HCT116 is a human colon cancer cell line used in therapeutic research and drug screenings. HCT116 cells have a mutation in ... it was found that the knockout of MARCH2 limited growth of HCT116 cells via stress on the endoplasmic reticulum. HCT116 cells ... HCT116 cells can also function in xenografts, with docetaxel, 5-FU, and flavopiridol limiting tumor growth in vitro. The HCT116 ... HCT116 cells remain arrested in the G1 phase. The proliferation of HCT116 colonies was found to be inhibited by 5-Fu/P85 ...

Flow cytometry analysis was employed to detect the size and granularity of HCT116 cells. Western blot was performed to measure ... Transmission electron microscopy was used to analyze ultrastructural and evaluate morphologic feature of HCT116 cells after ... Our data suggest that ,sup,125,/sup,I seeds radiation can induce paraptosis-like cell death via PI3K/AKT signaling pathway. ... We found that ,sup,125,/sup,I seeds radiation activated PI3K/AKT signaling pathway and could trigger paraptosis-like cell death ...

... small cell lung cancer), XWLC-05 (Yunnan lung cancer cell line), CNE (human nasopharyngeal carcinoma cell line), HCT-116 (human ... human lung epithelial cell line), an inhibitory effect. Finally in colon cancer cell line (HCT-116) we observed an initially ... Treatment of A-549 (small cell lung cancer) cells with E. senticosus methanolic extract showed a concentration-dependent ... Next, in CNE (human nasopharyngeal carcinoma cell line) there was a dose dependent proliferative response, whereas in Beas-2 ( ...

Discover the cytotoxic potential of Canarium odontophyllum stem bark extracts against colorectal carcinoma cells. Learn about ... against human colorectal cancer cell line HCT 116 and paves way for further investigation in view of its mode of cancer cell ... against Human Colorectal Carcinoma HCT 116 Cell Line. American Journal of Plant Sciences, 5, 3925-3933. doi: 10.4236/ajps. ... Payne, G.F., Bringi, V., Prince, C. and Shuler, M.L. (1992) Plant Cell and Tissue Culture in Liquid Systems. Hanser Publication ...

Results revealed that essential oils significantly reduced the viability of MCF-7, HFS and HCT116 cells in a concentration- ... Results revealed that essential oils significantly reduced the viability of MCF-7, HFS and HCT116 cells in a concentration- ... nbsp; Key words: Anticancer activity, chemical composition, essential oil, cytotoxic effects, cell lines,  Mcf-7, Hfs, ... nbsp; Key words: Anticancer activity, chemical composition, essential oil, cytotoxic effects, cell lines,  Mcf-7, Hfs, ...

Cell cycle analysis by PI staining. HCT 116 colon carcinoma cells at a density of 2×105 cells/well were seeded in 6-well plates ... A) Apoptotic cell death was determined by using Cell Death ELISA Plus assay following exposure of HCT 116 colon carcinoma cells ... A) GFP-LC3 in purvalanol-treated HCT 116 colon cancer cells. Following a 24 h transfection of the HCT 116 colon cancer cells ... inhibits cell proliferation and induces cell death in a dose- and time-dependent manner in the HCT 116 colon cancer cells. (A) ...

HCT116 cells at 20 to 100 uM by SRB assay. ...

We assure the cell line is free of mycoplasma and with good viability. Free technical guidance e.g. tips for cell culture will ... This cell line is validated by Sanger sequencing. A validation report and STR authentication report will be provided. ... HCT116) is constructed based on (1) the optimal design of the Red Cotton System, (2) CRISPR-U™ technology with efficiency 10-20 ... Cell line. SLC38A9 Knockout cell line(HCT116) Cell Type. Human Colon Cancer Cell Line ...

HCT116 cell proliferation was assessed by conducting crystal violet and BrdU assays. To assess the effects of EOPK on cell ... EOPK significantly decreased HCT116 cell proliferation and migration, and induced G1 arrest without affecting normal cells. ... Additionally, EOPK suppressed the expression of PAK1, and decreased ERK and AKT phosphorylation in HCT116 cells. Finally, EOPK ... Our studies indicate that EOPK significantly reduced proliferation and migration of colorectal cancer cells. Furthermore, EOPK ...

