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*  "Large-conductance calcium-activated potassium channels in neonatal rat" by F Franciolini, Ron C. Hogg et al.
the single-channel slope conductance was linear in the voltage range -60/+60 mV, and was 207±19 pS. Na+ ions were not ... Channel activity increased with the cytoplasmic free Ca2+ concentration ([Ca2+]i) with a Hill plot giving a half-saturating [ ... The resting activity was consistent with a [Ca2+]i ,100 nM and the increased channel activity evoked by ionomycin was ... Ionomycin (1-10 μM) increased BK channel activity in the cell-attached recording configuration. ...
http://ro.uow.edu.au/ihmri/705/
*  Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage...
The large-conductance calcium-activated potassium channels (BKCa) and voltage-gated sodium channels were expressed in cortical ... roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels. ... Large-conductance calcium-activated potassium current modulates excitability in isolated canine intracardiac neurons. Am J ... The large conductance Ca2+-activated K+ (BKCa) channel currents in response to resveratrol were examined in the condition of ...
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-016-0259-y
*  Kcnmb4 MGI Mouse Gene Detail - MGI:1913272 - potassium large conductance calcium-activated channel, subfamily M, beta member 4
KCNMB4, potassium calcium-activated channel subfamily M regulatory beta subunit 4. Orthology source: HomoloGene, HGNC ... J:250373 Whitmire LE, et al., Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule ... potassium large conductance calcium-activated channel, subfamily M, beta member 4. * Synonyms ...
http://www.informatics.jax.org/marker/MGI:1913272
*  anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody (Alexa Fluor 647)...
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody (Alexa Fluor 647) ... Itemanti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody (Alexa Fluor 647) ... anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody (Alexa Fluor 647) from ... anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody (Alexa Fluor 647) ...
https://www.biocompare.com/9776-Antibodies/4170105-anti-KCNMB1-Maxi-Potassium-channel-beta-antibody-Alexa-Fluor-647/
*  Frontiers | Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel...
... and BK channel mutations have been linked to seizure disorders. Modulation of BK channel gating is well characterized, ... and BK channel mutations have been linked to seizure disorders. Modulation of BK channel gating is well characterized, ... Fluorogen activating peptides (FAPs) are well-suited for trafficking and physiological studies due to the binding of malachite ... Fluorogen activating peptides (FAPs) are well-suited for trafficking and physiological studies due to the binding of malachite ...
https://www.frontiersin.org/articles/10.3389/fncel.2017.00337/full
*  Modulation of the BK channel by estrogens: examination at single channel level. - Oxford Neuroscience
... associated with the channel. The present investigation demonstrates that 17beta-oestradiol activates the BK channel complex by ... We also present evidence that more than one beta1-subunit is required to facilitate binding of 17beta-oestradiol to the channel ... Oestrogen has been reported to lower blood pressure by increasing BK channel open probability through direct binding to the ... BK channels regulate vascular tone by hyperpolarizing smooth muscle in response to fluctuating calcium concentrations. ...
https://www.neuroscience.ox.ac.uk/publications/115975
*  OPUS at UTS: A Novel Family of Insect-Selective Peptide Neurotoxins Targeting Insect Large-Conductance Calcium-Activated K(+)...
Potassium Channels, Calcium-Activated. en_US. dc.subject.mesh. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ... A Novel Family of Insect-Selective Peptide Neurotoxins Targeting Insect Large-Conductance Calcium-Activated K(+) Channels ... A Novel Family of Insect-Selective Peptide Neurotoxins Targeting Insect Large-Conductance Calcium-Activated K(+) Channels ... It is noteworthy that kappa-TRTX-Ec2 toxins were all found to be high-affinity blockers of insect large-conductance calcium- ...
https://opus.lib.uts.edu.au/handle/10453/18610
*  Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels | Science Signaling
... local increases in calcium. Calcium sparks activated a potassium channel that induces vasodilation. Thus, constriction of ... Activation of Ca2+-sensitive, large-conductance potassium (BK) channels in vascular smooth muscle cells (VSMCs) by local, ... Oxidant-activated PKG was required to trigger Ca2+ sparks, BK channel activity, and vasodilation in response to pressure. VSMCs ... Thus, the absence of oxidative activation of PKG disabled the BK channel-mediated negative feedback regulation of ...
http://stke.sciencemag.org/content/9/449/ra100
*  SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila
The Drosophila melanogaster large conductance calcium-activated potassium channel SLOWPOKE (SLO) undergoes modulation via its ... However, the downstream consequences of ion channel modulation remain largely undetermined. ... There is ample evidence that ion channel modulation by accessory proteins within a macromolecular complex can regulate channel ...
