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*  Estimation of affinities of ligands in mixtures via magnetic recovery of target-ligand complexes and chromatographic analyses:...
For a candidate ligand whose affinity is much greater than that of the reference ligand, the quantities of the reference ligand ... candidate ligand(s) in the absence of the reference ligand while the concentration of the reference ligand is preset at a value ... If the candidate ligand and the reference ligand in the PMFS bind to the same site(s) on the target, NFS is the same in Eq.(1) ... The relative affinity of the candidate ligand to the reference ligand is defined as Kx/KA. In Eq.(1) and Eq.(2), CR is the same ...
https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-11-44
*  Ligand (biochemistry) - Wikipedia
This article is about ligands in biochemistry. For ligands in inorganic chemistry, see Ligand. For other uses, see Ligand ( ... Bivalent ligand[edit]. Bivalent ligands consist of two drug-like molecules (pharmacophores or ligands) connected by an inert ... High-affinity ligand binding implies that a relatively low concentration of a ligand is adequate to maximally occupy a ligand- ... In the example shown to the left, ligand-binding curves are shown for two ligands with different binding affinities. Ligand ...
https://en.wikipedia.org/wiki/Ligand_binding
*  Addressin ligands definition | Drugs.com
Definition of addressin ligands. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and definitions ...
https://www.drugs.com/dict/addressin-ligands.html
*  Landis Ligands | Sigma-Aldrich
Landis Ligands. By: William Sommer and Daniel Weibel, Aldrich ChemFiles 2008, 8.2, 84. ... Two of the essential components for highly active and selective catalysts are the ligand and the metal. Professor Landis and co ... Utilizing this newly developed ligand, Thomas and coworkers synthesized a series of oxazolines and imidazoles.1 Reacting vinyl ... Professor Landis and coworkers developed a new family of ligands based on 2,5‑disubstituted phospholane addressing these issues ...
https://www.sigmaaldrich.com/technical-documents/articles/chemfiles/landis-ligands.html
*  4-1BB ligand - Wikipedia
4-1BB+Ligand at the US National Library of Medicine Medical Subject Headings (MeSH) ... 4-1BBL (4-1BB ligand) is found on APCs (antigen presenting cells) and binds to 4-1BB. ... Retrieved from "https://en.wikipedia.org/w/index.php?title=4-1BB_ligand&oldid=842807712" ...
https://en.wikipedia.org/wiki/4-1BB_ligand
*  Epidermal Growth Factor-like Ligands | SpringerLink
EGF like ligands; Growth Factors Epidermal growth factor (EGF-)-like family members bind to and activate EGF receptor tyrosine ... Harris RC, Chung E, Coffey RJ (2003) EGF receptor ligands. Exp Cell Res 284:2-13CrossRefPubMedGoogle Scholar ... Wu WK, Tse TT, Sung JJ, Li ZJ, Yu L, Cho CH (2009) Expression of ErbB receptors and their cognate ligands in gastric and colon ... Dong J, Wiley HS (2000) Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their ...
https://link.springer.com/referenceworkentry/10.1007/978-3-642-27841-9_1933-2
*  Chronic inflammation and endogenous ligands
... Guest edited by Atsushi Kumanogoh. A thematic series in Inflammation and ...
https://www.biomedcentral.com/collections/CIEL
*  Gastrointestinal Cytoprotection by PPAR Ligands
ligand, pioglitazone, in rats," Redox Report, vol. 7, no. 5, pp. 294-299, 2002. View at Publisher · View at Google Scholar ... ligand, provides protection from dextran sulfate sodium-induced colitis in mice in association with inhibition of the NF-κB- ... ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells," Cancer Science, vol. 94, no. 4, pp. ... ligand, inhibits aspirin-induced gastric mucosal injury in rats," Alimentary Pharmacology and Therapeutics, vol. 15, no. 6, pp ...
https://www.hindawi.com/journals/ppar/2010/108632/ref/
*  Gastrointestinal Cytoprotection by PPAR Ligands
Ligands. Yuji Naito, Tomohisa Takagi, and Toshikazu Yoshikawa Molecular Gastroenterology and Hepatology, Graduate School of ...
