Luo, M.; Fadeev, E.A.; Groves, J.T. Mycobactin-mediated iron acquisition within macrophages. Nat. Chem. Biol. 2005, 1, 149-153 ... De Monye, C.; Karcher, D.S.; Boelaert, J.R.; Gordeuk, V.R. Bone marrow macrophage iron grade and survival of HIV-seropositive ... To gain insight on the uptake by macrophages and cellular distribution of the set of rhodamine labelled chelators under study ... Neyrolles, O.; Wolschendorf, F.; Mitra, A.; Niederweis, M. Mycobacteria, metals, and the macrophage. Immunol. Rev. 2015, 264, ...

... such as Raw macrophages or THP-1-derived macrophages, as well as in primary mouse macrophages (bone marrow-derived macrophages ... Macrophages activated by PAMPs and IFN-γ, known as classically activated or M1 macrophages, secrete TNF-α and IL-1β and direct ... Treatment of macrophages with DHA or EPA induces major changes in gene expression in THP-1-derived, LPS-activated macrophages [ ... 2. Effects of Omega-3 Fatty Acids on Macrophage Function. Macrophages have a fundamental role as part of the innate immune ...

... and macrophages. Histopathology revealed clear age-dependent differences, with young hamsters launching earlier and stronger ... D) Immune cell influx score taking into account the infiltration of lung tissue with (i) neutrophils; (ii) macrophages; (iii) ... D) Immune cell influx score taking into account the infiltration of lung tissue with (i) neutrophils; (ii) macrophages; (iii) ... as well as macrophages in both groups, again with clear age-dependent differences over time (Figure 2F, Figures S2D and S3). ...

7 macrophages. Int. J. Mol. Sci. 2016, 17, 1199. [Google Scholar] [CrossRef][Green Version] ... These stimulating agents can be differentiated into macrophages, which are subsequently attracted to injured tissue sites by ...

... macrophages phagocytose the liposome-encapsulated drug; resulting in cytoplasmic drug release and rapid induction of macrophage ... Figure 2. Anti-tumor effects of innate immune cells: Both tumor-associated macrophages and neutrophils can be polarized to a ... Figure 2. Anti-tumor effects of innate immune cells: Both tumor-associated macrophages and neutrophils can be polarized to a ... Monocytes, macrophages, DCs. -. Engages TRAIL receptors 1 and 2 on tumor cells to induce apoptosis via both extrinsic and ...

Interests: extracellular vesicles; cancer immunology and immunotherapy; biology of monocytes and macrophages; myeloid derived ...

At the top is the annotation of eosinophil numbers (EOS) and macrophage numbers (Macs) in each sample. Note that, (1) the ... At the top is the annotation of eosinophil numbers (EOS) and macrophage numbers (Macs) in each sample. Note that, (1) the ... percentage of macrophages in BAL fluid; FeNO = fractional exhaled nitric oxide; ND = not determined. ...

1 or 10 µg/mL + baicalin (1, 10 µg/mL) and (+)-catechin (1, 10 µg/mL) in macrophages of RAW267.4 mouse. Reduction of macrophage ... The research has shown that the treatment with BCP reduces interferon-γ (IFN-γ) production, the main activator of macrophages, ... An in vitro study on macrophages of RAW267.4 [83] mice has revealed that BCP, administered in association to other two natural ... In the case of central nervous system pathologies, Iba-1, analogous protein of Aif-1, present only in macrophages and microglia ...

... which mediates macrophages and NK-cell activity. Increased macrophage activity leads to increased cytokine levels (IL-6, TNF-α ... which mediates macrophages and NK-cell activity. Increased macrophage activity leads to increased cytokine levels (IL-6, TNF-α ... Both IFN-regulating factors and NF-κB are stimulated by macrophages [65]. IFNs are also potent somnogenic substances like IL-1 ... and macrophage inhibitory protein 1β [76,77]. IL-1 has been reported to release serotonin and NA in the hypothalamus [78]. This ...

Granulocyte-macrophage colony-stimulating factor. −10.16. Ereg. Proepiregulin. −2.44. Rgs9. Regulator of G-protein signaling 9 ... However, recent studies convincingly demonstrate that a cascade of inflammatory events, such as lymphocyte and macrophage ...

Sheu, F.; Lai, H.-H.; Yen, G.-C. Suppression effect of soy isoflavones on nitric oxide production in raw 264.7 macrophages. J. ... and to inhibit the overproduction of NO and PGE2 induced by LPS plus IFN-γ in RAW 264.7 macrophages by transcriptomic profiling ... Macrophages are the major cells releasing pro-inflammatory cytokines. Isoflavone pretreatment has been shown to regulate gene ... iNOS is induced by bacterial LPS and/or pro-inflammatory cytokines to overproduce NO in macrophages and other cells [102,103]. ...

