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*  HCN4 - Wikipedia
Cyclic nucleotide-gated ion channel Funny current GRCh38: Ensembl release 89: ENSG00000138622 - Ensembl, May 2017 GRCm38: ... "Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated ... "Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and ... The role of HCN channels in autonomic control of heart rate is currently a matter of ongoing investigation. HCN4 has been shown ...
https://en.wikipedia.org/wiki/HCN4
*  Chloride channel - Wikipedia
Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many ... Chloride channels are also important for maintaining safe ion concentrations within plant cells. The CLC channel structure has ... For the channels, when the slow gate is closed, no ions permeate through the pore. When the slow gate is open, the fast gates ... In the channels, the protein does not shield chloride ions at one binding site from the neighboring negatively charged ...
https://en.wikipedia.org/wiki/Chloride_channel
*  TRPV1 - Wikipedia
This protein is a member of the TRPV group of transient receptor potential family of ion channels. The function of TRPV1 is ... The dorsal root ganglion (DRG) neurons of mammals were known to express a heat-sensitive ion channel that could be activated by ... a heat-activated ion channel in the pain pathway". Nature. 389 (6653): 816-24. doi:10.1038/39807. PMID 9349813. Xue Q, Yu Y, ... and CBDV are also agonists of this ion channel. TRPV1 is also expressed at high levels in the central nervous system and has ...
https://en.wikipedia.org/wiki/TRPV1
*  Inward-rectifier potassium channel - Wikipedia
In this regard Kir channels are PIP2 ligand-gated ion channels. Kir channels are found in multiple cell types, including ... IRK channels possess a pore domain, homologous to that of voltage-gated ion channels, and flanking transmembrane segments (TMSs ... "Inwardly Recifying Potassium Channels". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and ... Bertil Hille (2001). Ion Channels of Excitable Membranes 3rd ed. (Sinauer: Sunderland, MA), p. 151. ISBN 0-87893-321-2. Hille, ...
https://en.wikipedia.org/wiki/Inward-rectifier_potassium_channel
*  Ion Channels
... ions across the cell membrane are responsible for the rhythmic beating of heart cells. ... Channels that control the flow of potassium (K+) and sodium (Na+) ... called ion channels. Some valves let certain ions like potassium (K+) flow out, others let different ions like sodium (Na+) ... When a heart cell beats, sodium channels open allowing a rapid, transient in-rush of Na+ ions, then close within about two one- ...
https://www.cellsalive.com/channels.htm
*  Ion Channel Electrophysiology
The study of ion channels is called electrophysiology, and is described in this article. ... Ion channels are imperative to the normal functioning of the cell. ... Ion channels are proteins embedded in the cell membrane which control the bidirectional movement of charged species called ions ... Ion channels are highly selective and can be grouped according to their structure, either as members of the voltage-gated or ...
https://www.news-medical.net/life-sciences/Ion-Channel-Electrophysiology.aspx
*  Ion Channels and Ion Pumps | SpringerLink
Ion Channels and Ion Pumps. Metabolic and Endocrine Relationships in Biology and Clinical Medicine. ... Characterization of Ion Channels in the Central Nervous System: Insights from Radioligand Binding, Autoradiography, and In Situ ... Calcium Ion Homeostasis in the Aging Brain: Regulation of Voltage-Dependent Calcium Channels ... Interactions of Ethanol with Ion Channels: Possible Implications for Mechanisms of Intoxication and Dependence ...
https://link.springer.com/book/10.1007/978-1-4612-2596-6
*  Stem Cells and Ion Channels
Ion Flux Dependent and Independent Functions of Ion Channels in the Vertebrate Heart: Lessons Learned from Zebrafish, Mirjam ... Stem Cells and Ion Channels. Guest Editors: Stefan Liebau, Alexander Kleger, Michael Levin, and Shan Ping Yu *Stem Cells and ... Ion Channel Activities in Neural Stem Cells of the Neuroepithelium, Masayuki Yamashita Review Article (6 pages), Article ID ... Ion Channels in Hematopoietic and Mesenchymal Stem Cells, Serena Pillozzi and Andrea Becchetti Review Article (9 pages), ...
https://www.hindawi.com/journals/sci/si/192421/
*  ligand-gated ion channels
... chrissy chrissy_4u2c at hotmail.com Thu Oct 30 07:30:23 EST 2003 *Previous message: UV laser for DNA ... With a multisubunit ion channel, where the subunits have multiple transmembrane helices, how do you tell which of a subunit's ... And how does that relate to ligand-gated channels in general? *Previous message: UV laser for DNA-protein cross-linking ...
