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Lyons, MA; Brown, AJ (1999). "7-Ketocholesterol". Int. J. Biochem. Cell Biol. 31 (3-4): 369-75. doi:10.1016/s1357-2725(98)00123 ... symptoms of aging such as atherosclerosis are also attributed to radical induced oxidation of cholesterol to 7-ketocholesterol ...

Keywords: 7-ketocholesterol; CCL18/PARC; Chitotriosidase; Diagnosis; NP-C suspicion index; Niemann-Pick disease type C; ... Filipin staining and 7-ketocholesterol (7-KC) measurements were performed in all patients with NP-C gene mutations, where ...

Oxidation of LDL may also lead to generation of oxidized derivatives of cholesterol (i.e. 7-ketocholesterol - 7-ketoCh), which ... Concentration of anti-7-ketocholesterol antibodies in serum from patients after heart transplantation T Wielkoszyński, M ... Oxidation of LDL may also lead to generation of oxidized derivatives of cholesterol (i.e. 7-ketocholesterol - 7-ketoCh), which ...

Erridge, C., Webb, D. J., & Spickett, C. M. (2007). 25-hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol ... Erridge, Clett ; Webb, David J. ; Spickett, Corinne M. / 25-hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol ... Erridge, C, Webb, DJ & Spickett, CM 2007, 25-hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol upregulate ... Dive into the research topics of 25-hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 ...

The 7-ketocholesterol-cholesterol mixture was prepared as previously described50. Briefly, 15 mg/ml of 7KC and cholesterol ( ... 6a,b). As assessed by the lipid order coefficient, both the 7-ketocholesterol and GML treatment caused overall disorder, but ... APBTs treated with 10 μg/ml of GML, 0.1% ethanol, or 7-ketocholesterol were stained with Di-4-ANEPPDHQ. Fluorescent emissions ... We also used a treatment consisting of 7-ketocholesterol, cholesterol, and methyl-β-cyclodextrin as a positive control because ...

Cholestan-3β,5α,6β-triol (C-triol) and 7-ketocholesterol (7-KC) have been proposed as new biomarkers for the diagnosis of ... Evaluation of plasma cholestane-3β,5α,6β-triol and 7-ketocholesterol in inherited disorders related to cholesterol metabolism. ... levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection.. ...

For example, 7-ketocholesterol was negatively correlated with indoxyl sulfate and sphingosine (Figure 5D). In addition, ... However, 7-ketocholesterol and 9S,10S,13R-trihydroxyoctadec-11E-enoic acid were negatively associated with these changes ( ...

Atherosclerosis is associated with the buildup of cholesterol and its oxidized derivatives (particularly 7-ketocholesterol) in ... We identified numerous bacteria having the ability to transform cholesterol and 7-ketocholesterol. Most of these species ... and we have used this enzyme directly to reduce the toxicity of 7-ketocholesterol, the major toxic oxysterol, to cultured human ... Because we humans can tolerate several decades of buildup in unwanted biochemicals like 7-ketocholesterol and A2E without undue ...

... of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol ...

Lipoprotein(a): 7-ketocholesterol and cancer (1) * LIRKO mice (1) (1) * LIRKO mice (2) (1) ...

Lipoprotein(a): 7-ketocholesterol and cancer (1) * LIRKO mice (1) (1) * LIRKO mice (2) (1) ...

7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B ...

E. Pedruzzi, C. Guichard, V. Ollivier et al., "NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum ...

... against dietary cholesterol-induced endothelial dysfunction by promoting cholesterol efflux and release of 7-ketocholesterol ...

Jang, E.R.; Lee, C.S. 7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent ...

... measured as 7-beta-hydroxycholesterol and 7-ketocholesterol.) Subjects with atherosclerosis were found to have plasma vitamin E ... 7-beta-hydroxycholesterol and 7-ketocholesterol. Plaques obtained following the surgery were also analyzed for these factors ...

7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti ...

7-Ketocholesterol. 6-Hydroxynicotinic acid. 7-Methylguanine. 6-Methyladenine. 7-Methylxanthine. 6-Methyladenine. ...

7-Ketocholesterol (CAS#566-28-9); 7-Oxocholesteryl acetate (CAS#809-51-8); 27-Hydroxycholesterol (CAS#20380-11-4); Cholest-4,6- ... 7-Ketocholesterol (CAS#566-28-9); 7-Oxocholesteryl acetate (CAS#809-51-8); 27-Hydroxycholesterol (CAS#20380-11-4); Cholest-4,6- ...

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Massey JB, Pownall HJ: The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics ... The incorporation of the oxysterol 7-ketocholesterol (7KC) and the incorporation of the polyunsaturated fatty acid (PUFA) ...

Effect of PCSK9 inhibition on plasma levels of small dense low density lipoprotein-cholesterol and 7-ketocholesterol. Mahmood, ...

William J. Griffiths, Eylan Yutuc, Jonas Abdel-Khalik, Peter J. Crick, Thomas Hearn, Alison Dickson, Brian W. Bigger, Teresa Hoi-Yee Wu, Anu Goenka, Arunabha Ghosh, Simon A. Jones, Douglas F. Covey, Daniel S. Ory, Yuqin ...

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... purified from the extracted lipids of oxLDL was identified as 7-ketocholesterol-9-carboxynonanoate (i.e., 9-oxo-9-(7- ... purified from the extracted lipids of oxLDL was identified as 7-ketocholesterol-9-carboxynonanoate (i.e., 9-oxo-9-(7- ... purified from the extracted lipids of oxLDL was identified as 7-ketocholesterol-9-carboxynonanoate (i.e., 9-oxo-9-(7- ... purified from the extracted lipids of oxLDL was identified as 7-ketocholesterol-9-carboxynonanoate (i.e., 9-oxo-9-(7- ...

Ketocholesterols. Below are MeSH descriptors whose meaning is more specific than "Dehydrocholesterols". ...

Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury. Koh Sally Shuxian, et al. Neuromolecular medicine 2020 ...

... tackle cholesterol derivatives such as 7-ketocholesterol. These toxic molecules have no known biological function, and the ...