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*  Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. - Physiology,...
Congenital hyperinsulinism caused by glucokinase mutations (GCK-CHI) is associated with β cell replication and apoptosis. Here ... Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. ... Congenital hyperinsulinism caused by glucokinase mutations (GCK-CHI) is associated with β cell replication and apoptosis. Here ... Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. ...
https://www.dpag.ox.ac.uk/publications/444278
*  Persistent Hyperinsulinemic Hypoglycemia | SpringerLink
Stanley CA (1997) Hyperinsulinism in infants and children. Pediatr Clin North Am 44:363-374PubMedCrossRefGoogle Scholar ... de Lonlay-Debeney P, Poggi-Travert F, Fournet JC et al (1999) Clinical aspects and course of neonatal hyperinsulinism. N Engl J ... Glaser B, Kesavan P, Heyman M et al (1998) Familial hyperinsulinism caused by an activating glucokinase mutation. N Engl J Med ... Hyperinsulinism can occur throughout childhood but is most common in infancy. Persistent hyperinsulinemic hypoglycemia of ...
https://link.springer.com/chapter/10.1007%2F978-3-540-28785-8_10
*  Congenital disorder of glycosylation - Wikipedia
Three subtypes of CDG I (a,b,d) can cause congenital hyperinsulinism with hyperinsulinemic hypoglycemia in infancy. A ...
https://en.wikipedia.org/wiki/Congenital_disorder_of_glycosylation
*  Hyperinsulinism: Background, Pathophysiology, Epidemiology
Primary hyperinsulinism is a rare but important cause of hypoglycemia in infants and children. It is the most common cause of ... encoded search term (Hyperinsulinism) and Hyperinsulinism What to Read Next on Medscape. Medscape Consult. ... Several genetic causes of persistent hyperinsulinism have been identified. [2, 3, 4, 5, 6, 7, 8, 9, 10] See the image below. ... Primary hyperinsulinism is a rare but important cause of hypoglycemia in infants and children. It is the most common cause of ...
https://emedicine.medscape.com/article/921258-overview
*  Hyperinsulinism? - BabyCenter
Josie will be 8 weeks old tomorrow and today she was diagnosed with hyperinsulinism. She's had a hard time regulating her blood ... Josie will be 8 weeks old tomorrow and today she was diagnosed with hyperinsulinism. She's had a hard time regulating her blood ...
https://community.babycenter.com/post/a67575622/hyperinsulinism
*  Familial focal congenital hyperinsulinism. - PubMed - NCBI
Familial focal congenital hyperinsulinism.. Ismail D1, Smith VV, de Lonlay P, Ribeiro MJ, Rahier J, Blankenstein O, Flanagan SE ... Congenital hyperinsulinism (CHI) is a cause of persistent hypoglycemia. Histologically, there are two subgroups, diffuse and ...
https://www.ncbi.nlm.nih.gov/pubmed/20943779
*  Surgery for Congenital Hyperinsulinism | SpringerLink
Our multidisciplinary approach to patients with congenital hyperinsulinism can distinguish focal from diffuse disease, localize ... Characterization of hyperinsulinism in infancy assessed with PET and 18F-fluoro-L-DOPA. J Nucl Med. 2005;46:560-6.PubMedGoogle ... Congenital hyperinsulinism and the surgeon: lessons learned over 35 years. J Pediatr Surg. 1999;34:786-92.CrossRefGoogle ... Accuracy of PET/CT scan in the diagnosis of the focal form of congenital hyperinsulinism. J Pediatr Surg. 2013a;48:388-93. ...
https://link.springer.com/chapter/10.1007%2F978-3-030-02961-6_9
*  Hyperinsulinism Due to Islet-cell Adenoma | The BMJ
Hyperinsulinism Due to Islet-cell Adenoma Br Med J 1949; 1 :680 ... Hyperinsulinism Due to.... *Hyperinsulinism Due to Islet-cell ... Hyperinsulinism Due to Islet-cell Adenoma. Br Med J 1949; 1 doi: https://doi.org/10.1136/bmj.1.4606.680-a (Published 16 April ...
http://www.bmj.com/content/1/4606/680.2
*  Hyperinsulinism | CTD
Hyperinsulinism Synonyms Compensatory Hyperinsulinemia , Endogenous Hyperinsulinism , Exogenous Hyperinsulinism , ... Hyperinsulinemia , Hyperinsulinemia, Compensatory , Hyperinsulinism, Endogenous , Hyperinsulinism, Exogenous Definition A ... Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin ...
