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ras GTPase-Activating Proteinscdc42 GTP-Binding Proteinrac1 GTP-Binding ProteinProtein BindingCalmodulinActinsCytoskeletonCarrier ProteinsGTPase-Activating ProteinsGlutathione TransferaseWiskott-Aldrich Syndrome Protein, NeuronalProtein Interaction Domains and MotifsProtein Structure, TertiaryCytoskeletal ProteinsCell Movementrac GTP-Binding ProteinsCadherinsSignal TransductionMAP Kinase Kinase 2Actin-Related Protein 3CytokinesisGTP PhosphohydrolasesActin-Related Protein 2RNA, Small InterferingAntidiarrhealsCell Polaritybeta CateninImmunoprecipitationGuanosine TriphosphateCell Line, TumorGTP-Binding Proteinsalpha CateninCarcinoma, Papillary, FollicularAdherens JunctionsRecombinant Fusion ProteinsActin CytoskeletonrhoB GTP-Binding ProteinProto-Oncogene Proteins B-rafIntercellular JunctionsErythema MultiformeModels, BiologicalCOS CellsHEK293 CellsPlasmidsInverted Repeat Sequencesrho GTP-Binding ProteinsMicrofilament ProteinsProtein TransportGreen Fluorescent ProteinsMicroscopy, FluorescenceRNA InterferenceCell Cycle ProteinsPrecipitin TestsMolecular Sequence DataPhosphorylationrhoA GTP-Binding ProteinCells, CulturedBlotting, WesternAmino Acid SequenceAmino Acid MotifsMAP Kinase Signaling SystemMice, 129 StrainCercopithecus aethiopsMicrotubule-Associated ProteinsPseudopodiaTransfectionProtein Interaction MappingMAP Kinase Kinase 1Parietal Cells, GastricFilaminsCell LineMicrotubulesPenetrancep21-Activated KinasesReceptor-Like Protein Tyrosine Phosphatases, Class 2NIH 3T3 CellsMutant ProteinsRecombinant Proteinscdc42 GTP-Binding Protein, Saccharomyces cerevisiaeActininWiskott-Aldrich Syndrome ProteinCell Membranerap1 GTP-Binding ProteinsSalmonella InfectionsFluorescent Antibody Technique, DirectMutationCell AdhesionGene Expression Regulation, NeoplasticAcyl-ButyrolactonesSequence Homology, Amino AcidBinding SitesGuanosine 5'-O-(3-Thiotriphosphate)Protein Kinase C-epsilonMice, KnockoutImmunohistochemistryProstatic Intraepithelial NeoplasiaCell ProliferationProteomicsDendritic SpinesProtein Prenylation
IQGAP1 - WikipediaIQGAP1 - Wikipedia
IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. IQGAP1 is a ... IQGAP1 does bind Rho GTPases CDC42 and RAC1, however, IQGAP1 is unusual in that it actually has no GAP function, and instead ... IQGAP1 has 5 well-known domains separated by other amino acids. Starting at the N-terminus (or front of the protein), IQGAP1 ... IQGAP1 seems to be responsible for the specific output of the pathway upon activation by EGF. IQGAP1 plays a significant role ...
https://en.wikipedia.org/wiki/IQGAP1
Anti-IQGAP1 Rabbit Polyclonal Antibody | VWRAnti-IQGAP1 Rabbit Polyclonal Antibody | VWR
Antigen: IQGAP1. Clonality: Polyclonal. Clone: Conjugation: Unconjugated. Epitope: Host: Rabbit. Isotype: IgG. Reactivity: ...
https://us.vwr.com/store/product/14057639/anti-iqgap1-rabbit-polyclonal-antibody
IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation |...
IQGAP1 expression was decreased in ovarian CSC-LCs compared with parental 3AO cells, but increased de novo during the ... Conclusions Increased IQGAP1 expression during the differentiation of CSC-LCs is involved in an aggressive cell behavior, which ... IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation ... Knockdown of IQGAP1 by specific small interfering RNA remarkably weakened invasion capacity of 2-day differentiated ovarian CSC ...
https://ijgc.bmj.com/content/25/4/559
MMRRC:040067-MUMMRRC:040067-MU
Iqgap1. Name: IQ motif containing GTPase activating protein 1. Synonyms: D7Ertd237e, D7Ertd257e ...
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=40067
VEGF - VEGF R2 Signaling Pathways: R&D SystemsVEGF - VEGF R2 Signaling Pathways: R&D Systems
IQGAP1. ProductsClose. PI 3-Kinase p55 gamma. PI 3-Kinase p85 alpha. PI 3-Kinase p85 beta. PI 3-Kinase p110 beta. PI 3-Kinase ...
https://www.rndsystems.com/cn/pathways/vegf-vegf-r2-signaling-pathways
Monica S Thakar, MDMonica S Thakar, MD
IQGAP1: insights into the function of a molecular puppeteer.. 25733387 Molecular immunology, 2015 June : 65(2)336-49 PMCID: ... IQGAP1: a regulator of intracellular spacetime relativity.. 22345702 Journal of immunology (Baltimore, Md. : 1950), 2012 Mar 1 ...
