Iron-binding proteins - Wikipedia
Iron Iron-binding+proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Brock JH (1989). "Iron- ... Iron-binding proteins are carrier proteins and metalloproteins that are important in iron metabolism and the immune response. ... De Sousa M, Breedvelt F, Dynesius-Trentham R, Trentham D, Lum J (1988). "Iron, iron-binding proteins and immune system cells". ... Iron-sulfur proteins are those with an iron structure that includes sulfur. There are a variety of forms iron and sulfur can ...
Sre1, an iron-modulated GATA DNA-binding protein of iron-uptake genes in the fungal pathogen Histoplasma capsulatum
Because iron is toxic at high levels, iron acquisition in pathogenic organisms, including H. capsulatum, is a highly regulated ... In response to excess iron, H. capsulatum represses transcr … ... The pathogenic fungus Histoplasma capsulatum requires iron for ... Sre1, an iron-modulated GATA DNA-binding protein of iron-uptake genes in the fungal pathogen Histoplasma capsulatum ... Sre1p specifically bound DNA containing the 5-(G/A)ATC(T/A)GATAA-3 sequence, and that binding was both iron- and zinc- ...
Influence of Cupric (Cu<sup>2+</sup>) Ions on the Iron Oxidation Mechanism by DNA-Binding Protein from Starved Cells (Dps) from...
Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the Ferritin family ... N2 - Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the Ferritin ... AB - Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the Ferritin ... abstract = "Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the ...
Serum Protein-Resistant Behavior of Multisite-Bound Poly(ethylene glycol) Chains on Iron Oxide Surfaces
... Giamblanco N;MARLETTA ... To this aim, we use a non-covalent grafting-to method to functionalize iron oxide sub-10 nm nanoparticles and iron oxide flat ... To this aim, we use a non-covalent grafting-to method to functionalize iron oxide sub-10 nm nanoparticles and iron oxide flat ... In this study, we address the issue of the interactions of plasma proteins with polymer coated surfaces. ...
Cellular contamination pathway for plutonium, other heavy elements, identified | ScienceDaily
Scientists find that an iron-binding protein can transport actinides into cells. Date:. August 26, 2015. Source:. DOE/Lawrence ... including characterization of the first ever protein structures containing transuranic elements and how use of the protein can ... "Until this work there was no structure in the Protein Data Bank that had those elements. Thats an exciting thing for us." ... "We showed that this protein is capable of transporting plutonium inside cells," she said. "So this could help us develop other ...
MMP0198 MMP0198 ABC-type iron(III) transport system, ATP binding protein (NCBI) | Syntrophy Portal
Protein Synonyms Start End Strand PubMed ID MMP0198 MMP0198 MMP0198 MMP0198 ABC-type iron(III) transport system, ATP binding ... MMP0198 MMP0198 ABC-type iron(III) transport system, ATP binding protein (NCBI). × Error message. *Unable to create CTools CSS ... Protein families (PH) COG1120 , ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components (3.6.3.34) Iron- ... NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG Q6M0S1 2762542 NP_987318.1; 45357761 532385 CAF29754 ...
MexAM1 META1p5270 6830060 protochlorophyllide reductase iron-sulfur ATP-binding protein BchL (RefSeq) | Syntrophy Portal
1o7t.3 | SWISS-MODEL Template Library
Metal nanoclusters bound to the Ferric Binding Protein from Neisseria gonorrhoeae. ... IRON BINDING PROTEIN: A. SMTL:PDB. SMTL Chain Id:. PDB Chain Id:. A. C ... Metal nanoclusters bound to the Ferric Binding Protein from Neisseria gonorrhoeae. Coordinates. PDB Format Method. X-RAY ... Alexeev, D. et al., A novel protein-mineral interface. Nat. Struct. Biol. (2003) Release Date. 2003-02-27. Peptides. ...
Vitreous Hemorrhage: Background, Pathophysiology, Epidemiology
... the catabolism of hemoglobin can take place extracellularly and the released iron binds to vitreous proteins with iron-binding ... Iron-binding proteins in vitreous humour. Biochim Biophys Acta. 1983 Jul 5. 758(1):17-23. [QxMD MEDLINE Link]. ... The vitreous contains 13 times more iron-binding proteins relative to the serum, with a physiological saturation of the total ... Inflammation-induced changes in the iron concentration and total iron- binding capacity of the intraocular fluids of rabbits. ...
