Annotations: 7NYG
cellular response to interleukin-1. *response to interleukin-1. *positive regulation of canonical NF-kappaB signal transduction ...
data 1IAN
Sb 203580 is a Specific Inhibitor of a Map Kinase Homologue which is Stimulated by Cellular Stresses and Interleukin-1 FEBS ... 6 1 Y 1 A HIS 0 ? A HIS 6 7 1 Y 1 A HIS 1 ? A HIS 7 8 1 Y 1 A SER 2 ? A SER 8 9 1 Y 1 A GLN 3 ? A GLN 9 10 1 Y 1 A GLU 4 ? A ... HIS n 1 6 HIS n 1 7 HIS n 1 8 SER n 1 9 GLN n 1 10 GLU n 1 11 ARG n 1 12 PRO n 1 13 THR n 1 14 PHE n 1 15 TYR n 1 16 ARG n 1 17 ... 6 PRO PRO A . n A 1 13 THR 13 7 7 THR THR A . n A 1 14 PHE 14 8 8 PHE PHE A . n A 1 15 TYR 15 9 9 TYR TYR A . n A 1 16 ARG 16 ...
RCSB PDB - 6LFO: Cryo-EM structure of a class A GPCR monomer
Here we present the cryo-electron microscopy structures of interleukin-8 (IL-8, also known as CXCL8)-activated human CXC ...
RCSB PDB - 6BFN: Crystal structure of human IRAK1
Interleukin 1 (IL-1) receptor-associated kinases (IRAKs) are serine/threonine kinases that play critical roles in initiating ... and interleukin 1 receptor (IL-1R) mediated signaling pathways. Upon ligand binding, TLRs and IL-1Rs recruit adaptor proteins, ... N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide. C20 H21 N5 O3. RAFFLDOJXQAJPF-UHFFFAOYSA-N. ...