Current Trend and Pro-survival Approaches for Augmenting Stem Cell Viability
| Bentham Science
Pre-conditioned mesenchymal stem cells ameliorate renal ischemic injury in rats by augmented survival and engraftment. J. ... Li, L.; Guan, Q.; Dai, S.; Wei, W.; Zhang, Y. Integrin β1 increases stem cell survival and cardiac function after myocardial ... Hu, C.; Li, L. Preconditioning influences mesenchymal stem cell properties in vitro and in vivo hypoxia preconditioning for ... Keywords: Viability, mesenchymal stem cell, preconditioning, pro-survival strategies, PI3K/AKT, HIF1. ...
Implementation of an open-source customizable minimization program for allocation of patients to parallel groups in clinical...
Remote ischemic preconditioning in the management of intermittent claudication: a pilot randomized controlled trial. Annals of ... feature tracking and tissue tracking in ST-segment elevation myocardial infarction. The International Journal of Cardiovascular ... Remote ischemic preconditioning in the management of intermittent claudication: a pilot randomized controlled trial ... feature tracking and tissue tracking in ST-segment elevation myocardial infarction ...
cell differentiation | Leaders in Pharmaceutical Business Intelligence (LPBI) Group
In a mouse model of myocardial ischemia-reperfusion injury (IRI), S1P and its carrier, HDL, can help protect myocardial tissue ... As with preconditioning, SphK1 deficiency also affects post-conditioning of mouse hearts after ischemia reperfusion (IR). ... It seems they reduce cardiomyocyte apoptosis and neutrophil recruitment to the ischemic tissue and may decrease leukocyte ... SphK1 knockout mice cannot be preconditioned against IRI, whereas SphK1 gene induction in the heart protects it from IRI. ...
January | 2021 | Anti cancers | Page 2
"Background: The aim of this study was to investigate the effects of ischemic preconditioning (IPC) and N-acetylcysteine (NAC) ... In total, 459 (38.8%) patients were admitted for ST-elevation myocardial infarction (STEMI) and 724 (61.2%) for non-ST- ... Subjects in the preconditioning group were subjected to temporary ischemia, with tourniquet performed by three compression ... "Childhood ischemic strokes can lead to problems like hemiplegias, epilepsies, cognitive changes (memory and mathematical ...
OOIR: Observatory of International Research
Role of adiponectin in diabetes myocardial ischemia-reperfusion injury and ischemic postconditioning. 8. ... Preconditioning with L-Ala-Gln reduces the expression of inflammatory markers (TNF-α, NF-κB, IL-6 and HO-1) in an injury animal ... Naringin attenuates acute myocardial ischemia-reperfusion injury via miR- 126/GSK-3β/β-catenin signaling pathway. 4. ... GDF11 ameliorated myocardial ischemia reperfusion injury by antioxidant stress and up-regulating autophagy in STZ-induced type ...
Wyniki wyszukiwania
Tytu angielski: Ischemic preconditioning of heart vs sulphonylurea derivatives in treatment of diabetes.. Czasopismo: Pol. Prz ... Tytu angielski: Dobutamine stress echocardiography as a diagnostic tool in patients with myocardial bridges.. Czasopismo: Pol. ... Tytu angielski: Functional polymorphisms G-765C and T8473C of the cyclooxygenase-2 gene and the risk of myocardial infarction ... Tytu angielski: Electrocardiogram in risk stratification in patients with acute myocardial infarction.. Czasopismo: Pol. Prz. ...
Posts by Zhe Zheng, M.D., Ph.D.
Content Posted in 2018 | MaineHealth Knowledge Connection | MaineHealth Research
Effects of remote ischemic preconditioning in high-risk patients undergoing cardiac surgery (Remote IMPACT): a randomized ... Stroke and myocardial infarction following bronchial artery embolization in a cystic fibrosis patient., Matt Hoffman, Joseph P ... Pioglitazone prevents stroke in patients with a recent transient ischemic attack or ischemic stroke: a planned secondary ... Effects of pioglitazone on cognitive function in patients with a recent ischaemic stroke or TIA: a report from the IRIS trial. ...
The Second Affiliated Hospital Zhejiang University
A Large-Scale Investigation of Hypoxia-Preconditioned Allogeneic Mesenchymal Stem Cells for Myocardial Repair in Non-Human ... Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy. Cardiovascular Research. 2016;112: ... Zhu J, Lu K, Zhang N, Zhao Y, Ma Q, Shen J, Lin Y, Xiang P, Tang Y, Hu X, Chen J, Zhu W, Webster KA, Wang J, Yu H*. Myocardial ... Shearer GC, Chen J, Chen Y, Harris WS*. Myocardial infarction does not affect fatty-acid profiles in rats. Prostaglandins, ...
Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrel neural progenitor cells | eLife
2017) Neural stem cell transplantation in ischemic stroke: a role for preconditioning and cellular engineering Journal of ... 2016) Proteomic profiling reveals adaptive responses to surgical myocardial Ischemia-Reperfusion in hibernating arctic ground ... is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and ... Hibernating ground squirrels are resistant to ischemic and reperfusion injuries in numerous models, including brain and heart ...
Βιογραφικό | endocrineglandsurgery.net
Comparative Effects of Ischemic Preconditioning and Iron Chelation in Hepatectomy. Journal of investigative surgery : the ... Early myocardial injury is an integral component of experimental acute liver failure - A study in two porcine models. Archives ... Beyond Preconditioning: Postconditioning as an Alternative Technique in the Prevention of Liver Ischemia-Reperfusion Injury. ... Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ...
Bevillinger fra OUH's pulje med frie midler
The effect of short cycles of remote ischemic preconditioning (RIPC) on intestinal anastomotic healing: an animal experimental ... Development of risk assessment tools for identification of cardiogenic shock among patients with myocardial in-farction. A ... Screening and managing depression and anxiety with therapist-assisted eHealth intervention in patients with ischemic heart ... Screening and managing depression and anxiety with therapist-assisted eHealth intervention in patients with ischemic heart ...
Cell surface engineering and application in cell delivery to heart diseases | Journal of Biological Engineering | Full Text
... systemic injection of MSCs on rat myocardial infarction (MI) models revealed less than 1% accumulation of MSCs in the ischemic ... Liu H, Xue W, Ge G, Luo X, Li Y, Xiang H, Ding X, Tian P, Tian X. Hypoxic preconditioning advances CXCR4 and CXCR7 expression ... At the ischemic sites, MSCs can secrete arteriogenic cytokines, such as vascular endothelial growth factor (VEGF), basic ... Immediately after myocardial infarction, injured cardiomyocytes up-regulate SDF-1 expression to recruit stem cells for repair [ ...
HOMING Archives - ISSCA™. International Society for Stem Cells Applications
Myocardial infarction. The VLA-4/VCAM receptor axis has been shown to be involved in MSC migration in myocardial infarction. ... 74] found that i.v. MSCs localize to ischemic zones and deliver neurotrophic factors. This occurs at an increased rate when ... Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after ... Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti- ...
Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells - Stem Cells Lab
Myocardial infarction. The VLA-4/VCAM receptor axis has been shown to be involved in MSC migration in myocardial infarction. ... 74] found that i.v. MSCs localize to ischemic zones and deliver neurotrophic factors. This occurs at an increased rate when ... Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after ... Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti- ...
JCI - Volume 93, Issue 5
The coronary artery was occluded four times for 5 min separated by 5 min of reperfusion (ischemic preconditioning) in 82 dogs. ... whereas myocardial glucose uptake per muscle mass is reduced possibly due to decreased wall stress and energy requirements or ... Infarct size normalized by risk area was smaller after ischemic preconditioning than in the control group (40.6 +/- 2.3 vs 6.7 ... We have reported that ischemic preconditioning may limit infarct size by increasing 5-nucleotidase activity. The present study ...
Protection of the heart at a distance | ScienceDaily
STAT5 Activation and Cardioprotection by Remote Ischemic Preconditioning in Humans. Circulation Research, November 23, 2011 DOI ... In a myocardial infarction, parts of the cardiac muscle receive no blood supply because the coronary vessels are occluded. ... STAT signals improve the function of mitochondria, i.e. the cellular powerplants, and reduce the size of a myocardial ... Cardiovascular disease is the most frequent cause of death in Germany, and 70.000 people annually die from myocardial ...
Neuroprotection - Methods, Drugs, Markets and Companies
Figure 3-3: Pathomechanism of ischemic stroke and neuroprotective strategies. Figure 3-4: Molecules involved in preconditioning ... Neuroprotection after myocardial infarction. *Neuroprotection in hypertensive encephalopathy. *Management of hypertension to ... Figure 1-1: A three-stage model of ischemic hypoxic disturbances of the brain. Figure 2-1: Mechanism of neuroprotective effect ... for the treatment of ischemic stroke in experimental models. Table 3-4: Neuroprotective gene transfer in models of cerebral ...