Page 1 | Search Results | Acta Haematologica | Karger Publishers
Open the PDF for Levels of Iron, Vitamin B 12 , Folic Acid and Their Binding Proteins during Pregnancy in another window ... Levels of Iron, Vitamin B 12 , Folic Acid and Their Binding Proteins during Pregnancy ... View article titled, Levels of Iron, Vitamin B 12 , Folic Acid and Their Binding Proteins during Pregnancy ...
Iron-Ferrying Protein Impedes Pathogens | The Scientist Magazine®
Meningitis-causing bacteria exerted strong evolutionary pressure on an iron-binding protein in primates, a study shows. ... Iron-Ferrying Protein Impedes Pathogens. Meningitis-causing bacteria exerted strong evolutionary pressure on an iron-binding ... In primates, the iron-carrying protein transferrin likely evolved to inhibit meningitis-causing bacteria from scavenging iron, ... and found remarkable variation at sites known to interact with a bacterial transferrin binding protein, TbpA. Two bacterial ...
Association of spinal degenerative disc disease with thyroid autoimmunity
Mass Die-Off of Saiga Antelopes, Kazakhstan, 2015 - Volume 25, Number 6-June 2019 - Emerging Infectious Diseases journal - CDC
WP_010906625], iron ABC transporter substrate binding protein [accession no. WP_005715971.1], iron binding protein [accession ... For example, proteins facilitating active iron uptake (iron ABC transporter permease [GenBank accession no. ... WP_005726096.1], and iron permease [accession no. WP_010906655.1]) or proteins of the oxidative stress response (catalase [ ... Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, et al. Gapped BLAST and PSI-BLAST: a new generation of protein ...
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Methemoglobinemia, beta-globin type: MedlinePlus Genetics
Each of these protein subunits is bound to an iron-containing molecule called heme. ; each heme contains an iron molecule in ... For hemoglobin to bind to oxygen, the iron within the heme molecule needs to be in a form called ferrous iron (Fe2+). The iron ... The ferric iron cannot bind oxygen and causes cyanosis and the brown appearance of blood. ... within the heme can change to another form of iron called ferric iron (Fe3+), which cannot bind oxygen. Hemoglobin that ...
Staff Profile - Centre for Bacterial Cell Biology - Newcastle University
A periplasmic iron-binding protein contributes toward inward copper supply. Journal of Biological Chemistry 2007, 282(6), 3837- ... Protein-folding location can regulate manganese-binding versus copper- or zinc-binding. Nature 2008, 455(7216), 1138-1142. ... Badarau A, Firbank SJ, Waldron KJ, Yanagisawa S, Robinson NJ, Banfield MJ, Dennison C. FutA2 is a ferric binding protein from ... Basic requirements for a metal-binding site in a protein: The influence of loop shortening on the cupredoxin azurin. ...
4RAS: Reductive Dehalogenase Structure Suggests A Mechanism For B12- Dependent Dehalogenation
SCOPe 2.08: Structural Classification of Proteins - extended
... and ASTRAL compendium for protein structure and sequence analysis ... Keywords: DpsA, ferritin, low-iron, METAL BINDING PROTEIN. ... Structural analysis of H.salinarum DpsA in its low and high iron states. Class: metal binding protein. ... Compound: Iron-rich dpsA-homolog protein. Species: Halobacterium salinarum [TaxId:2242]. Database cross-references and ... Compound: Iron-rich dpsA-homolog protein. Species: Halobacterium salinarum [TaxId:2242]. Database cross-references and ...
SCOPe 2.08: Structural Classification of Proteins - extended
... and ASTRAL compendium for protein structure and sequence analysis ... Keywords: iron binding protein, lactoferrin, antibacterial, ... Compound: protein (lactoferrin). Species: Bubalus bubalis [TaxId:89462]. Database cross-references and differences (RAF-indexed ... SCOPe: Structural Classification of Proteins - extended. Release 2.08 (updated 2023-01-06, stable release September 2021) ...
Publication Detail
Iron-Binding Proteins/blood*; Iron-Binding Proteins/chemistry; Iron-Binding Proteins/genetics; Mitochondria/metabolism; Protein ... is a critically important protein because it facilitates the assembly of mitochondrial iron-sulfur cluster protein complexes ... Abstract: Frataxin is a highly conserved protein encoded by the frataxin (FXN) gene. The full-length 210-amino acid form of ... Decreased expression of frataxin protein is responsible for the devastating rare genetic disease of Friedreich's ataxia. ...
