The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | Journal of Clinical ImmunologyThe 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | Journal of Clinical Immunology
... natural killer cells; Nl: normal; sd: syndrome; SLE: systemic lupus erythematous disease; Tc: T cells; TCR: T cell receptor; XL ... natural killer; SCID: severe combined immunodeficiency; Tc: T cells; TCR: T cell receptor; Treg: regulatory T cells; XL: X- ... natural killer cells; RNA: ribonucleic acid; sd: syndrome; Tc: T cells; TLR3: Toll-like receptor type 3; VZV: varicella zoster ... natural killer cells; WBC: white blood cells; XL: X-linked transmission ...
https://link.springer.com/article/10.1007/s10875-017-0465-8
Evolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLinkEvolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLink
Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin Exp Immunol. ... The role of natural killer cells in autoimmune liver disease: a comprehensive review. J Autoimmun. 2013;46:55-65. ... Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med. 2001;194:1801-1811 ... Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med ...
https://link.springer.com/article/10.1007/s10620-018-5351-6?error=cookies_not_supported&code=6475bd1b-5d51-42ac-b16a-93df0268662b
Modulation of natural killer activity by thymosin alpha 1 and interferon | SpringerLinkModulation of natural killer activity by thymosin alpha 1 and interferon | SpringerLink
... a major biological modifier of natural killer (NK) cytolytic activit ... Interferons and natural killer cells: interacting systems of non specific host defense. In: NK cells and other natural effector ... Hurme M, Sihvola M (1984) High expression of the Thy-1 antigen on natural killer cells recently derived from bone marrow. Cell ... Timonen T, Ortaldo JR, Herberman RB (1982) Analysis by a single cell cytotoxicity assay of natural killer (NK) cell frequencies ...
https://link.springer.com/article/10.1007/BF00205574?error=cookies_not_supported&code=b67cfba8-d04a-4960-b401-541f223217b1
Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell | DiabetologiaIslet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell | Diabetologia
... which ultimately leads to the loss of functional pancreatic beta cells. M ... T cells are insulin-reactive; and CD8+ T cells play a major role as beta cell killers [6, 7]. Immunohistopathological studies ... The notion of beta cell functional heterogeneity is increasingly accepted as a natural and biologically relevant feature of ... autoreactive T cells differentiate into killers by engaging beta cell antigens on local antigen-presenting cells; initiating ...
https://link.springer.com/article/10.1007/s00125-023-05970-z
Progress in mesenchymal stem cell-based therapy for acute liver failure | Stem Cell Research & TherapyProgress in mesenchymal stem cell-based therapy for acute liver failure | Stem Cell Research & Therapy
Several types of stem cells have been used to study liver diseases; mesenchymal stem cells are most commonly used because they ... In recent years, a growing number of studies have shown that stem cells can effectively treat acute liver failure. ... The aims of this article are to review the current knowledge regarding therapeutic mechanisms of mesenchymal stem cells in ... to discuss recent advancements in preclinical and clinical studies in the treatment of mesenchymal stem cells, and to summarize ...
https://link.springer.com/article/10.1186/s13287-018-0972-4
Impacts of COVID-19 pandemic on urban park visitation: a global analysis | Journal of Forestry ResearchImpacts of COVID-19 pandemic on urban park visitation: a global analysis | Journal of Forestry Research
2014). Spending time in parks and other natural areas can activate Natural Killer (NK) cells in humans. NK cells are important ... Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S (2008) Functions of natural killer cells. Nat Immunol 9(5):503-510 ... Health effects of a forest environment on natural killer cells in humans: an observational pilot study. Oncotarget 9(23):16501 ... Li Q, Morimoto K, Nakadai A, Inagaki H, Katsumata M, Shimizu T, Kagawa T (2007) Forest bathing enhances human natural killer ...
https://link.springer.com/article/10.1007/s11676-020-01249-w
An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen...An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen...
NK cells have been seen as potential agents in adoptive immunotherapy for cancer. The main challenge for the success of this ... Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas ... Interactions between human mesenchymal stem cells and natural killer cells. Stem Cells,24, 74-85. ... Luci, C., & Tomasello, E. (2008). Natural killer cells: Detectors of stress. International Journal of Biochemistry & Cell ...
https://link.springer.com/article/10.1007/s12033-020-00250-2?error=cookies_not_supported&code=e16e305d-9ffd-4c40-ae3c-ebc7db7e9706
The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies |...The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies |...
Park E, Lee J, Jeong D, Han S, Jeon Y (2015) Natural killer cell activity in patients with major depressive disorder treated ... nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), inflammasomes, Toll-like receptor 4 (TLR4), peroxisome ... Sertraline ameliorates inflammation in cums mice and inhibits TNF-α-induced inflammation in microglia cells. Int ...
https://link.springer.com/article/10.1007/s10787-020-00777-5?error=cookies_not_supported&code=4bb9217c-ecb1-4917-b520-866b469e3088
Therapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings | 3 BiotechTherapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings | 3 Biotech
The sulfated derivative (200 μg/g/day) showed an increase in natural killer cells (NK cells) up to 76.1 %. It suggested that ... Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. ... Fucoidan decreased cell viability and induced apoptosis of the carcinoma cells, through activation of caspases 9 and 3 and the ... cell line. Fucoidan treatment of HL-60 cells induced activation of caspases 8, 9, and 3, the cleavage of Bid, and altered ...
https://link.springer.com/article/10.1007/s13205-012-0061-9
Application of artificial intelligence in nuclear medicine and molecular imaging: a review of current status and future...Application of artificial intelligence in nuclear medicine and molecular imaging: a review of current status and future...