Rules of Procedure | About-us
Impact of ischemic preconditioning on the radial artery vasomotor function. Eduardo Arroyo-Úcar, Borja Ibáñez Cabeza, et al. ... Quantitative flow ratio in myocardial infarction for the evaluation of non-infarct-related arteries. The QIMERA pilot study ... Considerations on the invasive management of ischemic and structural heart disease during the COVID-19 coronavirus outbreak. ...
Ischemia - Myocardial Infarction | CU Experts | CU Boulder
Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart Journal Article ... Injectable Shear-Thinning Hydrogels Prevent Ischemic Mitral Regurgitation and Normalize Ventricular Flow Dynamics Journal ... Ischemia - Myocardial Infarction PubMed MeSh Term *Overview. Overview. subject area of * A novel genetic marker of decreased ... IMPAIRED CARDIAC-FUNCTION IN RATS WITH HEALED MYOCARDIAL-INFARCTION - CELLULAR VS MYOCARDIAL MECHANISMS Journal Article ...
Browse Cochrane - Essential Evidence Plus
Remote ischaemic preconditioning versus no remote ischaemic preconditioning for vascular and endovascular surgical procedures ... Dan Shen agents for acute ischaemic stroke , 18-Apr-07. *. Danshen (Chinese medicinal herb) preparations for acute myocardial ... Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed ... Anticoagulants for preventing recurrence following presumed non‐cardioembolic ischaemic stroke or transient ischaemic attack , ...
oalib
The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia- ... Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced ... New determinants for casual peripheral mechanism of neurogenic lung edema in subarachnoid hemorrhage due to ischemic ...
A unique pathway of cardiac myocyte death caused by hypoxia-acidosis | Journal of Experimental Biology | The Company of...
The condition parallels myocardial ischemia in vivo, where ischemic tissue becomes rapidly hypoxic and acidotic. Cardiac ... Myocardial ischemia and infarction: anatomic and biochemical substrates for ischemic cell death and ventricular arrhythmias. ... Modes of myocardial cell injury and cell death in ischemic heart disease. Circulation ... Loss of cardiac myocytes is a central feature of heart disease of both ischemic and non-ischemic origin (reviewed in Anversa ...
Clinical Trials in Cardiology | Open Access Journal | Editorial Board
He has published seminal papers in the field of cardioprotection, especially in the ischemic preconditioning, gene cell therapy ... These models include, but are not limited to, Transverse aortic constriction, Myocardial infarction, Myocardial Ischemia/ ... Elucidating the Mechanisms of Ischemic-Pharmacologic and Exercise-Induced Preconditioning by Using the Ischemia/Reperfusion in ... Myocardial Infarction, Myocardial Ischemia/Reperfusion injury, Heart Failure, Limb Ischemia, Middle Cerebral Artery Occlusion ( ...
RhoA Pull-down Activation Assay - Cytoskeleton, Inc.
Laboratoire sur l'étude des accidents vasculaires cérébraux et du recouvrement comportemental
Plamondon H, Davignon G, Khan S & Charron C (2008). Cerebral ischemic preconditioning induces lasting effects on CA1 neuronal ... Poitras M, Narvaez Linares NF, Lambert M, Browndyke JN & Plamondon H (2022). Women with Myocardial Infarction Present Subtle ... Endogenous fluctuations in Leu-enkephalin opioid peptides associated with global cerebral ischemia and ischemic preconditioning ... Plamondon H & Roberge MC (2008). Dietary PUFA supplements reduce memory deficits but not CA1 ischemic injury in rats. ...
Cell Cycle - TAM Receptor Signaling in Immune Homeostasis
1. Intro Curbing myocardial redesigning after AMI remains a Delamanid biological activity major challenge [1, 2]. Stem cell ... treatment against ischemic accidents. Many molecular and mobile mechanisms fundamental the defensive ramifications of hypoxic ... preconditioning have already been discovered. Conclusions: In cell transplantation therapy, hypoxic pretreatment of stem cells ... could be induced by surprise wave treatment in the peripheral bloodstream to ischemic hind limbs.[45] In chronic hypoxia extra ...
Beating heart coronary surgery supported by an axial blood flow pump / Медикус. Посольство медицины
An increase in myocardial perfusion pressure and decrease in myocardial oxygen consumption during HP treatment of experimental ... The patients in the control group were operated on using CPB and aortic cross-clamping with cold ischemic arrest. Those in the ... creating a global left ventricular preconditioning. ... and myocardial trauma as measured by postoperative troponin-T ... Myocardial revascularization with the left internal thoracic artery Y graft configuration Myocardial revascularization with the ...
Gels - Toll-like receptor 4