http://ctd.mdibl.org/detail.go?type=disease&acc=MESH%3AD006946
*  Sandostatine® LP and Hyperinsulinism - Tabular View - ClinicalTrials.gov
Sandostatine® LP and Hyperinsulinism. The safety and scientific validity of this study is the responsibility of the study ... Sandostatine® LP and Hyperinsulinism. Official Title ICMJE Replace Sandostatine® in Three Daily Subcutaneous Injections by a ... Congenital Hyperinsulinism. Intervention ICMJE Drug: Sandostatine LP Intramuscular injection of Sandostatine LP, once per month ... Ten children who have a diffuse form of hyperinsulinism have been treated in our department by Sandostatine® given in three ...
https://clinicaltrials.gov/ct2/show/record/NCT00987168
*  Hyperinsulinism - Renal and Urology News
Surgery for diffuse hyperinsulinism carries a risk of diabetes. Surgery for focal hyperinsulinism in experienced centers should ... Hyperinsulinism is the most common hypoglycemic disorder in infants and neonates. Transient neonatal hyperinsulinism is common ... Diazoxide is the drug of choice for long-term management of hyperinsulinism. Once a diagnosis of hyperinsulinism has been made ... In cases of focal hyperinsulinism, surgical resection can be curative. Near-total pancreatectomy for diffuse hyperinsulinism ...
https://www.renalandurologynews.com/pediatrics/hyperinsulinism/article/620276/
*  Hyperinsulinism | Svensk MeSH
Hyperinsulinism. Hyperinsulinism. Svensk definition. Ett syndrom med onormalt höga insulinhalter i blodet. Det kan ge upphov ... Hyperinsulinemia - Exogenous Hyperinsulinism - Hyperinsulinism, Exogenous - Compensatory Hyperinsulinemia - Hyperinsulinemia, ... Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin ...
https://mesh.kib.ki.se/term/D006946
*  Hyperinsulinism - Hyperinsulinemia Summary Report | CureHunter
Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin ... Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. ... Exogenous Hyperinsulinism; Hyperinsulinemia, Compensatory; Hyperinsulinism, Endogenous; Hyperinsulinism, Exogenous ... Hyperinsulinism (Hyperinsulinemia). Subscribe to New Research on Hyperinsulinism A syndrome with excessively high INSULIN ...
http://www.curehunter.com/public/keywordSummaryD006946-Hyperinsulinism-Hyperinsulinemia.do
*  Hyperinsulinism assessment in a sample of prepubescent children
CONCLUSIONS: The results of this study allow for the conclusion that there is a strong association between hyperinsulinism and ... Hyperinsulinism assessment in a sample of prepubescent children. J Pediatr (Rio J). 2010;86(3):245-249. ... In children and adolescents, obesity generally precedes the appearance of hyperinsulinism,22 which is considered an independent ... Ergo, obese children have greater chances of developing hyperinsulinism and so certain preventative measures are required to ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572010000300014&lng=en&nrm=iso&tlng=en
*  Hyperinsulinism / Hyperammonemia Syndrome: Natalie's Story | Children's Hospital of Philadelphia
Natalie traveled to Philadelphia for specialized treatment at CHOP's Congenital Hyperinsulinism Center. ... From the first days of Natalie's diagnosis of hyperinsulinism/hyperammonemia (HI/HA) syndrome, her doctors back in Orange ... they had benefited from the expertise of the Congenital Hyperinsulinism Center. ... County, CA, had conferred frequently with CHOP doctors at the Congenital Hyperinsulinism Center, and read articles from CHOP ...
https://www.chop.edu/stories/hyperinsulinism-hyperammonemia-syndrome-natalies-story
*  Brandon infant receives lifesaving care for hyperinsulinism | tbo.com
Brandon infant receives lifesaving care for hyperinsulinism. Jonathan Baron soothes his baby Colton Robert Baron with kisses ... Colton was diagnosed with congenital hyperinsulinism, a rare group of disorders in which the body produces too much insulin, ... 31 by air ambulance to the Congenital Hyperinsulinism Center at the Children's Hospital in Philadelphia, one of the few places ... worldwide that specialize in identifying various types of hyperinsulinism and performing corrective surgery. ...
