施信如教授 Dr. Shin-Ru Shih - Research Center for Emerging Viral Infections, Chang Gung University
Lam TT, Chong YL, Shi M, Hon CC, Li J, Martin DP, Tang JW, Mok CK, Shih SR, Yip CW, Jiang J, Hui RK, Pybus OG, Holmes EC, Leung ... Expression of capsid protein VP1 for use as antigen for the diagnosis of enterovirus 71 infection. J. Med. Virol., 61:228-234, ... HLA-33 is associated with susceptibility to enterovirus 71 infection. Pediatrics, 122: 1271-1276, 2008. ... Shih SR, Chen GW, Yang CC, Yang WZ, Tsao KC, Huang CG, Huang YL, Lin TY, Liu DP, Chiu SC, Lin JH, Chen HY, Wang JR, Kao CL, Lin ...
Trends in the outpatient-visits and allergens of allergic rhinitis in Chongqing, China from 2008 to 2017 | Research Square
Relationship between soluble HLA-G and HLA-A,-B,-C serum levels, and interferon-gamma production after sublingual immunotherapy ... Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK et al. Worldwide time trends in the prevalence of symptoms ... It provides information about the presence of specific IgE to protein and peptide antigens (allergens). Aeroallergen ...
Epstein-Barr virus-encoded microRNAs as regulators in host immune responses
... thereby dampening the antigen presentation pathway [74]. EBV miRNAs also limit cell surface levels of HLA class II molecules, ... Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115:787-98 ... providing an alternative way to block MHC class II antigen presentation. Lymphocyte antigen 75 (LY75) delivers antigens from ... 1) EBV miRNAs can efficiently interfere with MHC class I-mediated antigen presentation by targeting the antigen transporter ...
The effects of statins on the function and differentiation of blood cells
While simvastatin can prevent extra levels in antigen cross-presentation through APC, poor absorption of soluble antigen seems ... HLA-DR and CD38 expression. ↑ Superantigen-mediated T cell activation. Atorvastatin. In vitro: 10 mM. Human endothelial cell ... Sahebkar A, Serban C, Mikhailidis DP, . Association between statin use and plasma d-dimer levels: a systematic review and meta- ... statins disrupt processing and presentation of antigens by MHC class II in human DCs and B lymphocytes via reduced antigen ...
Changing Paradigms of Treating Severe Keratitis in Dry Eye Disease - touchOPHTHALMOLOGY
The major histocompatibility complex class II cell surface receptor, human leucocyte antigen-D related (HLA-DR) is a good ... Sendrowski DP, Jaanus SD, Semes LP, Stern ME, Chapter 12: Anti-inflammatory Drugs. In: Bartlett JD, Jaanus SD, Clinical Ocular ... Measurement of the expression levels of the inflammatory biomarker, human leukocyte antigen (HLA-DR), was a planned exploratory ... A reduction in the ocular surface inflammation (HLA-DR expression) was observed at Month 6 in favour of CsA treatment over ...
Tumor Mutational Burden as a Predictor of Immunotherapy Response: Is More Always Better? | Clinical Cancer Research | American...
Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in ... HLA locus heterozygosity, which dictates neoantigen diversity, and mutational clonality have a significant impact on antitumor ... Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy ... genetic mutations that impair antigen processing and presentation by tumors also represent a formidable barrier to effective ...
Medicine - University of Galway
Dendritic cell turnover, antigen uptake, and trafficking in the kidney and its draining lymph tissue. 2003. Poster presentation ... Comparative gene expression analysis of histologically normal HLA-identical and non-identical living donor kidney transplants. ... Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic ... 2003) Dendritic cell turnover, antigen uptake, and trafficking in the kidney and its draining lymph tissue. 2003. Poster ...
