... antibodies to three distinct epitopes on the RBD neutralized the virus with half-maximal inhibitory concentrations (IC50 values ... Delta and Omicron variants at concentrations of ~7-100 ng ml-1. These antibodies target an hACE2 epitope that binds to the SARS ... 50 (6): 1513-1529.e9 Abstract. Broadly neutralizing antibodies (bNAbs) against HIV-1 envelope (Env) inform vaccine design and ... titres were less than 50 in 33% of samples, below 1,000 in 79% of samples and only 1% of samples had titres above 5,000. ...
Minimal Inhibitory Concentration) line. We measured the response surface of the wild-type and of all mutants that showed a ... The concentration profile for each drug was set up according to where cmax was the highest concentration used, x was linearly ... of this mutant to drug A at concentration a alone; here, gi(a) and gi(0) denote the growth rate of mutant i in the presence and ... The scaling factors for the drug concentration are then given by and and that for the growth rate is given by γi = gi(0)/gWT(0 ...
The distribution of minimum inhibitory concentrations (MICs) of ceftriaxone forNeisseria gonorrhoeaeisolates (n=193) cultured ... The minimum inhibitory concentration (MIC; mg/L) of ceftriaxone, cefixime, azithromycin, spectinomycin, ciprofloxacin, ...
Working concentration: 1 Tablet per 50 ml extraction solution.. Working solution: Handling. Carefully push the tablet through ... Proprietary mixture of several protease inhibitors with broad inhibitory specificity.. Physical form. Tablets in a glass vial. ... If very high proteolytic activity is present, 2-3 tablets should be used for 50 ml extraction buffer. The tablets can be added ... One cOmplete ULTRA Tablet, EDTA-free is sufficient for a volume of 50 ml extraction solution. cOmplete ULTRA Tablets contain ...
Minimum Inhibitory Concentration Entry term(s). Concentration, Minimum Inhibitory Concentrations, Minimum Inhibitory Inhibitory ... Inhibitory Concentration, Minimum. Inhibitory Concentrations, Minimum. Microbial Sensitivity Test. Minimum Inhibitory ... Concentration, Minimum Inhibitory Concentrations, Minimum Minimum Inhibitory Concentrations Antibiogram - Narrower Concept UI. ... Concentration, Minimum Inhibitory. Concentrations, Minimum Inhibitory. Drug Sensitivity Assay, Microbial. Fungal Drug ...
... inhibitory concentration (IC50) of SLN on two breast cancer cell lines, MCF-7 and MDA-MB231 for 24, 48 and 72 h are presented ... A haemocytometer was used to estimate the concentration of the cells in the flask. At a concentration, One hundred microlitres ... Effect of surfactant concentration on the cytotoxicity of SLN: Toxicity of four formulations of SLN (SLN-03a, SLN-03b, SLN-03c ... The neutral red enters the lysosomes of viable cells and its concentration measured at 540 nm (Fautz et al., 1991). The results ...
Inhibitory Concentration 50, Leukocytes, Mononuclear, Male, Mice, Micronuclei, Chromosome-Defective, Micronucleus Tests, ... mass concentrations from 0.1 to 100 μg/ml) were assessed in murine macrophages RAW 264.7 and in peripheral whole blood from ... mass concentrations from 0.1 to 100 μg/ml) were assessed in murine macrophages RAW 264.7 and in peripheral whole blood from ... mass concentrations from 0.1 to 100 μg/ml) were assessed in murine macrophages RAW 264.7 and in peripheral whole blood from ...
Vitamin C had a median inhibitory concentration (IC50) of 0.038 mg/ml which was lower than IC50 of all the extracts. Of ... 50 mg/kg) at the first three hours but significantly higher (p < 0.05) at the fourth hour. At the fifth hour, the ... Table 3 DPPH Inhibitory Concentration (IC50) of the extracts of Feretia apodanthera. Full size table. ... Vitamin C had a median inhibitory concentration (IC50) of 0.038 mg/ml which was lower than IC50 of all the extracts. Of all the ...
Inhibitory Concentration 50. -. dc.subject. Phosphorylation. -. dc.subject. Drug Resistance, Neoplasm. -. dc.subject. Octamer ... IC50(imatinib) is defined as the in vitro concentration of drug required to reduce phosphorylation of the adaptor protein Crkl ... by 50%. We now show that interpatient variability in IC50(imatinib) is mainly due to differences in the efficiency of imatinib ...
inhibitory concentration (IC). Concentration of a substance that causes a defined inhibition of a given system. Note: IC50 is ... effective concentration (EC). Concentration of a substance that causes a defined magnitude of response in a given system. Note ... EC50 is the median concentration that causes 50 % of maximal response. ... the median concentration that causes 50 % inhibition.. Reference. *Duffus, J. H.; Nordberg, M.; Templeton, D. M. Pure and ...
