A microfluidic array for real-time live-cell imaging of human and rodent pancreatic islets
The device is based on hydrodynamic trapping principle and enables real-time analysis of islet cellular responses to insulin ... we present a microfluidic array for high-resolution imaging of individual pancreatic islets. ... Islets of Langerhans / cytology* * Lab-On-A-Chip Devices* * Mice * Molecular Imaging / instrumentation* ... A microfluidic array for real-time live-cell imaging of human and rodent pancreatic islets Lab Chip. 2016 Apr 21;16(8):1466-72. ...
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets
... Discov Med. 2010 Jun;9(49): ... Islets of Langerhans / metabolism* * Proteins / genetics * Proteins / metabolism* * Proteomics* * Tissue Array Analysis ... Also beta-2-microglobulin and ubiquitin carboxyl-terminal hydrolase isozyme L1 were expressed in a majority of islet cells, ... In the present study, five proteins highly expressed in pancreatic islets with no expression in the surrounding exocrine ...
Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells
Islets of Langerhans / drug effects * Islets of Langerhans / metabolism* * RNA, Messenger / analysis* ...
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations...
Islets of Langerhans / physiopathology* * Middle Aged * Monocytes / metabolism * Receptor, Insulin / metabolism Substances * ...
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
Islets of Langerhans / cytology * Islets of Langerhans / growth & development* * Kidney / cytology * Mice ...
Insulin secretion and sensitivity in space flight: diabetogenic effects
Taken together, space flight research, ground-based studies, and bioreactor studies of pancreatic islets of Langerhans support ... and amino acid metabolism in pancreatic islets of Langerhans cultured in a ground-based cell culture bioreactor that mimics ...
The role of triple immunosuppressive treatment in the successful implantation of islet grafts
Islets of Langerhans Transplantation / immunology* * Islets of Langerhans Transplantation / physiology * Prednisolone / ... The role of triple immunosuppressive treatment in the successful implantation of islet grafts Transplant Proc. 1999 Nov;31(7): ...
Stocker CJ[Author] - Search Results - PubMed
Isolation and Purification of Rodent Pancreatic Islets of Langerhans. ODowd JF, Stocker CJ. ODowd JF, et al. Among authors: ...
Systematic prevention of bubble formation and accumulation for long-term culture of pancreatic islet cells in microfluidic...
Islets of Langerhans / cytology* * Islets of Langerhans / metabolism * Mice * Mice, Inbred C57BL ... In addition to demonstrating normal cell viability and islet morphology, post-cultured islets exhibited normal insulin ... Systematic prevention of bubble formation and accumulation for long-term culture of pancreatic islet cells in microfluidic ... perifusion system equipped with the bubble trap was successfully applied for long-term culture of mouse pancreatic islets with ...
Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta...
Islets of Langerhans / cytology * Islets of Langerhans / drug effects* * Islets of Langerhans / metabolism ...
Sandker G[au] - Search Results - PubMed
Noninvasive Monitoring of Glycemia-Induced Regulation of GLP-1R Expression in Murine and Human Islets of Langerhans. Buitinga M ...
3D Printed Vascularized Device for Subcutaneous Transplantation of Human Islets
However, islet transplantation is associated with several challenges including function-loss associated with dispersion and ... Transplantation of pancreatic islets or stem cell derived insulin secreting cells is an attractive treatment strategy for ... Islets of Langerhans Transplantation / methods* * Islets of Langerhans* / blood supply * Islets of Langerhans* / cytology ... here we present a novel 3D printed and functionalized encapsulation system for subcutaneous engraftment of islets or islet like ...