Microglial pathology | Acta Neuropathologica Communications | Full Text
HLA-DR antigens are present on large numbers of non-activated, ramified microglia in normal human brain [74],[75] and HLA-DR ... Good PF, Werner P, Hsu A, Olanow CW, Perl DP: Evidence of neuronal oxidative damage in Alzheimers disease. Am J Pathol 1996, ... Staining for HLA-DR antigens is of particular interest since many antibodies directed against these antigens are available and ... C-E, anti-HLA-DR antigen immunohistochemistry (LN-3 antibody) shows dystrophic spheroid formation (C), atrophic deramified ...
Ex vivo generation of platelet products from human iPS cells | Inflammation and Regeneration | Full Text
Moreover, alloantibodies against human leukocyte antigen class I (HLA-I) and to a lesser extent to human platelet antigen (HPA ... Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, et al. Senescence-associated secretory phenotypes reveal cell- ... These patients with allo-PTR require HLA-I/HPA-matched platelet transfusions, presumed to be more than 20,000 bags of platelets ... In addition, a system that stably supplies HLA-compatible platelets can be constructed by using the patients themselves or ...
Gene duplication and fragmentation in the zebra finch major histocompatibility complex | BMC Biology | Full Text
3-Dimensional structure of the human class-II histocompatibility antigen HLA-DR1. Nature. 1993, 364: 33-39. 10.1038/364033a0. ... Brown JW, Rest JS, Garcia-Moreno J, Sorenson MD, Mindell DP: Strong mitochondrial DNA support for a Cretaceous origin of modern ... Comparison of gene density across three avian lineages and the human HLA region. Estimates from zebra finch are based on two ... The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature. 1987, 329: 593- ...
2018 Publications - Hudson Institute of Medical Research
Design of peptide-based nanovaccines targeting leading antigens from gynecological cancers to induce HLA-A2.1 restricted CD8 ... Richardson AM, Lewis DP, Kita B, Ludlow H, Groome NP, Hedger MP, de Kretser DM, Lidbury BA (2018) Weighting of orthostatic ... Yuen HLA, Low MSY, Fedele P, Kalff A, Walker P, Bergin K, Coutsouvelis J, Grigoriadis G, Spencer A (2018) DCEP as a bridge to ... Leong TL, Gayevskiy V, Steinfort DP, De Massy MR, Gonzalez-Rajal A, Marini KD, Stone E, Chin V, Havryk A, Plit M, Irving LB, ...
DLS CodeMap® - NCD / LCD
HLA-A,B,C,DR,DQA,DQB,DP Deceased 81370. 81376. A57970 A57970 ... Hepatitis B Surface Antigen. 87340 NCD 210.6 499 Hepatitis B ... HLA-B27. 86812 NCD 190.1 468P HCG, Quant Pregnancy. 84702 NCD 190.27 Yes 84702 - Not more than once per month for diagnostic ... HLA-A,B,C,DR,DQ, Renal. 81370 A57970 7137 ... HLA-A,B,C,DR,DQ Typing (TRALI) 81370 A57970 7148 HLA-C 81373 ... HLA A,B Typing (Platelet Refractory). 86813 NCD 190.1 7140 ... HLA-DQB 81376 A57970 7162 Chlamydia / GC TMA, Throat. 87491 NCD ...
Molecular basis of human cerebral malaria development | Tropical Medicine and Health | Full Text
The critical role of CD8α+ DCs as the major antigen-presenting subset in CM was further demonstrated in the protection against ... Dp B. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281-97. ... immunogenetic variants such as HLA alleles; and (6) immunological components such as complement receptor 1, NOS2, TNF-α, and ... In addition, the cytoadherence of pRBCs to brain endothelial cells could lead to malaria antigen uptake via a trogocytosis-like ...
pbmc - Page 3 - Sanguine Bio Researcher Blog
Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells. Fischer ... CD4+ CD8+ double positive (DP) T cells in health and disease. Parel Y, Chizzolini C. Autoimmun Rev. 2004 Mar;3(3):215-20. ... and the MHC class II cell surface receptor HLA-DR, are co-expressed with FoxP3 in the CD45RA-FoxP3high TREG population and may ... Both CD4 and CD8 T cells can be further subsetted into naïve, and the antigen-experienced central memory, effector memory, and ...
