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*  Plus it
2001) Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1. Mol Biol Cell 12:2975 ... 9E,F). In contrast, CHL1-Fc did not colocalize with α6 integrin and showed only a weak colocalization with α7 integrin (Fig. 9G ... Colocalization of CHL1; vitronectin; and αv or α3 integrin subunit (V/α/C), β1 or β3 (V/β/C) integrin subunit, or PAI-2 (V/P/C ... Colocalization of vitronectin and αv or α3 integrin subunit (V/α) and β1 or β3 (V/β) integrin subunit is shown in turquoise. ...
http://www.jneurosci.org/content/34/44/14606
*  JCI - Induction of B7-1 in podocytes is associated with nephrotic syndrome
Functions of alpha3beta1 integrin. Curr. Opin. Cell Biol. 2000. 12:548-553. View this article via: PubMed CrossRef Google ... via α3β1 integrin (8) and α-/β-dystroglycans (9, 10). α3β1 integrin represents a receptor for certain isoforms of laminin, ... α3β1 integrin regulates epithelial cytoskeletal organization. J. Cell Sci. 1999. 112:2925-2935. View this article via: PubMed ... As early as 6 and 24 hours, B7-1 is induced by PAN, whereas α3 integrin levels remain unchanged. (F) B7-1 is not expressed in ...
https://www.jci.org/articles/view/20402
*  Ying Wei, MD | UCSF Helen Diller Family Comprehensive Cancer Center
Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1. Mol Biol Cell. 2001 Oct; 12 ... Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. J Cell Biol. 2009 ... Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary ... Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. J Cell Biol. 2003 Oct 13 ...
http://cancer.ucsf.edu/people/profiles/wei_ying.3742
*  Model of TGF-β1 signaling. The schematic illustration | Open-i
Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. ... Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. ... suggesting a role for integrin signaling. Primary epithelial cells deficient in their prominent laminin receptor, alpha3beta1, ... suggesting a role for integrin signaling. Primary epithelial cells deficient in their prominent laminin receptor, alpha3beta1, ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2654298_JCB_200806067_RGB_Fig8&req=4
*  The Role of Wnt Signaling in Physiological and Pathological Angiogenesis | Circulation Research
Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. J Cell Biol. 2009 ... TGFβ receptors can associate with α3β1 integrin and cadherins (VE-cadherin in endothelial cells79,80 and E-cadherin in the ...
http://circres.ahajournals.org/content/107/8/943
*  Reactome | Laminin-211 [extracellular region]
Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Homo sapiens) * Integrin alpha3beta1, alpha6beta4: ... Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ... Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Homo sapiens) * Integrin alpha6beta1:Laminin-211, 221, 332, ... Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Homo sapiens) * Integrin alpha7beta1:Laminin-211, 221, 411, 512, ...
https://reactome.org/content/detail/R-HSA-216003
*  Cell Adhesion Molecules in Carcinoma Invasion and Metastasis | SpringerLink
Shang M, Koshikawa N, Schenk S, Quaranta V (2001) The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 ... Kim Y, Kugler MC, Wei Y, Kim KK, Li X, Brumwell AN, Chapman HA (2009) Integrin alpha3beta1-dependent beta-catenin ... DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO (1997) alpha3beta1 Integrin is required for normal ... Margadant C, Raymond K, Kreft M, Sachs N, Janssen H, Sonnenberg A (2009) Integrin alpha3beta1 inhibits directional migration ...
https://link.springer.com/chapter/10.1007/978-1-4419-7203-3_1
*  The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons | PNAS
2000) Reelin binds alpha3beta1 integrin and inhibits neuronal migration. Neuron 27:33-44. ... Given that the N-terminal fragment is able to bind α3β1 integrin receptors (11) and that blocking β1/β3-containing integrin ... 2000) Sodium dodecyl sulfate-stable complexes of echistatin and RGD-dependent integrins: A novel approach to study integrins. ... 4B and 4D), we propose that the signaling pathway requires binding of the N-R2 fragment to integrin receptors. It is yet ...
https://www.pnas.org/content/106/17/7227?ijkey=6bb2d59318ec77c9d5e2ceade125e61af360d772&keytype2=tf_ipsecsha
*  β1 Integrins in Radial Glia But Not in Migrating Neurons Are Essential for the Formation of Cell Layers in the Cerebral Cortex ...
