Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer - Full Text View - ClinicalTrials...  Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer - Full Text View - ClinicalTrials...
Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer. This study has been terminated. ... Suberoylanilide hydroxamic acid may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth ... Drugs used in chemotherapy, such as suberoylanilide hydroxamic acid, work in different ways to stop the growth of tumor cells, ... Patients receive oral suberoylanilide hydroxamic acid twice daily on days 1-14. Courses repeat every 21 days in the absence of ...
more infohttps://clinicaltrials.gov/ct2/show/NCT00132002?cond=%22Breast+cancer+male%22&rank=7
METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID - DrugBank  METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID - DrugBank
Alpha amino acid amides / Amphetamines and derivatives / N-acyl amines / Secondary carboxylic acid amides / Hydroxamic acids / ... Organic acids and derivatives. Class. Carboxylic acids and derivatives. Sub Class. Amino acids, peptides, and analogues. Direct ... Carboxamide groupSecondary carboxylic acid amide / Hydroxamic acid / Organic nitrogen compound / Organonitrogen compound / ... METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID. Accession Number. DB08403. Type. Small Molecule. Groups. Experimental. ...
more infohttps://www.drugbank.ca/drugs/DB08403
The Rearrangement of Hydroxamic Acids Isomeric with Triphenyl-acethydroxamic ... - Frank Brian Root - Google Books  The Rearrangement of Hydroxamic Acids Isomeric with Triphenyl-acethydroxamic ... - Frank Brian Root - Google Books
acetyl acid chloride acid showed acid was dissolved acid was treated alcoholic solution alkali amine hydrochloride ammonia Anal ... Hydroxamic acids - 17 pages. 0 Reviewshttps://books.google.com/books/about/The_Rearrangement_of_Hydroxamic_Acids_Is.html?id= ... Acids_Is.html?id=wBpDAAAAIAAJ&utm_source=gb-gplus-shareThe Rearrangement of Hydroxamic Acids Isomeric with Triphenyl- ... ether solution ferric chloride Found free radical gave hydrochloric acid hydrogen chloride hydrolyzed Hydroxamic Acids Derived ...
more infohttps://books.google.com/books?id=wBpDAAAAIAAJ&q=benzhydryl-benzhydroxamic+acid&dq=related:OCLC10655760&source=gbs_word_cloud_r&hl=en
Gold(I)-catalyzed heterocyclization of β-alkynyl hydroxamic acids: synthesis of isoxazolidin-3-ones | SpringerLink  Gold(I)-catalyzed heterocyclization of β-alkynyl hydroxamic acids: synthesis of isoxazolidin-3-ones | SpringerLink
... exo cyclization of N-substituted α-alkynyl hydroxamic acids into isoxazolidin-3-ones catalyzed by Au(PPh3)SbF6was developed. ... A practical and mild method for the 5-exo cyclization of N-substituted α-alkynyl hydroxamic acids into isoxazolidin-3-ones ... Isoxazolidin-3-ones Heterocycles Catalysis Cyclizations Hydroxamic acid Electronic supplementary material. The online version ... Chang JH (1983) Herbicidal 3-isoxazolidinones ans hydroxamic acids. US Patent 4,405,357, Sep 20, 1983; (1984). Chem Abstr 100: ...
more infohttps://link.springer.com/article/10.1007/s00706-014-1319-1
Patent US6696477 - Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and ... - Google Patents  Patent US6696477 - Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and ... - Google Patents
Hydroxamic acid derivative and medicine containing the same as active ingredient. US20060106014 *. Oct 13, 2005. May 18, 2006. ... Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient. US20080161324 *. Sep 13, 2007. Jul 3, 2008. ... 5-dihydroimidazoles 31 may be dehydrated in the presence of an acid catalyst such as 4-toluenesulfonic acid or mineral acids to ... Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors. US 6696477 B2 ...
more infohttp://www.google.com/patents/US6696477?dq=6480844
Molecules | Free Full-Text | Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas  Molecules | Free Full-Text | Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas
A series of hydroxyurea derivatives of L- and D-amino acid amides and cycloalkyl-N-aryl-hydroxamic acids was synthesized and ... In addition, the investigated compounds, especially hydroxamic acids, were proven to be excellent antioxidants. They were as ... most of the investigated hydroxamic acids were stronger Fe2+ ion chelators than quercetin. ... effective as BHA in inhibiting b-carotene-linoleic acid coupled oxidation. It is reasonable to assume that the antioxidant ...