Items where Year is 2006 - D-Scholarship@Pitt
Curran, DP and Zhang, Q and Richard, C and Lu, H and Gudipati, V and Wilcox, CS (2006) Total synthesis of a 28-member ... Vujanovic, Lazar Nikola (2006) Promoting Type-1 CD4+ T Cell Immune Responses Against Tumor-Associated Antigen MAGE-A6. Doctoral ... Ge, Xinhui (2006) Experimental Evidence For the Peptide Competition Between Type 1 Diabetes Associated HLA-DQ8 and DR4 ... Hamel, E and Day, BW and Miller, JH and Jung, MK and Northcote, PT and Ghosh, AK and Curran, DP and Cushman, M and Nicolaou, KC ...
Chiroindex.org - Index To Chiropractic Literature
HLA-B27 TESTING IN ANKYLOSING SPONDYLITIS: AN ANALYSIS OF THE PRETESTING ASSUMPTIONS [ANALYSIS BY WILLIAM R. DOLD] *Baron M ... by digital rectal examination and serum prostate-specific antigen [case report] *Johnson TL Jr ... Gilkey DP. *Peel JL. *Kennedy CA. J Manipulative Physiol Ther: Feb 2010(33:2): 88-95 20973. Risk factors associated with back ...
Diagnosis of Liver Involvement in Primary Sjögren Syndrome
HLA class II antigens and adhesion molecules.61,66,67. Outcome and management of PBC-associated SS. Few studies have evaluated ... Bogdanos DP, Smith H, Ma Y, Baum H, Mieli-Vergani G, Vergani D. A study of molecular mimicry and immunological cross-reactivity ... soluble liver antigen/liver-pancreas antigen; SS, Sjögren syndrome; SLE, systemic lupus erythematosus; SMA, smooth muscle ... Smyth et al28 have reported that HCV patients carrying the HLA DQB1*02 allele had a higher frequency of sicca syndrome. In ...
Faculty Collaboration Database
Garland JS, Alex CP, Pauly TH, Whitehead VL, Brand J, Winston JF, Samuels DP, and McAuliffe TL. A three-day course of ... Immunogenetic Studies of Autoimmune Chronic Active Hepatitis: HLA, Immunoglobulin Allotypes and Autoantibodies. ... Tissue Antigens 31: 243-249, 1988.. 14. Horbar JD, McAuliffe TL, Adler SM, Albersheim S, Cassady G, Edwards W, Jones R, ... HLA, Immunoglobulin Allotypes and Auto-antibodies. Hepatology 7(6): 1305-1310, 1987. ...
Antibody - Wikipedia
Antibody-antigen interactions[edit]. The antibodys paratope interacts with the antigens epitope. An antigen usually contains ... Plosker GL, Figgitt DP (2003). "Rituximab: a review of its use in non-Hodgkins lymphoma and chronic lymphocytic leukaemia". ... Functions mainly as an antigen receptor on B cells that have not been exposed to antigens.[28] It has been shown to activate ... Rh factor, also known as Rh D antigen, is an antigen found on red blood cells; individuals that are Rh-positive (Rh+) have this ...
Publications: UMM Universitätsmedizin Mannheim
Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP. Nutrients. 2020 Mar 24;12(3): ... Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies. Neumaier M et al ... A paired-kidney allocation study found superior survival with HLA-DR compatible kidney transplants in the Eurotransplant Senior ... MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in ...
IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence,...
