Loading...
*  Abstract 1772: p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression. | Cancer Research
Abstract 1772: p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression.. Hong Zheng and Jiandong ... Constitutive heterochromatin is important for maintaining chromosome stability but also delays the repair of DNA double strand ... Depletion of JMJD2b or sustained expression of SUV39H1 delays the repair of heterochromatin DNA and reduces clonogenic survival ... p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression. [abstract]. In: Proceedings of the ...
http://cancerres.aacrjournals.org/content/73/8_Supplement/1772
*  Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability | Journal of Cell Science
Drosophila CAF-1 p180 is involved in ectopic heterochromatin formation. It is known that heterochromatin formation is a complex ... a constitutive heterochromatin component, has been well documented for its function in heterochromatin formation (Clark and ... pericentric heterochromatin is dependent on heterochromatin protein 1 (HP1) (Eissenberg and Elgin, 2000) and intercalary ... participates in the process of heterochromatin formation and functions to maintain pericentric heterochromatin stability. We ...
http://jcs.biologists.org/content/123/16/2853
*  The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres |...
NoRC establishes pericentromeric heterochromatin. As NoRC promotes heterochromatin formation and silencing of rRNA genes, we ... HP1 links centromeric heterochromatin to centromere cohesion in mammals Qi Yi, Qinfu Chen, Cai Liang, Haiyan Yan, Zhenlei Zhang ... Deng Z, Norsen J, Wiedmer A, Riethman H, Lieberman PM (2009) TERRA RNA binding to TRF2 facilitates heterochromatin formation ... Folco HD, Pidoux AL, Urano T, Allshire RC (2008) Heterochromatin and RNAi are required to establish CENP‐A chromatin at ...
http://embor.embopress.org/content/14/8/704
*  Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos. | Passport
Heterochromatin protein 1 is associated with centromeric heterochromatin in Drosophila, mice, and humans. Loss of function ... Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos. ... These heterochromatin protein 1 mutations not only suppress this position-effect variegation, but also cause recessive ... In this study, we analyze the latter phenotype in the hope of gaining insight into heterochromatin function. In our analyses of ...
https://passport.as.uky.edu/heterochromatin-protein-1-required-correct-chromosome-segregation-drosophila-embryos
*  IDEALS @ Illinois: Role of ORCA and ORC in chromatin organization and DNA replication
Changes in heterochromatin structure due to loss of ORCA affects replication timing, preferentially at the late-replicating ... The role of ORCA and ORC in heterochromatin organization remained elusive. In Chapter II, I describe my efforts to understand ... Heterochromatin mostly constitutes tightly packaged DNA, decorated with repressive histone marks, including histone H3 ... While constitutive heterochromatin enriched with H3K9me3 and H4K20me3 occur within repetitive elements, including centromeres ...
https://www.ideals.illinois.edu/handle/2142/90477
*  What Is Heterochromatin? (with pictures)
Heterochromatin is a type of tightly-coiled chromosomal material that carries genes. Although heterochromatin is largely inert ... It exists in two forms - constitutive and facultative heterochromatin. Constitutive heterochromatin is considered to be fixed ... The presence of heterochromatin in the body may have direct correlation to the aging process. It was once believed that ... Heterochromatin is a form of tightly-coiled chromosomal material that carries genes, and is considered to be largely inert ...
http://www.wisegeek.com/what-is-heterochromatin.htm
*  Making and breaking heterochromatin | Max-Planck-Gesellschaft
Institute for Epigenetics and Immunobiology discover two further mechanisms necessary for the formation of heterochromatin ... Heterochromatin breaks down and the heterochromatin regions can be read. "Our experiments show that Prdm3 and Prdm16 attach a ... Heterochromatin must be associated with this layer of lamina proteins at the inner nuclear membrane. "The cell apparently ... However, we do not know whether the destruction of the lamina is triggered by the loss of heterochromatin or by the absence of ...
https://www.mpg.de/6366051/heterochromatin-formation
*  Meiotic Crossing Over in Maize Knob Heterochromatin | Genetics
Chiasmata observed in heterochromatin were suggested to have formed in tiny islands of euchromatin within heterochromatin or in ... Heterochromatin stickiness. Bivalent associations in heterochromatin at late prophase I were proposed to be due not to ... Constitutive heterochromatin (subsequently referred to simply as heterochromatin) is most commonly found at telomeres and ... First, crossover suppression need not be mediated by heterochromatin. For example, centromeres without heterochromatin can ...
