NIH/UW entry on Familial Lipoprotein Lipase Deficiency Gene therapy for lipoprotein lipase deficiency Lipoprotein+lipase at the ... "Entrez Gene: LPL lipoprotein lipase". Wang H, Eckel RH (2009). "Lipoprotein lipase: from gene to obesity". Am J Physiol ... lipoprotein-dependent)) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and ... Zechner R (1997). "The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism". ...
Familial lipoprotein lipase deficiency is a group of rare genetic disorders in which a person lacks a protein needed to break ... Familial lipoprotein lipase deficiency is a group of rare genetic disorders in which a person lacks a protein needed to break ... Familial lipoprotein lipase deficiency is a group of rare genetic disorders in which a person lacks a protein needed to break ... Familial lipoprotein lipase deficiency is caused by a defective gene that is passed down through families. ...
Diabetes mellitus is associated with a reduction of lipoprotein lipase (LPL) activity and development of hypertriglyceridemia. ...
Now that cardiologists and other doctors are comfortable talking about PCSK9 inhibitors they can start preparing to add a new mouthful of a therapeutic target to their vocabulary: angiopoietin-like-3 (ANGPTL3). Two papers published in the New England Journal of Medicine by industry researchers provide a snapshot of promising but still early research on two new drugs that target…. Click here to continue reading…. ...
The effects of dietary fatty acids on lipoprotein lipase activity and gene expression ... The extent and duration of this postprandial response is regulated by lipoprotein lipase (LPL). It is also known that the fatty ...
Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency ... Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency ... Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency. ...
Assessment of Genetic Diversity and Distance of Lipoprotein Lipase Between Red Jungle Fowl and Domestic Chicken Breeds ... Assessment of Genetic Diversity and Distance of Lipoprotein Lipase Between Red Jungle Fowl and Domestic Chicken Breeds table, ... Assessment of Genetic Diversity and Distance of Lipoprotein Lipase Between Red Jungle Fowl and Domestic Chicken Breeds. Journal ...
... hydrolyzes triglycerides in plasma lipoproteins and enables uptake of lipolysis products for energy production or storage in ... the localization of LPL and its endothelial anchoring protein glycosylphosphatidylinositol-anchored high density lipoprotein- ... Background: Lipoprotein lipase (LPL) hydrolyzes triglycerides in plasma lipoproteins and enables uptake of lipolysis products ... Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency. Nyrén, Rakel; Chang, ...
Human adipose tissue lipoprotein lipase (LPL) is stimulated in vivo by an insulin-glucose infusion. However, previous work by ... Human adipose tissue lipoprotein lipase (LPL) is stimulated in vivo by an insulin-glucose infusion. However, previous work by ... Philip A Kern, Angela Mandic, Robert H Eckel; Regulation of Lipoprotein Lipase by Glucose in Primary Cultures of Isolated Human ... Regulation of Lipoprotein Lipase by Glucose in Primary Cultures of Isolated Human Adipocytes: Relevance to Hypertriglyceridemia ...
DoctorInternet Practice and Research for Lipoprotein Lipase Deficiency, Familial. ... Lipoprotein Lipase Deficiency, Familial. Below are pre-structured command-links into the MEDLINE database on various aspects of ... Lipoprotein Lipase Deficiency, Familial. For each retrieval, 50 citations will be automatically displayed; however, one can ...
"Lipoprotein Lipase" by people in this website by year, and whether "Lipoprotein Lipase" was a major or minor topic of these ... Lipoprotein abnormalities in compound heterozygous lipoprotein lipase deficiency after treatment with a low-fat diet and ... "Lipoprotein Lipase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Lipopolysaccharide regulation of lipoprotein lipase expression in murine macrophages. Infect Immun. 1995 Mar; 63(3):858-64. ...