Petrie, T.A.; Strand, N.S.; Yang, C.T.; Rabinowitz, J.S.; Moon, R.T. Macrophages modulate adult zebrafish tail fin regeneration ... Godwin, J.W.; Pinto, A.R.; Rosenthal, N.A. Macrophages are required for adult salamander limb regeneration. Proc. Natl. Acad. ... Munoz-Canoves, P.; Serrano, A.L. Macrophages decide between regeneration and fibrosis in muscle. Trends Endocrinol. Metab. 2015 ... The wound epithelium, nerve supply and macrophages are critical components of the regenerating niche, without which ...

... stimulated RAW 264.7 macrophages. The T. lutea F&M-M36 methanolic extract contained 4.7 mg of FX and 6.22 mg of gallic acid ... stimulated RAW 264.7 macrophages. The T. lutea F&M-M36 methanolic extract contained 4.7 mg of FX and [...] Read more. ... and inhibition of LPS-induced NO production in RAW264.7 macrophages. The results indicated that compounds 1, 2, and 4-6 ...

Immunomodulatory Effects of N-Acetyl Chitooligosaccharides on RAW264.7 Macrophages by Jun-Jin Deng ... PEA can be hydrolyzed by a lysosomal enzyme N-acylethanolamine acid amidase (NAAA), which is highly expressed in macrophages ... PEA can be hydrolyzed by a lysosomal enzyme N-acylethanolamine acid amidase (NAAA), which is highly expressed in macrophages ... In our previous study, LMWCs were found to elicit a strong immunomodulatory response in macrophages dependent on [...] Read ...

These activated macrophages induce the synthesis of angiogenic factors such as TNF-α, IL-6, IL-8, or NO, contributing to ... Leptin action in macrophages of the steatotic liver, through induction of iNOS and NADPH oxidase, causes peroxynitrite-mediated ... MacMicking, J.; Xie, Q.-W.; Nathan, C. NITRIC OXIDE AND MACROPHAGE FUNCTION. Annu. Rev. Immunol. 1997, 15, 323-350. [Google ... The increased sensitivity of ob/ob mice to proinflammatory and monocyte/macrophage-activating stimuli suggests a role for ...

Simons, J.W.; Sacks, N. Granulocyte-macrophage colony-stimulating factor-transduced allogeneic cancer cellular immunotherapy: ... tumor-associated macrophages (TAMs) and natural killer (NK) cells), cytokines (γ-IFN, IL6, IL10 and TGF-β) and other soluble ... PAP plus granulocyte-macrophage colony-stimulating factor (GM-CSF)), so far remains the only approved vaccine for asymptomatic ... tumor-associated macrophages (TAMs), natural killer (NK) cells and Treg cells), cytokines (e.g., interferon (IFN), interleukin ...

Brüne, B.; Courtial, N.; Dehne, N.; Syed, S.N.; Weigert, A. Macrophage NOS2 in Tumour Leukocytes. Antioxid. Redox Signal. 2017 ... The Presence of Cyclooxygenase 2, Tumour-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive ... enhanced presence of activated macrophages, lymphocytes and other inflammatory cells) was also detected together with ... numerous SOD1-immunopositive activated macrophages were detected particularly evident in collapsed areas, appearing heavily ...

... by macrophages [56,57], induces maturation of dendritic cells [58], increases T-cell proliferation and activation [59,60], and ... Effect of bone morphogenetic protein-6 on macrophages. Immunology 2009, 128, e442-e450. [Google Scholar] [CrossRef] [PubMed] ... Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction. Mol. Immunol. ... and to stimulate chemotactic responses in monocytes/macrophages [54,55], which play a central role in RA. ...

B) Nanoparticles that are not designed properly can be eliminated by the macrophages after opsonization process. (C) ... B) Nanoparticles that are not designed properly can be eliminated by the macrophages after opsonization process. (C) ... A strategy to avoid phagocytosis by macrophages is to functionalize the nanoparticle with the biocompatible and non-immunogenic ... Opsonin proteins from plasma typically can cover the nanoparticles, inducing the macrophages to recognize and eliminate the ...

... phenotypically consistent with macrophages. Macrophages represent the largest leucocyte populations in testis and epididymis [ ... Wang, Y.F.; Holstein, A.F. Intraepithelial lymphocytes and macrophages in the human epididymis. Cell Tissue Res. 1983, 233, 517 ... 34] postulated that PRRSV entered boar semen through replication in reproductive tissue macrophages that became infected upon ... a macrophage-specific protein, and recently it was postulated that these cells belong to the MPS, using RNA sequencing [33]. ...