A trend for an increase in HLA-DR expression, which has slower induction dynamics, can also be noted in the NK cells treated ... Although studies shown here target the CD33 antigen in myeloid tumors, the IL15 TriKE platform can easily be adapted to target ... DP. , Finke. L. , et al Safety, pharmacokinetics, and biological pharmacodynamics of the immunocytokine EMD 273066 (huKS-IL2): ... Purpose: The effectiveness of NK cell infusions to induce leukemic remission is limited by lack of both antigen specificity and ...
Publications | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP
Role of HLA-B and C alleles in development of psoriasis in patients from North India. Tissue Antigens 51: 618-622. http://dx. ... http://dx.doi.org/10.1016/S1047-2797(01)00310-6 Guimaraes DP and Hainaut P (2002). TP53: a key gene in human cancer. Biochimie ... D. Wu, Wu, Y., Liu, J. L., Wang, B., and Zhang, X. D., "Association between HLA-Cw*0602 polymorphism and psoriasis risk: a meta ... 2005a). HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene ...
The Clearity Foundation | Find Clinical Trials
Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays | eLife
1995) New HLA-DPB1 alleles generated by interallelic gene conversion detected by analysis of sperm Nature Genetics 10:407-414. ... such as the human leukocyte antigen gene family (Zangenberg et al., 1995) or the transmembrane protein gene cassettes of some ... Bruno DP. * Martens CA. * Porcella SF. * Moss B. (2010) Simultaneous high-resolution analysis of vaccinia virus and host cell ...
Primary bronchiolar disorders: diagnosis and treatment
Neuroinflammation and psychiatric illness | Journal of Neuroinflammation | Full Text
Steiner J, Mawrin C, Ziegeler A, Bielau H, Ullrich O, Bernstein HG, Bogerts B: Distribution of HLA-DR-positive microglia in ... Hof PR, Haroutunian V, Friedrich VL Jr, Byne W, Buitron C, Perl DP, Davis KL: Loss and altered spatial distribution of ... In the animal models, the interaction between TCR of activated T lymphocytes and their cognate antigen presenting cells ... Experimental data suggest that the interaction between T cell receptors of activated T lymphocytes and their cognate antigen ...
Biomarkers for immunotherapy in bladder cancer: a moving target | Journal for ImmunoTherapy of Cancer | Full Text
A subset of 18 specific genes including interferon-gamma signaling (IDO1 and STAT1), antigen presentation (HLA-DRB1, HLA-DQA1, ... Carbone DP, Reck M, Paz-Ares L, et al. First-line Nivolumab in stage IV or recurrent non-small-cell lung cancer. N Engl J Med. ... IFN-g stimulates the expression of HLA molecules and proteasome components including PSMB10 (3). Finally, IFN-g upregulates a ... HLA-E), NK T cell signaling (NKG7, CMKLR1), and additional immunomodulatory proteins (Fig. 4b) were tested in a larger cohort ...
2015 - IRBDMR
Role of urinary LAM antigen (lipoarabinomannan) test in diagnosis of. extra-pulmonary tuberculosis in HIV infected patients. 7 ... HLA Class I and Class II alleles and haplotypes frequencies in Kachin, Mon ... Efficacy and safety of artemether- lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated ...
NetMHCpan-4.0: Improved Peptide-MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data...
Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA ... HLA-DP and HLA-DQ. ... HLA-A*02:01 has a strong preference for 9-mers only, and HLA-B* ... Representative alleles were assigned for entries where only supertypes were listed (e.g., HLA-A*26:01 for HLA-A26). Thus, there ... Unsupervised HLA peptidome deconvolution improves ligand prediction accuracy and predicts cooperative effects in peptide-HLA ...
1 - ANALYSIS OF TRADERS BINARY APPLE
215 T lymphocyte One of two types of lymphocytes: a killer T cell that interacts directly with antigen-bearing cells and is ... 1 gl solution of rhodamine B R. The following HLA code implements this Boolean expression using both forms:7 Complex expression ... Unicondy- lar fractures may be hard to identify radiographical- ly, particularly on the frontal or dorsi-palmar (DP) view. ...