In order to investigate the similarity and diversity of the enzymatic properties of Hjc as a Holliday junction resolvase, ... Biochemical characterization of the Hjc Holliday junction resolvase of Pyrococcus furiosus. In: Nucleic acids research. 2000 ; ... In order to investigate the similarity and diversity of the enzymatic properties of Hjc as a Holliday junction resolvase, ... In order to investigate the similarity and diversity of the enzymatic properties of Hjc as a Holliday junction resolvase, ...

Ip SC, Rass U, Blanco MG, Flynn HR, Skehel JM, West SC (2008). "Identification of Holliday junction resolvases from humans and ... Lorenz A, West SC, Whitby MC (2010). "The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a ... The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that ... GEN1, Holliday junction 5 flap endonuclease is a protein that in humans is encoded by the GEN1 gene. This gene encodes a ...

part_of Holliday junction resolvase complex IBA Inferred from Biological aspect of Ancestor. more info ... Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex. Amangyeld T, et ... Title: Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex. ... contributes_to crossover junction DNA endonuclease activity IBA Inferred from Biological aspect of Ancestor. more info ...

The Dissolution of Double Holliday Junctions. Anna H. Bizard and Ian D. Hickson. Holliday Junction Resolvases. Haley D.M. Wyatt ...

Macmaster, R.; Sedelnikova, S.; Baker, P.J.; Bolt, E.L.; Lloyd, R.G.; Rafferty, J.B. RusA Holliday junction resolvase: DNA ...

Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus ... Activity screening demonstrated that purified recombinant Hjc_15-6 acts as a resolvase, cleaving Holliday-junction oligomers. ... Holliday junction-resolving enzymes are nucleases that cleave four-way DNA-Holliday junctions (Hjs) into two unconnected DNA ... Holliday-junction resolving enzyme Hjc. O28314 (HJC_ARCFU). 139. 2.8-3.1. Archaeoglobus fulgidus ...

1998) Substrate specificity of the SpCCE1 Holliday junction resolvase of Schizosaccharomyces pombe Journal of Biological ... 2003) Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis Molecular Cell 12:761- ... 2007) Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? The EMBO Journal 26: ... Synthetic IFSA junction. Request a detailed protocol The IFSA junction was made by annealing oligonucleotides oMW305, oMW306, ...

Family c.55.3.8: Putative Holliday junction resolvase RuvX [102485] (3 proteins). automatically mapped to Pfam PF03652. ...

Family c.55.3.8: Putative Holliday junction resolvase RuvX [102485] (3 proteins). automatically mapped to Pfam PF03652. ...

... archaeal Holliday junction resolvases, MutH methyl-directed DNA mismatch-repair endonucleases, and catalytic domains of many ... archaeal Holliday junction resolvases, MutH methyl-directed DNA mismatch-repair endonucleases, and catalytic domains of many ...

... was purified from HeLa cells as part of a small protein complex possessing a Holliday junction (HJ) resolvase activity (Liu et ... Based on the marked reduction in Holliday junction (HJ) resolution activity in Rad51c-null mouse embryonic fibroblasts, we ... Holliday junction; MEF, mouse embryonic fibroblast; neo, neomycin; PGK, phosphoglycerate kinase; PMS, pregnant mare serum; PSSC ... Holliday junction; MEF, mouse embryonic fibroblast; neo, neomycin; PGK, phosphoglycerate kinase; PMS, pregnant mare serum; PSSC ...

Finally, the MutLγ-MutSγ-EXO1-RFC-PCNA nuclease ensemble preferentially cleaves DNA with Holliday junctions, but shows no ... but shows no canonical resolvase activity. Instead, it probably processes meiotic recombination intermediates by nicking double ... This mode of MutLγ nuclease activation might explain crossover-specific processing of Holliday junctions or their precursors in ... This mode of MutLγ nuclease activation might explain crossover-specific processing of Holliday junctions or their precursors in ...

S. H. Lee, L. N. Princz, M. F. Klugel, B. Habermann, B. Pfander & C. Biertumpfel: Human Holliday junction resolvase GEN1 uses a ... The so-called Holliday structure has nothing to do with holidays or vacation, but is rather a term that describes a complex ... Researcher Robin Holliday proposed this structure of genetic information in the 1960s. It occurs in DNA repair processes in our ... The Holliday structure that emerges is then resolved again by GEN1 at the end of the repair process. ...

Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage. L.SH Et Al. P.LN ... In homoscleromorph sponges, we can find all features of a true epithelial structure, including adherens junctions, a basement ...

The talk will explain structural insights into human Holliday junction resolvase GEN1 and our efforts to reconstitute a minimal ...

Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis). cog/ ... Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis). cog/ ...

Holliday junction resolvase RecU. O31666 MTNW. 405. 788. 22.5. 0.08. 2,3-diketo-5-methylthiopentyl-1-phosphate enolase. ...

Phage Holliday junction resolvase. locus,SAG0569, protein_id,NP_687598.1, gi,22536747, geneID,1013373. ...

CBSS-281090.3.peg.464 Putative Holliday junction resolvase YqgF. *PFAM: YqgF (CL0580) RuvX; Holliday junction resolvase ( ...

Holliday junction resolvase complex GO:0048476 * cytoplasmic transcriptional repressor complex GO:0090569 ...

Holliday junction resolvase-like protein YP_001043224 decreased coverage 0.00888056 normal 0.184568 Rhodobacter sphaeroides ...

The OsGEN-L protein from Oryza sativa possesses Holliday junction resolvase activity as well as 5′-flap endonuclease activity. ...

"Holliday junction resolvase [Ensembl].","protein_coding" "AGT23679","N559_1946","Klebsiella pneumoniae","septum formation ...

We describe the identification and initial biochemical characterisation of a new Holliday junction resolvase from ... Interactions Between RuvA and RuvC at Holliday Junctions: Inhibition of Junction Cleavage and Formation of a RuvA-RuvC-DNA ... Generating Crossovers by Resolution of Nicked Holliday Junctions - A Role for Mus81-Eme1 in Meiosis Fekret Osman, Julie Dixon, ... Resolvase activity was initially detected in partially purified cell-free extracts of S. pombe. Resolution of X-junction DNA ...

Aravind L, Makarova KS, Koonin EV: Holliday junction resolvases and related nucleases: identification of new families, phyletic ...

Holliday Junction Resolvases. *Micrococcal Nuclease. *Mismatch Repair Endonuclease PMS2. *MRE11 Homologue Protein ...

Genes encoding proteins including RecA, RecF, RecO, RecR, RecG and Holliday junction resolvases RuvA, RuvB and RuvC are ...

... and rqh1 mutants is suppressed by a Holliday junction resolvase (RusA), as is the synthetic lethality of a mus81(-) rqh1(-) ... readily cleaves replication fork structures but cleaves synthetic Holliday junctions relatively poorly in vitro. From these ... data we propose that Mus81-Eme1 can process stalled replication forks before they have regressed to form a Holliday junction. ... In fission yeast DNA junctions at stalled replication forks appear to be processed by either the Rqh1 DNA helicase or Mus81- ...