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*  The impact of adverse life events and the serotonin transporter gene promoter polymorphism on the development of eating...
Adverse life events have been shown to predict weight fluctuations and dietary restraint, as well as eating disorders during adolescence or early adulthood. Since the s-allele carriers of the 5-HTT gene-linked polymorphic region (5-HTTLPR) are biologically more reactive to stress related stimuli, we aimed to explore whether the eating disturbances are predicted by environmental stressors and moderated by the 5-HTTLPR genotype. The sample was based on the younger cohort of the Estonian Children Personality, Behaviour and Health Study and included those participating in its second and third wave. The history of stressful life events was self-reported at age 15. Data on eating behaviour and attitudes, anxiety, impulsivity and depressiveness were collected at age 18. The effect of the adverse life events on binge eating and on drive for thinness was found to be moderated by the 5-HTTLPR. Adolescent girls who at ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:489701
*  Mental Disorder and Adverse Life Events in a Forensic Intellectual Disability Service - Kent Academic Repository
The study investigated the frequency of adverse life events and prevalence of MD recorded for clients with intellectual disabilities (ID) in a medium secure unit, using data from an electronic patient record (EPR) system. Prevalence of MD was calculated on the basis of ICD-10 diagnoses and a 38-item checklist was developed to investigate adverse/traumatic life events for sub-samples with and without MD. High rates of MD were reported overall, particularly of schizotypal and delusional disorders and disorders of personality. Adverse life events including abuse, bereavement and relationship difficulties had been documented by clinicians. The overall number of recorded events was significantly higher for clients diagnosed with a MD. Associations between MD and life events have been reported previously, but not in a forensic ID population. The study contributes ...
https://kar.kent.ac.uk/24351/
*  AB0643 The Ψ-Reuma Project: Role of Early and Recent Life Events on Systemic Sclerosis (SSC) Clinical Presentation and Course |...
Results Compared to a group of matched controls (n=110), a higher proportion of patients reported at least one Stressful Life Events (56.3% vs 34.5%, p,0.01). All early life events were more frequently reported by SSc patients, even though a significantly difference was obtained only for "loss of mother" and for "sexual abuse" (13.6% vs 5.4%, p,0.05 and 16.4% vs 8.2%, p,0.05, respectively). Patients displayed a worse quality of life and a higher pain perception (all the subscales of SF-36 and of BPI were significantly different between the two groups, p,0.01). SSc patients, with a significant clinical worsening (33.6%), reported more frequently the occurrence of severe recent life events compared to patients without a significant clinical worsening (54.0% vs 26.0% p,0.05).. ...
http://ard.bmj.com/content/73/Suppl_2/1018.1
*  Development and assessment of stressful life events subscales - A preliminary analysis<...
TY - JOUR. T1 - Development and assessment of stressful life events subscales - A preliminary analysis. AU - Buccheri,Teresa. AU - Musaad,Salma. AU - Bost,Kelly K.. AU - Fiese,Barbara H.. AU - the STRONG Kids Research Team. PY - 2018/1/15. Y1 - 2018/1/15. N2 - Background Stress affects people of all ages, genders, and cultures and is associated with physical and psychological complications. Stressful life events are an important research focus and a psychometrically valid measure could provide useful clinical information. The purpose of the study was to develop a reliable and valid measurement of stressful life events and to assess its reliability and validity using established measures of social support, stress, depression, anxiety and maternal and child health. Methods The authors used an adaptation from the Social Readjustment Rating Scale (SRRS) to describe the prevalence of life ...
https://experts.illinois.edu/en/publications/development-and-assessment-of-stressful-life-events-subscales-a-p
*  Adverse life events, area socioeconomic disadvantage, and psychopathology and resilience in young children: the importance of...
Few studies on resilience in young children model risk appropriately and test theory-led hypotheses about its moderation. This study addressed both issues. Our hypothesis was that for preschool children's emotional/ behavioral adjustment in the face of contextual risk protective factors should be lo... mehr Few studies on resilience in young children model risk appropriately and test theory-led hypotheses about its moderation. This study addressed both issues. Our hypothesis was that for preschool children's emotional/ behavioral adjustment in the face of contextual risk protective factors should be located in the cognitive domain. Data were from the first two sweeps of the UK's Millennium Cohort Study. The final study sample was 4,748 three-year-old children clustered in 1,549 Lower layer Super Output Areas in nine strata. Contextual risk was measured at both area (with the Index of Multiple Deprivation) and family (with proximal and distal adverse life events experienced) ...
https://www.ssoar.info/ssoar/handle/document/20308
*  Biological stress systems, adverse life events and the onset of chronic multisite musculoskeletal pain: a 6-year cohort study |...
