Hypoxia-Inducible Factor 1, alpha SubunitHypoxia-Inducible Factor 1Cell HypoxiaProcollagen-Proline DioxygenaseAnoxiaHypoxia-Inducible Factor-Proline DioxygenasesBasic Helix-Loop-Helix Transcription FactorsVon Hippel-Lindau Tumor Suppressor ProteinAmino Acids, DicarboxylicVascular Endothelial Growth Factor APolycythemiaOxygenAryl Hydrocarbon Receptor Nuclear TranslocatorMimosineCobaltGlucose Transporter Type 1HydroxylationTranscription FactorsDeferoxamineCell Line, TumorRNA, MessengerCarbonic AnhydrasesNeovascularization, PathologicGene Expression RegulationSignal TransductionUp-RegulationCarcinoma, Renal CellReverse Transcriptase Polymerase Chain ReactionKidney NeoplasmsGene Expression Regulation, NeoplasticImmunohistochemistryRNA, Small InterferingBlotting, WesternTranscriptional ActivationReactive Oxygen SpeciesNuclear ProteinsHypoxia, BrainCell LineCells, CulturedGlycolysisDNA-Binding ProteinsRNA InterferenceApoptosisPromoter Regions, GeneticCell SurvivalCell ProliferationNeoplasmsTumor Suppressor ProteinsDown-RegulationFetal HypoxiaReal-Time Polymerase Chain ReactionTranscription, GeneticMice, Inbred C57BLTransfectionGene Expression ProfilingRats, Sprague-DawleyModels, BiologicalProtein BindingMutationErythropoietinBase SequenceUbiquitin-Protein LigasesMolecular Sequence DataTrans-ActivatorsAltitudeTime FactorsTumor Cells, CulturedOxidative StressMitochondriaNitroimidazolesChemoreceptor CellsCell NucleusNF-kappa BGene ExpressionHypercapniaEtanidazoleDose-Response Relationship, DrugPulmonary ArteryRespirationAntineoplastic AgentsAltitude SicknessRecombinant ProteinsCarbon DioxideMisonidazolePartial PressureOxygen Consumption