2000) Reelin binds alpha3beta1 integrin and inhibits neuronal migration. Neuron 27:33-44. ... Integrins and reelin signaling. The integrin α3β1 has also been reported to bind to reelin and to transmit a reelin detachment/ ... Integrins and the development of the cerebral cortex. Although our findings show that β1 integrins in cortical neurons are not ... Integrins and glial-guided migration. The function of β1 integrins in cell migration during cortical development has been ...
http://www.jneurosci.org/content/27/50/13854.long
*  Recombinant Human TINAG protein (ab162129) | Abcam
Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic ...
https://www.abcam.com/recombinant-human-tinag-protein-ab162129.html
*  Spontaneous Bacterial Keratitis in CD36 Knockout Mice | IOVS | ARVO Journals
Thorne RF Marshall JF Shafren DR Gibson PG Hart IR Burns GF . The integrins alpha3beta1 and alpha6beta1 physically and ... Stepp MA . Corneal integrins and their functions. Exp Eye Res. 2006;83:3-15. [CrossRef] [PubMed] ... and α3β1 and α6β1 integrins. 34 -38 Interestingly, collagen and thrombospondin are major components of the corneal epithelial ... that digest extracellular matrix and integrins. In particular MMP2 and MMP9 are known to cleave specifically type 4 collagen, ...
https://iovs.arvojournals.org/article.aspx?articleid=2126531
*  In silico docking of urokinase plasminogen activator and integrins | BMC Bioinformatics | Full Text
Importantly we found that the binding mode was the same on different integrins and in both configurations. To get a molecular ... We have modeled the interaction of urokinase on two integrins, αIIbβ3 in the open configuration and αvβ3 in the closed ... However, the tri-dimensional structure of urokinase, urokinase receptor and integrins is known. ... point to an interaction of the kringle domain of uPA at the boundary between α and β chains on the surface of the integrins. ...
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-S2-S8
*  Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous cell carcinoma cells
Kawano K, Kantak SS, Murai M, Yao CC and Kramer RH: Integrin alpha3beta1 engagement disrupts intercellular adhesion. Exp Cell ... Moro L, Dolce L, Cabodi S, Bergatto E, Erba E Boeri, Smeriglio M, Turco E, Retta SF, Giuffrida MG, Venturino M, et al: Integrin ... For instance, in the process of cell adhesion, integrins bind to extracellular matrix proteins, which in turn may stimulate ... a complex involving integrins and EGFR is formed, and EGFR is subsequently phosphorylated on tyrosines 845, 1068, 1086 and 1173 ...
https://spandidos-publications.com/etm/14/2/953
*  Plus it
Functions of alpha3beta1 integrin. Curr Opin Cell Biol 2000;12:548-53. ... The α-3 integrin expression in the tumor section was stained by Alex Fluor 488-conjugated α-3 integrin antibody (1:500) for 1 ... To show the α-3 integrin-dependent uptake, excess amount of α-3 integrin antibody, or free OA02 peptide was added before the ... To show the overexpression of α-3 integrin, SKOV-3 and ES-2 cells were incubated with Alex Fluor 488-conjugated α-3 integrin ...
http://cancerres.aacrjournals.org/content/72/8/2100
*  Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization
The integrins alpha3beta1 and alpha6beta1 physically and functionally associate with CD36 in human melanoma cells. Requirement ... Integrins and tetraspanins are required for CD36 internalization. The physical association of CD36 with integrins and ... Human CD9, CD81 and β2 integrin plasmids were obtained from Addgene. Human β1 integrin cDNA was from the Hospital for Sick ... Tetraspanins scaffold CD36-integrin complexes. The preceding experiments suggest the existence of tripartite CD36/integrin/ ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3586299/?lang=en-ca
*  Christopher Walsh | Harvard Catalyst Profiles | Harvard Catalyst
Reelin binds alpha3beta1 integrin and inhibits neuronal migration. Neuron. 2000 Jul; 27(1):33-44. PMID: 10939329. ...
