However, the role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which catalyzes the conversion of inactive cortisone ... "11β-Hydroxysteroid dehydrogenase type 1 amplifies inflammation in LPS-induced THP-1 cells". Iranian Journal of Basic Medical ... 11 Beta-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages. J Immunol 2001; ... 11beta-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in ...
Hydroxysteroid Dehydrogenases / antagonists & inhibitors* * Hypophysectomy * Prolactin / pharmacology* * Rats * Time Factors ...
Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure. J Bone Miner ... 11beta-Hydroxysteroid dehydrogenase: a regulator of glucocorticoid response in osteoporosis. J Endocrinol Invest. 2008;31:16-21 ... Expression and functional consequences of 11beta-hydroxysteroid dehydrogenase activity in human bone. Bone. 2000;27:375-81 ... 11beta-Hydroxysteroid dehydrogenase type 1 selective inhibitor BVT.2733 protects osteoblasts against endogenous glucocorticoid ...
17b-hydroxysteroid dehydrogenase (HSD) is a steroidogenic enzyme essential for invertebrate spermatogenesis. A homologue of HSD ... 17b-hydroxysteroid dehydrogenase (HSD) is a steroidogenic enzyme essential for invertebrate spermatogenesis. A homologue of HSD ... EST Cloning and Expression of 17β-Hydroxysteroid Dehydrogenase in the Ascidian, Ciona intestinalis Testis. Kang Hee Kho ... EST Cloning and Expression of 17β-Hydroxysteroid Dehydrogenase in the Ascidian, Ciona intestinalis Testis. Kang Hee Kho ...
We speculate that hexose-6-phosphate dehydrogenase activity and therefore reduced nicotinamide-adenine dinucleotide phosphate ... 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) interconverts inactive cortisone and active cortisol. Although ... by intronic mutations in HSD11B1 that decrease gene transcription together with mutations in hexose-6-phosphate dehydrogenase, ... 11-beta-Hydroxysteroid Dehydrogenase Type 1, Amino Acid Sequence, Animals, Carbohydrate Dehydrogenases, Cloning, Molecular, ...
Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with ...
3-beta-hydroxysteroid dehydrogenase deficiency. *3-beta-hydroxysteroid dehydrogenase deficiency, see 3-beta-hydroxysteroid ... 3b-hydroxysteroid dehydrogenase deficiency, see 3-beta-hydroxysteroid dehydrogenase deficiency. *3beta-HSDH deficiency, see ... 17-beta hydroxysteroid dehydrogenase 3 deficiency. *17-beta hydroxysteroid dehydrogenase III deficiency, see 17-beta ... 3β-hydroxysteroid dehydrogenase deficiency, see 3-beta-hydroxysteroid dehydrogenase deficiency. *4 alpha aminobutyrate ...
Hydroxysteroid 11-beta dehydrogenase (HSD11B) isoenzymes regulate which ligand will bind to MR. In this study we aimed to ... Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 ( ... Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid ...
11β-hydroxysteroid dehydrogenase type 2; pregnancy; asthma; placental function; inhaled glucocorticoid treatment; fetal ... Reduced 11β-hydroxysteroid dehydrogenase type 2 activity is associated with decreased birth weight centile in pregnancies ... Reduced 11β-hydroxysteroid dehydrogenase type 2 activity is associated with decreased birth weight centile in pregnancies ... To investigate whether impaired placental function may be a determinant, we measured placental 11β-hydroxysteroid dehydrogenase ...
Increased expression of 11β-hydroxysteroid dehydrogenase type 1 contributes to epidermal permeability barrier dysfunction in ... Increased expression of 11β-hydroxysteroid dehydrogenase type 1 contributes to epidermal permeability barrier dysfunction in ...