... inhibitory concentration value for phospholipids to reduce the binding of FVIIa to EPCR was 57 center dot 67 +/- 0 center dot ... In 90% of patients, we found a causative (85% of upper GI bleeding and 50% of lower GI bleeding) or potentially causative ... MethodsOutcomes in a cohort of patients undergoing mostly minor hepatectomy (50 laparoscopic and 52 open surgery procedures) ...
2.2.2.3 Half maximal inhibitory concentration (IC. 50. ) of carboplatin to ALTS1C1 glioma cells ... 2.2.2.3 Half maximal inhibitory concentration (IC50) of carboplatin to ALTS1C1 glioma cells……….18 ... adequate carboplatin concentration for in vivo experiment, we adopted the carboplatin concentration of 2 mg/mL for our in vivo ... After 24 h, 0.02 mL of the concentrated carboplatin solution was poured to each well to accomplish the final concentration ...
inhibition value then converts to inhibitory concentration 50 (IC50) using regression equation (Karim et al., 2014; Wang et al ... The cocoa pod extract has very strong antioxidant activity with inhibitory concentration (IC50) of 17.21 ppm. The extract also ... Percent inhibition of DPPH by the extract was then calculated and converted to inhibitory concentration 50 (IC50) using ... with extract concentration shown at Figure 2. Our study shows that cocoa pod extract has antioxidant and tyrosinase inhibitory ...
... of potentially inhibitory substances and of nitrogen and phosphorus concentrations, which would have limited growth if they ... After 7 months of continuous operation and 50 cycles of water reuse, the algae productivities of the water and nutrient ... A potential difficulty with internal recycling is the accumulation of auto-inhibitory compounds in recycled algae pond water. ... Only salt concentrations showed significant accumulation in the ponds, but not to concentrations expected to be inhibitory. A ...
... inhibitory concentrations of 20 and 95 microg/mL, respectively, which was similar to the effect of butylated hydroxyanisole. ... Aldose Reductase Inhibitory Alkaloids from Corydalis ternata. *Growth inhibition effect of Rubus coreanus Miquel on Candida ... Inhibitory effects of ginseng components on rat lens aldose reductase activities. J Ginseng Res. 1996; 20:106-110. ... Antioxidative and aldose reductase-inhibitory effects of a fermentation filtrate of Rubus coreanus. *Kwon SC ...
... of the inhibitory capacity of NF54-IgG against the homologous parasite indicated that blocking is achieved at IgG concentration ... A single full-length VAR2CSA variant purifies the bulk of naturally acquired binding-inhibitory IgG. Strong cross-inhibitory ... IgG were tested at 0.1 µg/mL concentration. (B) Ability of purified VAR2CSA IgG to bind native VAR2CSA on six CSA-binding ... CSA-binding inhibitory activity of VAR2CSA-specific purified IgG from multigravidae.. The inhibition capacity of VAR2CSA- ...
... inhibitory concentration against wild-type HIV-1) throughout the first week of life. This limited regimen has been shown to be ... Cord blood nevirapine concentrations were below the target concentration of 100 ng/mL (10-times the in vitro IC(50) of ... Steady-state concentrations in plasma were determined on day 12, and single postdose concentrations were measured on days 1, 3 ... Predose infant nevirapine concentrations were below 100 ng/mL in 23 (15%) of 149 infants (95% CI, 10%-22%); the concentrations ...
... and found the n-hexane extract had inhibitory concentration 50 percent (IC50) values of 0.59 and 0.21 mg/mL for AChE and BChE, ... they examined the in vitro antioxidant properties and cholinesterase inhibitory activity of fractions and extracts of Salvia ...
the minimum inhibitory concentration of honey was found to range from 5.5% to 9.0%. In another with 58 clinical isolates of ... the minimum inhibitory concentration of honey was found to range from 2% to 4% (v/v). Antibiotic-resistant strains of bacteria ... It was found that the minimum inhibitory concentrations of honey for Strep. mitis, Strep. sobrinus and Lactobacillus caseii ... also found the minimum inhibitory concentration of honey for Strep. mutans was 25%, and for Strep. sobrinus was 35%, which also ...
