Lymphoid enhancer-binding factor 1 - WikipediaLymphoid enhancer-binding factor 1 - Wikipedia

Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a ... Lymphoid enhancer-binding factor 1 has been shown to interact with: ALX4, AML-1, CTNNB1, EP300, MITF PIAS4, SMAD2, and SMAD3. ... "Entrez Gene: LEF1 lymphoid enhancer-binding factor 1". Erdfelder F, Hertweck M, Filipovich A, Uhrmacher S, Kreuzer KA (2010). " ... Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. ...
more infohttps://en.wikipedia.org/wiki/Lymphoid_enhancer-binding_factor_1

anti-LEF1 antibody [1C3.1D10]  | GeneTexanti-LEF1 antibody [1C3.1D10] | GeneTex

... lymphoid enhancer-binding factor 1) for WB. Anti-LEF1 mAb (GTX12033) is tested in Human samples. 100% Ab-Assurance. ... Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member ... of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play ... lymphoid enhancer-binding factor 1. Background. ... 1 mg/ml (Please refer to the vial label for the specific ...
more infohttp://www.genetex.com/LEF1-antibody-1C31D10-GTX12033.html

Lef1{Delta}N binds {beta}-catenin and increases osteoblast activity and trabecular bone massLef1{Delta}N binds {beta}-catenin and increases osteoblast activity and trabecular bone mass

Lymphoid enhancer binding factor (Lef) 1 is a Wnt-responsive transcription factor that associates with β-catenin. Lef1N lacks ... Lymphoid enhancer binding factor (Lef) 1 is a high mobility group protein best known as a Wnt-responsive transcription factor ... Lymphoid enhancer binding factor (Lef) 1 is a Wnt-responsive transcription factor that associates with β-catenin. Lef1N lacks ... Lef1{Delta}N binds {beta}-catenin and increases osteoblast activity and trabecular bone mass. J Biol Chem. 2011 Jan 26. [Epub ...
more infohttp://www.asbmr.org/publications/field/archive.aspx?cid=cb3a448b-2b31-4428-b118-f88deca037c5

MicroRNA‑6852 suppresses glioma A172 cell proliferation and invasion by targeting LEF1MicroRNA‑6852 suppresses glioma A172 cell proliferation and invasion by targeting LEF1

Additionally, the results indicated that lymphoid enhancer binding factor 1 (LEF1) was directly inhibited by miR‑6852 and LEF1 ... Diagnostic utility of lymphoid enhancer binding factor 1 immunohistochemistry in small B-cell lymphomas. Am J Clin Pathol. 147: ... Pećina-Šlaus N, Kafka A, Tomas D, Marković L, Okštajner PK, Sukser V and Krušlin B: Wnt signaling transcription factors TCF-1 ... 1 Lu B, Zhou Y, Su Z, Yan A and Ding P: Effect of CCL2 siRNA on proliferation and apoptosis in the U251 human glioma cell line ...
more infohttps://tessera.spandidos-publications.com/10.3892/etm.2019.7762/abstract

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. - Sheridan P. L.Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. - Sheridan P. L.

en] Lymphoid enhancer-binding factor 1 (LEF-1) is a regulatory high mobility group (HMG) protein that activates the T cell ... Lymphoid Enhancer-Binding Factor 1 ; Molecular Sequence Data ; Nucleosomes/metabolism ; Proto-Oncogene Protein c-ets-1 ; Proto- ... Individually or collectively, none of the three enhancer-binding proteins (LEF-1, Ets-1, and TFE-3) could activate ... en] Animals ; Base Sequence ; Binding Sites ; Cloning, Molecular ; DNA, Viral/metabolism ; DNA-Binding Proteins/metabolism ; ...
more infohttp://orbi.ulg.ac.be/handle/2268/135381

LEF-1: Diagnostic utility in distinguishing basaloid neoplasms of the salivary gland - OpenEmoryLEF-1: Diagnostic utility in distinguishing basaloid neoplasms of the salivary gland - OpenEmory

Background: Lymphoid enhancer binding factor 1 (LEF-1) has recently been reported as a potential immunohistochemical (IHC) ... LEF-1: Diagnostic utility in distinguishing basaloid neoplasms of the salivary gland. Alessandra Schmitt, Emory University ... Among resections, there was a higher percentage of LEF-1 positive PA (84%) and BCA (86%), and a higher percentage of LEF-1 ... We evaluated the utility of LEF-1 in fine needle aspiration (FNA) and resection specimens to distinguish pleomorphic adenoma ( ...
more infohttps://open.library.emory.edu/publications/emory:tkghh/

The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector...The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector...

Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of ... innate lymphoid cell. iNKT cell. invariant NKT cell. LEF. lymphoid enhancer factor. LK. Lin−cKit+. MFI. mean fluorescence ... The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector ... The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector ...
more infohttp://jem.rupress.org/content/early/2015/04/14/jem.20141849

core binding factor alpha
     Summary Report | CureHuntercore binding factor alpha Summary Report | CureHunter

... core binding factor plays a key role in several development pathways and in human disease; has been sequenced ... 01/23/2004 - "Lymphoid enhancer factor-1 links two hereditary leukemia syndromes through core-binding factor alpha regulation ... Transcription Factors: 20597*Core Binding Factors: 223*Core Binding Factor alpha Subunits: 18*core binding factor alpha: 16 ... 11/07/2000 - "Binding of CBFalpha/AML/PEBP2alpha (core binding factor alpha/acute myelogenous leukemia/polyoma enhancer binding ...
more infohttp://www.curehunter.com/public/keywordSummaryC406688-core-binding-factor-alpha.do

Lef1 - Lymphoid enhancer-binding factor 1 - Mus musculus (Mouse) - Lef1 gene & proteinLef1 - Lymphoid enhancer-binding factor 1 - Mus musculus (Mouse) - Lef1 gene & protein

Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIASG antagonizes both Wnt- ... Lymphoid enhancer-binding factor 1Add BLAST. 397. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... sp,P27782,LEF1_MOUSE Lymphoid enhancer-binding factor 1 OS=Mus musculus OX=10090 GN=Lef1 PE=1 SV=1 ... transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Source: MGI ,p>Inferred from Genetic ...
more infohttps://www.uniprot.org/uniprot/P27782

LEF1 (lymphoid enhancer binding factor 1) - KOMP (Knockout Mouse Project)LEF1 (lymphoid enhancer binding factor 1) - KOMP (Knockout Mouse Project)

OMIM: LYMPHOID ENHANCER-BINDING FACTOR 1; LEF1*Gene Ontology: Lef1 *Mouse Phenome DB: Lef1 *UCSC: Chr.3:131,110,471-131,223,334 ... lymphoid enhancer binding factor 1. Synonyms: Lef-1, lymphoid enhancer factor 1. Gene nomenclature, locus information, and GO, ... Vega: OTTMUSG20276 (Lef1, lymphoid enhancer binding factor 1)*CCDS: 17842, 17842.1, 71319, 71320* ... Question? Comments? For Mice, Cells, and germplasm please contact us at [email protected], US 1-888-KOMP-MICE or International ...
more infohttps://www.komp.org/geneinfo.php?MGI_Number=96770

Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: regulation of lymphoid enhancer-binding...Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: regulation of lymphoid enhancer-binding...

We have previously reported that in cell cultures, HBsAg up-regulated the expression of lymphoid enhancer-binding factor 1 (LEF ... In this study we aimed to study this effect of HBsAg on LEF-1 in the development of HCC. Expression of HBsAg, LEF-1 and its ... By real-time PCR, the expression levels of LEF-1 downstream effector genes cyclin D1 and c-myc were higher in peritumor cells ... However, a 38 kDa truncated isoform of LEF-1, rather than the 55 kDa wild-type LEF-1, was significantly elevated in the HBsAg ...
more infohttps://jeccr.biomedcentral.com/articles/10.1186/1756-9966-28-58

YUHSpace: miR-449a regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer...YUHSpace: miR-449a regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer...