There are two such repeat elements in the HSD11B2 (11β-hydroxysteroid dehydrogenase) gene. First, a CA repeat is located in the ... There are two such repeat elements in the HSD11B2 (11β-hydroxysteroid dehydrogenase) gene. First, a CA repeat is located in the ... There are two such repeat elements in the HSD11B2 (11β-hydroxysteroid dehydrogenase) gene. First, a CA repeat is located in the ... There are two such repeat elements in the HSD11B2 (11β-hydroxysteroid dehydrogenase) gene. First, a CA repeat is located in the ...
MSMEG_2566 MSMEG_2566 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase (EC 1.1.1.53). Mycobacterium smegmatis (strain ATCC ...
Context: Deficiency of 3β-hydroxysteroid dehydrogenase 2 (3βHSD2) causes a very rare form of congenital adrenal hyperplasia ( ... of Molecular Characteristics and Steroid Metabolomics in a Large Cohort of Children with 3β-Hydroxysteroid Dehydrogenase 2 ... Evaluation of Molecular Characteristics and Steroid Metabolomics in a Large Cohort of Children with 3β-Hydroxysteroid ... Evaluation of Molecular Characteristics and Steroid Metabolomics in a Large Cohort of Children with 3β-Hydroxysteroid ...
keywords = "11β-Hydroxysteroid dehydrogenases, Aldosterone, Hypertension, Renin-angiotensin system",. author = "{Mosso G}, ... 11β-hydroxysteroid dehydrogenase activity in patients with hypertension and low plasma renin activity. ... 11β-hydroxysteroid dehydrogenase activity in patients with hypertension and low plasma renin activity. ... Dive into the research topics of 11β-hydroxysteroid dehydrogenase activity in patients with hypertension and low plasma renin ...
17beta-hydroxysteroid dehydrogenases (17beta-HSDs) catalyse the pre-receptor activation/inactivation of hormones and other ... 17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast ... 17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast ... 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) catalyse the pre-receptor activation/inactivation of hormones and other ...
3-β hydroxysteroid dehydrogenase/isomerase. Steroid metabolism. 17. (26). group_273. Recombinase/resolvase. Mobile genetic ... NADH-dependent dehydrogenase. Putative functions. 26. NA. nmrA. Putative nmrA negative transcriptional regulator family protein ...
17beta-hydroxysteroid dehydrogenase type 5 (17β-HSD5) is an important enzyme associated with sex steroid metabolism in hormone- ... 17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein ... Type 5 of 17β-hydroxysteroid dehydrogenase, encoded by the AKR1C3 gene, plays a pivotal role in both androgen and estrogen ... androsterone dehydrogenase (A-specific) activity - androsterone dehydrogenase activity - cellular response to cadmium ion - ...
Regulation und Funktion des Enzyms 11beta-Hydroxysteroid-Dehydrogenase Typ 1 im Skelettmuskelmetabolismus. Views. ...
Porcine 11beta-Hydroxysteroid Dehydrogenase 2 ELISA Kit , MBS004907 , MyBiosourceProduct Short Name: [11beta-Hydroxysteroid ... MBS9932940 , Rat NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 4-Like 2 (NDUFA4L2) ELISA Kit MyBiosource Elisa ... Rat NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 4-Like 2 (NDUFA4L2) ELISA Kit , MBS9932940 , MybiosourceProduct ...
However, within key metabolic target tissues, the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts the ... Effects of glucocorticoids on fat mass and the therapeutic potential of targeting IIβ-hydroxysteroid dehydrogenase type I in ... Effects of glucocorticoids on fat mass and the therapeutic potential of targeting IIβ-hydroxysteroid dehydrogenase type I in ... However, within key metabolic target tissues, the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts the ...
3-Beta-Hydroxysteroid Dehydrogenase Deficiency. * Acromegaly. * Adrenocortical (Adrenal Cortical) Carcinoma Imaging. * ...