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023343
*  The inhibition of voltage-gated potassium channels (Kv) plays a significant role - Small Molecule Inhibitors of Protein...
... channels in vascular easy muscle mass cells Kv ATP-sensitive K+ inward rectification and large conductance Ca2+-activated K+ [5 ... The inhibition of Kv channels may be involved in hypoxic vasoconstriction through prolonging repolarization period for calcium ... The inhibition of voltage-gated potassium channels (Kv) plays a significant role. by Ross Marshall ... The inhibition of voltage-gated potassium channels (Kv) plays a significant role in the cerebral hypoxia-induced cell death. of ...
http://welbourneprimary.com/the-inhibition-of-voltage-gated-potassium-channels-kv-plays-a-significant-role/
*  Modulation of Kv Channel Expression and Function by TCR and Costimulatory Signals during Peripheral CD4+ Lymphocyte...
A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes. J. Biol. Chem. 272:32723-32726. ... Kv channels in naive and in vivo primed CD4+ T cells were maximally activated with a large step depolarization (120 mV) from ... A charybdotoxin-insensitive conductance in human T lymphocytes: T cell membrane potential is set by distinct K+ channels. J. ... T cell activation is regulated by voltage-dependent and calcium-activated potassium channels. J. Immunol. 156:1425-1430. ...
http://jem.rupress.org/content/196/7/897
*  Large-Conductance Calcium-Activated Potassium Channels - Maxi-K Channels Summary Report | CureHunter
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by ... either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical ... Potassium Channels: 2108*Calcium-Activated Potassium Channels: 183*Large-Conductance Calcium-Activated Potassium Channels: 162* ... Potassium Channels: 2108*Calcium-Activated Potassium Channels: 183*Large-Conductance Calcium-Activated Potassium Channels: 162* ...
http://www.curehunter.com/public/keywordSummaryD051036-Large-Conductance-Calcium-Activated-Potassium-Channels-Maxi-K-Channels.do
*  Cytochrome P-450 Epoxygenase Metabolites of Docosahexaenoate Potently Dilate Coronary Arterioles by Activating Large...
large-conductance calcium-activated potassium channel. EDP. epoxydocosapentaenoic acid. EEQ. epoxyeicosaquatraenoic acid. DHDP ... of Docosahexaenoate Potently Dilate Coronary Arterioles by Activating Large-Conductance Calcium-Activated Potassium Channels. ... of Docosahexaenoate Potently Dilate Coronary Arterioles by Activating Large-Conductance Calcium-Activated Potassium Channels. ... of Docosahexaenoate Potently Dilate Coronary Arterioles by Activating Large-Conductance Calcium-Activated Potassium Channels. ...
http://jpet.aspetjournals.org/content/303/2/768
*  β Subunits Modulate Alternatively Spliced, Large Conductance, Calcium-Activated Potassium Channels of Avian Hair Cells |...
Large conductance, calcium-activated potassium (BK) channels play a prominent role in vertebrate hair cell function. BK ... β Subunits Modulate Alternatively Spliced, Large Conductance, Calcium-Activated Potassium Channels of Avian Hair Cells. ... β Subunits Modulate Alternatively Spliced, Large Conductance, Calcium-Activated Potassium Channels of Avian Hair Cells ... β Subunits Modulate Alternatively Spliced, Large Conductance, Calcium-Activated Potassium Channels of Avian Hair Cells ...
http://www.jneurosci.org/content/20/5/1675
*  Characterization of Large-Unitary-Conductance Calcium-Activated Potassium Channels in Planar Lipid Bilayers | SpringerLink
These channels are thought to be involved in the regulation of different cellular... ... In this chapter we discuss the data obtained for a calcium-activated potassium channel of large unitary conductance. ... In this chapter we discuss the data obtained for a calcium-activated potassium channel of large unitary conductance. These ... Characterization of Large-Unitary-Conductance Calcium-Activated Potassium Channels in Planar Lipid Bilayers. ...
https://link.springer.com/chapter/10.1007/978-1-4684-5077-4_20
*  NAVER Academic | Nitric oxide deficit in chronic intermittent hypoxia impairs large conductance calcium-activated potassium...
... and ionic channels remain unclear. We examined the hypothesis that hippocampal NO deficit impairs the activity of large ... conductance calcium-activated potassium (BK) channels in rats with chronic IH, mimicking conditions in patients with sleep ... We found that the open probability of BK channels remarkably decreased in the CA1 pyramidal neurons in a time-dependent manner ... NO donors, SNP or DETA/NO, significantly restored the activity of BK channels in the IH neurons, which was prevented by ...
https://academic.naver.com/article.naver?doc_id=66430431
*  Kcnmb4 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 4 (Kcnmb4), (10ug) -...
Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 4 (Kcnmb4), (10ug), 10 µg. ... Home » cDNA » Mouse cDNA » Kcnmb4 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta ... MC210183 Kcnmb4 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 4 (Kcnmb4 ... Properties for Kcnmb4 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 4 ( ...
https://www.acris-antibodies.com/cdna/mouse-cdna/kcnmb4-untagged-mouse-potassium-large-conductance-calcium-activated-channel-subfamily-m-beta-member-4-kcnmb4-10ug-mc210183.htm
*  Kcnmb1 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1), (10ug) -...
Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1), (10ug), 10 µg. ... Home » cDNA » Mouse cDNA » Kcnmb1 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta ... MC207312 Kcnmb1 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1 ... Properties for Kcnmb1 (untagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 1 ( ...
https://www.acris-antibodies.com/cdna/mouse-cdna/kcnmb1-untagged-mouse-potassium-large-conductance-calcium-activated-channel-subfamily-m-beta-member-1-kcnmb1-10ug-mc207312.htm
*  BK channels control cerebellar Purkinje and Golgi cell rhythmicity in vivo.
As cerebellar Purkinje cells express the major regulatory elements of calcium control and represent the sole integrative output ... Calcium signaling plays a central role in normal CNS functioning and dysfunction. ... Large-Conductance Calcium-Activated Potassium Channels / metabolism*. Male. Mice. Models, Genetic. Models, Statistical. ... Small (SK) and large (BK) conductance Ca2+-activated potassium channels contribute to the action potential shape and spike ...
http://www.biomedsearch.com/nih/BK-Channels-Control-Cerebellar-Purkinje/19956720.html
*  Cell biology and pathology of podocytes. - PubMed - NCBI
... large-conductance calcium-activated potassium channel (also known as BK channel); mGluR, metabotropic glutamate receptor; NEP, ... transient receptor potential canonical channels 6 and 5; CathL, cathepsin L; PKA/CamKII, protein kinase A/calcium-calmodulin- ... In this review, we take a membrane biologist's view of the podocyte, examining the many membrane receptors, channels, and other ... calcium-sensing receptor; CXCR/CCR, C-X-C/C-C chemokine receptor; FAT, protocadherin FAT1; Fc neo R, neonatal Fc receptor; FGFR ...
https://www.ncbi.nlm.nih.gov/pubmed/22054238?access_num=22054238&link_type=MED&dopt=Abstract
*  Plus it
2000) Relationship between large conductance calcium-activated potassium channel and bursting activity. Brain Res 860:21-28. ... Neuronal excitability can be enhanced by closing large-conductance Ca2-activated K potassium channels (Shao et al., 1999; Traub ... 2003) Calcium-activated potassium channels: multiple contributions to neuronal function. Neuroscientist 9:181-194. ... 2002) Channels underlying neuronal calcium-activated potassium currents. Prog Neurobiol 66:345-353. ...
http://www.jneurosci.org/content/28/15/4028
*  Potassium channels in the human myometrium. - Semantic Scholar
This article reviews the contribution of potassium (K(+)) channels to human uterine excitability. Experimental Physiology (2001 ... in comparison with the non-labour state and is manifest at the membrane level via the activity of uterine ion channels. ... Functional Coupling of 3-Adrenoceptors and Large Conductance Calcium-Activated Potassium Channels in Human Uterine Myocytes. * ... Potassium channels in the human myometrium.. @article{Khan2001PotassiumCI, title={Potassium channels in the human myometrium ...
https://www.semanticscholar.org/paper/Potassium-channels-in-the-human-myometrium.-Khan-Matharoo-Ball/830b903bbc782c07cf881359756c39e598f94b91
*  Pharmaceuticals | Free Full-Text | Calcium Channel Blockers as Tocolytics: Principles of Their Actions, Adverse Effects and...
Their mechanism of action in tocolysis involves the blockade of L-type Ca2+ channels, influenced by the Ca2+-activated K+ ... channels, beta-adrenergic receptors (β-ARs) and sexual hormones. In clinical practice, most experience has been gained with the ... Dihydropyridine Ca2+ channel blockers (CCBs) are widely accepted in the treatment of premature labour. ... Wu, S.N.; Wu, A.Z.; Lin, M.W. Pharmacological roles of the large-conductance calcium-activated potassium channel. Curr. Top. ...
http://www.mdpi.com/1424-8247/6/6/689/htm
*  GAL - Galanin peptides precursor - Homo sapiens (Human) - GAL gene & protein
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1 ... positive regulation of large conductance calcium-activated potassium channel activity Source: UniProtKB ,p>Inferred from Direct ... Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. ... Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. ...
http://www.uniprot.org/uniprot/P22466