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Association of SULT1A1 Phenotype and Genotype with Prostate Cancer Risk in African-Americans and Caucasians | Cancer...
The first step involves hydroxylation catalyzed by cytochrome P4501A2 in human liver. Subsequent metabolism of the N- hydroxy ...
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PredHydroxy: computational prediction of protein hydroxylation site locations based on the primary structure . Mol BioSyst 2015 ... hydroxylation and so on. So, amino acid variations that occur on the adjacent positions of lysine methylation site may change ... PredHydroxy: computational prediction of protein hydroxylation site locations based on the primary structure . Mol BioSyst 2015 ... PredHydroxy: computational prediction of protein hydroxylation site locations based on the primary structure . Mol BioSyst 2015 ...
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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 2001; ... Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 2001; 292 ...
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Conformation in Lysine Monooxygenase NbtG Provides Insights Into Uncoupling of Oxygen Consumption From Substrate Hydroxylation. ... of 3-hydroxybenzoate 6-hydroxylase uncovers lipid-assisted flavoprotein strategy for regioselective aromatic hydroxylation.. J ...
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aromatic and aliphatic hydroxylations. *dealkylations at nitrogen, sulphur, and oxygen atoms. *heteroatom oxidations at ...
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At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an ... "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." in: Genes & ...
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Decoupling the roles of carbon and metal oxides on the electrocatalytic reduction of oxygen on La1-xSrxCoO3-δ perovskite...
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Briviba, K., Devasagayam, T. P. A., Sies, H., Steenken, S. (1993). Selective para hydroxylation of phenol and aniline by ...
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Midazolam hydroxylation by human liver microsomes in vitro: inhibition by flouxetine, norfluoxetine, and by azole antifungal ... depends on conjugation rather than hydroxylation, and this it is not inhibited by nefazodone (personal communication, Roche ...
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The drug is metabolized by aromatic hydroxylation, N-dealkylation, and deamination, primarily in the liver. For the most part, ...
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A 90:10 atmosphere of carbon monoxide and oxygen did not appreciably block the 7 alpha-hydroxylation of testosterone by ... Testicular microsomes from mature, but not immature, rats catalyzed the 7 alpha-hydroxylation of testosterone. Previous studies ... Antibody against cytochrome P-450h completely inhibited (greater than 95%) the 2 alpha- and 16 alpha-hydroxylation of ... and 16 beta-hydroxylation of testosterone catalyzed by lung microsomes (as did carbon monoxide and antibody against NADPH- ...
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The PHDs are 2-oxoglutarate (2OG)-dependent dioxygenases that catalyse trans-4-prolyl hydroxylation of the hypoxia-inducible ... confirm the stereoselectivity of the hydroxylation, and identify a gate keeper residue in PHD2. ... factors (HIFs). Prolyl-hydroxylation enables the proteasomal degradation of HIF, causing the suppression of the hypoxic ...