11β-hydroxysteroid dehydrogenases: A growing multi-tasking family[J]. Mol Cell Endocrinol, 2021, 526: 111210. doi: 10.1016/j. ... 11β-hydroxysteroid dehydrogenase type 1 inhibitor attenuates high-fat diet induced cardiomyopathy[J]. J Mol Cell Cardiol, 2018 ... 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), encoded by Hsd11b1, is a reductase that can convert inactive cortisone into ... Shao S, Zhang X, Zhang M. Inhibition of 11β-hydroxysteroid dehydrogenase type 1 ameliorates obesity-related insulin resistance[ ...
Cyclopentanone Acts as a Selective 11β-Hydroxysteroid Dehydrogenase one Inhibitor to Treat Diet-Induced Nonalcoholic Fatty ... 11b-hydroxysteroid dehydrogenase 211b-hydroxysteroid dehydrogenase 1 inhibitorcyclopentanone derivativesnonalcoholic fatty ... Background: 11β-Hydroxysteroid dehydrogenase one is responsible for activating inert glucocorticoid cortisone into biologically ... Results: WZS08 was the most potent inhibitor of rat, mouse, and human 11β-hydroxysteroid dehydrogenase 1, with half maximum ...
Avhandlingar om SHORT-CHAIN DEHYDROGENASES REDUCTASES. Sök bland 109744 avhandlingar från svenska högskolor och universitet på ... 3 beta 17 beta-hydroxysteroid dehydrogenase; 17 beta-hydroxysteroid dehydrogenase; short chain hydroxyacyl coenzyme A ... 3. Short-chain dehydrogenases/reductases : structure, function and motifs of hydroxysteroid dehydrogenases. Författare : ... Short-chain dehydrogenases reductases. . *. 1. Short-chain retinol dehydrogenases/reductases : Involvement in retinoid ...
3-beta-hydroxysteroid dehydrogenase [3-beta-HSD]; CYP11A1; CYP17A1; 17-beta-hydroxysteroid dehydrogenase [17-beta-HSD]), and ...
11β-hydroxysteroid dehydrogenases: common lessons from rare mutations. Stewart Paul In mammalian tissues, two isozymes of 11β- ... hydroxysteroid dehydrogenase (11β-HSD) catalyze the interconversion of hormonally active cortisol (F) and inactive cortisone (E ... 11β-HSD2 is a high affinity dehydrogenase expressed in adult kidney that inactivates F to E protecting the mineralocorticoid ...
17-beta-hydroxysteroid dehydrogenase X (HSD10) deficiency: HSD17B10* , MetaboSeq , Test Requisition. *Acyl-CoA Dehydrogenase-9 ... Short-chain acyl-CoA dehydrogenase (SCAD) deficiency: ACADS* , MetaboSeq , Test Requisition. *Very-long-chain acyl-CoA ... Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: ACADM , MetaboSeq , Test Requisition. *Multiple Acyl-CoA Dehydrogenation ... Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency: HADHA , HADHB* , MetaboSeq , Test Requisition ...
to synthesize testosterone, among which the 3β-hydroxysteroid dehydrogenase (3β-HSD) is considered the most important[60]. The ... Characterization of rat 3 beta-hydroxysteroid dehydrogenase/delta. 5-delta 4 isomerase cDNAs and differential tissue-specific ...
17-β-Hydroxysteroid dehydrogenase type 3 (17βHSD-3) is present almost exclusively in the testes, and converts androstenedione ( ... 17p-Hydroxysteroid dehydrogenase type 3 deficiency as a result of a homozygous 7 base pair deletion in 17βHSD3 gene. J Pedialr ... 17-β-hydroxysteroid dehydrogenase 3 deficiency. Trends Endocrinol Metab 1996;7:121-6.10.1016/1043-2760(96)00034-3Search in ... 17-β-Hydroxysteroid dehydrogenase type 3 (17βHSD-3) is present almost exclusively in the testes, and converts androstenedione ( ...
3α-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni. View Price and Availability. Roche ...