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*  HCN4 - Wikipedia
Cyclic nucleotide-gated ion channel Funny current GRCh38: Ensembl release 89: ENSG00000138622 - Ensembl, May 2017 GRCm38: ... "Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and ... Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 is a protein that in humans is encoded by the ... "Entrez Gene: HCN4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4". Baruscotti M, Bucchi A, Viscomi C, ...
https://en.wikipedia.org/wiki/HCN4
*  Chloride channel - Wikipedia
For the channels, when the slow gate is closed, no ions permeate through the pore. When the slow gate is open, the fast gates ... Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many ... Thus, the protein could have both gates open, or both gates closed, or just one of the two gates open. Single-channel patch- ... Several families of voltage-gated channels and ligand-gated channels (e.g., the CaCC families) have been characterized in ...
https://en.wikipedia.org/wiki/Chloride_channel
*  Inward-rectifier potassium channel - Wikipedia
In this regard Kir channels are PIP2 ligand-gated ion channels. Kir channels are found in multiple cell types, including ... IRK channels possess a pore domain, homologous to that of voltage-gated ion channels, and flanking transmembrane segments (TMSs ... "Inwardly Recifying Potassium Channels". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and ... Bertil Hille (2001). Ion Channels of Excitable Membranes 3rd ed. (Sinauer: Sunderland, MA), p. 151. ISBN 0-87893-321-2. Hille, ...
https://en.wikipedia.org/wiki/Inward-rectifier_potassium_channel
*  Stochastic Ion Channel Gating and Probabilistic Computation in Dendritic Neurons | Springer for Research & Development
Although these ion channels are well known to operate stochastically, most computational models of... ... The electrical signals underlying neural computations are mediated by membrane ion channels. ... The electrical signals underlying neural computations are mediated by membrane ion channels. Although these ion channels are ... White JA, Klink R, Alonso A, Kay AR (1998) Noise from voltage-gated ion channels may influence neuronal dynamics in the ...
https://rd.springer.com/chapter/10.1007/978-1-4614-8094-5_24
*  PLOS Computational Biology: Stochastic Ion Channel Gating in Dendritic Neurons: Morphology Dependence and Probabilistic...
Using these tools we demonstrate that the impact of random ion channel opening depends on neuronal morphology and ion channel ... We show that in a realistic model of a neuron important for navigation and memory random gating of ion channels substantially ... However, the complexities of neuronal morphology, together with the large number of ion channels expressed by a single neuron, ... the brain is mediated through changes in the probability of random transitions between open and closed states of ion channels. ...
https://journals.plos.org/ploscompbiol/article/figure?id=10.1371/journal.pcbi.1000886.g008
*  Optimal-Sensitivity Analysis of Ion Channel Gating Kinetics, The Journal of Membrane Biology | 10.1007/s00232-004-0681-z |...
"Optimal-Sensitivity Analysis of Ion Channel Gating Kinetics, The Journal of Membrane Biology" on DeepDyve, the largest online ... Optimal-Sensitivity Analysis of Ion Channel Gating Kinetics. Optimal-Sensitivity Analysis of Ion Channel Gating Kinetics Kargol ... A sodium channel gating model based on single channel, macroscopic ionic and gating currents in the squid giant axon ... Gating of Shaker K+ channels II: the components of gating currents and a model of channel activation ...
https://www.deepdyve.com/lp/springer_journal/optimal-sensitivity-analysis-of-ion-channel-gating-kinetics-EEB0hJ2LPY
*  Ion channel gating and time interval omission: statistical inference for a two-state Markov model | Proceedings of the Royal...
Ion channel gating and time interval omission: statistical inference for a two-state Markov model. F. G. Ball, S. S. Davies, M ... Ion channel gating and time interval omission: statistical inference for a two-state Markov model ... Ion channel gating and time interval omission: statistical inference for a two-state Markov model. ... Ion channel gating and time interval omission: statistical inference for a two-state Markov model ...
http://rspb.royalsocietypublishing.org/content/255/1344/267
*  ligand-gated ion channels
... chrissy chrissy_4u2c at hotmail.com Thu Oct 30 07:30:23 EST 2003 *Previous message: UV laser for DNA ... And how does that relate to ligand-gated channels in general? *Previous message: UV laser for DNA-protein cross-linking ... With a multisubunit ion channel, where the subunits have multiple transmembrane helices, how do you tell which of a subunit's ...
http://www.bio.net/bionet/mm/proteins/2003-October/011318.html
*  Neurotransmitter-gated ion-channel (IPR006201) | InterPro | EMBL-EBI
Neurotransmitter-gated ion-channel transmembrane domain superfamily (IPR036719). *Neurotransmitter-gated ion-channel ligand- ... Neurotransmitter ligand-gated ion channels are transmembrane receptor-ion channel complexes that open transiently upon binding ... Neurotransmitter-gated ion-channel (IPR006201). Short name: Neur_channel Overlapping homologous superfamilies * ... Neurotransmitter-gated ion-channel (IPR006201) *5-hydroxytryptamine 3 receptor (IPR008132). *Gamma-aminobutyric acid A receptor ...
