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*  Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes | Diabetes Care
Interleukin-1 system gene polymorphisms are associated with fat mass in young men. J Clin Endocrinol Metab 2006; 91: 2749- 2754 ... Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 2007; 356: 1517- 1526. ... M.Y.D. is listed as the inventor of a patent filed in 2003 for the use of an interleukin-1 receptor antagonist for the ... OBJECTIVE Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is ...
http://care.diabetesjournals.org/content/32/9/1663
*  Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer
... Viet, Hung Trinh Vietnam National University, ... interleukin-1 receptor antagonist; polymorphism; VNTR; colorectal cancer National Category Medical and Health Sciences ... There is evidence that pro-inflammatory cytokines such as interleukin-1 (IL-1) are critically involved with tumour progression ... IL-1 receptor antagonist (IL-1Ra) is known to down regulate and limit the inflammatory response. Therefore we attempted to ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:661605
*  Interleukin-1 Receptor Antagonist Expression in Human Endothelial Cells and Atherosclerosis | Arteriosclerosis, Thrombosis, and...
Interleukin-1β in coronary arteries of patients with ischemic heart disease. Arterioscler Thromb Vasc Biol.. 1996;16:1000-1006. ... Interleukin-1 in myocardium and coronary arteries of patients with dilated cardiomyopathy. J Mol Cell Cardiol.. 1998;30:215-223 ... Interleukin-1 Receptor Antagonist Expression in Human Endothelial Cells and Atherosclerosis. Rachael Dewberry, Hazel Holden, ... Detection of an interleukin-1 intracellular receptor antagonist mRNA variant. Biochem Biophys Res Commun.. 1998;244:91-95. ...
http://atvb.ahajournals.org/content/20/11/2394
*  Background and purpose: The inflammatory cytokine interleukin-1 (IL-1) has profound actions - Polo-Like Kinases and Aurora...
Background and purpose: The inflammatory cytokine interleukin-1 (IL-1) has profound actions. Background and purpose: The ... blood-brain barrier model transcytosis microtubule Intro Interleukin-1 (IL-1) is definitely a pro-inflammatory cytokine that ... Author technumberCategories Cellular ProcessesTags DMH-1, Mouse monoclonal to BMPR2 Post navigation. Previous Previous post: ... inflammatory cytokine interleukin-1 (IL-1) has profound actions in the brain causing neuronal cell death and exacerbating mind ...
http://technumber.com/2016/03/29/background-and-purpose-the-inflammatory-cytokine-interleukin-1-il-1-has-profound-actions/
*  Transcriptional activity of tumor necrosis factor-alpha gene in peripheral blood mononuclear cells in patients with coronary...
Enayati S, Seifirad S, Amiri P, Abolhalaj M, Mohammad-Amoli M. Interleukin-1 beta, interferon-gamma, and tumor necrosis factor- ... Increased plasma C-reactive protein and interleukin-6 concentrations in patients with slow coronary flow. Clin Chim Acta 2007; ... Atherosclerosis 2008; 197(1): 257-63.. Cin VG, Pekdemir H, Camsar A, Cicek D, Akkus MN, Parmaksyz T, et al. Diffuse intimal ... Atherosclerosis 2007; 193(1): 20-7.. De Palma C, Meacci E, Perrotta C, Bruni P, Clementi E. Endothelial nitric oxide synthase ...
http://www.arya.mui.ac.ir/index.php/arya/article/view/1491
*  Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10...
Interleukin 10 (IL-10) is an important contra-inflammatory cytokine which induces downregulation of pro-inflammatory cytokines. ... Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 ... Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 ... IL-1 beta, TNF-alpha) and of IL-1 receptor antagonist were assessed in peripheral PMN.To investigate whether PMN from patients ...
http://www.ikmb.uni-kiel.de/publications/increased-secretion-pro-inflammatory-cytokines-circulating-polymorphonuclear
*  interleukin 7 recombinant human interleukin 7 Gentaur Molecular Products
... order interleukin 7 recombinant human interleukin 7 , How to use: interleukin 7 recombinant human interleukin 7 , suppo ... Kuiper 1 5521 DG Eersel Nederland. Tel 0208-080893 Fax 0497-517897. nl@gentaur.com ...
http://www.clonagen.com/product_description.php?id=8075&product_name=recombinant%20human%20interleukin%207
*  Interleukin 1 Beta by Chemiluminescence
... ,ARUP Laboratories is a national reference laboratory and a worldwide leader in ... Interleukin 2by ELISA. 2. Interleukin 6 by Chemiluminescence. 3. Interleukin 2 Receptorby Chemiluminescence. 4. Interleukin 8by ...
