstream target of the IL-10/STAT3 signaling pathway, involved in the regulation of macrophage de-activation 1-gen- ... MafB is a downstream target of the IL-10/STAT3 signaling pathway, involved in the regulation of macrophage de-activation. ...

MAFB. 9935. MAFB. MAF bZIP transcription factor B [Source:.... MED6. 10001. MED6. mediator complex subunit 6 [Source:HGNC .... ... TFT: Transcription Factor Targets TFT:GTRD: GTRD TFT:TFT_LEGACY: TFT_Legacy C4: Computational CGN: Cancer Gene Neighborhoods CM ... In the present study we used Affymetrix oligonucleotide microarrays to produce gene transcription profiles for the major ...

Transcription Factors:. ADNP, AFF1, AFF2, AFF3, AFF4, ALX1, ALX3, ALX4, AP5Z1, ARID1A, ARID1B, ARID2, ARID5B, ARNT, ARNT2, ... MAFB, MAFF, MAFG, MAX, MEF2C, MEIS2, MEOX1, MESP2, MGA, MLXIPL, MNT, MNX1, MSGN1, MSX1, MSX2, MTF1, MXI1, MYB, MYBL1, MYCL, ...

Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity August 22, 2023 Jeeyeon ...

MafB Transcription Factor Mice Oncogene Proteins / physiology* Promoter Regions, Genetic Protein Binding Proto-Oncogene ... BACKGROUND:Members of the Maf family, including L-Maf, MafB and c-Maf, are "basic region/leucine zipper" (bZIP) transcription ... MafB and c-Maf regulate different sets of target genes by complex interactions with multiple factors that recognize cis- ... Recent studies reveal that L-Maf, c-Maf and MafB play key roles in vertebrate lens development.. RESULTS:We investigated the ...

... we used this system to overexpress the transcription factor Mafb from the endogenous locus. Expression of Mafb-targeting sgRNAs ... Upregulation of Mafb via this method also resulted in increased expression of the putative Mafb target genes. We also describe ... Next-generation sequencing technologies have vastly expanded our knowledge of factors that regulate the development and ... the Cas9-SAM complex activates gene transcription by recruiting endogenous transcriptional machinery to the targeted locus. To ...

... we searched for the transacting factors involved. The transcription factor MafB, which is encoded in zebrafish by mafba, is ... We found two motifs similar to the consensus MafB recognition element (MARE), termed MafB-1 and MafB-2 (Fig. 7A,B). The MafB-1 ... Fibroblast growth factor (FGF) signalling plays a major role, notably by controlling the expression of the transcription factor ... The bracket indicates MafB-probe shift complexes, which are abolished or largely abolished by mutation of the MafB-2 and MafB-1 ...

... green-labeled probe hybridizing to the IGH gene region at 14q32.3 and an orange-labeled probe hybridizing proximal to the MAFB ... The recurrent t(14;20) results in ectopic expression of the basic leucine zipper transcription factor MAFB which has an ... Home Probes XL XL t(14;20) IGH/MAFB DF. XL t(14;20) IGH/MAFB DF. Translocation/Dual Fusion Probe. Order Number. D-5105-100-OG. ... XL t(14;20) IGH/MAFB DF consists of a green-labeled probe hybridizing to the IGH gene region at 14q32.3 and an orange-labeled ...

JASPAR is the largest open-access database of curated and non-redundant transcription factor (TF) binding profiles from six ... JASPAR is an open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position ... Mafb. Rattus norvegicus Maf-related factors. Basic leucine zipper factors (bZIP). MA0117.2. MA0117. 2. Mafb. Mus musculus Maf- ...

UBE2O was found to interact with c-Maf, a critical transcription factor in MM, by the affinity purification/tandem mass ... and MafB belong to the large Maf subfamily because these transcription factors contain the complete structure and functional ... c-Maf is a frequently expressed basic leucine zipper transcription factors in MM. As a transcription factor, c-Maf binds to the ... In addition, c-Maf is a basic zipper family transcription factor and this class of transcription factors displays various ...

Here, we use single cell rna sequencing of isolated mouse neurons expressing the transcription factor pitx3, a marker for mda ... and mafb. Motor med høy ytelse og lang levetid for utmerket pålitelighet. Vi anbefaler at du bruker mindre enn 5 m av kabelen. ... in myeloid hematopoietic precursor cells decreases osteoclast formation by altering expression of the transcription factors c- ...

The metanephros originates from the intermediate mesoderm, which expresses odd-skipped related transcription factor 1 (Osr1). ... MAFB)-BFP2 glomerular organoids grown in 96-well plates. Additionally, the expression of the apoptosis marker caspase-3 ... SRY-box transcription factor 9, and ureteric bud lineage markers such as Gata3, Pax2, keratin type II cytoskeletal 8 (Krt8), ... POU-homeodomain transcription factor Pou3f3+ Barren BRN1+ distal tubules. Transmission electron microscopy analyses of these ...

... each expressing a distinct set of transcription factors, including egr2 (krox20), mafb, Hnf1 and Hox genes, that underlie ... 6T), and the transcription factors scrt1a, scrt2 (Fig. 6T; Fig. 7C,E) and nhlh2 (Fig. 6T; Table S2.6). ... S6; Table S2.3), which may constitute a transcription factor code (Burrill et al., 1997; Gross et al., 2002; Müller et al., ... We also analysed transcription factor expression using an algorithm to predict gene regulatory networks. We focussed on Scrt ...