Methods Subjects (n=2039) of the Netherlands Study of Depression and Anxiety, free from chronic multisite musculoskeletal pain at baseline, were identified using the Chronic Pain Grade Questionnaire and followed up for the onset of chronic multisite musculoskeletal pain over 6 years. Baseline assessment of biological stress systems comprised function of the hypothalamic-pituitary-adrenal axis (1-h cortisol awakening response, evening levels, postdexamethasone levels), the immune system (basal and lipopolysaccharide-stimulated inflammation) and the autonomic nervous system (heart rate, pre-ejection period, SD of the normal-to-normal interval, respiratory sinus arrhythmia). The number of recent adverse life events was assessed at baseline using the List of Threatening Events Questionnaire. ...
http://ard.bmj.com/content/75/5/847
*  Does depression generate negative life events?
This prospective study investigated whether major depressive disorder can cause negative life events. One hundred and thirteen normal college men have been followed biennially from age 26 until age 62. Fourteen major negative life events were assesse
http://www.biomedsearch.com/nih/Does-depression-generate-negative-life/9091595.html
*  Frontiers | Type and Timing of Negative Life Events Are Associated with Adolescent Depression | Psychiatry
Previous studies have demonstrated an association between negative life events (NLEs) in childhood and resilience/posttraumatic growth (PTG) with regard to the pathogenesis of major depressive disorder. We hypothesized that the type and timing of NLEs interact to influence mental health in the general youth population. Therefore, the present study aimed to examine the effects of NLE timing and intensity on current depressive symptoms, and to determine the direct and indirect effects of NLEs/resilience on PTG and depression among non-clinical adolescents. Data were collected from 1,038 high school students across seven high schools in Fukui, Japan, during their freshman and sophomore years (648 boys and 390 girls, mean age = 15.71, SD = 0.524). Respondents completed a set of questionnaires designed to evaluate the type and timing of NLEs, depressive and traumatic symptoms, and PTG. Cluster analysis was used to divide participants into three groups based on outcomes:
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00041/full
*  HKU Scholars Hub: The influence of life events on the subsequent course of psychotic illness. A prospective follow-up of the...
Fifty-nine psychotic patients with acute onset of illness, who had been interviewed about their experience of stressful life events before the episode, were followed up for an average of 42 months. Thirty patients (51%) had experienced a stressful life event in the 3 months immediately before onset (EV+), 29 had not (EV-). In patients with an RDC diagnosis of affective disorder or unspecified functional psychosis, the presence of stressful life events was associated subsequently with milder symptom severity, less time spent in hospital, more treatment for depressive symptoms and less for psychotic symptoms. In schizophrenia, differences were less apparent, but patients with event associated episodes had less need of anti-psychotic maintenance medication over the follow-up period and tended to have spent more time in complete remission. EV+ schizophrenic subjects also had higher morbid risk for schizophrenia in their first ...
http://hub.hku.hk/handle/10722/175702
*  The Role of Early Adverse Life Events in the Etiology of Depression and Posttraumatic Stress Disorder - HEIM - 1997 - Annals of...
Mary Gilliam, Erika E. Forbes, Peter J. Gianaros, Kirk I. Erickson, Lauretta M. Brennan, Daniel S. Shaw, Maternal depression in childhood and aggression in young adulthood: evidence for mediation by offspring amygdala-hippocampal volume ratio, Journal of Child Psychology and Psychiatry, 2015, 56, 10, ...
http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1997.tb48279.x/abstract
*  Publications [#251230] of Avshalom Caspi
The binding protein FKBP5 is an important modulator of the function of the glucocorticoid receptor, the main receptor of the stress hormone system. This turns the FKBP5 gene into a key candidate for gene-environment interactions, which are considered critical for pathogenesis of stress-related disorders. The authors explored gene-environment interactions between FKBP5 gene variants and adverse life events in predicting the first occurrence of a major depressive episode.The analyses were based on 884 Caucasians in a 10-year prospective community study. At baseline, they were 14-24 years old and did not fulfill criteria for a major depressive episode. The DSM-IV-based Munich Composite International Diagnostic Interview was used to assess adverse life events preceding baseline and major depressive episodes during follow-up. On the basis of previous findings, five single-nucleotide polymorphisms (SNPs) within the FKBP5 gene were selected for ...