more infohttp://www.mdpi.com/1420-3049/16/8/6232
Efficient Route to Highly Water-Soluble Aromatic Cyclic Hydroxamic Acid Ligands - Digital Library  Efficient Route to Highly Water-Soluble Aromatic Cyclic Hydroxamic Acid Ligands - Digital Library
As a useful derivative, the highly water-soluble sulfonic acid has been synthesized by an efficient route that allows general ... access to 1,2-HOQIO 3-carboxlic acid amides, which are the most relevant for applications. ... is a new member of the important class of aromatic cyclic hydroxamic acid ligands which are widely used in metal sequestering ... Seitz, Michael & Raymond, Kenneth N. Efficient Route to Highly Water-Soluble Aromatic Cyclic Hydroxamic Acid Ligands, article, ...
more infohttps://digital.library.unt.edu/ark:/67531/metadc932907/
3D View 









- 1EBV: OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID 3D View Report Page  3D View - 1EBV: OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID 3D View Report Page
O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional ... ACETIC ACID SALICYLOYL-AMINO-ESTER. C9 H9 N O4. 195.172 Click on icon image highlight macromolecule to ligand interaction in ...
more infohttps://www.rcsb.org/pdb/explore/jmol.do?bionumber=1&structureId=1EBV
Hydroxamic acid - Wikipedia  Hydroxamic acid - Wikipedia
Ligands derived from hydroxamic acid and thiohydroxamic acid also form strong complexes with lead(II). Hydroxamic acids are ... MeOH Hydroxamic acids can also be synthesized from aldehydes via the Angeli-Rimini reaction. A well-known hydroxamic acid ... Hydroxamic acids are usually prepared from either esters or acid chlorides by a reaction with hydroxylamine salts. For the ... Sample gallery Ferrichrome Deferoxamine Rhodotorulic acid In the area of coordination chemistry, hydroxamic acids are excellent ...
more infohttps://en.wikipedia.org/wiki/Hydroxamic_acid
Squaric acid N-hydroxylamides: synthesis, structure, and properties of vinylogous hydroxamic acid analogues.  Squaric acid N-hydroxylamides: synthesis, structure, and properties of vinylogous hydroxamic acid analogues.
These derivatives are analogues of the naturally occurring iron(III) chelator hydroxamic acid. On the basis of a comparative ... The synthesis of squaric acid N-hydroxylamide esters 5 and amides 6 from dimethyl squarate 2a is described. ... 0/Cyclobutanes; 0/Ferric Compounds; 0/Hydroxamic Acids; 0/Hydroxylamines; 0/Vinyl Compounds; 2892-51-5/squaric acid ... Hydroxamic Acids / chemical synthesis*, chemistry. Hydroxylamines / chemistry*. Magnetic Resonance Spectroscopy. Models, ...
more infohttp://www.biomedsearch.com/nih/Squaric-acid-N-hydroxylamides-synthesis/14629141.html
Suberoylanilide hydroxamic acid enhances chemosensitivity to 5-fluorouracil in hepatocellular carcinoma via inhibition of...  Suberoylanilide hydroxamic acid enhances chemosensitivity to 5-fluorouracil in hepatocellular carcinoma via inhibition of...
Here, we investigated the effect of combination treatment with suberoylanilide hydroxamic acid (SAHA) and... ... Hepatocellular carcinoma Suberoylanilide hydroxamic acid 5-fluorouracil Combination Thymidylate synthase This is a preview of ... Suberoylanilide hydroxamic acid enhances chemosensitivity to 5-fluorouracil in hepatocellular carcinoma via inhibition of ... Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood ...
more infohttps://link.springer.com/article/10.1007/s13277-015-3497-9
Amino acid-derived amides and hydroxamic acids as ligands for asymmetric transfer hydrogenation in aqueous media  Amino acid-derived amides and hydroxamic acids as ligands for asymmetric transfer hydrogenation in aqueous media
Amides and hydroxamic acids derived from α-amino acids were evaluated as ligands in combination with rhodium and iridium half- ... Amino acid-derived amides and hydroxamic acids as ligands for asymmetric transfer hydrogenation in aqueous media. Ahlford, ... where it is found that amino acid-derived hydroxamic acids and thioamides, respectively, are simple and versatile ligands that ... The applicability of hydroxamic acid ligands is further extended, and catalysts based on these compounds are found to be ...