http://www.bio.net/bionet/mm/proteins/2003-October/011318.html
*  Ion channels in inflammation | SpringerLink
These disease processes can be explained by changes in numbers or function of ion channels. Changes in ion channels have been ... Suh B-C, Hille B (2008) PIP2 is a necessary cofactor for ion channel function: How and why? Annu Rev Biophys 37:175-195PubMed ... Yiangou Y, Facer P, Baecker PA, Ford AP, Knowles CH, Chan CL, Williams NS, Anand P (2001) ATP-gated ion channel P2X3 is ... Okuse K (2007) Pain signalling pathways: From cytokines to ion channels. Internat J Biochem Cell Biol 39:490-496Google Scholar ...
https://link.springer.com/article/10.1007%2Fs00424-010-0917-y
*  Ion Channels/Membrane Transport | Circulation
... and Therapeutic Approaches for Primary Cardiomyopathies of Gene Mutations Affecting Ion Channel Function Stephan E. Lehnart, ... Direct Inhibition of Cardiac Hyperpolarization-Activated Cyclic Nucleotide-Gated Pacemaker Channels by Clonidine Anne Knaus, ... Channels Tian Xue, Chung-Wah Siu, Deborah K. Lieu, Chu-Pak Lau, Hung-Fat Tse and Ronald A. Li ...
http://circ.ahajournals.org/collection/ion-channelsmembrane-transport?page=6
*  Neuronal Ion Channels - QIAGEN
Neuronal Ion Channels RT2 Profiler PCR Array The Human Neuronal Ion Channels RT² Profiler PCR Array was developed to profile ... Neuronal Ion Channels RT2 Profiler PCR Array The Mouse Neuronal Ion Channels RT² Profiler PCR Array was developed to profile ... Neuronal Ion Channels RT2 Profiler PCR Array The Rat Neuronal Ion Channels RT² Profiler PCR Array was developed to profile ... Activated transmembrane ion channels allow ions into or out of cells. In neurons, these channels promote neurotransmission by ...
https://www.qiagen.com/nl/shop/genes-and-pathways/complete-biology-list/neuronal-ion-channels/
*  Light-gated ion channels | Feb 2007 | BioPhotonics
... artificially light-responsive ion channels can facilitate experimental manipulation, allowing neuro ... As ion channels influence many aspects of biology, ... Light-gated ion channels. BioPhotonics. Feb 2007 As ion ... Because neurons use ion channels to transmit sensory information, light-gated ion channels could restore the senses of those ... Light-gated ion channels could deliver drugs to target tissues, and light could trigger the channels to expand, allowing for ...
https://www.photonics.com/a39476/Light-gated_ion_channels
*  PhD Position: Experimental investigation of ligand-gated ion channels
Experimental investigation of ligand-gated ion channels, with Forschungszentrum Jülich - FZJ - Helmholtz Association. Apply ... PhD Position: Experimental investigation of ligand-gated ion channels. Forschungszentrum Jülich - FZJ - Helmholtz Association. ... The Department of Molecular Pharmacology offers state-of-the-art methods to study ligand-gated ion channels by ... we are looking for a PhD student to join our research group on ion channels and transporters. In the frame of a research ...
https://www.nature.com/naturecareers/job?id=676729&error=cookies_not_supported&code=042b6c1a-940f-43bf-aea0-b0eee6eb83be
*  Cyclic Nucleotide‐gated Ion Channels
... ion channels are activated by cAMP or cGMP, crucial intracellular messenger molecules that regulate a wide variety of ... Ion channels are membrane proteins that allow ions to diffuse across cellular membranes in a regulated manner. ... CNG channels are ion channels regulated by the direct binding of cyclic nucleotides. ... Gating is the process by which ion channels open and close to control the flow of ions. ...
http://www.els.net/WileyCDA/ElsArticle/refId-a0000091.html
*  Neuroscience] Re: Ion channel distributions
... are ion channel distributions constant? , , (2) Do particular cell types have well defined ion channel , distributions that are ... Neuroscience] Re: Ion channel distributions. Bill via neur-sci%40net.bio.net (by connelly.bill from gmail.com). Sun Nov 30 03: ... Classical examples of varying ion channel distribution included the high punctate density of voltage gated sodium channels at ... example does a Purkinje cell have a predictable ion channel , distribution?) , , (3) Are the answers to questions (1) and (2) ...
http://www.bio.net/bionet/mm/neur-sci/2008-November/062337.html
*  Voltage-dependent ion channels in T-lymphocytes. - PubMed - NCBI
... cataloguing the ion channels present in the cell membranes of T-lymphocytes and present new data on the types of ion channels ... The ion channels thus far described in these cells are strikingly similar to those found in nerve and muscle cells. Voltage- ... Voltage-dependent ion channels in T-lymphocytes.. DeCoursey TE, Chandy KG, Gupta S, Cahalan MD. ... gated potassium channels resembling delayed rectifier potassium channels in excitable cells are present in most T-lymphocytes, ...
