Paraneoplastic Encephalomyelitis Medication: Corticosteroids, Immunomodulators, Anticonvulsants
Paraneoplastic encephalomyelitis (PEM) is a multifocal inflammatory disorder of the central nervous system (CNS) associated ... Anti-Hu-associated paraneoplastic encephalomyelitis with esophageal small cell carcinoma. Intern Med. 2012. 51(17):2423-7. [ ... Neuronal surface antigen antibodies in limbic encephalitis: clinical-immunologic associations. Neurology. 2008 Sep 16. 71(12): ... encoded search term (Paraneoplastic%20Encephalomyelitis) and Paraneoplastic Encephalomyelitis What to Read Next on Medscape. ...https://emedicine.medscape.com/article/1157060-medication
Chapter 101. Paraneoplastic Neurologic Syndromes | Harrison's Principles of Internal Medicine, 18e | AccessMedicine | McGraw...
Anti-Hu. Encephalomyelitis, subacute sensory neuronopathy. SCLC. Anti-Yo. Cerebellar degeneration. Ovary, breast. ... Table 101-2 Antibodies to Intracellular Antigens, Syndromes, and Associated Cancers. View Table,Favorite Table,Download (.pdf) ... Table 101-1 Paraneoplastic Syndromes of the Nervous System. View Table,Favorite Table,Download (.pdf). Table 101-1 ... Paraneoplastic Neurologic Syndromes." Harrison's Principles of Internal Medicine, 18e Longo DL, Fauci AS, Kasper DL, Hauser SL ...http://accessmedicine.mhmedical.com/Content.aspx?bookId=331§ionId=40726837
Serial Positron Emission Tomography Findings and Neuropsychological Assessments in Limbic Encephalitis
Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients. Brain 2001;124(Pt 6):1138-48.. ... 반면 변연뇌염과 연관된 종양성신경세포 항원(onconeuronal antigen)은 대체로 세포 내에 존재하는 것으로 알려져 있고, 면역억제치료에 치료 반응이 적은 것으로 추정되고 있다. 또한 다양한 신생물딸림 자가항체 중에서 ... 일반적으로 신생물딸림 신경학적 증후군(paraneoplastic neurological syndrome)의 치료를 시행한 환자들의 수가 적고, 동반된 항암치료를 시행 받고 있는 경우가 많기 때문에 신생물딸림 신경학적 증후군의 ... Neurosyphilis and paraneoplastic limbic encephalitis: important differential diagnoses. J Neurol 2005;252: 1129-32.. ...http://jsms.sch.ac.kr/journal/view.php?doi=10.15746/sms.14.002
Association of Perioperative Beta-Blockade With Mortality and Cardiovascular Morbidity Following Major Noncardiac Surgery -...
Hu Paraneoplastic Encephalomyelitis Antigens, London, Heart Arrest, Vascular Surgical Procedures, Postoperative Period ...http://www.acc.org/latest-in-cardiology/journal-scans/2013/04/24/15/14/association-of-perioperative-beta-blockade-with-mortality-and-cv-morbidity
HuD (protein) - Wikipedia
Hu antigen D)". Szabo A, Dalmau J, Manley G, et al. (1991). "HuD, a paraneoplastic encephalomyelitis antigen, contains RNA- ... "Cell surface expression of paraneoplastic encephalomyelitis/sensory neuronopathy-associated Hu antigens in small-cell lung ... 1991). "HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal ... Dalmau J, Furneaux HM, Cordon-Cardo C, Posner JB (1992). "The expression of the Hu (paraneoplastic encephalomyelitis/sensory ...https://en.wikipedia.org/wiki/HuD_(protein)
Nerve tissue protein - Wikipedia
32 Fragile X Mental Retardation Protein GAP-43 Protein Glucose Transporter Type 3 Hu Paraneoplastic Encephalomyelitis Antigens ...https://en.wikipedia.org/wiki/Nerve_tissue_protein
Embryonic Lethal Abnormal Vision-Like RNA-Binding Proteins Regulate Neurite Outgrowth and Tau Expression in PC12 Cells |...
1992) The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuropathy) antigen in human normal and tumor tissues. ... 1991) HuD, a paraneoplastic encephalomyelitis antigen, contains RNA binding domains and is homologous to Elav and Sex-lethal. ... D, E, Confocal image of PC12 cells stained with anti-Hu serum. C, F, Control experiments showing no penetration of Cy3 or ... 1994) Tissue-specific expression of the gene encoding a mouse RNA binding protein homologous to human HuD antigen. DNA Res 1: ...http://www.jneurosci.org/content/19/16/6907?ijkey=1d6bf7f9c6a606582c2dc087d332877f1d2f34e2&keytype2=tf_ipsecsha
Frontiers | Anti-GAD65 Containing Cerebrospinal Fluid Does not Alter GABAergic Transmission | Frontiers in Cellular Neuroscience
2001). Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients. Brain 124, 1138-1148. doi: 10.1093/brain/ ... paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues. Am. J. Pathol. 141, 881-886. ... paraneoplastic antigen Ma2) in patients with testicular tumors (Voltz et al., 1999), to CRMP5/CV2 (collapsin response mediator ... 2007). Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann. Neurol. 61, 25-36 ...https://www.frontiersin.org/articles/10.3389/fncel.2016.00130/full
Frontiers | Detection and Characterization of Autoantibodies to Neuronal Cell-Surface Antigens in the Central Nervous System |...