http://fds.duke.edu/db/aas/pn/faculty/avshalom.caspi/publications/251230
*  Stressful Life Events and the Metabolic Syndrome | Diabetes Care
The key finding in the present study is that individuals who reported extremely stressful life events within finance- and work-related life domains had significantly higher odds for having the metabolic syndrome. The risk was further increased according to accumulation of stressful finance-related events and according to having at least three events in any of the life domains we measured, namely finance, work, social relationships, health, and housing. Accumulation of stressful finance- and work-related life events and having at least three stressful events in any of the life domains also associated significantly with insulin resistance, obesity, and triglycerides. The associations were not confounded by sex, age, lifestyle, or family history of diabetes.. Our findings are in agreement with previous studies (9-13) by showing ...
http://care.diabetesjournals.org/content/33/2/378.full
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=12352
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=12420
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=13203
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=16405
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=17254
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=17800
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=19425
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=4894
*  10 Most Stressful Life Events: the Holmes and Rahe Stress Scale
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
https://paindoctor.com/top-10-stressful-life-events-holmes-rahe-stress-scale/?replytocom=6308
*  Lives change @ your library | HeraldNet.com
Okay, guys. Buckle up! This is going to be a wordy post, but I promise it will be an extremely rewarding read. Last week was National Library Week. Libraries across the country celebrated in various ways, but we all shared the same theme: Lives Change @ Your Library. Here at EPL we talked to you. My colleagues and I, armed with cookies and a laptop, asked you to share your library stories. We asked you to tell us what you love about the library and how it may have impacted your life. I have to say that the experience was both entertaining and very humbling. The shorter stories I tweeted; the longer ones I will share with you here. Know that every single one of you warmed my heart and made me thankful that I'm able to work with people like you.
http://www.heraldnet.com/life/lives-change-your-library/
*  China Sodium Lauryl Ether Sulfate / SLES/SLES 70% - China SLES, SLES 70%
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http://qianmiaonuo.en.made-in-china.com/product/DoNmifFyAOpE/China-Sodium-Lauryl-Ether-Sulfate-SLES-SLES-70-.html
*  Molecular signatures of major depression - MRCPHRU
© 2015 Elsevier Ltd All rights reserved. Adversity, particularly in early life, can cause illness. Clues to the responsible mechanisms may lie with the discovery of molecular signatures of stress, some of which include alterations to an individual's somatic genome. Here, using genome sequences from 11,670 women, we observed a highly significant association between a stress-related disease, major depression, and the amount of mtDNA (p = 9.00 × 10 | sup | -42 | /sup | , odds ratio 1.33 [95% confidence interval [CI] = 1.29-1.37] ) and telomere length (p = 2.84 × 10 | sup | -14 | /sup | , odds ratio 0.85 [95% CI = 0.81-0.89]). While both telomere length and mtDNA amount were associated with adverse life events, conditional regression analyses showed the molecular changes were contingent on the depressed state. We tested this hypothesis with experiments in mice, demonstrating that stress causes both molecular changes, which are ...
https://www.mrc-phru.ox.ac.uk/publications/523540
*  Biological correlates of the Allais paradox: Ingenta Connect
We conducted a questionnaire study with student subjects to look for explicit correlations between selected biological characteristics of the subjects and manifestation of the Allais paradox in the pattern of their choices between sets of two pairs of risky prospects. We found that particular characteristics, such as gender, menstrual cycle, mother's age at delivery, parenthood, second- to fourth-digit ratio, perceived negative life events, and emotional state, can be related to the paradox. Women, particularly when not menstruating, are less susceptible to the paradox. Those born to not-too-young mothers are also less prone to the paradox. The same holds true for men who have fathered children and had been exposed to high levels of prenatal testosterone, people who had experienced many negative life events, and those who were anxious, excited, aroused, happy, active, or fresh at the time of the experiment. Further, left-handers and atheists ...
http://www.ingentaconnect.com/content/routledg/raef/2013/00000045/00000005/art00002