more infohttp://www.diva-portal.org/smash/record.jsf?dswid=-6003&pid=diva2%3A405211&c=18&searchType=SIMPLE&language=en&query=&af=%5B%22hasFulltext%3Afalse%22%5D&aq=%5B%5B%7B%22organisationId%22%3A%22631%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
US Patent # 8,143,423. N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids - Patents.com  US Patent # 8,143,423. N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids - Patents.com
A process for preparing hydroxamic acids is provided. The process comprises reacting an aldehyde with a nitroso compound in the ... C. Hydroxamic Acid In an embodiment of the present invention, the hydroxamic acid may be, for example, and without limitation, ... N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids Abstract. A process for preparing hydroxamic acids is ... F. Process for Preparing Chiral Hydroxamic Acid The above process for preparing the hydroxamic acid may be modified as ...
more infohttp://patents.com/us-8143423.html
Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin - Pereira - 2012 -...  Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin - Pereira - 2012 -...
Suberoylanilide hydroxamic acid blocks self-renewal and homotypic aggregation of inflammatory breast cancer spheroids. Cancer ... Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, suppresses the growth of carcinogen-induced mammary ... Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin. ... Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK ...
more infohttp://onlinelibrary.wiley.com/doi/10.1002/ijc.27395/references
Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic...  Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic...
Abstract:Background: Anti-tumor effect of hydroxamic acid derivatives is largely connected with its properties as efficient ... Background: Anti-tumor effect of hydroxamic acid derivatives is largely connected with its properties as efficient inhibitors ... Results: Chemosensitizing properties of water soluble cyclic hydroxamic acids (CHA) are evaluated using in vitro activities and ... Results: Chemosensitizing properties of water soluble cyclic hydroxamic acids (CHA) are evaluated using in vitro activities and ...
more infohttp://www.eurekaselect.com/153577
Effects of paclitaxel (PTX) prodrug-based self-assembly peptide hydrogels combined with suberoylanilide hydroxamic acid (SAHA)...  Effects of paclitaxel (PTX) prodrug-based self-assembly peptide hydrogels combined with suberoylanilide hydroxamic acid (SAHA)...
... and suberoylanilide hydroxamic acid (SAHA) for cancer co-delivery (Nap-PTX-SAHA). The hydrogels exhibited uniform nanofibers ... In this work, we designed a self-assembly peptide hydrogel encapsulated paclitaxel (PTX) and suberoylanilide hydroxamic acid ( ... Effects of paclitaxel (PTX) prodrug-based self-assembly peptide hydrogels combined with suberoylanilide hydroxamic acid (SAHA) ... Effects of paclitaxel (PTX) prodrug-based self-assembly peptide hydrogels combined with suberoylanilide hydroxamic acid (SAHA) ...
more infohttp://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra19917h
CN103012207B - Diaryl propionyl-N-methyl hydroxamic acid type urease inhibitor and synthesis and application thereof 
        -...  CN103012207B - Diaryl propionyl-N-methyl hydroxamic acid type urease inhibitor and synthesis and application thereof -...
... methyl hydroxamic acid compounds having the general structural formula: they have good inhibition of urease, may be used to ... 3.权利要求1所述的二芳基丙酰-N-甲基氧肟酸系列化合物在制备抗胃炎、胃溃疡或抗尿路结石药物中的应用。 Diaryl propionyl claimed in claim 1 -N- methyl hydroxamic acid compound of ... Method propionic acid diaryl -N- methyl hydroxamic acid compound prepared as claimed in claim 1 species, characterized in that ... methyl hydroxamic acid compound
more infohttps://patents.google.com/patent/CN103012207B/en
IL131042D0 - Arylsulfonylamino hydroxamic acid derivatives 
      - Google Patents  IL131042D0 - Arylsulfonylamino hydroxamic acid derivatives - Google Patents
acid derivatives. hydroxamic acid. arylsulfonylamino hydroxamic. arylsulfonylamino. derivatives. Prior art date. 1997-02-03. ... IL131042D0 - Arylsulfonylamino hydroxamic acid derivatives - Google Patents. Arylsulfonylamino hydroxamic acid derivatives Info ... Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors US6340691B1 (en) 1999-01-27. 2002-01-22. American ... Arylsulfonamido-substituted hydroxamic acids US5863949A (en) 1995-03-08. 1999-01-26. Pfizer Inc. Arylsulfonylamino hydroxamic ...
more infohttps://patents.google.com/patent/IL131042D0/en