https://www.hindawi.com/journals/ppar/2010/108632/abs/
*  Ligand Field | SpringerLink
Twenty years ago Tanabe and Sugano published the first ligand field energy diagrarns which are applicable to dN electronic ... The present volume is an attempt to fill the gap by providing a reasonable nurober of complete and accurate ligand field energy ... Twenty years ago Tanabe and Sugano published the first ligand field energy diagrarns which are applicable to dN electronic ...
https://link.springer.com/book/10.1007/978-1-4757-1529-3
*  Non-Innocent Ligands Home
Synthesis and ligand-based reduction chemistry of boron difluoride complexes with redox-active formazanate ligands M.-C. Chang ... From the themed collection: Non-Innocent Ligands The article was first published on 23 Dec 2014. Chem. Commun., 2015,51, 1553- ... From the themed collection: Non-Innocent Ligands The article was first published on 22 Jul 2014. Chem. Commun., 2014,50, 14290- ... From the themed collection: Non-Innocent Ligands The article was first published on 27 May 2014. Chem. Commun., 2014,50, 11440- ...
http://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=cc&themeid=e7c6d674-9775-4bf2-85a5-749d696a40f3
*  ligand - Everything2.com
Therefore, iron-haem complexes are ligands in the biochemical sense for the globin; and the oxygen is a ligand in the chemical ... providing some of its ligands.. Haem molecules occupy four ligand positions around the central iron atom, in a plane. When ...
https://everything2.com/title/ligand
*  Cocaine receptor binding ligands | RTI
The invention relates to novel compounds which show highaffinity for cocaine receptors in the brain, particularly dopamineand serotonin transporter sites. The compounds may be used asimaging or pharmaceutical agents, in the diagnosis and treatment ofdrug addiction, depression, anorexia and neurodegenerativediseases.
https://www.rti.org/publication/cocaine-receptor-binding-ligands
*  Receptor Ligands
An easy-to-use directory for life science and biomedical research products. Find special deals on products, order catalogs and browse product lines from suppliers of reagents, antibodies, laboratory equipment, and more.
http://www.biosupplynet.com/cfdocs/products/prod_supp.cfm?prod_id=1245
*  Basic Phosphine Ligands | Sigma-Aldrich
The ligand chosen for the reaction has showed outstanding results in a variety of cross-coupling transformations. Utilizing P(t ... Since the late 1990s several research groups have shown the versatility and efficiency of trialkyl phosphine ligands for a ... of ligand and 1.5 mol% of Pd2(dba)3, the reaction produced the desired biaryls with good to excellent yields (Table 1). It is ... Fu and coworkers explored the Hiyama transformation using one of their most versatile ligands, P(t-Bu)2Me.3 The Hiyama coupling ...
https://www.sigmaaldrich.com/technical-documents/articles/chemfiles/basic-phosphine-ligands.html
*  Cocaine receptor binding ligands | RTI
A class of binding ligands for cocaine receptors and other receptors in the brain. Specifically, a novel family of compounds ... A class of binding ligands for cocaine receptors and other receptors in the brain. Specifically, a novel family of compounds ...
https://www.rti.org/publication/cocaine-receptor-binding-ligands-2
*  ligand/metal noninnocence | PNAS
Ligand "noninnocence" in coordination complexes vs. kinetic, mechanistic, and selectivity issues in electrochemical catalysis ...
http://www.pnas.org/keyword/ligandmetal-noninnocence
*  Ligand Field Theory
... An important aspect of simple Crystal Field Theory is the orientation of the d-orbital lobes with respect ... If you know the author of Ligand Field Theory, please help us out by filling out the form below and clicking Send. ... Note that the lobes point towards either the centres of the faces (where the ligands would sit for an octahedral complex) or ... You just viewed Ligand Field Theory. Please take a moment to rate this material. ...