https://www.genetics.org/content/205/3/1101
*  pericentric heterochromatin Gene Ontology Term (GO:0005721)
The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products across databases. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated gene data at MGI are provided in Term Detail reports.
http://www.informatics.jax.org/vocab/gene_ontology/GO:0005721
*  Heterochromatin Organization Pathway Bioinformatics: Novus Biologicals
Learn more about the Heterochromatin Organization Pathway from related diseases, pathways, genes and PTMs with the Novus ... Explore more on Heterochromatin Organization below! For more information on how to use Laverne, please read the How to Guide.. ... The Heterochromatin Organization Pathway has been studied in relation to diseases such as: *Pyotraumatic Dermatitis ... Heterochromatin Organization Pathway Bioinformatics. Disease and disorder research has been conducted in relation to the ...
https://www.novusbio.com/pathways/heterochromatin-organization
*  Monoclonal Antibody Centric Heterochromatin from Cell Signaling Technology
Monoclonal Antibody Centric Heterochromatin. Monoclonal Antibody - HP1β (D2F2) XP® Rabbit mAb, UniProt ID P83916, Entrez ID ... Background: Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing ... and heterochromatin proteins (HP1, SUV39H1), to maintain proper levels of DNA methylation and facilitate gene silencing (3-8). ... and heterochromatin proteins (HP1, SUV39H1), to maintain proper levels of DNA methylation and facilitate gene silencing (3-8). ...
https://www.cellsignal.com/1/3/monoclonal-antibody-centric-heterochromatin
*  Making and breaking heterochromatin - Healthcanal.com : Healthcanal.com
Heterochromatin breaks down and the heterochromatin regions can be read. "Our experiments show that Prdm3 and Prdm16 attach a ... Heterochromatin must be associated with this layer of lamina proteins at the inner nuclear membrane. "The cell apparently ... However, we do not know whether the destruction of the lamina is triggered by the loss of heterochromatin or by the absence of ... "In heterochromatin, the binding sites for transcription factors are distributed more randomly, so that they cannot reinforce or ...
https://www.healthcanal.com/genetics-birth-defects/32473-making-and-breaking-heterochromatin.html
*  SET domain proteins modulate chromatin domains in eu- and heterochromatin | SpringerLink
... and heterochromatin - a role consistent with their modular structure, which combines the SET domain with additional sequence ...
https://link.springer.com/article/10.1007/s000180050127
*  Phase separation drives heterochromatin domain formation - BioPortfolio.com
Constitutive heterochromatin is an important component of eukaryotic genomes that has essential roles in nuclear architecture, ... Constitutive heterochromatin is an important component of eukaryotic genomes that has essential roles in nuclear architecture, ... Heterochromatin is highly enriched for repetitive sequences, and is defined epigenetically by methylation of histone H3 at ... partner heterochromatin protein 1 (HP1). A prevalent view of heterochromatic silencing is that these and associated factors ...
https://www.bioportfolio.com/news/article/3195667/Phase-separation-drives-heterochromatin-domain-formation.html
*  Constitutive heterochromatin banding - Biology-Online Dictionary
The domains of constitutive heterochromatin are the regions of DNA in the chromosomes of eukaryotes. Most of them are found at ... cytogenetics) A selective banding technique wherein a banding pattern is produced in the constitutive heterochromatin located ... The different types of banding are Giemsa (G-) banding, reverse (R-) banding, constitutive heterochromatin (C-) banding, ... C-banding is a cytogenetic banding technique that employs Giemsa stain that binds to constitutive heterochromatin. ...
https://www.biology-online.org/dictionary/C_banding
*  Drosophila longevity is not affected by heterochromatin-mediated gene silencing. - PubMed - NCBI
Heterochromatin-mediated gene silencing was then modulated without directly influencing HP1 as well as the deacetylases, again ... Drosophila longevity is not affected by heterochromatin-mediated gene silencing.. Frankel S1, Rogina B. ... Because the Drosophila forms of each protein can silence genes in either euchromatin or heterochromatin, we determined whether ... When silencing was increased and decreased using mutations that affect heterochromatin protein 1 (HP1), but have no direct ...
https://www.ncbi.nlm.nih.gov/pubmed/15659213
*  Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster. | Genetics
Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster.. A R Lohe, A J Hilliker and P A Roberts ... Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster.. A R Lohe, A J Hilliker and P A Roberts ... Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster.. A R Lohe, A J Hilliker and P A Roberts ... Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster. Message Subject (Your Name) has forwarded ...
