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*  Institute of Cancer Research Repository - A Two-step Mechanism for the Folding of Actin by the Yeast Cytosolic Chaperonin
Closed research groups , Protein Folding & Assembly. Depositing User:. Users 10 not found.. ... A Two-step Mechanism for the Folding of Actin by the Yeast Cytosolic Chaperonin ... A Two-step Mechanism for the Folding of Actin by the Yeast Cytosolic Chaperonin. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (1). pp. ... Actin requires the chaperonin containing TCP1 (CCT), a hexadecameric ATPase essential for cell viability in eukaryotes, to fold ...
http://publications.icr.ac.uk/10418/
*  CCT3 - T-complex protein 1 subunit gamma - Bos taurus (Bovine) - CCT3 gene & protein
chaperonin-containing T-complex Source: UniProtKB ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for the ... section describes covalent linkages of various types formed between two proteins (interchain cross-links) or between two parts ... It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.,p>,a href='/help ... section describes covalent linkages of various types formed between two proteins (interchain cross-links) or between two parts ...
http://www.uniprot.org/uniprot/Q3T0K2
*  Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components
NATURE PUBLISHING GROUP , 2016. Vol. 6, no 28386 National Category Biophysics Identifiers. URN: urn:nbn:se:liu:diva-130280DOI: ... indicating that the mechanism of chaperonins is conserved during evolution. The chaperonin-bound MreB is also significantly ... Here, we study and compare the mechanisms of action of the GroEL/GroES and the TRiC chaperonin systems on MreB client protein ... Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components. Babu ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:950600
*  Biomolecules | Free Full-Text | The Role of Non-Native Interactions in the Folding of Knotted Proteins: Insights from...
The two proteins have a noticeably-good structural correspondence. A key difference is the presence of the two "knot-promoting ... Mallam, A.L.; Jackson, S.E. Knot formation in newly translated proteins is spontaneous and accelerated by chaperonins. Nat. ... with coarse-grained free energy plots obtained by MC and with experimental and computational results obtained by other groups ... The two proteins have a noticeably-good structural correspondence. A key difference is the presence of the two "knot-promoting ...
http://www.mdpi.com/2218-273X/4/1/1/htm
*  Functional Subunits of Eukaryotic Chaperonin CCT/TRiC in Protein Folding
3. Group II Chaperonin. In the group II chaperonins, both archaeal thermosome and eukaryotic chaperonin containing TCP-1 (CCT; ... chaperonins have been categorized into two groups, group I and group II [19-24]. Group I is found in all eubacteria and ... First, group I chaperonin is composed of identical subunits and has seven subunits per ring whereas group II chaperonin is ... Although group I chaperonin (GroEL) and group II chaperonin (CCT) have double ring structure and share sequence similarities, ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3268035/?lang=en-ca
*  Institute of Cancer Research Repository - The substrate recognition mechanisms in chaperonins.
... group-ii chaperonins; crystal- structure; archaeal chaperonin; beta-actin; alpha-lactalbumin; cytoplasmic chaperonin; molecular ... Although this general mechanism seems to apply to every chaperonin studied so far, there exist two different modes of ... The second type of mechanism has been described so far only for the cytosolic chaperonin CCT (Chaperonin Containing TCP-1) and ... The substrate recognition mechanisms in chaperonins Chaperonins are a family of proteins devoted to assisting the folding of ...
http://publications.icr.ac.uk/3728/
*  The Mechanism and Function of Group II Chaperonins (Journal Article) | DOE PAGES
Accepted Manuscript: The Mechanism and Function of Group II Chaperonins. Title: The Mechanism and Function of Group II ... The Mechanism and Function of Group II Chaperonins Journal Article Lopez, Tom ; Dalton, Kevin ; Frydman, Judith September 2015 ... Group II chaperonins, found in archaea and eukaryotes, contain a built-in lid that opens and closes over the central chamber. ... Group II chaperonins, found in archaea and eukaryotes, contain a built-in lid that opens and closes over the central chamber. ...