https://www.ncbi.nlm.nih.gov/pubmed/2414315?dopt=Abstract
*  Voltage-Sensitive Ion Channels in Human B Lymphocytes | SpringerLink
Such channels control the transmembrane flow of ions by opening or closing in response to appropriate... ... Ion channels are protein pores that provide for the rapid movement of ions across cell membranes. ... Ion channels are protein pores that provide for the rapid movement of ions across cell membranes. Such channels control the ... and by allowing only specific types of ions to pass through (a property referred to as selectivity). Although ion channels have ...
https://link.springer.com/chapter/10.1007/978-1-4757-5803-0_14
*  Ion Channels in Hematopoietic and Mesenchymal Stem Cells
... Serena Pillozzi1 and Andrea Becchetti2 ... Serena Pillozzi and Andrea Becchetti, "Ion Channels in Hematopoietic and Mesenchymal Stem Cells," Stem Cells International, vol ...
https://www.hindawi.com/journals/sci/2012/217910/cta/
*  Ion channel modulators | Abcam
... standard ion channel modulators for popular targets including voltage & ligand gated sodium, potassium & calcium channels. ... Ion channel modulators Ion channels are essentially pore-forming membrane proteins where some drugs may directly or indirectly ... Join researchers worldwide and find ion channel modulators for your research. Browse all products related to Ion channel ... Ion channels may be a site of action for fast acting neurotransmitters such as GABA, with popular channels include sodium, ...
http://www.abcam.com/nav/agonists-activators-antagonists-and-inhibitors/ion-channel-modulators
*  Neurotransmitter-gated ion-channel (IPR006201) | InterPro | EMBL-EBI
Neurotransmitter ligand-gated ion channels are transmembrane receptor-ion channel complexes that open transiently upon binding ... Neurotransmitter-gated ion-channel transmembrane domain superfamily (IPR036719). *Neurotransmitter-gated ion-channel ligand- ... Neurotransmitter-gated ion-channel (IPR006201). Short name: Neur_channel Overlapping homologous superfamilies * ... GO:0034220 ion transmembrane transport Molecular Function. GO:0005216 ion channel activity GO:0004888 transmembrane signaling ...
http://www.ebi.ac.uk/interpro/entry/IPR006201
*  Ion Channels: A Laboratory Manual
CHAPTER 7 Single-Channel Recording of Ligand-Gated Ion Channels. INTRODUCTION. Single-Channel Recording of Ligand-Gated Ion ... CHAPTER 1 Ion Channels: History, Diversity, and Impact. INTRODUCTION. Ion Channels: History, Diversity, and Impact. Stephan ... Download a Free Excerpt from Ion Channels: A Laboratory Manual:. Index. Voltage-Gated Na+ Channels: Not Just for Conduction. ... The book...is an extremely useful guide for the study of ion channels. This volume is well written and describes in appropriate ...
https://cshlpress.com/default.tpl?action=full&cart=1552629822632323641&--eqskudatarq=1117
*  Postdoc position-Ion Channel Molecular Biology
... Dr. James S. Trimmer trimmer at life.bio.sunysb.edu Sat Aug 24 10:55:29 EST ... 15:5360; 16:4846; JBC 271:7084), and 2) interactions of K+ channel complexes with proteins important in determining subcellular ... Ongoing projects involve 1) characterization of subunit interactions within mammalian K+ channel complexes (Neuron 16:843; J. ...
http://www.bio.net/bionet/mm/cellbiol/1996-August/005130.html
*  Protein tags regulate key ion channel
"This adds a new chapter to the book of how cells control ion channel function: reversible peptide linkage." Ion channels are in ... target one or another ion channel." Goldstein's team discovered the type of ion channel known as background (or leak) potassium ... Ion channels allow ions such as potassium, sodium and calcium to flow in and out and so are key regulators of many fundamental ... The gradual doling out or sudden influx of ions through ion channels are the basis for those cellular activities that give us ...
http://www.innovations-report.com/html/reports/life-sciences/report-42756.html
*  Small Change Makes A Big Difference For Ion Channels - Redorbit
... the researchers could see the charge state of working ion channels in living cells. They saw that, in anion-selective channels ... One mediates inhibition by channeling anions, or negatively charged ions, while the other mediates excitation by channeling ... "These channels are the subject of a lot of computational studies. Before this paper, if researchers had to model these channels ... Small Change Makes A Big Difference For Ion Channels. by Sam Savage ...
http://www.redorbit.com/news/science/2058398/small_change_makes_a_big_difference_for_ion_channels/