https://connects.catalyst.harvard.edu/Profiles/display/Person/9592
*  Cyclosporin safety in a simplified rat brain tumor implantation model
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. Am J Pathol 2010;177:1534- ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000100011&lng=en&nrm=iso&tlng=en
*  The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis | Journal of Biomedical Science | Full Text
Laminin-10/11 mediates cell adhesion through integrin alpha3 beta1. J Biol Chem. 1998;273(25):15854-9.View ArticlePubMedGoogle ... CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions. Mol Biol Cell. ... integrin-beta1, CA199, and CEA. Mol Biotechnol. 2012;52(1):59-67.View ArticlePubMedGoogle Scholar. ... co-expression of Lu/BCAM and integrin on the cell surface is responsible for adhesion of hepatocellular carcinoma cells [9]. ...
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-017-0360-x
*  Frontiers | Professional antigen presenting cells in human herpesvirus 8 infection | Immunology
Akula, S. M., Pramod, N. P., Wang, F. Z., and Chandran, B. (2002). Integrin alpha3beta1 (CD 49c/29) is a cellular receptor for ... Utilizing heparan sulfate, cell surface integrins, and DC-SIGN for binding and entry, HHV-8 establishes infection in ... 2008). Kaposi's sarcoma-associated herpesvirus forms a multimolecular complex of integrins (alphaVbeta5, alphaVbeta3, and ... as well as integrins including α3β1 (Ammon et al., 2000), which presumably renders them susceptible to HHV-8 infection. An ...
https://www.frontiersin.org/articles/10.3389/fimmu.2012.00427/full
*  Frontiers | Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes | Pharmacology
2009). Mechanical forces and TGFbeta1 reduce podocyte adhesion through alpha3beta1 integrin downregulation. Nephrol. Dial. ...
https://www.frontiersin.org/articles/10.3389/fphar.2014.00071/full
*  Polleux F[au] - PubMed - NCBI
Netrin-1-alpha3beta1 integrin interactions regulate the migration of interneurons through the cortical marginal zone. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Polleux+F%5Bau%5D&dispmax=50
*  CSIRO PUBLISHING | Reproduction, Fertility and Development
Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses tothrombospondin-1.CrossRef , 1: ... Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses tothrombospondin-1. Mol. Biol. ... Burghardt, R. C., Johnson, G. A., Jaeger, L. A., Ka, H., Garlow, J. E., Spencer, T. E., and Bazer, F. W. (2002). Integrins and ... Integrins and extracellular matrix proteins at the maternal-fetal interface in domestic animals.CrossRef , 1:CAS:528:DC% ...
http://www.publish.csiro.au/rd/RD16435
*  Tissue Factor and PAR2 Signaling in the Tumor Microenvironment | Arteriosclerosis, Thrombosis, and Vascular Biology
Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. J Cell Biol. 2004; 164: 935-941 ... 39 and binding of VIIa promotes the association of TF with integrins α3β1 and α6β1. The association of TF with these integrins ... Dorfleutner A, Hintermann E, Tarui T, Takada Y, Ruf W. Crosstalk of integrin α3β1 and tissue factor in cell migration. Mol Biol ... TF is constitutively associated with β1 integrins that regulate TF-VIIa-PAR2 signaling. PAR2 signaling through canonical G- ...
http://atvb.ahajournals.org/content/29/12/1999
*  Integrin α3β1-dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts | JCB
alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice. J. Clin. Invest. 118: 965-974 ... For co-IP of myc-TGF-βR1 and α3 integrin or E-cadherin, 1% NP-40 lysates were immunoprecipitated with myc mAb for α3 integrin ... integrin-linked kinase in EMT, also implying an important role for β1 integrins in the process (Lee et al., 2004; Oloumi et al ... B) α3 integrin only immunoprecipitates with myc-TGF-βR1 in α3 wt cells but not in H249A mutant cells. (C) Confocal microscopy ...
http://jcb.rupress.org/content/184/2/309