https://www.seattlechildrens.org/directory/monica-s-thakar/
Regulation of actin cytoskeleton (WP523) - Mus musculus | WikiPathwaysRegulation of actin cytoskeleton (WP523) - Mus musculus | WikiPathways
Iqgap1. GeneProduct. ncbigene:29875. Vcl. GeneProduct. ncbigene:22330. Fgf10. GeneProduct. ncbigene:14165. ...
https://www.wikipathways.org/pathways/WP523.html
CLINICAL GENE SIGNATURE-BASED HUMAN CELL CULTURE MODEL AND USES THEREOF - UNIV STRASBOURGCLINICAL GENE SIGNATURE-BASED HUMAN CELL CULTURE MODEL AND USES THEREOF - UNIV STRASBOURG
IQGAP1, NOL7, RBM34, NFKB2, COL16A1, AP1B1, IFI3, and ABLIM1. ...
https://www.sumobrain.com/patents/wipo/Clinical-gene-signature-based-human/WO2016174130A1.html
NRDC Antibody - middle region (ARP58755 P050) | Aviva Systems Biology | Avivasysbio.comNRDC Antibody - middle region (ARP58755 P050) | Aviva Systems Biology | Avivasysbio.com
Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma | eLifeSpatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma | eLife
Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1 Huan Fang, ... In this study, we found that TNFAIP2 interacts with IQGAP1 and Integrin β4. Integrin β4 activates RAC1 through TNFAIP2 and ... Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1 ... These results indicate that the Integrin β4/TNFAIP2/IQGAP1/RAC1 axis provides potential therapeutic targets to overcome DNA ...
https://elifesciences.org/articles/86125
David B. Sacks, MB ChB, FACP, FRCPath | Clinical CenterDavid B. Sacks, MB ChB, FACP, FRCPath | Clinical Center
IQGAP1 binds to Yes-associated protein (YAP) and modulates its transcriptional activity. J Biol Chem 2016; 291:19261-19273. ... IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration. EMBO J 2013; 32: ... MAP kinase scaffold IQGAP1 binds the EGF receptor and modulates its activation. J Biol Chem 2011; 286:15010-15021. ... IQGAP1 stimulates proliferation and enhances tumourigenesis of human breast epithelial cells. J Biol Chem 2008; 283:1008-1017. ...
https://clinicalcenter.nih.gov/meet-our-doctors/dsacks.html
GEO Accession viewerGEO Accession viewer
IQGAP1 serves a role in erlotinib-related purpuric dermatitis. GSE87028. In vitro effect of liver carcinogens aflatoxin B1 and ...
https://ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL16699
SMART: IQ domain annotationSMART: IQ domain annotation
Ras GTPase-activating-like protein IQGAP1. IQGAP1 contains 4 IQ motifs.. This entry covers the entire IQ motif. ...
https://smart.embl.de/smart/do_annotation.pl?DOMAIN=IQ&START=765&END=787&E_VALUE=3.65e-4&TYPE=SMART&BLAST=KLRAACIRIQKTIRGWLLRKRYL
Richard L. Huganir - PublicationsRichard L. Huganir - Publications
Phosphorylation-dependent interactions of alpha-Actinin-1/IQGAP1 with the AMPA receptor subunit GluR4. Journal of ...
https://neurotree.org/beta/publications.php?pid=1273
U0126 (CAS 109511-58-2): R&D SystemsU0126 (CAS 109511-58-2): R&D Systems
ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1. Authors: Sbroggi&# ...
https://www.rndsystems.com/cn/products/u0126_1144
Recombinant Human Wnt-3a Protein (5036-WN): Novus BiologicalsRecombinant Human Wnt-3a Protein (5036-WN): Novus Biologicals
Carmon K, Gong X, Yi J, Thomas A, Liu Q RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Proc Natl Acad Sci U S A, ... Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H IQGAP1 protein regulates nuclear localization of beta-catenin via ...
https://www.novusbio.com/products/recombinant-human-wnt-3a-protein_5036-wn
Reactome | UniProt:Q12905 ILF2Reactome | UniProt:Q12905 ILF2
IQGAP1 [plasma membrane] (R-HSA-381681) 0.556. 3 Q9NRD5 2 * PICK1 [endocytic vesicle membrane] (R-HSA-417017) ...
https://reactome.org/content/detail/interactor/Q12905
Reactome | UniProt:Q96N21 AP4ATReactome | UniProt:Q96N21 AP4AT
IQGAP1 [plasma membrane] (R-HSA-381681) 0.556. 3 P55081 1 * MFAP1 [nucleoplasm] (R-HSA-2396419) ...
https://www.reactome.org/content/detail/interactor/Q96N21
Zhouxiang Jins Research on IQ motif containing GTPase activating protein 1 | CureHunterZhouxiang Jin's Research on IQ motif containing GTPase activating protein 1 | CureHunter
IQGAP1 plays an important role in the cell proliferation of multiple myeloma via the MAP kinase (ERK) pathway.. ...
