AGTPBP1 (gene) - Wikipedia
ATP/GTP binding protein 1 is gene that encodes the protein known as cytosolic carboxypeptidase 1 (CCP1), originally named NNA1 ... "Entrez Gene: ATP/GTP binding protein 1". Retrieved 2018-06-13. Fernandez-Gonzalez A, La Spada AR, Treadaway J, Higdon JC, ... a novel ATP/GTP-binding protein related to zinc carboxypeptidases". Mol Cell Neurosci. 16 (5): 578-96. doi:10.1006/mcne. ... with alleles containing a zinc carboxypeptidase domain and an ATP/GTP binding motif, a protein first identified in alpha- ...
GTPBP4 - Wikipedia
Nucleolar GTP-binding protein 1 is a protein that in humans is encoded by the GTPBP4 gene. GTPases function as molecular ... a GTP-binding protein that interacts with the neurofibromatosis 2 protein". Mol. Cell. Biol. 27 (6): 2103-19. doi:10.1128/MCB. ... "Entrez Gene: GTPBP4 GTP binding protein 4". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap ... The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, ...
RHEB - Wikipedia
... the protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is ... allowing RHEB to activate the protein. RHEB acts as an activator for mTORC1 in its GTP-bound form, therefore GTP-bound RHEB ... is a GTP-binding protein that is ubiquitously expressed in humans and other mammals. The protein is largely involved in the ... The protein is a lipid-anchored, cell-membrane protein with five repeats of the RAS-related GTP-binding region. Also present ...
GTPBP1 - Wikipedia
GTP-binding protein 1 is a protein that in humans is encoded by the GTPBP1 gene. This gene is upregulated by interferon-gamma ... "Entrez Gene: GTPBP1 GTP binding protein 1". Goretzki L, Mueller BM (1999). "Low-density-lipoprotein-receptor-related protein ( ... and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has ... interacts with a GTP-binding protein". Biochem. J. 336 (2): 381-6. doi:10.1042/bj3360381. PMC 1219882. PMID 9820815. Dunham I, ...
Nucleoside triphosphate - Wikipedia
G proteins can bind either GDP or GTP. When bound to GDP, G proteins are inactive. When a ligand binds a GPCR, an allosteric ... GTP is essential for signal transduction, especially with G proteins. G proteins are coupled with a cell membrane bound ... GTP activates the alpha subunit of the G protein, causing it to dissociate from the G protein and act as a downstream effector ... The activity site can bind either ATP or dATP. When bound to ATP, RNR is active. When ATP or dATP is bound to the S site, RNR ...
OLA1 - Wikipedia
"Entrez Gene: GTPBP9 GTP-binding protein 9 (putative)". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace ... "Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins". J Biol Chem. 282 (27): 19928-37. doi:10.1074 ... Ola1 belongs to the protein family of Obg-like GTPases but defines an exceptional example of a protein that has evolved altered ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ...
RAB14 - Wikipedia
"Small GTP-binding proteins in human endothelial cells". Br J Haematol. 103 (1): 15-9. doi:10.1046/j.1365-2141.1998.00965.x. ... Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene. GRCh38: Ensembl release 89: ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ...
RAB6A - Wikipedia
Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to ... Goud B, Zahraoui A, Tavitian A, Saraste J (1990). "Small GTP-binding protein associated with Golgi cisternae". Nature. 345 ( ... Karniguian A, Zahraoui A, Tavitian A (1993). "Identification of small GTP-binding rab proteins in human platelets: thrombin- ... Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome. Its ...
RAB2A - Wikipedia
The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding ... Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 ... Zahraoui A, Touchot N, Chardin P, Tavitian A (Jul 1989). "The human Rab genes encode a family of GTP-binding proteins related ... highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in ...
GNAI1 - Wikipedia
"GTP-binding proteins in human platelet membranes serving as the specific substrate of islet-activating protein, pertussis toxin ... Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene. Click on ... "Entrez Gene: GNAI1 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1". Schiaffino MV, ... "Identification of GTP-binding proteins in human glomeruli". Nihon Jinzo Gakkai Shi. 36 (1): 9-12. PMID 8107314. Law SF, Zaina S ...