https://www.osti.gov/pages/biblio/1440550-mechanism-function-group-ii-chaperonins
*  Structure and Dynamics of Macromolecular Assemblies from Electron Microscopy Maps | IntechOpen
Dynamics of a group II chaperonin. Figure 9. Opening (top) and closing (bottom) of the chaperonin-folding chamber during the ... Dynamics of a group II chaperonin. The advance in electron microscopy experiment technology results in high-resolution maps, to ... By flexible fitting a group II chaperonin, mn-cpn, using maps from the EM databank: EMD-5138 (close state) and EMD-5140 (open ... We chose the open-close transitions of a group II chaperonin to demonstrate the application of this method. ...
https://www.intechopen.com/books/modern-electron-microscopy-in-physical-and-life-sciences/structure-and-dynamics-of-macromolecular-assemblies-from-electron-microscopy-maps/
*  Purification, crystallization, and preliminary X-ray crystallographic analysis of the Group III chaperonin from...
They consist of two back-to-back stacked... ... Chaperonins: The hunt for the group II mechanism. Arch. Biochem ... Chaperonins (CPNs) are megadalton sized ATP-dependent nanomachines that facilitate protein folding through complex cycles of ... They consist of two back-to-back stacked multisubunit rings. CPNs are usually classified into Group I and Group II. Here, we ... Crystal structures of a group II chaperonin reveal the open and closed states associated with the protein folding cycle. J. ...
https://link.springer.com/article/10.1007/s12275-016-6089-5
*  Publikationen
Gutsche I, Essen, L-O, Baumeister W (1999) - Group II chaperonins: new TRiC(k)s and turns of a protein folding machine. J Mol ... Nitsch M, Walz J, Typke D, Klumpp M, Essen L-O, Baumeister W (1998) - Archaeal group II chaperonin in an open conformation: the ... Dümmer M, Michalski C, Essen LO, Rath M, Galland P, Forreiter C (2016) - EHB1 and AGD12, two calcium-dependent proteins affect ... Klumpp M, Baumeister W, Essen, L-O (1997) - Structure of the substrate-binding domain of the thermosome, an archaeal groupII ...
https://www.uni-marburg.de/fb15/ag-essen/publikationen
*  KAKEN - Research Projects | Structural fluctuations and functional expression of the chaperonin complexes (KAKENHI-PLANNED...
Journal Article] Adaptation of a hyperthermophilic group II chaperonin to relatively moderate temperatures.2010. *. Author(s). ... Journal Article] Adaptation of a hyperthermophilic group II chaperonin to relatively moderate temperatures2010. *. Author(s). T ... conformational change and interaction between helical protrusions in the closure of the built-in lid of group II chaperonins. ... Conformational Change and Interaction between Helical Protrusions in the Closure of the Built-in Lid of Group II Chaperonins ...
https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-20107009/
*  Single particle analysis - Wikipedia
January 2010). "Mechanism of folding chamber closure in a group II chaperonin". Nature. 463 (7279): 379-83. doi:10.1038/ ... Depending on the sample or the desired results, various steps of two- or three-dimensional processing can be done. Biological ... Pairs of particles corresponding to the same object at two different tilts (tilt pairs) are selected, and by following the ... Methanococcus maripaludis chaperonin, reconstructed to 0.43 nanometer resolution. This bacterial protein complex is a machine ...
https://en.wikipedia.org/wiki/Single_particle_analysis
*  Table of Contents - December 23, 2003, 100 (26) | PNAS
Intracellular localization of a group II chaperonin indicates a membrane-related function Jonathan D. Trent, Hiromi K. Kagawa, ... A bacterial group II intron favors retrotransposition into plasmid targets Kenji Ichiyanagi, Arthur Beauregard, and Marlene ... MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation Yi Wang and Jun Qin ... Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast ...