http://www.tbo.com/brandon/brandon-infant-receives-lifesaving-care-for-hyperinsulinism-20140210/
*  Perioperative Management of Hyperinsulinism | Springer for Research & Development
The care of children undergoing pancreatectomies for hyperinsulinism presents unique challenges. In addition to ensuring ... Hyperinsulinism in the neonate. Clin Perinatol. 2018;45(1):61-74.CrossRefGoogle Scholar ... Congenital hyperinsulinism - a review of the disorder and a discussion of the anesthesia management. Paediatr Anaesth. 2007;17( ... In: De León-Crutchlow D., Stanley C. (eds) Congenital Hyperinsulinism. Contemporary Endocrinology. Humana Press, Cham. * First ...
https://rd.springer.com/chapter/10.1007%2F978-3-030-02961-6_10
*  Hyperinsulinism - Wikipedia
Hyperinsulinism refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and ... Hyperinsulinism can be associated with several types of medical problems, which can be roughly divided into two broad and ... Hyperinsulinism due to reduced insulin sensitivity is usually asymptomatic. In contrast, hyperinsulinemic hypoglycemia can ...
https://en.wikipedia.org/wiki/Hyperinsulinism
*  Pioneers in Hyperinsulinism: Yesterday, Today and Tomorrow | Children's Hospital of Philadelphia
CHOP's groundbreaking expertise in treating children with congenital hyperinsulinism (HI) began more than 50 years ago and ... What is hyperinsulinism?. When a baby has HI, the beta cells in their pancreas - a glandular organ about the size of your ... Pioneers in Hyperinsulinism: Yesterday, Today and Tomorrow. Published on Sep 18, 2018 in Breakthrough Report ... Our Congenital Hyperinsulinism Center, which is celebrating its 20-year anniversary this year, treats more HI patients than ...
https://www.chop.edu/news/pioneers-hyperinsulinism-yesterday-today-and-tomorrow
*  Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism - Full Text View - ClinicalTrials.gov
Congenital Hyperinsulinism Hyperinsulinism Persistent Hyperinsulinemic Hypoglycemia of Infancy CHI PHHI Drug: F-DOPA Radiation ... Congenital Hyperinsulinism. Hyperinsulinism. Persistent Hyperinsulinemic Hypoglycemia of Infancy. CHI. PHHI. F-DOPA. L-fluoro- ... Children diagnosed with hyperinsulinism who have had partial pancreas removal but still display signs of hyperinsulinism. ... Hyperinsulinism. Congenital Hyperinsulinism. Hypoglycemia. Glucose Metabolism Disorders. Metabolic Diseases. Pancreatic ...
https://clinicaltrials.gov/ct2/show/NCT00674440?cond=Hyperinsulinism&rank=1
*  Congenital hyperinsulinism - Wikipedia
A GIR above 8 mg/kg/minute in infancy suggests hyperinsulinism. A third form of evidence suggesting hyperinsulinism is a rise ... Diffuse hyperinsulinism FHI-KATP FHI-HADH FHI-UCP2 FHI-HNF4A Glucokinase mutation Hyperammonemic hyperinsulinism (glutamate ... Congenital hyperinsulinism is a medical term referring to a variety of congenital disorders in which hypoglycemia is caused by ... update 2013 "Familial hyperinsulinism , Genetic and Rare Diseases Information Center(GARD) - an NCATS Program". rarediseases. ...
https://en.wikipedia.org/wiki/Congenital_hyperinsulinism
*  Bundesverband Kinderhospiz e.V. - Anastassia's Story - Hope and Hyperinsulinism
Schloss-Urach-Str. 4 · 79853 Lenzkirch · Telefon: +49(0)7653 82 64 00 · Fax: +49(0)7653 8 26 40 18 · info@bundesverband-kinderhospiz.de ...
http://bundesverband-kinderhospiz.de/little-stars/660-anastassias-story
*  Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells | Herb News
Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells. By Teresa Koby on September 28, 2010 ... In the current study, we tested the hypothesis that Ginkgo biloba extract (GBE) prevented hyperinsulinism-induced glucose ...
http://www.herbs.org/herbnews/2010/09/ginkgo-biloba-extract-enhances-glucose-tolerance-in-hyperinsulinism-induced-hepatic-cells/
*  Hyperinsulinism hyperammonemia syndrome - Wikipedia
Hyperinsulinism hyperammonemia syndrome (HI/HA or HHS), is an autosomal dominant disorder that results in the excess production ... "Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel ...
https://en.wikipedia.org/wiki/Hyperinsulinism_hyperammonemia_syndrome