... suggesting that memory acquisition is linked to histone replacement. The role of H3.3 histone replacement in transcriptional ... S5 E-G). Another histone mark, H3K4me1, showed a modest correlation (SI Appendix, Fig. S5 E-H). Together, transcriptional ... 2009) Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459:108-112. ... S4 D-H) (12). Other histone marks representing expressed genes such as H3K4me3 and H4ac did not show a clear correlation with ...

A) Primary structure of histone H1 (Upper) and schematics of the histone H1 deletion mutants (Lower). (B) 15% SDS-PAGE of ... 1989) Laser-induced crosslinking of histones to DNA in chromatin and core particles: implications in studying histone-DNA ... 2005) Linker histone variants control chromatin dynamics during early embryogenesis. Proc Natl Acad Sci USA 102(16):5697-5702. ... 1987) Accessibility of the globular domain of histones H1 and H5 to antibodies upon folding of chromatin. Eur J Biochem 167(2): ...

Immunoblotting was performed using anti-COP1, anti-histone 3, and anti-tubulin antibodies. (G) Immunoblot analysis showing the ...

2006) The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters ... Epigenetic mechanisms, including covalent DNA and histone modifications, as well as chromatin remodeling, have been shown to be ... such as interaction of DNMTs with histone modifiers or transcription factors that can recognize specific genomic loci (38⇓⇓-41 ... a histone-lysine N-methyltransferase enzyme) (Fig. 6F). Notably, antibodies against all three DNMTs retrieved significant ...