DRG1 - Wikipedia
Developmentally-regulated GTP-binding protein 1 is a protein that in humans is encoded by the DRG1 gene. GRCh38: Ensembl ... Mahajan MA, Park ST, Sun XH (1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins". Oncogene. ... Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994). "A novel GTP-binding protein which is selectively repressed in ... Sazuka T, Tomooka Y, Ikawa Y, Noda M, Kumar S (Dec 1992). "DRG: a novel developmentally regulated GTP-binding protein". Biochem ...
ARF4 - Wikipedia
Shin OH, Ross AH, Mihai I, Exton JH (1999). "Identification of arfophilin, a target protein for GTP-bound class II ADP- ... A functionally conserved family of GTP-binding proteins". J. Biol. Chem. 266 (4): 2606-14. doi:10.1016/S0021-9258(18)52288-2. ... These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera ... "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966-70. doi: ...
ARF1 - Wikipedia
A functionally conserved family of GTP-binding proteins". J. Biol. Chem. 266 (4): 2606-14. doi:10.1016/S0021-9258(18)52288-2. ... a novel role for a GTP-binding protein". Cell. 67 (2): 239-53. doi:10.1016/0092-8674(91)90176-Y. PMID 1680566. S2CID 9766090. ... including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized ... The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of ...
AGBL4 - Wikipedia
ATP/GTP binding protein like 4 is a protein that in humans is encoded by the AGBL4 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: ATP/GTP binding protein like 4". Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, ...
RAB9A - Wikipedia
de Leeuw HP, Koster PM, Calafat J, Janssen H, van Zonneveld AJ, van Mourik JA, Voorberg J (1998). "Small GTP-binding proteins ... Ras-related protein Rab-9A is a protein that in humans is encoded by the RAB9A gene. RAB9A has been shown to interact with ... Orzaez D, de Jong AJ, Woltering EJ (2001). "A tomato homologue of the human protein PIRIN is induced during programmed cell ... Soldati T, Riederer MA, Pfeffer SR (1993). "Rab GDI: a solubilizing and recycling factor for rab9 protein". Mol. Biol. Cell. 4 ...
GTPBP3 - Wikipedia
"Entrez Gene: GTPBP3 GTP binding protein 3 (mitochondrial)". Li X, Guan MX (2002). "A human mitochondrial GTP binding protein ... The GTPBP3 gene encodes a GTP-binding protein that is evolutionarily conserved from bacteria to mammals and which is localized ... The GTPBP3 gene contains 10 exons, and encodes a ~44 kDa GTP-binding protein that is evolutionarily conserved from bacteria to ... Li X, Guan MX (Nov 2002). "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic ...
DRG2 - Wikipedia
Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene. The DRG2 gene encodes ... "Entrez Gene: DRG2 developmentally regulated GTP binding protein 2". Sprang SR (1998). "G proteins, effectors and GAPs: ... Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994). "A novel GTP-binding protein which is selectively repressed in ... Schenker T, Trueb B (Jun 1998). "Assignment of the gene for a developmentally regulated GTP-binding protein (DRG2) to human ...
GNAO1 - Wikipedia
1994). "Identification of GTP-binding proteins in human glomeruli". Nippon Jinzo Gakkai Shi. 36 (1): 9-12. PMID 8107314. ... 1991). "Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two ... Guanine nucleotide-binding protein G(o) subunit alpha is a protein that in humans is encoded by the GNAO1 gene. Mutations in ... Wu HC, Lin CT (1994). "Association of heterotrimeric GTP binding regulatory protein (Go) with mitosis". Lab. Invest. 71 (2): ...
Yoshito Kaziro - Wikipedia
Kaziro focused on GTP binding proteins, the role of GTPases in signal transduction, and the role of GTP in mRNA gene expression ... Kaziro focused on GTP mechanisms and proposed signaling pathways involved with GTP-binding proteins. He researched the role of ... the characterization of G nucleotide binding protein complexes, and the role the GTP hydrolysis in protein mechanisms. His ... In 1971, Kaziro led research on identifying the properties of the two H-GTP binding proteins in E. coli. Factor T is one of two ...
