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*  Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications | PNAS
Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications. J Moriuchi, ... A cDNA clone, pDSH-9.1, encoding the alpha chain of a DQ molecule derived from an HLA-DRw9 homozygous cell line has been ... Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications ... Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications ...
http://www.pnas.org/content/82/10/3420
*  HLA-DQB1 | Cancer Genetics Web
Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding ... The genotype of HLA-A, HLA-B, HLA-DR, and HLA-DQ alleles was typed by means of PCR sequence-specific priming.. RESULTS: HLA-B* ... HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) ... HLA-B*07 (21·3% and 11·1%), HLA-C*07 (46·7 and 28·2%), HLA-DQB1*03 (62·7% and 37·3%), HLA-DRB1*11 (30·0% and 16·0%) and HLA- ...
http://www.cancerindex.org/geneweb/HLA-DQB1.htm
*  Sequence Similarity - 1FYT: CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA...
DR ALPHA CHAIN ALPHA CHAIN, RESIDUES 26-207 9606 165 4GG6 1 A, C HLA class II histocompatibility antigen, DQ alpha 1 chain ... HLA class II histocompatibility antigen, DR alpha chain 9606 31 5KSV 1 A MHC class II HLA-DQ-alpha chain UNP residues 1-193 ... MHC class II HLA-DQ-alpha chain 9606 45 4OV5 1 A, D, G, J, M, P HLA class II histocompatibility antigen, DR alpha chain ... HLA class II histocompatibility antigen, DR alpha chain 9606 144 4Z7W 1 A, C MHC class II HLA-DQ-alpha chain UNP residues 1-184 ...
http://www.rcsb.org/pdb/explore/sequenceCluster.do?structureId=1FYT&entity=1&seqid=50
*  HLA DQ Antibody (TAL 4.1) [Janelia Fluor® 646] (NB100-2700JF646): Novus Biologicals
Mouse Monoclonal Anti-HLA DQ Antibody (TAL 4.1) [Janelia Fluor® 646]. Validated: Flow, IHC. Tested Reactivity: Human. 100% ... leukocyte antigen alpha chain. *major histocompatibility complex, class II, DQ alpha 1 ... Home » HLA DQ » HLA DQ Antibodies » HLA DQ Antibody (TAL 4.1) [Janelia Fluor® 646] ... Reviews for HLA DQ Antibody (NB100-2700JF646) (0) There are no reviews for HLA DQ Antibody (NB100-2700JF646). By submitting a ...
https://www.novusbio.com/products/hla-dq-antibody-tal-41_nb100-2700jf646
*  Detecting Celaic Disease in Your Patients - American Family Physician
Approximately 95 percent of patients with celiac disease have a particular type of HLA DQ alpha and beta chain encoded by two ... Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med. 1989;169:345-50. ... HLA-DQA1 0501 and HLA-DQB1 0201.10 If people genetically predisposed to celiac disease do not ingest gluten, they have no ... Studies of patients with celiac disease using molecular techniques demonstrate a strong association with specific HLA class II ...
https://www.aafp.org/afp/1998/0301/p1023.html
*  HLA DQ Antibody (TAL 4.1) [DyLight 488] (NB100-2700G): Novus Biologicals
Mouse Monoclonal Anti-HLA DQ Antibody (TAL 4.1) [DyLight 488]. Validated: WB, ELISA, Flow, IHC, IHC-Fr. Tested Reactivity: ... Alternate Names for HLA DQ Antibody (TAL 4.1) [DyLight 488]. *CD. *CELIAC1DQ alpha 1 chain ... Home » HLA DQ » HLA DQ Antibodies » HLA DQ Antibody (TAL 4.1) [DyLight 488] ... Reviews for HLA DQ Antibody (NB100-2700G) (0) There are no reviews for HLA DQ Antibody (NB100-2700G). By submitting a review ...
https://www.novusbio.com/products/hla-dq-antibody-tal-41_nb100-2700g
*  MHC Evolution [M.Tevfik Dorak]
Moriuchi J, Moriuchi T, Silver J: Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and ... the class II MHC alpha chain and beta 2-microglobulin and between the class II MHC beta-chain and the class I alpha chain 1. ... Gyllensten UB, Erlich HA: Ancient roots for polymorphism at the HLA-DQ alpha locus in primates. Proceedings of the National ... Karr RW, Gregersen PK, Obata F, Goldberg D, Maccari J, Alber C, Silver J: Analysis of DR beta and DQ beta chain cDNA clones ...