In contrast to classical paraneoplastic disorders, AIE patients respond well to immunotherapy. The detection of neuronal ... In contrast to classical paraneoplastic disorders, AIE patients respond well to immunotherapy. The detection of neuronal ... we discuss the use of immunoprecipitation and mass spectrometry analysis for the detection of novel neuronal surface antigens, ... we discuss the use of immunoprecipitation and mass spectrometry analysis for the detection of novel neuronal surface antigens, ...https://www.frontiersin.org/articles/10.3389/fnmol.2016.00037/full
RNA-Binding Proteins | Harvard Catalyst Profiles | Harvard Catalyst
Hu Paraneoplastic Encephalomyelitis Antigens. *Iron Regulatory Protein 1. *Iron Regulatory Protein 2 ...https://connects.catalyst.harvard.edu/Profiles/display/Concept/RNA-Binding%20Proteins
anti-ELAVL2 antibody | Rabbit HuB Polyclonal Antibody-NP 001164666.1
Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD ... ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system ... ELAVL2; HUB; ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein ... Antigen. Biochemical. cDNA Clone. siRNA. Peptide. Rec./Purified Protein. Custom ELISA Kit. Custom Protein. Custom Antibody. ... The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then ...https://www.mybiosource.com/prods/Antibody/Polyclonal/HuB/ELAVL2/datasheet.php?products_id=8211333
Immune-Mediated Paraneoplasia - Redorbit
POP66, a paraneoplastic encephalomyelitis-related antigen, is a marker for adult oligodenrocytes. J Neuropathol Exp Neurol 1998 ... Major histocompatibility proteins, anti-Hu antibodies and paraneoplastic encephalomyelitis in neuroblastoma and small cell lung ... Immunization with the paraneoplastic encephalomyelitis antigen HuD does not cause neurologic disease in mice.Neurology 1995; 45 ... Immunization with the paraneoplastic encephalomyelitis antigen HuD does not cause neurologic disease in mice. Neurology 1995; ...http://www.redorbit.com/news/health/795657/immunemediated_paraneoplasia/
mRNA Cleavage and Polyadenylation Factors | Profiles RNS
Hu Paraneoplastic Encephalomyelitis Antigens. *Iron Regulatory Protein 1. *Iron Regulatory Protein 2 ...https://profiles.umassmed.edu/display/122850
Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma | Journal of Hematology & Oncology |...
... high titers of circulating anti-HuD antibodies in patients and spontaneous tumor remission suggests that the HuD-antigen might ... The HuD-antigen is a neuronal RNA-binding protein that is expressed in 100% of SCLC tumor cells and over 50% of neuroblastoma ... Cell surface expression of paraneoplastic encephalomyelitis/sensory neuronopathy-associated Hu antigens in small-cell lung ... Dalmau J, Furneaux HM, Cordon-Cardo C, Posner JB: The expression of the Hu (paraneoplastic encephalomyelitis/sensory ...https://jhoonline.biomedcentral.com/articles/10.1186/s13045-014-0091-3
PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGEN HUD HOMOLOG (HU-ANT HUD_MOUSE PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGEN HUD HOMOLOG (HU ... PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGEN HUD (HU-ANTIGEN D) O55010 HU-ANTIGEN D (RNA BINDING PROTEIN ELAVL4) - MUS MUSCULUS (MO ... HU-ANTIGEN C - MUS MUSCULUS (MOUSE). HUC_HUMAN HU-ANTIGEN C (PARANEOPLASTIC CEREBELLAR DEGENERATION-ASSOCIA P79736 ELAV/HUC ... WORKLIST ENTRIES (1): HUDSXLRNA View alignment Paraneoplastic encephalomyelitis antigen family signature Type of fingerprint: ...http://126.96.36.199/cgi-bin/dbbrowser/PRINTS/DoPRINTS.pl?cmd_a=Display&qua_a=/Full&fun_a=Code&qst_a=HUDSXLRNA
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE‐containing mRNAs | The...