http://www.pnas.org/content/100/26/
*  Cellular Proteomes Drive Tissue-Specific Regulation of the Heat Shock Response | G3: Genes | Genomes | Genetics
2015 The mechanism and function of group II chaperonins. J. Mol. Biol. 427(18): 2919-2930. ... TRiC/CCT is the cytoplasmic chaperonin in eukaryotic cells that contains two hetero-oligomeric rings with eight subunits each. ... One set of new regulators that we identified contains the eight subunits of the TRiC/CCT chaperonin complex. Chaperonins are a ... qRT-PCR analysis of two endogenous HSR genes, hsp-16.2 and C12C8.1 (hsp-70), reveals that HSR induction by cct-1 knockdown is ...
http://www.g3journal.org/content/7/3/1011.full
*  Michael Levitt | Stanford Medicine Profiles
The eukaryotic group II chaperonin TRiC/CCT is a 16-subunit complex with eight distinct but similar subunits arranged in two ... Chaperonins are large ATP-driven molecular machines that mediate cellular protein folding. Group II chaperonins use their " ... Cryo-EM Structure of a Group II Chaperonin in the Prehydrolysis ATP-Bound State Leading to Lid Closure STRUCTURE Zhang, J., Ma ... Mechanism of folding chamber closure in a group II chaperonin NATURE Zhang, J., Baker, M. L., Schroeder, G. F., Douglas, N. R ...
https://med.stanford.edu/profiles/michael-levitt?tab=publications
*  Thermophilic Protein Folding Systems | Springer for Research & Development
Characterization of archeal group II chaperonin-ADP-metal fluoride complexes: ımplications that group II chaperonins operate as ... Yoshida T, Ideno A, Suzuki R, Yohda M, Maruyama T (2002a) Two kinds of archaeal group II chaperonin subunits with different ... Coexistence of group I and group II chaperonins in the archaeon Methanosarcina mazei. J Biol Chem 278(35):33256-33267PubMed ... Klumpp M, Baumeister W (1998) The thermosome: archetype of group II chaperonins. FEBS Lett 430(1-2):73-77PubMedCrossRefGoogle ...
https://rd.springer.com/referenceworkentry/10.1007/978-4-431-53898-1_27
*  Frontiers | Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic...
... a chaperonin (tentatively designated Group III chaperonin) very similar to that occurring in all archaea, i.e., the thermosome ... a chaperonin (tentatively designated Group III chaperonin) very similar to that occurring in all archaea, i.e., the thermosome ... in their cytoplasm and some have also a chaperonin of Group I (GroEL; Cpn60; Hsp60). Conversely, all bacteria have GroEL, some ... in their cytoplasm and some have also a chaperonin of Group I (GroEL; Cpn60; Hsp60). Conversely, all bacteria have GroEL, some ...
https://www.frontiersin.org/articles/10.3389/fmolb.2016.00084/full
*  Wah Chiu's Profile | Stanford Profiles
During evolution, two strategies to close the chaperonin chamber have emerged. Archaeal and eukaryotic group II chaperonins ... The eukaryotic group II chaperonin TRiC/CCT is a 16-subunit complex with eight distinct but similar subunits arranged in two ... Chaperonins are large ATP-driven molecular machines that mediate cellular protein folding. Group II chaperonins use their " ... Here, we describe the fate of the substrate during the nucleotide cycle of group II chaperonins. The chaperonin substrate- ...
