Lysosome-associated membrane glycoprotein - Wikipedia
Lysosome-associated membrane glycoproteins (LAMPs) are integral membrane proteins, specific to lysosomes, and whose exact ... Fukuda Minoru (November 1991). "Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking". J. ... Holness CL, da Silva RP, Fawcett J, Gordon S, Simmons DL (1993). "Macrosialin, a mouse macrophage-restricted glycoprotein, is a ... CD69 (also called gp110 or macrosialin) is a heavily glycosylated integral membrane protein whose structure consists of a mucin ...
Limited and selective transfer of plasma membrane glycoproteins to membrane of secondary lysosomes. | Journal of Cell Biology |...
... was used as a membrane marker to study the compositio ... membrane glycoproteins to membrane of secondary lysosomes. T ... T Haylett, L Thilo; Limited and selective transfer of plasma membrane glycoproteins to membrane of secondary lysosomes.. J Cell ... of plasma membrane-derived constituents in the membrane of secondary lysosomes. Secondary lysosomes were separated from ... of internalized membrane is recycled via a membrane pool of secondary lysosomes. ...
Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8 + T cells directed...
We hypothesized lysosome-associated membrane glycoprotein 1 (LAMP1, CD107a) to be a marker for fratricide in TCR transgenic CD8 ... Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed ... Lysosome-associated membrane protein 1 (LAMP1/CD107a) is a transmembrane protein and has shown to be a specific marker for ...
Human LAMP1/CD107a Alexa Fluor® 488-conjugated Antibody IC7985G: R&D Systems
... lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1 ... LAMP1 (Lysosome-associated membrane protein-1; also CD107a) is a 100‑130 kDa member of the LAMP family of glycoproteins. It is ... Mature human LAMP1 is a 389 amino acid (aa) type I transmembrane glycoprotein. It contains a 354 aa luminal/extracellular ... CD107 antigen-like family member A; CD107a antigen; CD107a; LAMP1; LAMP-1; LAMPA; LGP120; lysosomal-associated membrane protein ...
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A subpopulation of CD163-positive macrophages is classically activated in psoriasis - Fingerprint - Albert Einstein...
Structure of human Niemann-Pick C1 protein.
Membrane Glycoproteins. *Lysosomes. *Intracellular Signaling Peptides and Proteins. *Humans. *DNA, Complementary. *Cholesterol ... Niemann-Pick C1 protein (NPC1) is a late-endosomal membrane protein involved in trafficking of LDL-derived cholesterol, Niemann ...
Sarid, R.<...
A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the...
... the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular ... rather than in lysosomes, as found for h-lamp-2. Potential clinical relevance of autoantibodies to gp170/80-110 and gp130 was ... the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular ... When membrane protein fractions were prepared from PMNs and isolated human glomeruli, and immunoblotted with ANCA sera of NCGN ...
The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis<...
Lysosome-Associated Membrane Glycoproteins Medicine & Life Sciences 36% * Macrophages Medicine & Life Sciences 34% ... In addition to elevated surface Lamp1 (lysosome-associated membrane protein 1) expression, we also observed enhanced secretion ... In addition to elevated surface Lamp1 (lysosome-associated membrane protein 1) expression, we also observed enhanced secretion ... In addition to elevated surface Lamp1 (lysosome-associated membrane protein 1) expression, we also observed enhanced secretion ...
Pfam: Protein: LAMP1 CHICK (P05300)
Immune Genes Protect Cells from Ebola Virus and SARS-CoV-2 | The Scientist Magazine®
... the p41-bound cathepsins are unable to cleave off the viruss glycoprotein, stopping it from fusing with the membrane and thus ... Later, the virus is likely brought to lysosomes and destroyed (not pictured). In a cell where CD74 is not overexpressed (right ... One isoform in particular, p41, could keep CD74 knockout cells alive in the face of the virus with the Ebola glycoprotein. ... Electron microscopy showed that, in cells expressing p41, the glycoprotein remained trapped inside the endosomes that housed ...
Darius Ebrahimi-Fakhari, M.D. | Harvard Catalyst Profiles | Harvard Catalyst
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Frontiers | Precision N-Glycoproteomic Profiling of Murine Peritoneal Macrophages After Different Stimulations
These glycoproteins are widely involved in important biological processes, such as antigen presentation, cytokine production ... These glycoproteins are widely involved in important biological processes, such as antigen presentation, cytokine production ... Under the stimulation of the different pathogens, glycoproteins showed a dramatic change. We found that receptors in the Toll- ... Under the stimulation of the different pathogens, glycoproteins showed a dramatic change. We found that receptors in the Toll- ...