Lyophilized exosomes from HCT116 cell line 2x30µg vials quantity. Add to cart. SKU: HBM-HCT-30/2 Categories: Exosome Products, ... Exosome Products / Exosome Standards and Microvesicles / Standards from Cell conditioned Medium / Colorectal cancer. ...

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Our experiments indicate that colon cancer cells are dependent on both β-catenin-dependent and -independent Wnt signaling ... LCOR and REEP1 as non-canonical target genes in various colon cancer cells. Moreover, non-canonical Wnt target genes are ... Wnt target gene signature in order to understand the functional significance of non-canonical signaling in colon cancer cells. ... the ligands Wnt5a/b are upstream regulators of the non-canonical signature and moreover regulate proliferation of cancer cells ...

... chloroform and ethanol extracts of Gracilaria verrucosa were evaluated against colorectal HCT-116 cells by MTT cell ... chloroform and ethanol extracts of Gracilaria verrucosa were evaluated against colorectal HCT-116 cells by MTT cell ... chloroform and ethanol extracts of Gracilaria verrucosa were evaluated against colorectal HCT-116 cells by MTT cell ... chloroform and ethanol extracts of Gracilaria verrucosa were evaluated against colorectal HCT-116 cells by MTT cell ...

Human VIM knockout HCT116 cell line (ab289211) Description:. Human VIM knockout HCT116 cell line ... Cell lines and Lysates. Multiplex Assays. By research area. Cancer. Cardiovascular. Cell Biology. Epigenetics. Metabolism. ... Cell and tissue imaging tools. Cellular and biochemical assays. By product type. Proteins and Peptides. Proteomics tools. ...

Human HK2 (Hexokinase II) knockout HCT116 cell line (ab273721) Specific References (1) ... Cell lines and Lysates. Multiplex Assays. By research area. Cancer. Cardiovascular. Cell Biology. Epigenetics. Metabolism. ... Cell and tissue imaging tools. Cellular and biochemical assays. By product type. Proteins and Peptides. Proteomics tools. ... Serum, Cell culture extracts, Tissue Extracts, Hep Plasma, EDTA Plasma, Cit plasma ...

Thus, we conclude that the anticancer effect of purvalanol in HCT 116 cells was due to ER stress-mediated apoptosis; however, ... Fifteen micromoles of purvalanol induced a reduction in cell viability by 20 and 35% within 24 and 48 h, respectively. HCT 116 ... eIF-2α phosphorylation and ATF-6 cleavage at early time-points in the HCT 116 colon cancer cells. Moreover, we determined that ... breast and colon cancer cell lines. Various physiological and pathological conditions such as glucose starvation, inhibition of ...

NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. Alice Y. Chuang, Jim C. Chuang, Zili Zhai, Feng ... NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. / Chuang, Alice Y.; Chuang, Jim C.; Zhai, Zili et ... NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. Inflammatory bowel diseases. 2014 Jan;20(1):126- ... NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. In: Inflammatory bowel diseases. 2014 ; Vol. 20, ...

Gelam (Melaleuca sp.) honey demonstrates antiproliferative effects on colon cancer cell lines (HCT116) ... ESHAK, ZOLKAPLI BIN (2012) Gelam (Melaleuca sp.) honey demonstrates antiproliferative effects on colon cancer cell lines ( ...

Tumor Cells Products from Applied Biological Materials (ABMGood) in Stock in London & Brussels for UK & Europe Distribution. ... abm , HCT116 Cells , T8240Organism:HumanSource Organ:ColonImmortalization Method:N/AGrowth Properties:AdherentMorphology: ... abm , RWV366T Cells , T8250Organism:HumanSource Organ:Clear cell renal cell carcinomaImmortalization Method:SpontaneousGrowth ... abm , KIJ265T Cells , T8249Organism:HumanSource Organ:Clear cell renal cell carcinomaImmortalization Method:SpontaneousGrowth ...

Genetic ablation of TMEM9 inhibits colorectal cancer cell proliferation in vitro, ex vivo and in vivo mouse models. Moreover, ... Each CRC cell line (shCtrl versus shTMEM9) was analyzed for cell proliferation by cell counting. IF staining of HCT116 (shCtrl ... HCT116 cells were stably transduced with lentiviruses encoding six different shRNAs and analyzed by IB (g). Eleven CRC cells ... Co-IP of HCT116 cells (TMEM9 WT versus KO). IgG H.C.: immunoglobulin heavy chain. Experiments were performed three times with ...