Weakly supervised deep learning for determining the prognostic value of 18F-FDG PET/CT in extranodal natural killer/T cell ... It seems obvious that AI and total body scanners are natural partners to tackle this problem. ...
https://link.springer.com/article/10.1007/s00259-022-05891-w
Case-control meta-analysis of blood DNA methylation and autism spectrum disorder | Molecular AutismCase-control meta-analysis of blood DNA methylation and autism spectrum disorder | Molecular Autism
... for sex and surrogate variables that reflect major sources of biological variation and technical confounding such as cell type ... CD4 T cells, CD8 T cells, B cells, and natural killer cells) using the estimateCellCounts() function in the minfi R package. ... Ectoderm cell lineage-derived buccal cells, obtained from 47 ASD cases and 48 controls born to mothers aged 35 and older, have ... Finally, for all SEED and SSC samples, we estimated cell type proportions for six different cell types (granulocytes, monocytes ...
https://link.springer.com/article/10.1186/s13229-018-0224-6
Targeting Macrophages for Tumor Therapy | SpringerLinkTargeting Macrophages for Tumor Therapy | SpringerLink
... as one of the most abundant tumor-infiltrating cells, play an important role in tumor development and metastasis. The frequency ... Cell-membrane immunotherapy based on natural killer cell membrane coated nanoparticles for the effective inhibition of primary ... Koh MY, Sayegh N, Agarwal N. Seeing the forest for the trees-single-cell atlases link CD8(+) T cells and macrophages to disease ... Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nat Cell Biol ...
https://link.springer.com/article/10.1208/s12248-023-00845-y?error=cookies_not_supported&code=e2b30916-fcbf-4944-8c5a-e9a0915ba524
Extracellular Vesicles Regulate Cancer Metastasis | SpringerLinkExtracellular Vesicles Regulate Cancer Metastasis | SpringerLink
Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions. ... Xu J, Liao K, Zhou W (2018) Exosomes regulate the transformation of cancer cells in cancer stem cell homeostasis. Stem Cells ... Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells. Int ... Becker A, Thakur BK, Weiss JM, Kim HS, Peinado H, Lyden D (2016) Extracellular vesicles in cancer: cell-to-cell mediators of ...
https://link.springer.com/chapter/10.1007/978-3-030-67171-6_11?error=cookies_not_supported&code=7fd561a7-23b8-4b41-84e1-80f7bae7c915
Pharmacokinetic modelling of N-(4-[18F]fluorobenzoyl)interleukin-2 binding to activated lymphocytes in an xenograft model of...Pharmacokinetic modelling of N-(4-[18F]fluorobenzoyl)interleukin-2 binding to activated lymphocytes in an xenograft model of...
Ghiringhelli F, Ménard C, Martin F, Zitvogel L. The role of regulatory T cells in the control of natural killer cells: ... Role of natural killer T cells in the mouse colitis-associated colon cancer model. Scand J Immunol 2012;75(1):16-26. ... During activation, immune cells overexpress multimeric IL-2R, which are able to sustain immune cell proliferation and cell ... MicroPET images showed clear [18F]FB-IL2 uptake at the cell inoculation site, even for the smallest number of injected cells ( ...
https://link.springer.com/article/10.1007/s00259-012-2176-y
The Influence of Selected Insecticides on the Oxidative Response of Atta sexdens (Myrmicinae, Attini) Workers | Neotropical...The Influence of Selected Insecticides on the Oxidative Response of Atta sexdens (Myrmicinae, Attini) Workers | Neotropical...
Bioassays performed has shown that Mg1-complex is not a fast-killer and acts slowly in workers of A. sexdens (Oliveira 2012). ... Bonomo MM, Fernandes JB, Carlos RM, Fernandes MN (2020) Biochemical and genotoxic biomarkers and cell cycle assessment in the ... Masella R, Di Benedetto R, Varì R et al (2005) Novel mechanisms of natural antioxidant compounds in biological systems: ... Hoshizaki DK (2005) Fat-cell development. In: Gilbert LI, Iatrou K, Gill S (eds) Complete Molecular Insect Science. Elsevier, ...
https://link.springer.com/article/10.1007/s13744-023-01077-7
Review: The Use of Bench-Scale Tests to Determine Toxic Organic Compounds in Fire Effluents and to Subsequently Estimate Their...Review: The Use of Bench-Scale Tests to Determine Toxic Organic Compounds in Fire Effluents and to Subsequently Estimate Their...
For waters in natural environments, the Microtox® Toxicity Test is used to evaluate the inhibition of the luminescence in the ... In vitro studies use human cells, isolated tissues and organs outside the body to investigate the toxic and adverse reactions ... on fire toxicity showed that brominated and antimony-containing flame retardants increase the yields of the two biggest killers ... In the presence of pollutant agents, the natural bioluminescence of V. fischeri is reduced, and the toxicity is expressed as ...
https://link.springer.com/article/10.1007/s10694-020-01065-y
The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method |...The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method |...
For example, 25 years ago, we diagnosed lung cancer either as small cell lung cancer or non-small cell lung cancer. This simple ... Cyranoski D (2020) Profile of a killer: the complex biology powering the coronavirus pandemic. Nature. 581(7806):22-26 ... integration of physiological PK/PD models and intermediate markers of pharmacological effects with the natural evolution of the ... Ahn JC, Teng PC, Chen PJ, Posadas E, Tseng HR, Lu SC et al (2020) Detection of circulating tumor cells and their implications ...
https://link.springer.com/article/10.1007/s00228-020-03044-2