http://www.bio-medicine.org/medicine-products/Interleukin-1-Beta-by-Chemiluminescence-23402-1/
*  Interleukin-1 conserved site (IPR020877) | InterPro | EMBL-EBI
Interleukin-1 conserved site (IPR020877). Short name: IL-1_CS Description. Interleukin-1 alpha and interleukin-1 beta (IL-1 ... Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.. Proc. Natl. Acad. Sci. U.S.A. 86 9667-71 1989 ... Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors.. J. ... The highest degree of similarity is to the human and murine interleukin-1 receptors, although both proteins are related to a ...
http://www.ebi.ac.uk/interpro/entry/IPR020877
*  Interleukin-1 Family Cytokines in Liver Diseases
H. England, H. R. Summersgill, M. E. Edye, N. J. Rothwell, and D. Brough, "Release of interleukin-1α or interleukin-1β depends ... B. Kim, Y. Lee, E. Kim et al., "The interleukin-1α precursor is biologically active and is likely a key alarmin in the IL-1 ... S. Shrivastava, A. Mukherjee, R. Ray, and R. B. Raya, "Hepatitis C virus induces interleukin-1β (IL-1β)/IL-18 in circulatory ... Y. Gu, K. Kuida, H. Tsutsui et al., "Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme," ...
https://www.hindawi.com/journals/mi/2015/630265/ref/
*  Interleukin-1 receptor type 1 (IPR004076) | InterPro | EMBL-EBI
Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.. Proc. Natl. Acad. Sci. U.S.A. 86 9667-71 1989 ... Interleukin-1 alpha and interleukin-1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of ... Interleukin-1 receptor family (IPR015621) *Interleukin-1 receptor type I/II (IPR004074) *Interleukin-1 receptor type 1 ( ... This entry represents Interleukin-1 receptor type 1 (IL1R1), the crystal structure of the soluble extracellular part of type-I ...
http://www.ebi.ac.uk/interpro/entry/IPR004076
*  Interleukin-1 Modulation of Human Placental Trophoblast Proliferation
C A Dinarello, "Interleukin-1 and its biologically related cytokines," Advances in Immunology, vol. 44, pp. 153-205, 1989. View ... interleukin-1. β. , and interleukin-1 receptor type I mRNA during preimplantation mouse development," Journal of Reproductive ... S W Kauma, "Interleukin-1 beta stimulates colony-stimulating factor-1 production in human term placenta," The Journal of ... R Romero, Y K Wu, D T Brody, E Oyarzun, G W Duff, and S K Durum, "Human decidua: a source of interleukin-1," Obstetrics & ...
https://www.hindawi.com/journals/mi/2006/079359/ref/
*  'interleukin 1' Protocols and Video...
... interleukin 1' include 'Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene ... Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay', 'Screening Assay ... Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells', 'Systematic ... Interleukin-1alpha and Interleukin-1beta. The biological effects of Il-1 include the ability to replace macrophage requirements ...
https://www.jove.com/keyword/interleukin+1
*  Interleukin-1 receptor - Wikipedia
Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I ... Arend WP (1991). "Interleukin 1 receptor antagonist. A new member of the interleukin 1 family". J. Clin. Invest. 88 (5): 1445- ... Wesche H, Korherr C, Kracht M, Falk W, Resch K, Martin MU (March 1997). "The interleukin-1 receptor accessory protein (IL-1RAcP ... Receptors, Interleukin-1 at the US National Library of Medicine Medical Subject Headings (MeSH). ...
https://en.wikipedia.org/wiki/Interleukin-1_receptor
*  Interleukin-1 family - Wikipedia
Liu N, Li X, Liu C, Zhao Y, Cui B, Ning G (2010). "The association of interleukin-1alpha and interleukin-1beta polymorphisms ... The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and ... The interleukin-1 superfamily has 11 members, which have similar gene structure, although originally it contained only four ... Dinarello CA (2011). "Interleukin-1 in the pathogenesis and treatment of inflammatory diseases". Blood. 117 (14): 3720-32. doi: ...