http://www.ebi.ac.uk/interpro/entry/IPR006201
*  Light-gated ion channels | Feb 2007 | BioPhotonics
... artificially light-responsive ion channels can facilitate experimental manipulation, allowing neuro ... As ion channels influence many aspects of biology, ... Light-gated ion channels. BioPhotonics. Feb 2007 As ion ... Because neurons use ion channels to transmit sensory information, light-gated ion channels could restore the senses of those ... Light-gated ion channels could deliver drugs to target tissues, and light could trigger the channels to expand, allowing for ...
https://www.photonics.com/a39476/Light-gated_ion_channels
*  PhD Position: Experimental investigation of ligand-gated ion channels
Experimental investigation of ligand-gated ion channels, with Forschungszentrum Jülich - FZJ - Helmholtz Association. Apply ... PhD Position: Experimental investigation of ligand-gated ion channels. Forschungszentrum Jülich - FZJ - Helmholtz Association. ... The Department of Molecular Pharmacology offers state-of-the-art methods to study ligand-gated ion channels by ... we are looking for a PhD student to join our research group on ion channels and transporters. In the frame of a research ...
https://www.nature.com/naturecareers/job?id=676729&error=cookies_not_supported&code=042b6c1a-940f-43bf-aea0-b0eee6eb83be
*  Cyclic Nucleotide‐gated Ion Channels
... ion channels are activated by cAMP or cGMP, crucial intracellular messenger molecules that regulate a wide variety of ... gated ion channels. Physiological Review 82(3): 769-824. Matulef K and Zagotta WN (2003) Cyclic nucleotide‐gated ion channels. ... Gating is the process by which ion channels open and close to control the flow of ions. ... Cyclic Nucleotide‐gated Ion Channels. Jie Zheng, University of California at Davis, Davis, California, USA Kimberly Matulef, ...
http://www.els.net/WileyCDA/ElsArticle/refId-a0000091.html
*  Structures: Neurotransmitter-gated ion-channel transmembrane domain (IPR006029) | InterPro | EMBL-EBI
Structures: Neurotransmitter-gated ion-channel transmembrane domain (IPR006029). PDBe. The Protein Data Bank (PDB) is a ...
http://www.ebi.ac.uk/interpro/entry/IPR006029/structures
*  Light-gated ion channel - Wikipedia
... ligand-gated ion channels, mechanosensitive ion channels, and temperature-gated ion channels. Most light-gated ion channels ... Light-gated ion channels are a family of ion channels regulated by electromagnetic radiation. Other gating mechanisms for ion ... Other types of gated ion channels, ligand-gated and voltage-gated, have been synthesized with a light-gated component in an ... Light-gated ion channels function in a similar manner to other gated ion channels. Such transmembrane proteins form pores ...
https://en.wikipedia.org/wiki/Light-gated_ion_channel
*  Voltage-gated ion channel - Wikipedia
... voltage-gated ion channels directionally propagate electrical signals. Voltage-gated ion-channels are usually ion-specific, and ... DB Voltage-gated ion channel subunits The IUPHAR Compendium of Voltage-gated Ion Channels 2005 Voltage-Dependent Anion Channels ... Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the ... polycystin cation channels, glutamate-gated ion channels, calcium-dependent chloride channels, monovalent cation:proton ...
https://en.wikipedia.org/wiki/Voltage-gated_ion_channel
*  Ligand-gated ion channel - Wikipedia
... calcium channel Calcium-activated potassium channel Cyclic nucleotide-gated ion channel Acid-sensing ion channel Ryanodine ... and its role in gating ion channels represents a novel role for the molecule. In contrast to ligand-gated ion channels, there ... If these receptors are ligand-gated ion channels, a resulting conformational change opens the ion channels, which leads to a ... "Revised Recommendations for Nomenclature of Ligand-Gated Ion Channels". IUPHAR Database of Receptors and Ion Channels. ...
https://en.wikipedia.org/wiki/Ligand-gated_ion_channel
*  Neurotransmitter-gated ion-channel ligand-binding domain superfamily (IPR036734) | InterPro | EMBL-EBI
Neurotransmitter ligand-gated ion channels are transmembrane receptor-ion channel complexes that open transiently upon binding ... Neurotransmitter-gated ion-channel ligand-binding domain superfamily (IPR036734). Short name: Neur_chan_lig-bd_sf ... Structure and gating of the glutamate receptor ion channel.. Trends Neurosci. 27 321-8 2004 ... All known sequences of subunits from neurotransmitter-gated ion-channels are structurally related. They are composed of a large ...