http://dorakmt.tripod.com/mhc/mhcevol.html
*  An immunogenetic heterogeneity in multiple sclerosis. | Journal of Neurology, Neurosurgery & Psychiatry
... no association of MS with glutamine at position 34 of the HLA-DQ alpha chain or with defined sequences of the HLA-DQB1 gene was ... The results of genomic HLA class II typing with restriction fragment length polymorphism analysis of 62 MS patients from ...
http://jnnp.bmj.com/content/55/10/887
*  HLA-DQ - Wikipedia
In the human population DQ is highly variable, the β subunit more so than the alpha chain. The variants are encoded by the HLA ... The DQ loci are in close genetic linkage to HLA-DR, and less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. ... Both α-chain and β-chain vary greatly. A person often produces two α-chain and two β-chain variants and thus 4 isoforms of DQ. ... HLA DQ- subunit alleles, mature chains, contact variants Known. HLA-DQ. Potential ...
https://en.m.wikipedia.org/wiki/HLA-DQ
*  HLA-DQ6 - Wikipedia
"Subtle differences in HLA DQ haplotype-associated presentation of AChR alpha-chain peptides may suffice to mediate myasthenia ... DQ) serotype group. The serotype is determined by the antibody recognition of β6 subset of DQ β-chains. The β-chain of DQ ... HLA-DQ6 and DQB1*06 are almost synonymous in meaning. DQ6 β-chains combine with α-chains, encoded by genetically linked HLA- ... HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ ( ...
https://en.wikipedia.org/wiki/HLA-DQ6
*  HLA-DQ - Wikipedia
... the β subunit more so than the alpha chain. The variants are encoded by the HLA DQ genes and are the result of single ... The DQ loci are in close genetic linkage to HLA-DR, and less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. Different ... Both α-chain and β-chain vary greatly. A person often produces two α-chain and two β-chain variants and thus 4 isoforms of DQ. ... Serological studies of DQ recognized that antibodies to DQ bind primarily to the β-chain. The currently used serotypes are HLA- ...
https://en.wikipedia.org/wiki/HLA-DQ
*  PDB 1uvq
HLA class II histocompatibility antigen, DQ alpha 1 chain. P01920. DQB1_HUMAN. Homo sapiens. HLA class II histocompatibility ... Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy ...
http://www.cathdb.info/pdb/1uvq
*  Reactome | HLA class II histocompatibility antigen, DQ [integral component of lumenal side of endoplasmic reticulum membrane]
Formation of MHC II alpha beta heterodimer (Homo sapiens) * HLA II beta chain [integral component of lumenal side of ... HLA class II histocompatibility antigen, DQ [Golgi membrane] HLA class II histocompatibility antigen, DQB1*0602 beta chain ... HLA class II histocompatibility antigen, DQ [plasma membrane] HLA class II histocompatibility antigen, DQB1*0602 beta chain ... HLA class II histocompatibility antigen, DQ [lysosomal membrane] HLA class II histocompatibility antigen, DQB1*0602 beta chain ...
http://www.reactome.org/content/detail/2130611
*  Association of Neovascular Age-Related Macular Degeneration with Specific Gene Expression Patterns in Peripheral White Blood...
HLA-DQA2 HLA class II histocompatibility antigen, DQ(6) alpha chain precursor. NM_020056.2 Hs.591798. 1.6. ... HLA-DQA2 HLA class II histocompatibility antigen, DQ(6) alpha chain precursor. NM_020056.2 Hs.591798. 1.6. ... Genes included in this group were HLA-DQA1, HLA-DQA2, and HLA-DQB1. These genes showed increased mRNA levels in patients with ... Specific alleles of such HLA genes have been associated with the risk for AMD. 44 Abnormal antigen presentation of retinal or ...
https://iovs.arvojournals.org/article.aspx?articleid=2186361
*  A genome-wide association study of myasthenia gravis. - PubMed - NCBI
HLA-DQ alpha-Chains. *HLA-DQA1 antigen. Grant support. *ZIA AG000933-02/NULL/Intramural NIH HHS/United States ... HLA-DQA1 (rs9271871; P=1.08×10(-8); odds ratio, 2.31; 95% CI, 2.02-2.60), and TNFRSF11A (rs4263037; P=1.60×10(-9); odds ratio, ... HLA-DQA1; rs601006; P=2.52×10(-11); odds ratio, 4.0; 95% CI, 3.57-4.43), although the set of single-nucleotide polymorphisms ... HLA-DQA1; rs9271871; P=7.02×10(-18); odds ratio, 4.27; 95% CI, 3.92-4.62). Association within the major histocompatibility ...