https://en.wikipedia.org/wiki/Interleukin-1_family
*  Human interleukin 1. Purification to homogeneity. | JEM
Human interleukin 1. Purification to homogeneity.. S R Kronheim, C J March, S K Erb, P J Conlon, D Y Mochizuki, T P Hopp ... We have purified human interleukin 1 (IL-1) to homogeneity by a simplified procedure that results in excellent yields of pure ... IL-1, secreted by human peripheral blood macrophages that have been stimulated with Staphylococcus aureus, was purified by ion ... No molecular weight heterogeneity was observed, in contrast to findings for mouse IL-1 and earlier reports of human IL-1. ...
http://jem.rupress.org/content/161/3/490
*  WikiGenes - IL1A - interleukin 1, alpha
Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 ... Heterogeneity in interleukin (IL)-1 receptors expressed on human B cell lines. Differences in the molecular properties of IL-1 ... Interleukin 1 alpha gene polymorphism as a susceptibility factor in Alzheimer's disease and its influence on the extent of ... The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor. Mosley, B., ...
https://www.wikigenes.org/e/gene/e/3552.html
*  interleukin-1 (IL-1)
... By Ivan Suarez Robles 08 Feb, 2011 A cytokine that is involved with various inflammatory activities. ...
https://web.stanford.edu/group/hopes/cgi-bin/hopes_test/glossary/interleukin-1-il-1/
*  Interleukin-1 beta - Proteopedia, life in 3D
3] Mizutani H, Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human ... Human Interleukin-1 Beta THREE-DIMENSIONAL STRUCTURE OF IL-1β The molecule contains 12 antiparallel β-strands. The molecule has ... 5] Guy P. A. Vigers, Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β, Nature 1997,386,190- ... 4] B Veerapandian, Structure and function of interleukin-1, based on crystallographic and modeling studies,Biophys J.1992, ...
http://proteopedia.org/wiki/index.php/Interleukin-1_beta
*  Topological frustration and the folding of interleukin-1 beta. - PubMed - NCBI
The cytokine, interleukin-1beta (IL-1beta), adopts a beta-trefoil fold. It is known to be much slower folding than similarly ... Topological frustration and the folding of interleukin-1 beta.. Gosavi S1, Chavez LL, Jennings PA, Onuchic JN. ... 1. Center for Theoretical Biological Physics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA.. ...
https://www.ncbi.nlm.nih.gov/pubmed/16469330
*  INTERLEUKIN 1 | The Journal of Rheumatology
The Journal of Rheumatology January 1 2017, 44 (1) 102-109; DOI: https://doi.org/10.3899/jrheum.160518 ...
http://www.jrheum.org/keyword/interleukin-1
*  Receptors interleukin-1 - Biology-Online Dictionary
receptors, interleukin-1 specific molecular sites or structures on cells with which interleukin-1 reacts or to which it binds ... The il-1 receptor on t-lymphocytes and fibroblasts is composed of a single polypeptide chain that binds both il-1 alpha and il- ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Receptors_interleukin-1&oldid=65867" ... 1 beta. The molecular weight of this high-affinity receptor is believed to be 80 kD. ...
https://www.biology-online.org/dictionary/Receptors_interleukin-1
*  Downregulation of Renin Gene Expression by Interleukin-1 | Hypertension
Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis. 1990;161:79 ... Downregulation of Renin Gene Expression by Interleukin-1. Nenad Petrovic, Colleen M. Kane, Curt D. Sigmund, Kenneth W. Gross ... Interleukin-1 and interleukin-1 antagonism in sepsis, systemic inflamatory response syndrome, and septic shock. Shock. 1995;3: ... Downregulation of Renin Gene Expression by Interleukin-1. Nenad Petrovic, Colleen M. Kane, Curt D. Sigmund and Kenneth W. Gross ...
http://hyper.ahajournals.org/content/30/2/230
*  RCSB PDB - Protein Feature View - Interleukin-1 beta - P01584 (IL1B HUMAN)
Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). UniProt ...
https://www.rcsb.org/pdb/protein/P01584
*  Anti-Interleukin-1 in Diabetes Action - Full Text View - ClinicalTrials.gov
Anti-Interleukin-1 in Diabetes Action (AIDA). The safety and scientific validity of this study is the responsibility of the ... The anti-interleukin-1 in type 1 diabetes action trial--background and rationale. Diabetes Metab Res Rev. 2009 May;25(4):321-4 ... Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled ... The aim of the Anti-Interleukin-1 in Diabetes Action trial (AIDA) study is to test the feasibility, safety/tolerability and ...
https://clinicaltrials.gov/show/NCT00711503