Very Late Antigen-1 Mediates Corneal Lymphangiogenesis | IOVS | ARVO Journals
Pozzi A Wary KK Giancotti FG Gardner HA . Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in ... 18 The specific roles of integrins in LG are still largely unknown. VLA-1 (very late antigen-1), also known as integrin α1β1, ... Stepp MA . Corneal integrins and their functions. Exp Eye Res. 2006;83:3-15. [CrossRef] [PubMed] ... Integrins are known to have an essential role in the LG process by mediating cell interactions with the extracellular matrix. ...https://iovs.arvojournals.org/article.aspx?articleid=2188573
CD11b+GR1+ Myeloid Cells Secrete NGF and Promote Trigeminal Ganglion Neurite Growth: Implications for Corneal Nerve...
Suzuki K Okuno T Yamamoto M Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature ... Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature . 2003; 424: 398-405. [CrossRef] [PubMed] ...http://iovs.arvojournals.org/article.aspx?articleid=2127625
Bevacizumab as a Potent Inhibitor of Inflammatory Corneal Angiogenesis and Lymphangiogenesis | IOVS | ARVO Journals
VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins. ...https://iovs.arvojournals.org/article.aspx?articleid=2164140
The Antiangiogenic Effects of Integrin α5β1 Inhibitor (ATN-161) In Vitro and In Vivo | IOVS | ARVO Journals
... regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci U S A. 1997;94:13612-13617. [CrossRef] [PubMed] ... The angiogenic effects of integrin α5β1 have been well documented. 26,36,37 However, the effects of the integrin α5β1 inhibitor ... Purpose.: Integrin α5β1 is involved in the development of choroidal neovascularization (CNV). Thus, the inhibition of integrin ... The expression of α5β1 integrin is upregulated in response to angiogenic factors, 38 and the interaction between α5β1 integrin ...https://iovs.arvojournals.org/article.aspx?articleid=2165433
Functional Impact of Collagens on the Activity Directed by the Promoter of the α5 Integrin Subunit Gene in Corneal Epithelial...
Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin. J Clin ... which have been reported to normally express the integrin subunits α2, α3, α4, α5, α6, αv, α9, β1, β4, and β5.21,22 Integrins, ... α5 integrin subunit gene despite that the α5β1 integrin is not a collagen-binding receptor. ... α5 integrin subunit gene in CECs despite that α5β1 is an FN but not a collagen-binding integrin. ...https://iovs.arvojournals.org/article.aspx?articleid=2451413