RAB15 - Wikipedia
Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889- ... Ras-related protein Rab-15 is a protein that in humans is encoded by the RAB15 gene. GRCh38: Ensembl release 89: ... Strick DJ, Elferink LA (2006). "Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling ... Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant ...
RAB40A - Wikipedia
Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889- ... Ras-related protein Rab-40A is a protein that in humans is encoded by the RAB40A gene. GRCh38: Ensembl release 89: ... "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem ... domain-containing proteins based on their Rab-binding activity". Genes Cells. 11 (9): 1023-37. doi:10.1111/j.1365-2443.2006. ...
GEM (gene) - Wikipedia
GTP-binding protein GEM is a protein that in humans is encoded by the GEM gene. The protein encoded by this gene belongs to the ... Ward Y, Yap SF, Ravichandran V, Matsumura F, Ito M, Spinelli B, Kelly K (Apr 2002). "The GTP binding proteins Gem and Rad are ... "Entrez Gene: GEM GTP binding protein overexpressed in skeletal muscle". Cohen L, Mohr R, Chen YY, et al. (1995). " ... Kelly K (2006). "The RGK family: a regulatory tail of small GTP-binding proteins". Trends Cell Biol. 15 (12): 640-3. doi: ...
Atlastin-1 - Wikipedia
Luan Z, Zhang Y, Liu A, Man Y, Cheng L, Hu G (October 2002). "A novel GTP-binding protein hGBP3 interacts with NIK/HGK". FEBS ... Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. Zhao X, Alvarado D, Rainier S, Lemons R, Hedera P, Weber ... protein atlastin". The Journal of Biological Chemistry. 278 (49): 49063-71. doi:10.1074/jbc.M306702200. PMID 14506257. ...
ARHGAP5 - Wikipedia
Foster R, Hu KQ, Shaywitz DA, Settleman J (1994). "p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly". Mol. ... Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene. Rho GTPase activating protein 5 ... a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding ... Chakravarty G, Roy D, Gonzales M, Gay J, Contreras A, Rosen JM (2000). "P190-B, a Rho-GTPase-activating protein, is ...
DNM2 - Wikipedia
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over ... Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that ... a member of the large GTP-binding protein family". Gene. 163 (2): 301-6. doi:10.1016/0378-1119(95)00275-B. PMID 7590285. Klocke ... Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1". J. Biol. Chem. 277 (31): 28238-46. doi: ...
GNAQ - Wikipedia
"Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50)". ... G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C- ... Receptor activation catalyzes the exchange of GDP for GTP bound to the inactive G protein alpha subunit resulting in a ... Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD (1995). "Expression of GTP-binding protein alpha subunits in human ...
MAP4K4 - Wikipedia
Luan Z, Zhang Y, Liu A, Man Y, Cheng L, Hu G (October 2002). "A novel GTP-binding protein hGBP3 interacts with NIK/HGK". FEBS ... "MAP4K4 - Mitogen-activated protein kinase kinase kinase kinase 4 - Homo sapiens (Human) - MAP4K4 gene & protein". www.uniprot. ... The MAP4K4 gene contains four binding sites for p53. Upon binding, p53 up-regulates MAP4K4 expression leading to the activation ... facilitates protein-protein interactions. Although it has been identified, its structural components and functionality are ...
RAB21 - Wikipedia
Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889- ... Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur J Cell Biol. 79 (5): 308-16. ... Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene. GRCh38: Ensembl release 89: ... 2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287- ...
RAB25 - Wikipedia
Pereira-Leal JB, Seabra MC (November 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): ... Goldenring JR, Shen KR, Vaughan HD, Modlin IM (1993). "Identification of a small GTP-binding protein, Rab25, expressed in the ... 1997). "Increased immunoreactivity for Rab11, a small GTP-binding protein, in low-grade dysplastic Barretts epithelia". Lab. ... Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene. It is thought to act as a promoter of ...
RALB - Wikipedia
"Entrez Gene: RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)". Simicek M, Lievens S, ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... Hsieh CL, Swaroop A, Francke U (1990). "Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein". Somat ... Jilkina O, Bhullar RP (1997). "Generation of antibodies specific for the RalA and RalB GTP-binding proteins and determination ...