Thieme E-Journals - Ernährung & Medizin / Abstract
Identification of the serum binding proteins of iron, zinc, cadmium nickel, and calcium. Clin Chem 1983; 29: 629-633 ... Iron concentrations in atherosclerotic plaque and serum in patients with carotid atherosclerosis. Acta Physiol Hung 2015; 102: ... Cytokine production and serum proteins in depression. Scand J Immunol 1995; 41: 534-538 ...
Turano Paola | Scheda personale | Università degli Studi di Firenze | UniFI
Ciambellotti, Silvia; Turano, Paola (2019). Structural Biology of Iron-Binding Proteins by NMR Spectroscopy. EUROPEAN JOURNAL ... NMR as a tool to target protein-protein interactions. In: Stefano Mangani. Disruption of Protein-Protein Interfaces. In Search ... A Relay Network of Extracellular Heme-Binding Proteins Drives C. albicans Iron Acquisition from Hemoglobin. PLOS PATHOGENS, vol ... Ciambellotti S.; Pratesi A.; Tassone G.; Turano P.; Mangani S.; Pozzi C. (2021). Iron Binding in the Ferroxidase Site of Human ...
Aco1 MGI Mouse Gene Detail - MGI:87879 - aconitase 1
IPR006249 Aconitase/Iron-responsive element-binding protein 2. IPR036008 Aconitase, iron-sulfur domain ... J:335117 Bonadonna M, et al., Iron regulatory protein (IRP)-mediated iron homeostasis is critical for neutrophil development ... protein coding gene. Chr4:40143081-40199009 (+). 129S1/SvImJ MGP_129S1SvImJ_G0028140. protein coding gene. Chr4:37979830- ... protein coding gene. Chr4:34270353-34328873 (+). CAST/EiJ MGP_CASTEiJ_G0027294. protein coding gene. Chr4:37712961-37774155 (+) ...
Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation | Nature Structural &...
The essential ATP-binding cassette protein ABCE1 splits 80S ribosomes into 60S and 40S subunits after canonical termination or ... Compared to the pre-splitting state, we observe repositioning of ABCE1s iron-sulfur cluster domain, which rotates 150° into a ... binding pocket on the 40S subunit. This repositioning explains a newly observed anti-association activity of ABCE1. Notably, ... Cryo-EM structures of the yeast 40S in complex with ribosome-splitting protein ABCE1, along with functional analyses, reveal ...
Volume 74 Issue 2 | Acta Haematologica | Karger Publishers
Lee M. Wetzler, M.D. | Virology, Immunology & Microbiology
Pharmaceutics | Free Full-Text | Candida glabrata Antifungal Resistance and Virulence Factors, a Perfect Pathogenic Combination
... glabrata can acquire free iron and iron from iron-binding proteins such as hemoglobin, ferritin, and transferrin. The ... are the main cell surface proteins involved in C. glabrata virulence [65,154,160]. Epa proteins are analogous to Als proteins ... Moreover, certain proteins have been identified in C. glabrata, such as Pwp7p and Aed1p, that are relevant for adherence in ... Genes and Proteins Involved. Mechanisms Involved. Result. Complex C. glabrata. Azoles. Multiple drugs. Mutations (polymorphisms ...
Neurotoxins: Definition, Epidemiology, Etiology
Furthermore, carbon monoxide binds to other iron-containing proteins such as myoglobin, cytochrome p450, catalase, peroxidase, ... Carbon monoxide binds to hemoglobin, which has a 210-fold greater affinity for carbon monoxide than for oxygen. [7] This ... Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening ... Both carbon disulfide and n-hexane are thought to cause toxicity by crosslinking proteins, including neurofilaments. [14] ...
Extracellular heme recycling and sharing across species by novel mycomembrane vesicles of a Gram-positive bacterium | The ISME...
... we found that under iron-limiting conditions, heme-binding proteins are enriched. Next, we proved that MVs participate in ... When comparing proteomes of MVs between iron-limiting and iron-rich conditions, ... DQ12-45-1b, to analyze the function of its MVs in heme-iron recycling and sharing between species. We determined the structure ... However, whether MVs are also responsible for efficient iron uptake and therefore involved in microbial interaction remains to ...