Click here to view our range of Lipoprotein Lipase Antibodies. ... It can mediate interactions of lipoproteins with cell surfaces ... Lipoprotein Lipase (LPL) is a triglyceride hydrolyzing enzyme that has been widely studied. ... Lipoprotein Lipase (LPL) is a triglyceride hydrolyzing enzyme that has been widely studied. It can mediate interactions of ... lipoproteins with cell surfaces and receptors, and deficiency or low activity can lead to hypertriglyceridaemia (a risk factor ...
Soliternova I.B., Nikulcheva N.G. (1979) Activity of postheparin lipoprotein lipase from rabbit blood plasma . Voprosy ... Activity of postheparin lipoprotein lipase from rabbit blood plasma // Voprosy Meditsinskoi Khimii. - 1979. - V. 25. -N 2. - P ... Soliternova I.B. et al., Activity of postheparin lipoprotein lipase from rabbit blood plasma . Voprosy Meditsinskoi Khimii ... Soliternova, I. B., Nikulcheva, N. G. (1979). Activity of postheparin lipoprotein lipase from rabbit blood plasma . Voprosy ...
Development of Small Molecule Screening Assay for Modulation of Lipoprotein Lipase activity Using Hepatocyte Secretome.. Title ... Venkatesh Sahana; Sadana Prabodh; Lin Li, "Development of Small Molecule Screening Assay for Modulation of Lipoprotein Lipase ... Development of Small Molecule Screening Assay for Modulation of Lipoprotein Lipase activity Using Hepatocyte Secretome. ... Lipase, Lipoproteins, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh, Venkatesh Sahana ...
... and lipoprotein lipase activity were intermediate between pancreas-kidney transplant patients and healthy controls. The ... In pancreas-kidney transplant patients postprandial lipemia was lowest and lipoprotein lipase activity was highest (average 32 ... High-density lipoprotein (HDL) cholesterol averaged 1.98 (0.40) mmol/L in pancreas-kidney transplant patients, clearly higher ... can be readily explained by the low postprandial triglyceride levels resulting from a high activity of lipoprotein lipase. The ...
Lipoprotein lipase (LPL), the rate-limiting enzyme for hydrolysis of plasma lipoprotein triglycerides, is a normal constituent ... Molecular studies on primary lipoprotein lipase (LPL) deficiency. One base deletion (G916) in exon 5 of LPL gene causes no ... Molecular studies on primary lipoprotein lipase (LPL) deficiency. One base deletion (G916) in exon 5 of LPL gene causes no ... We have systematically investigated a genetic defect resulting in a primary lipoprotein lipase (LPL) deficiency in a proband TN ...
Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein ... Structure, function and role of lipoprotein lipase in lipoprotein metabolism[J]. Curr Opin Lipidol, 1994, 5(2):117-125. ... Lipoprotein lipase gene mutations and the risk of cardiovascular diseases in children with obesity[J]. 中国当代儿科杂志, 2010, 12(3): ... Lipoprotein lipase gene mutations and the risk of cardiovascular diseases in children with obesity[J]. CJCP, 2010, 12(3): 161- ...
However, further research is needed to assess whether there are causal mechanisms by which heterozygous lipoprotein lipase ... is the rate-determining step in clearing triglyceride-rich lipoproteins from the circulation. Mutations that damage the LPL ... Importance: The activity of lipoprotein lipase (LPL) is the rate-determining step in clearing triglyceride-rich lipoproteins ... Lipoprotein Lipase, Lipoproteins, Male, Middle Aged, Mutation, Odds Ratio, Triglycerides ...
Extreme diabetic lipaemia associated with a novel lipoprotein lipase gene mutation. A.G. Mclean, C.J. Petersons, Amanda Hooper ... Extreme diabetic lipaemia associated with a novel lipoprotein lipase gene mutation. / Mclean, A.G.; Petersons, C.J.; Hooper, ... Extreme diabetic lipaemia associated with a novel lipoprotein lipase gene mutation. In: Clinica Chimica Acta. 2009 ; Vol. 406, ... Extreme diabetic lipaemia associated with a novel lipoprotein lipase gene mutation. Clinica Chimica Acta. 2009;406(1-2):167-169 ...