Citations - Cusabio
Mouse Lysosome-associated membrane glycoprotein 2(LAMP2) ELISA kit,CSB-EL012740MO. Betanin improves motor function and ... α-Hemolysin promotes uropathogenic E. coli persistence in Bladder epithelial cells Via abrogating bacteria-harboring lysosome ... Astaxanthin protected against the adverse effects induced by diesel exhaust particulate matter via improving membrane stability ...
Suzanne Pfeffer's Profile | Stanford Profiles
Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export. eLife Li, J., Pfeffer, S. R. ... MANNOSE 6-PHOSPHATE RECEPTORS AND THEIR ROLE IN TARGETING PROTEINS TO LYSOSOMES JOURNAL OF MEMBRANE BIOLOGY Pfeffer, S. R. 1988 ... Lysosomes are lined with a glycocalyx that protects the limiting membrane from the action of degradative enzymes. We tested the ... Export of LDL-derived cholesterol from lysosomes requires the cooperation of the integral membrane protein Niemann-Pick C1 ( ...
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Task 3: Sequence-based predictions - Bioinformatikpedia
The lysosome-associated membrane glycoprotein 1 has the following annotated signal peptide and transmembrane helices: Position ... Type 4-A and 4-B insertion is also known as multipass membrane insertion. These proteins have not one trans-membrane helix like ... The import through the outer membrane is conducted by the TOM complex and the following import through the inner membrane is ... For example the stroma, inner and outer membrane, the thylakoids membrane or the thylakoids lumen. ...
A mannose 6-phosphate-containing N-linked glycopeptide derived from lysosomal acid lipase is bound to MHC class II in B...
Lysosomes, Mannosephosphates, Membrane Glycoproteins, Molecular Sequence Data, Peptides, Protein Binding, Receptor, IGF Type 2 ...
CD68 antibody [CD68/G2] | ICB Inhibitor icbinhibitor.com
It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein ... This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. ... The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a ... It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. ...
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Endolyn-78 Glycoprotein (78 kDa) present in membranes of endosomes ophion lysosomes but relatively scarce in other membranes. ... 306 1. Both the left and right cricothyroid arteries tradimg the superior aspect of the membrane legaal usually do not pose a ... coli have ion channels in their membranes that open in response to mechanical changes. In many cases, the genetic manipulation ... 5952 4 7. In the presence of adhesive serum glycoproteins, however, the differences became much smaller. ...
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Lysosome-associated membrane glycoprotein 2-positive lysosomes traffic to the plasma cell membrane in WT but not in CTSB KO N2 ... Lysosome has been long understood as a vital digestive organelle. Increasing reports indicate that the lysosome also plays a ... Cathepsin B is active at both the neutral pH 7.2 of the cytosol and the acidic pH 4.6 within lysosomes. We evaluated the ... Lysosomes are known to mediate neurite outgrowth in neurons. However, the principal lysosomal molecule controlling that ...
PROSITE
In yeast it (gene PHO8) is found in lysosome-like vacuoles and in mammals, it is a glycoprotein attached to the membrane by a ...
Alterations in EGF-Endocytosis, Lysosomal Enzyme Transport and Maturation of Cathepsins in Juvenile Neuronal Ceroid...
C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes. Traffic. ... Steenhuis P, Froemming J, Reinheckel T, Storch S. Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein ... Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile ... Role of the Lysosomal Membrane Protein, CLN3, in the Regulation of Cathepsin D Activity. J Cell Biochem. 2017;118(11):3883-90. ...
The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to...
These CD38-containing vesicles, likely of endosomal origin, appear to be proximal to lysosomes but not co-localized with them. ... mobilization from lysosomes during CCK-induced Ca(2+) signaling. In agreement with an intracellular site for messenger ... Lysosomes, Membrane Glycoproteins, Mice, Mice, Knockout, NADP, Nucleotidyltransferases, Pancreas, Exocrine, Rats ... These CD38-containing vesicles, likely of endosomal origin, appear to be proximal to lysosomes but not co-localized with them. ...