... have been previously identified as target antigens in paraneoplastic encephalomyelitis sensory neuronopathy (the Hu syndrome), ... Dalmau J, Graus F, Rosenblum MK and Posner JB (1991) Anti‐Hu associated paraneoplastic encephalomyelitis/sensory neuropathy, a ... Posner JB (1995) Anti‐Hu autoantibody‐associated sensory neuropathy/encephalomyelitis, a model of paraneoplastic syndrome. ... a paraneoplastic encephalomyelitis antigen, contains RNA‐binding domains and is homologous to elav and sex‐lethal. Cell, 67, ...http://emboj.embopress.org/content/17/12/3448
Anti-HuD antibody [16C12AA10] (ab171448) | Abcam
Hu antigen D antibody. *Hu-antigen D antibody. *HuD antibody. *Paraneoplastic encephalomyelitis antigen HuD antibody ...https://www.abcam.com/hud-antibody-16c12aa10-ab171448.html
Elavl4 MGI Mouse Gene Detail - MGI:107427 - ELAV like RNA binding protein 4
IPR002343 Paraneoplastic encephalomyelitis antigen. IPR035979 RNA-binding domain superfamily. IPR000504 RNA recognition motif ... IPR006548 Splicing factor ELAV/Hu. IPR034775 Splicing factor ELAV/Hu, RNA recognition motif 1 ... Tissue-specific expression of the gene encoding a mouse RNA binding protein homologous to human HuD antigen. DNA Res. 1994;1(4 ...http://www.informatics.jax.org/marker/MGI:107427
Welcome to LibAge, the ageing reference resource
Hu Paraneoplastic Encephalomyelitis Antigens/metabolism *Humans *Larva/ultrastructure *Male *Membrane Proteins *Mice ...http://libage.ageing-map.org/entries/tags/1358/
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Immunohistochemical analy- sis of anti-Hu-associated paraneoplastic encephalomyelitis. Antibodies to glutamate receptors A ... You should prefer brighter fluorochrome for the benefit of dimly expressed antigen or exchange for antigens expressed simply on ... pylori antigen in stool, such as the enzyme immunoassay check (EIA) based on polyclonal or monoclonal antibodies and ... bunch of hypothetical studies secure shown modulation of the objective antigen at near antibodies to NMDA receptors. ...http://teenaids.org/wp-content/mission/part47/info2/
N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly...
Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients. Brain. 2001;124:1138-48. [PubMed] ... intrathecal antigen spreading with production of different antibody specificities occurs; such non-NMDAR antigen immunization ... 5A. Overall, there was no difference in the outcomes between the paraneoplastic, non-paraneoplastic and childhood cases. ... 2D. The fluorescent immunoprecipitation assay values were higher in the paraneoplastic than in the non-paraneoplastic patients ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2877907/
Biomolecules | Free Full-Text | Guardian of Genetic Messenger-RNA-Binding Proteins | HTML
... a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to elav and sex-lethal. Cell 1991, ... The Hu family members (HuR, HuB, HuC, and HuD) are a second set of RBPs with diverse functions and mediate antigen-associated ... Buckanovich, R.J.; Posner, J.B.; Darnell, R.B. Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and ... The Hu family of RBPs is another example involved in the development of cancer. Of the Hu family of proteins, HuR is the one ...http://www.mdpi.com/2218-273X/6/1/4/htm
Paraneoplastic neurologic syndromes affect all parts of the nervous system. An immune response to tumor antigens that cross- ... and can occur as part of a more diffuse anti-Hu syndrome (the encephalomyelitis and subacute sensory neuropathy syndrome). ... This leads to manifestations that vary depending on where in the nervous system these antigens are expressed. Paraneoplastic ... and remote paraneoplastic effects from tumor products or immune cross-reaction with tumor antigens (Box 2). ...http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/lung-cancer/
Autoantibody Markers - AACC.org
... paraneoplastic syndromes (PNS), and ataxia. While these three conditions represent only a part of the spectrum of neurological ... Patients with paraneoplastic cerebellar degeneration, paraneoplastic encephalomyelitis, multiple sclerosis, celiac disease, and ... Intracellular Antigens A second class of autoantibodies involved in encephalitis, PNS, and ataxia target intracellular antigens ... A higher proportion of women have this autoantibody compared to men (2:1), and a patient also can have antibodies to Hu (25%), ...https://www.aacc.org/publications/cln/articles/2012/march/autoantibody-markers.aspx
Gentaur Molecular :EIAab \ ELISA kit 35-beta calcimedin,Annexin A4,Annexin IV,Annexin-4,ANX4,ANXA4,Chromobindin-4,Endonexin I...
ELAVL4 HUD PNEM] ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD). [REXO1L1P GOR REXO1L1 ... Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21) ... apa modD Rv1860 MTCY359.13] Alanine and proline-rich secreted protein Apa (45 kDa glycoprotein) (45/47 kDa antigen) (Antigen ... S7] Core protein VP7 (Capsid protein VP7) (VP7 antigen).  Toxin TbTx5 (T-alpha* NaTx3.4). [NA] Neuraminidase (EC 188.8.131.52) ( ...http://www.antibody-antibodies.com/product2767227-search-ELISA_kit__35_beta_calcimedin,Annexin_A4,Annexin_IV,Annexin_4,ANX4,ANXA4,Chromobindin_4,Endonexin_I,Lipocortin_IV,P32.5,PAP_II,Pig,Placental_anticoagulant_protein_II,PP4_X,Protein_II,Sus_scrofa.html