... miR-449a regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer-binding ... In this study, we determined that the lymphoid enhancer-binding factor-1 (LEF-1) was expressed during the chondrogenesis of ... regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer-binding factor-1. ... regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer-binding factor-1 ...
more infohttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91873

Recombinant Human LEF1 protein (ab153337) | AbcamRecombinant Human LEF1 protein (ab153337) | Abcam

Lymphoid enhancer-binding factor 1. *T cell specific transcription factor 1 alpha ... Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent ... Proline-rich and acidic regions are implicated in the activation functions of RNA polymerase II transcription factors. ... Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin ...
more infohttps://www.abcam.com/recombinant-human-lef1-protein-ab153337.html

Lef1 - PrimePCR Assay and Template | Life Science | Bio-RadLef1 - PrimePCR Assay and Template | Life Science | Bio-Rad

Lymphoid enhancer-binding factor 1 Assay Type: EvaGreen Application: Gene Expression Unique Assay ID: dRnoEG5138374 Info: EG; ... Lymphoid enhancer-binding factor 1 Assay Type: Probe Application: Gene Expression Unique Assay ID: dRnoCPE5172726 Info: FAM; ... Lymphoid enhancer-binding factor 1 Assay Type: Probe Application: Gene Expression Unique Assay ID: dRnoCPE5172727 Info: HEX; ... Lymphoid enhancer-binding factor 1 Assay Type: Probe Assay Design: intron_spanning Application: Gene Expression Unique Assay ID ...
more infohttp://www.bio-rad.com/en-us/prime-pcr-assays/gene/lef1-rat

The milk-derived fusion peptide, ACFP, suppresses the growth of primary human ovarian cancer cells by regulating apoptotic gene...The milk-derived fusion peptide, ACFP, suppresses the growth of primary human ovarian cancer cells by regulating apoptotic gene...

Anti-viabilities of ACFP were assessed by WST-1 (water-soluble tetrazolium 1), and apoptosis was measured using a flow ... lymphoid enhancer-binding factor 1. 0.36. 0.35. NM_005595. MAPK3/ERK1. mitogen-activated protein kinase 3 ... Cells were subsequently cultured in DMEM containing 0.1 mg/L epidermal growth factor (EGF), 0.1 mg/L insulin-like growth factor ... Binding buffer (400 μL) was subsequently added to each tube and the cells were analyzed by flow cytometry (EPICSR XL-MCL, ...
more infohttps://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2281-6

CGP049090
     Summary Report | CureHunterCGP049090 Summary Report | CureHunter

... and lymphoid enhancer-binding factor 1 (LEF1) leading to transcriptional inactivation of LEF1 in colon carcinoma cell lines. " ... connective tissue growth factor, fibronectin) and collagen gel contraction were evaluated in endometrial and endometriotic ... 1. Neoplasms (Cancer) 04/01/2010 - "In vivo studies exhibited tumor inhibition of 69% with CGP049090 and 57% with PKF115-584 ... Networked: 3 relevant articles (0 outcomes, 1 trials/studies) Bio-Agent Context: Research Results. *Organic Chemicals: 58* ...
more infohttp://www.curehunter.com/public/keywordSummaryC538948-CGP049090.do

lef1 Summary [species: Xenopus laevis and  Xenopus tropicalis] - Xenbase Gene Catalog
	lef1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

Gene Name: lymphoid enhancer binding factor 1 Synonyms: xlef-1 , lef-1 , xlef1 Add Xenopus synonyms , Nomenclature history Gene ... NP_001082124,lymphoid enhancer binding factor 1 L homeolog [Xenopus laevis] ... NM_001088655,Xenopus laevis lymphoid enhancer binding factor 1 L homeolog (lef1.L), mRNA ... NM_001243834,Xenopus tropicalis lymphoid enhancer binding factor 1 (lef1), mRNA ...
more infohttp://www.xenbase.org/gene/showgene.do?method=display&geneId=485516

a) Immunoblot analysis of β-catenin, cyclin D1, cycli | Open-ia) Immunoblot analysis of β-catenin, cyclin D1, cycli | Open-i