https://www.merlot.org/merlot/viewMaterial.htm?id=76241
*  Ligand Binding
... Dr E. Buxbaum EB15 at le.ac.uk Mon Mar 2 13:22:52 EST 1998 *Previous message: Algal Biliproteins ... Louis Hom wrote: , , Basic question: , Is there an activation energy associated with ligand binding? Yes, there is, and it is ...
http://www.bio.net/bionet/mm/proteins/1998-March/006224.html
*  Ligand - Wikipedia
Ligand exchangeEdit. A ligand exchange (also ligand substitution) is a type of chemical reaction in which a ligand in a ... Trans-spanning ligandsEdit. Main article: Trans-spanning ligand. Trans-spanning ligands are bidentate ligands that can span ... Spectator ligandEdit. Main article: Spectator ligand. A spectator ligand is a tightly coordinating polydentate ligand that does ... Binucleating ligandEdit. Binucleating ligands bind two metals.[10] Usually binucleating ligands feature bridging ligands, such ...
https://en.m.wikipedia.org/wiki/Ligands
*  Supply of Chiral Ligands - Chemistry, The University of York
Dr James Firth, lead chemist on the project, said: "Our approach to the family of sparteine chiral ligands allows synthesis of ... Their route uses common feedstock chemicals to make these chiral ligands on an unprecedented scale, moving away from the ... Sparteine and the sparteine surrogate, developed in York in 2002, are chiral ligands with the potential to synthesise mirror- ... York chemists solve long-term supply issues of sparteine chiral ligands. Posted on 30 January 2018 ...
https://www.york.ac.uk/chemistry/news/deptnews/york-chemists-solve-supply-of-chiral-ligands/
*  Xconomy: Japan Approves Ligand Drug
... and Welfare gave its approval to Ligand partner GlaxoSmithKline's ... San Diego's Ligand Pharmaceuticals (NASDAQ: LGND) says Japan's ... San Diego's Ligand Pharmaceuticals (NASDAQ: ]) says Japan's Ministry of Health, Labor, ... Ligand says eltrombopag is the first oral treatment that stimulates the production of blood platelets, considered essential to ... Ministry of Health, Labor, and Welfare gave its approval to Ligand partner GlaxoSmithKline's (NYSE: GSK) application for ...
https://xconomy.com/san-diego/2010/11/02/japan-approves-ligand-drug/
*  Automated design of ligands to polypharmacological profiles. - PubMed - NCBI
Overall, 800 ligand-target predictions of prospectively designed ligands were tested experimentally, of which 75% were ... Automated design of ligands to polypharmacological profiles.. Besnard J1, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang ... a) Closed loop of automated ligand design algorithm by multi-objective evolutionary optimisation. (b) Multi-objective ... Here we describe a new approach for the automated design of ligands against profiles of multiple drug targets. The method is ...
https://www.ncbi.nlm.nih.gov/pubmed/23235874
*  Structure-based discovery of β2-adrenergic receptor ligands | PNAS
Ligand Efficacy.. In the functional assay, 5 of the 6 ligands behaved as inverse agonists (Fig. 5); the activity of the sixth ... The combination of potent new ligands that resemble known antagonists and structures dissimilar to previously explored ligands ... for kinase-like ligands, 0.9% for LGIC-like ligands, and an even smaller proportion that resembles biogenic molecules such as ... using ligand probe charges in an electrostatic potential calculated by DelPhi (13, 21, 22)], corrected for ligand desolvation ( ...
http://www.pnas.org/content/106/16/6843
*  Low-Coordinate P-Ligands | Baumgartner Research Group at YorkU
These chelating ligands form catalytically active complexes with Pd and Pt and can efficiently be utilized in the ... Only recently, have sp2-hybridized phosphorus compounds been utilized as ligands for transition metals in catalysis. The ... Even polysubstituted alkenes can be converted which is not possible using classical lambda3-sigma3-phosphane ligands. ... Our research is aimed at the synthesis on development of novel chelating ligands that exhibit low-coordinate trivalent ...
http://www.yorku.ca/tbaumgar/overview/ligands.html