All new cyanine dyes showed potent micromolar antiproliferative activity against cancer cell lines, making them promising ... Firstly, 4a-4e compounds were tested for their antiproliferative activity against three human cancer cell lines: HCT 116 ( ... had selective antiproliferative affinity for tumor cells compared to healthy cells and efficiently entered cells, emitting a ... The panel cell lines were inoculated onto a series of standard 96-well microtiter plates on day 0, at 1 × 104 to 3 × 104 cells/ ...

Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. ... Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. / ... Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. In ... Taken together, our findings suggest that denbinobin induces apoptosis of human colorectal cancer HCT-116 cells via DNA damage ...

For this function, we ready soluble and chromatin ingredients from individual colorectal tumor HCT116 cells (Body 1figure ... For this function, we prepared soluble and chromatin ingredients from individual colorectal cancers HCT116 cells (Figure ... For this function, we prepared soluble and chromatin ingredients from individual colorectal cancers HCT116 cells (Figure ... For this function, we prepared soluble and chromatin ingredients from individual colorectal cancers HCT116 cells (Figure ...

... the genetic function algorithm method to model the cytotoxicity of the compounds against the HCT116 colorectal cancer cell line ... design and molecular docking study of CDK2 inhibitors with potent cytotoxic activity against HCT116 colorectal cancer cell line ...

... of 5-fluorouracil cocrystals with novel organic acids as coformers and anticancer evaluation against HCT-116 colorectal cell ... of 5-fluorouracil cocrystals with novel organic acids as coformers and anticancer evaluation against HCT-116 colorectal cell ...

DOX-CBs have a better cytotoxic effect and induced ROS and reduced NO levels in HCT-116 cells. Conclusion: The obtained results ... In vitro activity of doxorubicin-loaded cubosomes was studied on HCT-116 cells. Results: The prepared cubosomes have the ... Keywords: Doxorubicin, HCT-116 cells, Pluronic F127, In vitro activity, Cubosomes, Entrapment efficiency. ... and Evaluation of Doxorubicin-loaded Cubosome as a Cytotoxic Potentiator against HCT-116 Colorectal Cancer Cells. ...

The cell cycle analysis showed a significant inhibition of the HCT 116 cells proliferation following FBX-EMLs treatment ... HCT 116) cells. The optimized FBX-EMLs formula had an improved half maximal inhibitory concentration (IC50), about 4-fold lower ... The enhanced cytotoxic and pro-apoptotic effects of optimized simvastatin-loaded emulsomes on MCF-7 breast cancer cells June ... The optimized formula was also able to significantly increase the percentage of cell population in both early and late stages ...

Human HCT116 colon cancer cell lines were transfected with either XIAP (X) or luciferase (L) shRNA. The expression profiles of ... stably expressed in a parent HCT116 human colon cancer cell line, a series of clones have been developed. XIAP mRNA levels were ... cell lines. Immunoblot analysis showed a 67-89% reduction in XIAP protein in X cell lines compared to L. RNA was analysed by ... Finally, XIAP knockdown sensitises cells to radiotherapy by 20%, to recombinant TRAIL by a 3-fold factor, and to paclitaxel and ...

Manuka honey induces HCT-116 and LoVo cell death partly by enhancing oxidative stress.Apr 11, 2018. ... This is the first report of the antimicrobial activity of Manuka honey against a cell-wall free bacterial pathogen.Dec 18, 2016 ... Manuka honey exhibited a marked potential to protect DNA of whole blood cells from oxidative damage induced by hydrogen ... Manuka honey inhibits cell division in methicillin-resistant Staphylococcus aureus.Nov 01, 2011. ...

Bioluminescence detecting with organic photodetectors in HCT-116 colon cancer cells. Prof. Zhang is leading an ... Progress in research into organic solar cells has been rapid in recent years. These cells are environmentally sensitive, can be ... Zhangs work centers on organic based solar cells made from organic solutions which, compared to silicon based solar cells, ... have developed organic solar cells with a significantly lower driving force and faster charge separation than previous cells. ...