... we show that this interaction plays a critical role in regulating beta-catenin/T Cell Factor/Lymphoid Enhancer Factor-1 (LEF) ... lacking the main LEF binding sequence) were used together with 50 ng of pRL-TK renilla luciferase construct in each sample as ... we show that this interaction plays a critical role in regulating beta-catenin/T Cell Factor/Lymphoid Enhancer Factor-1 (LEF) ... lacking the main LEF binding sequence) were used together with 50 ng of pRL-TK renilla luciferase construct in each sample as ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC2195782_JCB0011002.f1c&req=4

LEF1 (Human) Recombinant Protein (Q01) - (H00051176-Q01) - Products - AbnovaLEF1 (Human) Recombinant Protein (Q01) - (H00051176-Q01) - Products - Abnova

lymphoid enhancer-binding factor 1. *Omim ID:. *153245. *Gene Ontology:. *Hyperlink. *Gene Summary: ... It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer ... LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905) ( ...
more infohttp://www.abnova.com/products/products_detail.asp?catalog_id=H00051176-Q01

GO PEPTIDYL LYSINE MODIFICATIONGO PEPTIDYL LYSINE MODIFICATION

lymphoid enhancer-binding factor 1. 51200. 51200. CPA4. carboxypeptidase A4. 51230. 51230. PHF20. PHD finger protein 20. ... TFT: transcription factor targets C4: computational gene sets CGN: cancer gene neighborhoods CM: cancer modules C5: GO gene ...
more infohttp://software.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_LYSINE_MODIFICATION.html

LEF1 cDNA (ANA10358) | DNA/cDNA/RNALEF1 cDNA (ANA10358) | DNA/cDNA/RNA

Lymphoid enhancer-binding factor 1. Description of Target:. This gene encodes a transcription factor belonging to a family of ... thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may ... The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, ... Cos-1 cells. LEF1 Antibody (OAEG00132). Application: WB, IHC. Species: Human, Mouse. ...
more infohttps://www.avivasysbio.com/lef1-cdna-ana10358.html

Gene expression profiling of postnatal lung development in the marsupial gray short-tailed opossum ( Monodelphis domestica)...Gene expression profiling of postnatal lung development in the marsupial gray short-tailed opossum ( Monodelphis domestica)...

Lymphoid enhancer binding factor 1. LMOD3. Leiomodin 3. LRRN4. Leucine rich repeat neuronal 4 ... Functional categories included growth factors, extracellular matrix protein (ECMs), transcriptional factors and signalling ... Transcriptional factors, growth factors, ECM proteins and MMPs mediate the interactions and participate in regulatory feedback ... regulatory factors (signalling molecules and transcriptional factors). Rows represent genes and columns represent development ...
more infohttps://rd.springer.com/article/10.1186%2Fs12864-018-5102-2

KEGG PATHWAY: ko05210KEGG PATHWAY: ko05210

lymphoid enhancer-binding factor 1. K08731 baculoviral IAP repeat-containing protein 5. ... New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and ... such as transforming growth factor receptor II (TGF-RII) and BAX. Hereditary syndromes have germline mutations in specific ...
more infohttps://www.kegg.jp/dbget-bin/www_bget?ko05210

Overview of Projects - Ulm UniversityOverview of Projects - Ulm University

Dissecting of the function of the "Lymphoid enhancer-binding factor 1" (Lef1) in acute myeloid leukemia. C. Buske. ...
more infohttps://www.uni-ulm.de/einrichtungen/sfb-1074/research/projects/overview-of-projects/

Anti-LEF1 antibody [EP2030Y] (ab53293) | AbcamAnti-LEF1 antibody [EP2030Y] (ab53293) | Abcam

Lymphoid enhancer-binding factor 1 antibody. *T cell specific transcription factor 1 alpha antibody ... Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent ... Proline-rich and acidic regions are implicated in the activation functions of RNA polymerase II transcription factors. ... Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin ...
more infohttp://www.abcam.com/lef1-antibody-ep2030y-ab53293.html