https://www.curehunter.com/public/authorSummary-Jin,%20Zhouxiang.do?keywordId=C101203
P-ARRESTIN REGULATES LYSOPHOSPHATIDIC ACID-INDUCED HUMAN BREAST CANCER by Mistre Alemayehu"P-ARRESTIN REGULATES LYSOPHOSPHATIDIC ACID-INDUCED HUMAN BREAST CANCER" by Mistre Alemayehu
Additionally, P-arrestin2 and IQGAP1 associate in response to LPA and IQGAP1 knockdown blocks breast cancer invasion. Thus, our ... data suggests a novel mechanism by which LPA regulates breast cancer cell invasiveness via Rapl, P-arrestin2, and IQGAP1. ... We found that Rapl interacts with the multi-functional scaffolding proteins P-arrestin2 and IQGAP1 that are critical regulators ... Additionally, P-arrestin2 and IQGAP1 associate in response to LPA and IQGAP1 knockdown blocks breast cancer invasion. Thus, our ...
https://ir.lib.uwo.ca/digitizedtheses/3720/
S100B Elisa - Antibody and Protein Microarrays Chips qPCR Array and PCR Array for cell signaling
Description: Description of target: S100b binds GTPase activating protein IQGAP1; It may play a role in cell membrane ... Description: Description of target: binds GTPase activating protein IQGAP1; may play a role in cell membrane rearrangement [RGD ...
https://www.microarraystation.com/s100b-elisa-2/
Page 18Page 18
KISS1R Induces Human Mammary Epithelial Cell Invasiveness and Promotes Breast Cancer Cell Migration and Invasion via IQGAP1, ...
https://ir.lib.uwo.ca/etd/index.18.html
Paul A. Khavari, MD, PhDs Profile | Stanford ProfilesPaul A. Khavari, MD, PhD's Profile | Stanford Profiles
IQGAP1, an ERK1/2 MAPK scaffold, is an oncogenic target in canine melanoma Zehnder, A., Lee, B., Neela, P., Khavari, P. AMER ...
https://profiles.stanford.edu/paul-khavari
Polyclonal Antibodies Online Page 767 - CusabioPolyclonal Antibodies Online Page 767 - Cusabio
IQGAP1 Antibody. CSB-PA003059. Human,Mouse. WB, ELISA. 100μg/50μg. ...
https://www.cusabio.com/catalog-20-767.html
NamespaceNamespace
GPR IQGAP1,GPR IQGAP2,GPR IQGAP3,GPR IQSEC1,GPR IQSEC2,GPR IQSEC3,GPR IQSEC3P1,G IQSEC3P2,G IQSEC3P3,G IQUB,GPR IRAIN,GR IRAK1, ...
https://raw.githubusercontent.com/pharmacome/terminology/efc856fb009a39e4d284269a6801f79ed3d3cf56/external/hgnc-names.belns
The evolutionary history of effectors downstream of Cdc42 and Rac | Genome Biology | Full TextThe evolutionary history of effectors downstream of Cdc42 and Rac | Genome Biology | Full Text
IQGAP1 has been detected in a complex with filamentous actin and Cdc42, and has been shown to localize to cell-cell adhesion ...
https://genomebiology.biomedcentral.com/articles/10.1186/gb-2002-3-2-reviews0002
Find Research outputs - The University of Brighton
Effects of thymosin β4 on wound healing of rat palatal mucosaEffects of thymosin β4 on wound healing of rat palatal mucosa
Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction ...
https://www.spandidos-publications.com/10.3892/ijmm.2014.1832?text=fulltext
Gene Expression Profiles of B-lineage Adult Acute Lymphocytic Leukemia Reveal Genetic Patterns that Identify Lineage Derivation...Gene Expression Profiles of B-lineage Adult Acute Lymphocytic Leukemia Reveal Genetic Patterns that Identify Lineage Derivation...
IQGAP1, ADD3, TLN1, ITGB1, LGALS8, CAPZB, DNCI2, LSP1, and nexilin); (b) membrane antigens (CD79a, CD79b, CD24, CD45, CD62L, ...
https://aacrjournals.org/clincancerres/article-split/11/20/7209/188537/Gene-Expression-Profiles-of-B-lineage-Adult-Acute
RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data.RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data.
IQGAP1. P46940 DYNLL1-208. ENST00000550178 581 nt. BASIC. 43.37. ■■■■■ 4.53. IQGAP1. P46940 ANAPC11-203. ENST00000392376 687 nt ... IQGAP1. P46940 AL356512.1-201. ENST00000607453 1739 nt. BASIC. 47.29. ■■■■■ 5.16. IQGAP1. P46940 GALR3-201. ENST00000249041 ... IQGAP1. P46940 ZNRF2P1-201. ENST00000441407 443 nt. BASIC. 45.95. ■■■■■ 4.95. IQGAP1. P46940 AC006077.2-201. ENST00000623591 ... IQGAP1. P46940 AP002365.1-201. ENST00000603448 772 nt. BASIC. 44.96. ■■■■■ 4.79. IQGAP1. P46940 SEPT3-204. ENST00000406029 1866 ...
http://rnact.crg.eu/protein?query=P46940