https://profiles.stanford.edu/wah-chiu?tab=bio
*  KAKEN - Research Projects | The Single Molecular Design and Systemic Assembly of Protein Function (KAKENHI-PROJECT-14002008)
Journal Article] Kinetics and binding sites for interaction of prefoldin with group II chaperonin : contiguous non-native ... Journal Article] Localization of Prefoldin Interaction Sites in the Hyperthermophilic Group II Chaperonin and Correlations ... Journal Article] Localization of Prefoldin Interaction Sites in the Hyperthermophilic Group II Chaperonin and Correlations ... Journal Article] Mechanochemical coupling of two substeps in a single myosin V motor.2004. *. Author(s). Uemura, S., Higuchi, H ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14002008/
*  Protein Misfolding and Aggregation in Cataract Disease and Prospects for Prevention
The group II chaperonin Mm-Cpn binds and refolds human gammaD crystallin. Protein Sci. 2011;20:30-41. [PubMed] ... the lens cortex and epithelium contain ATP-dependent chaperones including the group II chaperonin CCT. CCT is required for the ... Two-dimensional IR spectroscopy and segmental 13C labeling reveals the domain structure of human gammaD-crystallin amyloid ... For γ- and βcrystallins, which all have two homologous domains, such an interaction could propagate into a large polymeric ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3621977/?lang=en-ca
*  Yeast ampicillin resistance / Bactrim oral suspension cost
Mechanism of action of group II chaperonins [Elektronische. . (useful for providing sugars fermentable by yeast and retarding. ... There are two tests en sjelden gang infeksjoner immunoglobulin M antibody to. How long does a yeast infection last after taking ... A bacterial two-hybrid genome fragment library for. yeast 288 yeast Gateway destination vectors are available. pACTII RfB LEU2 ... All vectors in the CheckMate™ Mammalian Two-Hybrid System confer ampicillin resistance and are compatible with E. coli. ...
http://oyun-oyna.tk/daha/yeast-ampicillin-resistance-zo.php
*  Methanobrevibacter oralis - Wikipedia
"Antigenic group II chaperonin inMethanobrevibacter oralismay cross-react with human chaperonin CCT". Molecular Oral ... "Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT". Pathogens and Disease ... 25 (2): 112-122. doi:10.1111/j.2041-1014.2009.00548.x. ISSN 2041-1006. Khelaifia, S.; Garibal, M.; Robert, C.; Raoult, D.; ... 2 (1): e00073-14-e00073-14. doi:10.1128/genomeA.00073-14. ISSN 2169-8287. LPSN Methanobrevibacter oralis at the Encyclopedia of ...
https://en.wikipedia.org/wiki/Methanobrevibacter_oralis
*  Browse by Author/Supervisor - eTheses Repository
Shah, Riddhi (2014) Functional analysis of Group 2 chaperonins from archaeal species in E. coli. Ph.D. thesis, University of ... Rao, Tara (2010) Analysis of the multiple chaperonins of Mycobacterium smegmatis. Ph.D. thesis, University of Birmingham. ... Pathak, Prachi P. (2014) Project 1: Characterization of EvgAS - two component signal transduction system in Escherichia coli ... Bell, Lawrence (2015) Project 1 - Inhibition of the oxireductase enzyme dpre1 of mycobacterium tuberculosis by two small ...
http://etheses.bham.ac.uk/view/people/Lund=3APeter_A=2E=3A=3A.html
*  Items where Division is "Colleges (2008 onwards) | College of Life & Environmental Sciences" - eTheses Repository
Garner, Lee Ian (2011) Structural and molecular studies of group II leukocyte immunoglobulin-like receptors. Ph.D. thesis, ... Rao, Tara (2010) Analysis of the multiple chaperonins of Mycobacterium smegmatis. Ph.D. thesis, University of Birmingham. ... Lynch, Maeve Ann (2014) Exploring the understanding and use of 'case busts' within two assertive outreach teams. M.Res. thesis ... Shah, Riddhi (2014) Functional analysis of Group 2 chaperonins from archaeal species in E. coli. Ph.D. thesis, University of ...
http://etheses.bham.ac.uk/view/divisions/10col=5Flife.default.html
*  Past Events | Page 36 | Department of Biology
PhD Dissertation Defense - Tom Lopez, "Assembly and Allostery in Group II Chaperonins" ...
https://biology.stanford.edu/events/past-events?mini=2018-04&page=35