Gliem, M.; Krammes, K.; Liaw, L.; van Rooijen, N.; Hartung, H.P.; Jander, S. Macrophage-derived osteopontin induces reactive ... RAW 264.7, murine leukemia macrophage cell line lysate; rat liver, rat liver whole cell lysate; A431 cell lysate, epidermoid ... RAW 264.7, murine leukemia macrophage cell line lysate; rat liver, rat liver whole cell lysate; A431 cell lysate, epidermoid ... After cerebral ischemia, OPN induces macrophage migration/activation and matrix remodeling, which provides new matrix-cell ...

There were moderate macrophage and foreign-body giant cell reactions without any necrosis or dystrophy in surrounding tissues. ... A histological semi-quantitative scoring system for the evaluation of macrophage and foreign-body giant cell reaction to the ... with macrophages (MPH) and giant cells (GC), while the outer layer (OL) consisted of a more mature connective tissue; IL grew ... with macrophages (MPH) and giant cells (GC), while the outer layer (OL) consisted of a more mature connective tissue; IL grew ...

Mercurio, A.; Schwarting, G.; Robbins, P. Glycolipids of the mouse peritoneal macrophage. Alterations in amount and surface ... macrophages and activated T cells [129-132], while the NK1.1 antigen is not expressed on all NK cells, and can also be found on ... X-linkage of the early in vitro alpha/beta interferon response of mouse peritoneal macrophages to herpes simplex virus type 2. ... Reactivity of anti-asialo GM1 serum with tumoricidal and non-tumoricidal mouse macrophages. J Leukoc Biol 1985, 37, 597-614. [ ...

Macrophage-Derived Adenosine Deaminase 2 Correlates with M2 Macrophage Phenotype in Triple Negative Breast Cancer ... Catecholamines Contribute to the Neovascularization of Lung Cancer via Tumor-Associated Macrophages. Brain. Behav. Immun. 2019 ... Ang-2/VEGF Bispecific Antibody Reprograms Macrophages and Resident Microglia to Anti-Tumor Phenotype and Prolongs Glioblastoma ... macrophages, fibroblasts, neutrophils, adipocytes) [3,4,5,6,7]. During this process, the increased proliferation of ECs leads ...

β-glucans, another class of EPSs, can interact with Dectin-1 receptors on the surface of macrophages and activate them [24]. As ... EPSs may modulate the immune response by interacting with dendritic cells (DCs) and macrophages and enhancing the proliferation ... Dectin-1 is a major beta-glucan receptor on macrophages. J. Exp. Med. 2002, 196, 407-412. [Google Scholar] [CrossRef][Green ... macrophages, and neutrophils by reducing the secretion of the pro-inflammatory tumor necrosis factor α (TNF-α) cytokine and ...

and IL-6 in lung injury and activated macrophages in vitro [17]. β. -glucans were also used to investigate oxidative stress ... This triggers the expression of interferons and activates antiviral effectors such as NK cells and macrophages, and DNA ... and intracellular reactive oxygen species in lipopolysaccharide-induced macrophage cells. They compared a conventional extract ... They can also stimulate the activity of macrophages [35] and neutrophils, support NK cell activity, influence the production of ...

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles. EMBO J. 2017, 36, 3336-3355. [Google ... Macrophages orchestrate breast cancer early dissemination and metastasis. Nat. Commun. 2018, 9, 21. [Google Scholar] [CrossRef ... Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis. Cell Rep. 2016, 15 ... Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nat. Cell Biol. ...

Loan, T.T.; Do, L.T.; Yoo, H. Platinum Nanoparticles Induce Apoptosis on Raw 264.7 Macrophage Cells. J. Nanosci. Nanotechnol. ... Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles. Free Radic. Biol, Med. 2005, 38, ... granulocyte-macrophage colony-stimulating factor (GM-CSF), and monocyte chemoattractant protein 1 (MCP-1). All these findings ... Fibroblast cells L929 or macrophages RAW264 treated with PtNPs exhibited loss of cell viability and DNA damage, and PtNPs also ...

Lactate secreted by cervical cancer cells modulates macrophage phenotype. J. Leukoc. Biol. 2019, 105, 1041-1054. [Google ... in the increases of M2 macrophages [92] and MDSC that inhibit NK activity [93]. Not only lactate produced by tumor cells, but ... and tumor-associated macrophages (TAMs). These changes may impair or favor the neoplastic growth, producing cellular quiescence ... cell survival regulation and macrophage differentiation. Toxicol. Appl. Pharm. 2013, 273, 196-208. [Google Scholar] [CrossRef] ...

... on a macrophage cell line (RAW 264.7). The multimodal characteristics of the hybrid NPs are confirmed with confocal microscopy ... A total of 7000 murine macrophage cells were added into each well and let to adhere to the bottom of the wells overnight. The ... The improved biocompatibility of Rh-CQDs NPs with respect to Rh NPs was demonstrated in vitro on RAW264.7 macrophages with the ... We exposed RAW 264.7 macrophage cell line to different CQDs concentrations and followed the viability and proliferation of the ...