http://www.genetics.org/content/134/4/1149
*  Frontotemporal Dementia, Manifested as Schizophrenia, with Decreased Heterochromatin on Chromosome 1
Chromosomal analysis was conducted and revealed decrease in length of heterochromatin on the long arm of chromosome 1 (46, XX, ... Frontotemporal Dementia, Manifested as Schizophrenia, with Decreased Heterochromatin on Chromosome 1. Philippos Gourzis,1 Maria ...
https://www.hindawi.com/journals/crips/2012/937518/abs/
*  Establishment and Maintenance of a Heterochromatin Domain | Science
Establishment and Maintenance of a Heterochromatin Domain. By Ira M. Hall, Gurumurthy D. Shankaranarayana, Ken-ichi Noma, ... Establishment and Maintenance of a Heterochromatin Domain. By Ira M. Hall, Gurumurthy D. Shankaranarayana, Ken-ichi Noma, ... Establishment and Maintenance of a Heterochromatin Domain Message Subject. (Your Name) has forwarded a page to you from Science ... Here, we study a 20-kilobase silent domain at the mating-type region of fission yeast as a model for heterochromatin formation ...
https://science.sciencemag.org/content/297/5590/2232
*  Difference Between Euchromatin and Heterochromatin | Difference Between
Euchromatin vs Heterochromatin Our body is composed of billions of cells. A typical cell contains a nucleus, and the nucleus ... The euchromatin is less intense than heterochromatin. This only indicates that heterochromatin has tighter DNA packaging. To ... Euchromatin vs Heterochromatin. Our body is composed of billions of cells. A typical cell contains a nucleus, and the nucleus ... Heterochromatin is only found in eukaryotes. When stained and observed under an optical microscope, euchromatin resembles light ...
http://www.differencebetween.net/science/biology-science/differences-between-euchromatin-and-heterochromatin/
*  Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. - PubMed - NCBI
Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens.. Maze I1, Feng J, ... C) Altered heterochromatin domain numbers are consistent with altered levels of H3K9me3 after repeated cocaine at 1 and 24 h. ... Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proc Natl Acad Sci U S A ... Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proc Natl Acad Sci U S A ...
https://www.ncbi.nlm.nih.gov/pubmed/?term=Cocaine+dynamically+regulates+heterochromatin+and+repetitive+element+unsilencing+in+nucleus+accumbens
*  DSpace@MIT: Differential Maintenance of DNA Sequences in Telomeric and Centromeric Heterochromatin
Differential Maintenance of DNA Sequences in Telomeric and Centromeric Heterochromatin. Download Author: DeBaryshe, P. G.; ... Repeated DNA in heterochromatin presents enormous difficulties for whole-genome sequencing; hence, sequence organization in a ... Differential Maintenance of DNA Sequences in Telomeric and Centromeric Heterochromatin. Research and Teaching Output of the MIT ... "Differential Maintenance of DNA Sequences in Telomeric and Centromeric Heterochromatin." Genetics 187.1 (2010): 51-60. Web. ...
http://dspace.mit.edu/handle/1721.1/76257
*  1.4 Chromatin compaction - heterochromatin versus euchromatin - Week 1 - Introduction to Epigenetic Control | Coursera
heterochromatin. So again, according to its name, it suggests that the constitutive of heterochromatin is the same in every ... Constitutive Heterochromatin. So we are going to go through and explain what each of these mean. So Facultative Heterochromatin ... heterochromatin have a different set of epigenetic marks. So there are different punctuation marks if you like that are ... constitutive heterochromatin performs a structural role. So you remember that I mentioned that there are epigenetic marks that ...
https://www.coursera.org/lecture/epigenetics/1-4-chromatin-compaction-heterochromatin-versus-euchromatin-nSL07
*  HP1BP3 - Heterochromatin protein 1-binding protein 3 - Homo sapiens (Human) - HP1BP3 gene & protein
Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 ... Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 ... Heterochromatin protein 1-binding protein 3Add BLAST. 552. Amino acid modifications. Feature key. Position(s). Description ... Heterochromatin protein 1-binding protein 3. Alternative name(s):. Protein HP1-BP741 Publication. ,p>Manually curated ...
https://www.uniprot.org/uniprot/Q5SSJ5
*  LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC | PNAS
Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin ... LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC. Joshua S. Mylne, ... Another key component in epigenetic silencing in Drosophila and vertebrates is HETEROCHROMATIN PROTEIN (HP)1. HP1 was shown to ... VRN1/GFP associates with mitotic chromosomes and not heterochromatin. (A) A genomic VRN1/GFP construct was produced by mutating ...
http://www.pnas.org/content/103/13/5012.long