... inhibitory area under the concentration curve of 5-fluorouracil obtained with collagen gel droplet-embedded culture-drug ... but can generally provide only semiquantitative data about the concentration of the targets. In settings where such ... Identification of responders/non-responders to 5-fluorouracil based on individual 50% ...
Inhibitory Concentration 50, Male, Mice, Microtubules/metabolism, Prodrugs, Swine, Tubulin/metabolism, Tubulin Modulators, ... At biologically relevant concentrations, LS 4477 and LS 4559 caused a 59.9 and 56% reduction in tubulin assembly, respectively ... At biologically relevant concentrations, LS 4477 and LS 4559 caused a 59.9 and 56% reduction in tubulin assembly, respectively ... At biologically relevant concentrations, LS 4477 and LS 4559 caused a 59.9 and 56% reduction in tubulin assembly, respectively ...
Inhibitory Concentration 50 13% 21 Scopus citations * Postoperative Pain Control and Opioid Usage Patterns among Patients ...
... half maximal inhibitory concentration; ICD: immunogenic cell death; ICP-AES: inductively coupled plasma atomic emission ... Data are presented as mean±SD (n=6); (B) Cellular uptake of Bodipy-DGL/Pt and Bodipy-Wpep-DGL/Pt at different concentrations by ... This suggested that increased intracellular Pt concentration contributed to enhanced activation of native immune cells and the ... Also, the mean fluorescent intensities of Bodipy-Wpep-DGL/Pt exhibited a concentration-dependent tendency. ...
... dimethoxyflavone as a potent antifungal agent was investigated by determining its inhibitory activity on Candida albicans drug ... It showed growth inhibitory activity against C. albicans and C. krusei with minimum inhibitory concentrations of 0.08 and 0.16 ... In brief, different concentrations of test compound were prepared by serial dilution and 20 μl of each concentration was added ... The final concentrations of the test compound in a microtitre plate ranged from 0-90 μg/ml. Miconazole was also added to the ...
The half maximal inhibitory concentration for 5-fluorouracil in BGC-823 cells was elevated after treatment with conditioned ... The half maximal inhibitory concentration of 5-fluorouracil and levels of cell apoptosis were examined using cell viability ... The half maximal inhibitory concentration of 5-fluorouracil and levels of cell apoptosis were examined using cell viability ... The half maximal inhibitory concentration for 5-fluorouracil in BGC-823 cells was elevated after treatment with conditioned ...
LC-HRMS and FTIR-based metabolomics analysis and xanthine oxidase inhibitory evaluation of Sida rhombifolia with different ... The Dependence of Boron Concentration in Diamond Electrode for Ciprofloxacin Electrochemical Sensor Application. Savitri, I. N ... Phytochemical analysis in conjunction with in vitro α-glucosidase inhibitory and antioxidant activities of three Diospyros ... Resveratrol Trimer Together with Other Stilbenoid Compounds from the Lianas of Gnetum microcarpum Blume and Their Inhibitory ...
Drug-entrapped DPPC liposomes were tested at concentrations comparable to their relative minimum inhibitory concentrations (MIC ... The inhibitory effects on cytokine secretion was displayed in a dose-dependent manner as well as a threshold effect that was ... 50%. It was concluded that drug-entrapped DPPC liposomes could fulfill the dual role of pulmonary drug delivery and alveolar ...
It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC ... and SGK, even at concentrations (50 µM). .mainwu{padding:10px;}.imagewu{padding: 20px 0 20px 0;}.titlewu{text-align:center; ...
A dose dependent curve was obtained by plotting concentration of dose and cell viability. These findings promote the discovery ... performed for ethanolic extract of Cannabis sativa at various concentrations of dilutions. In vitro antiproliferative potential ... Minimum inhibitory concentration (MIC) performed for ethanolic extract of Cannabis sativa at various concentrations of ... A dose dependent curve was obtained by plotting concentration of dose and cell viability. These findings promote the discovery ...
The baskets formed by inhibitory basket cells have high concentrations of glutamic acid decarboxylase (GAD), the enzyme that ... The baskets formed by inhibitory basket cells have high concentrations of glutamic acid decarboxylase (GAD), the enzyme that ... Ih demonstrated a mixed Na+-K+ conductance and was sensitive to low concentrations of external CsCl. As a result of Ih the ... Ih demonstrated a mixed Na+-K+ conductance and was sensitive to low concentrations of external CsCl. As a result of Ih the ...