https://www.ncbi.nlm.nih.gov/pubmed/?term=25643325
*  AllergyCases.org: Mnemonics: T Lymphocytes
1 letter HLA: ABC. 1 polypeptide chain MHC (alpha and beta-2 microgobulin). II. 2 letters HLA: DP, DQ, DR. 2 polypeptide chains ... ZAP 70 binds to the Zeta chain (CD247) of the T-cell receptor.. Z. ZAP-70. Zeta-chain-associated protein kinase 70 (70 is the ... T-cell receptor complex with TCR-α and TCR-β chains. Image source: Wikipedia.. This video describes the process by which ... MHC II - genes D, again alphabetical - DP, DQ, DR. Both on chromosome 6. I......II. ABCD PQR. MHC. I. ...
http://www.allergycases.org/2007/01/mnemonics-t-lymphocytes.html
*  Renal Fellow Network: May 2018
... one alpha chain and a beta2-microglobulin; epitopes located on the polymorphic alpha chain.. HLA Class II: DR, DQ, DP; present ... De-novo DSA mainly develop against HLA Class II antigens (often DQ). The risk factors for de-novo DSA formation include: ... DSA target specific epitopes in the polymorphic regions of the HLA antigens (see NephMadness for more on epitopes/eplets).. HLA ... on all antigen-presenting cells, one alpha & 1 beta chain; both chains are polymorphic. ...
http://renalfellow.blogspot.com/2018/05/
*  Reactome | HLA class II histocompatibility antigen, DQ [plasma membrane]
HLA II alpha chain [plasma membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ [plasma ... HLA II alpha chain [plasma membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ [plasma ... HLA II alpha chain [plasma membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ [plasma ... HLA II alpha chain [plasma membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ [plasma ...
https://reactome.org/content/detail/R-RNO-197585
*  HLA-DRB1 monoclonal antibody, clone LN-3 - (MAB13306) - Products - Abnova
Mouse monoclonal antibody raised against native human HLA-DRB1. Activated human peripheral blood mononuclear cells. (MAB13306 ... HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) ... This monoclonal antibody does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein ... HLA class II antigen beta chain,HLA class II histocompatibility antigen, DR-1 beta chain,HLA-DR-beta 1,MHC class II HLA-DR beta ...
http://www.abnova.com/products/products_detail.asp?catalog_id=MAB13306
*  Reactome | HLA class II histocompatibility antigen, DQ [transport vesicle membrane]
HLA II alpha chain [transport vesicle membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ ... HLA II alpha chain [transport vesicle membrane] (Rattus norvegicus) * Homologues of HLA class II histocompatibility antigen, DQ ... HLA class II histocompatibility antigen, DQ [Golgi membrane] HLA class II histocompatibility antigen, DQ [trans-Golgi network ... HLA class II histocompatibility antigen, DQ [trans-Golgi network membrane] HLA class II histocompatibility antigen, DQ [ ...
https://reactome.org/content/detail/R-RNO-2130581-2
*  MHC-II Monoclonal Mouse Antibody (169-1B5.2) | Biotium
It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha ... heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic ... In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells ... HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. ...
https://biotium.com/product/monoclonal-anti-mhc-ii-hla-dra-169-1b5-2/
*  Genetic and Immunologic Biomarkers in Type 1 Diabetes
... beta chains may have as m any as 23 and 120 alleles circulating in a population respectively Genes encoding the HLA DQ alpha ... respectively HLA DR has but one locus for the alpha chain, which is largely invariable, but nine loci for the beta chain, ... an alpha chain (referenced as IL2r or CD25), a beta chain (referenced as IL2r or CD122) and a common gamma chain (IL2r or CD127 ... HLA DQ, and HLA DR. Genes encoding the HLA DP apha and ... The alpha chain in combination with the beta and gamma chains ...
http://ufdc.ufl.edu/UFE0045760/00001
*  RCSB PDB - Protein Feature View - HLA class II histocompatibility antigen, DQ beta 1 chain - P01920 (DQB1 HUMAN)
... class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta ... HLA class II histocompatibility antigen, DQ beta 1 chain - P01920 (DQB1_HUMAN) ... also known as invariant chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 ... MHC class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of ...
http://www.rcsb.org/pdb/protein/P01920