http://www.ebi.ac.uk/interpro/entry/IPR036734
*  G protein-gated ion channel - Wikipedia
G protein-gated ion channels are a family of transmembrane ion channels in neurons and atrial myocytes that are directly gated ... Generally, G protein-gated ion channels are specific ion channels located in the plasma membrane of cells that are directly ... G protein-gated ion channels are associated with a specific type of G protein-coupled receptor. These ion channels are ... G proteins can also directly gate certain calcium ion channels in neuronal cell membranes. Although membrane ion channels and ...
https://en.wikipedia.org/wiki/G_protein-gated_ion_channel
*  Cyclic nucleotide-gated ion channel - Wikipedia
Cyclic nucleotide-gated ion channels or CNG channels are ion channels that function in response to the binding of cyclic ... Cyclic nucleotide gated channel alpha-subunits include Cyclic nucleotide-gated channel alpha 1 Cyclic nucleotide-gated channel ... Cyclic nucleotide-gated channel beta 1 Cyclic nucleotide-gated channel beta 3 The structure of the pore is similar to other ion ... alpha 2 Cyclic nucleotide-gated channel alpha 3 Cyclic nucleotide-gated channel alpha 4 Cyclic nucleotide gated channel beta- ...
https://en.wikipedia.org/wiki/Cyclic_nucleotide%E2%80%93gated_ion_channel
*  Cell Signaling & Neuroscience:Voltage-Gated Ion Channels | Sigma-Aldrich
The majority of ion channels fall into two broad categories: voltage-gated ion channels (VGIC) and ligand-gated ion channels ( ... The majority of ion channels fall into two broad categories: voltage-gated ion channels (VGIC) and ligand-gated ion channels ( ... Other Ion Channels. Antibodies to Other Ion Channels. Ion Exchangers and Co-Transporters. Ion Probes. Ionophores. Antibodies to ... the ATP-gated channels, the cyclic nucleotide-gated channels (CNG) and aquaporins (water channels). ...
https://www.sigmaaldrich.com/life-science/cell-biology/ion-channels/voltage-gated.html
*  'ligand gated ion channels' Protocols and Video...
Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue', 'In Vivo ... GABA-activated Single-channel and Tonic Currents in Rat Brain Slices'. ... Video articles in JoVE about ligand gated ion channels include 'Isolation of Human Atrial Myocytes for Simultaneous ... Ligand-Gated Ion Channels: A subclass of ion channels that open or close in response to the binding of specific Ligands. ...
https://www.jove.com/keyword/ligand+gated+ion+channels?page=3
*  Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel
General anaesthetic actions on ligand-gated ion channels. Cell Mol Life Sci. 1999;55:1278-303. [PMC free article] [PubMed] ... 3. Hilf RJ, Dutzler R. X-ray structure of a prokaryotic pentameric ligand-gated ion channel. nature. 2007;452:375-9. [PubMed] ... Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel. Yun Weng, PhD,1 Liya Yang, PhD,1 Pierre-Jean ... Pentameric ligand-gated ion channels from the superfamily containing gamma aminobutyric acid type A (GABAA), glycine, 5HT3, and ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2897236/?lang=en-ca
*  Dysfunctional Hyperpolarization-Activated Cyclic Nucleotide-gated Ion Channels in Cardiac Diseases
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels comprise a family of cation channels activated by ... Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor alpha or beta. ... Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation. Physiol Rev ... HCN CHANNEL BLOCKERS. It is well known that slow heart beat is good for the heart. Therefore, HCN channels become the main ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382016000200203&lng=en&tlng=en
*  Antibodies to Glutamate Receptors - Antibodies to Ligand-Gated Ion Channels | Sigma-Aldrich
Ionotropic glutamate receptors form the ion channel pore that activates when glutamate binds to the receptor. There are also ... Antibodies to Ion Channels > Antibodies to Ligand-Gated Ion Channels > Antibodies to Glutamate Receptors ... Ionotropic glutamate receptors form the ion channel pore that activates when glutamate binds to the receptor. There are also ...
https://www.sigmaaldrich.com/life-science/cell-biology/antibodies/antibody-products.html?TablePage=18437389
*  Toxins | Free Full-Text | From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules
This key function has two consequences: (i) these receptor channels are major targets for drug discovery because of their ... Ligand-gated ion channels (LGIC) play a central role in inter-cellular communication. ... Ligand-gated ion channels (LGIC) play a central role in inter-cellular communication. This key function has two consequences: ( ... Nasiripourdori A, Taly V, Grutter T, Taly A. From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules. Toxins. ...
http://www.mdpi.com/2072-6651/3/3/260/xml