Medison to market uniQures Glybera in Israel for treatment of lipoprotein lipase deficiency uniQure N.V., a leader in human ... uniQures gene therapy product for the treatment of lipoprotein lipase deficiency (LPLD), in Israel and the Palestinian ... as the first treatment for patients with a rare disease known as lysosomal acid lipase (LAL) deficiency. ... para la Protección contra Riesgos Sanitarios in Mexico for Kanuma as a treatment for patients with lysosomal acid lipase ...
Open the PDF for P vu II Restriction Fragment Length Polymorphism of Lipoprotein Lipase in Russians in another window ... Lipoprotein lipase gene DNA polymorphism Population study Russians Short Communication Hum Hered 1993;43:388-390 V.A. Stepanov ... View article titled, P vu II Restriction Fragment Length Polymorphism of Lipoprotein Lipase in Russians ... P vu II Restriction Fragment Length Polymorphism of Lipoprotein Lipase in Russians ...
Lipoprotein Lipase / metabolism * Liver / enzymology * Male * Oxygen Consumption / drug effects * Postprandial Period / ...
M. Inoue, C. Z. Wu, D. Q. Dou, Y. J. Chen, and Y. Ogihara, "Lipoprotein lipase activation by red Ginseng saponins in ... The newly synthesized TG and CE in the chylomicrons are hydrolyzed by lipoprotein lipase (LPL) to yield chylomicron remnant ... "A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein," The Journal ... "High-density lipoproteins protect endothelial cells from apoptosis induced by oxidized low-density lipoproteins," Protoplasma, ...
Carriers of p.E40K, a variant that abolishes ANGPTL4 ability to inhibit lipoprotein lipase, have lower odds of T2D (odds ratio ... is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient ... Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. ... The lipoprotein lipase (LPL) pathway has emerged as an attractive therapeutic target for reducing lipid levels and ...
Therefore, we have evaluated the association of the common variants in the lipoprotein lipase (LPL) (D9N, N291S, and S447X), ... Therefore, we have evaluated the association of the common variants in the lipoprotein lipase (LPL) (D9N, N291S, and S447X), ... Common variants in the lipoprotein lipase gene, but not those in the insulin receptor substrate-1, the beta3-adrenergic ... Conversely, the variants in the IRS-1, FABP2, and beta(3)-AR genes did not show any major influence on lipid and lipoprotein ...
N2 - Lipoprotein lipase (LPL) is found in adipose tissue and muscle, and is important for the uptake of triglyceride-rich ... AB - Lipoprotein lipase (LPL) is found in adipose tissue and muscle, and is important for the uptake of triglyceride-rich ... Lipoprotein lipase (LPL) is found in adipose tissue and muscle, and is important for the uptake of triglyceride-rich ... abstract = "Lipoprotein lipase (LPL) is found in adipose tissue and muscle, and is important for the uptake of triglyceride- ...
Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in ... Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in ... Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in ... title = "Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into ...
Placental lipoprotein lipase (LPL) gene expression in a placentotrophic lizard, Pseudemoia entrecasteauxii.. *Post by: CIPPS ... Placental lipoprotein lipase (LPL) gene expression in a placentotrophic lizard, Pseudemoia entrecasteauxii.. ... Placental lipoprotein lipase (LPL) gene expression in a placentotrophic lizard, Pseudemoia entrecasteauxii. ...
Eckel, RH (1987) Adipose tissue lipoprotein lipase. In Lipoprotein Lipase, pp. 79-132 [Borensztajn, J, editor]. Chicago, IL: ... A key for the conversion of high density lipoprotein2 into high density lipoprotein3 by hepatic lipase. Journal of Clinical ... Farese, RV, Yost, TJ & Eckel, RH (1991) Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal- ... Sadur, CN & Eckel, RH (1982) Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique. ...