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*  Disruption of Growth Factor Receptor-Binding Protein 10 in the Pancreas Enhances β-Cell Proliferation and Protects Mice From...
Grb10: more than a simple adaptor protein. Front Biosci 2004;9:387-403pmid:14766376. ... Growth factor receptor-binding protein 10 (Grb10) is a pleckstrin homology and Src homology 2 (SH2) domain-containing protein ... Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains. J ... 5F). Because Grb10 is highly expressed in pancreas (11) and islets (Fig. 1C and D), and this protein negatively regulates ...
http://diabetes.diabetesjournals.org/content/61/12/3189.full
*  GRB2-Related Adaptor Protein (GRAP) protein (Myc-DYKDDDDK Tag)</span...
Protein (Myc-DYKDDDDK Tag). Species: Human. Source: HEK-293 Cells. Order product ABIN2722222. ... GRB2-Associated Binding Protein 2 Proteins * GRB10 Interacting GYF Protein 2 Proteins ... GRB2-Related Adaptor Protein (GRAP) protein (Myc-DYKDDDDK Tag) GRB2-Related Adaptor Protein (GRAP) protein (Myc-DYKDDDDK Tag). ... Protein Name GRB2-Related Adaptor Protein (GRAP) show synonyms for this antigen * 8430435N19Rik ...
http://www.antibodies-online.com/protein/2722222/GRB2-Related+Adaptor+Protein+GRAP+protein+Myc-DYKDDDDK+Tag/
*  A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10 - IGMM
GRB10 Adaptor Protein/genetics/metabolism; Brain/cytology/embryology/physiology; Cell Differentiation; Chromatin/genetics/* ... As a model to address this question, we studied Grb10, a gene that displays brain-specific expression from the paternal ... A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10. Sanz, L. A.; Chamberlain, S.; Sabourin, ... Our data indicate that bivalent chromatin, in combination with neuronal factors, controls the paternal expression of Grb10 in ...
http://www.igmm.cnrs.fr/publication/a-mono-allelic-bivalent-chromatin-domain-controls-tissue-specific-imprinting-at-grb10/
*  PAF468Hu01 | 生长因子受体结合蛋白10(Grb10)多克隆抗体 | Homo sapiens (Human,人) USCN(武
Grb10), 生长因子受体结合蛋白10(Grb10)多克隆抗体, GRB-IR; IRBP; MEG1; RSS; GRB10 adapter protein; Insulin receptor-binding protein Grb-IR , 仅供体 ... Polyclonal Antibody to Growth Factor Receptor Bound Protein 10 ( ... Grb10). GRB-IR; IRBP; MEG1; RSS; GRB10 adapter protein; Insulin ... Protein-A/G纯化柱. 细胞和组织染色液. 抗体阳性对照品. 组织/切片定制服务. 磷酸化抗体定制服务. 免疫组织化学(IHC)实验服务. 免疫细胞
http://www.uscnk.cn/uscn/Antibody-to-Growth-Factor-Receptor-Bound-Protein-10-Grb10-16585.htm
*  MAP2K1 - Wikipedia
Nantel, A; Mohammad-Ali K; Sherk J; Posner B I; Thomas D Y (Apr 1998). "Interaction of the Grb10 adapter protein with the Raf1 ... protein N-terminus binding. • kinase activity. • protein C-terminus binding. • ATP binding. • transferase activity. • protein ... protein tyrosine kinase activity. • nucleotide binding. • MAP kinase kinase activity. • protein kinase activity. • protein ... MAP2K1 has been shown to interact with C-Raf,[9] Phosphatidylethanolamine binding protein 1,[9] MAP2K1IP1,[10][11] GRB10,[12] ...
https://en.wikipedia.org/wiki/MAP2K1
*  C-Raf - Wikipedia
Nantel A, Mohammad-Ali K, Sherk J, Posner BI, Thomas DY (April 1998). "Interaction of the Grb10 adapter protein with the Raf1 ... 14-3-3 proteins also contribute to the autoinhibition. As 14-3-3 proteins are all known to form constitutive dimers, their ... Raf kinases A-Raf kinase B-Raf kinase KSR1 protein KSR2 protein GRCm38: Ensembl release 89: ENSMUSG00000000441 - Ensembl, May ... Yuryev A, Wennogle LP (February 2003). "Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid ...
https://en.wikipedia.org/wiki/C-Raf
*  Spiral: A Central Role for GRB10 in Regulation of Islet Function in Man
GRB10 Adaptor Protein. Genome-Wide Association Study. Glucose. Humans. Insulin. Insulin Resistance. Islets of Langerhans. Male ... GRB10 Adaptor Protein. Genome-Wide Association Study. Science & Technology. Life Sciences & Biomedicine. Genetics & Heredity. ... A Central Role for GRB10 in Regulation of Islet Function in Man. File. Description. Size. Format. ... A central role for GRB10 in regulation of islet function in man.pdf. Published version. 2.13 MB. Adobe PDF. Download. ...
https://spiral.imperial.ac.uk:8443/handle/10044/1/28744
*  Adhami VM[au] - PubMed - NCBI
Pro-proliferative function of adaptor protein GRB10 in prostate carcinoma.. Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Adhami+VM%5Bau%5D&dispmax=50
*  GRB10 - Wikipedia
"The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10". J. Biol. Chem. 270 (37): ... "The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10". J. Biol. Chem. 270 (37): ... Bai, R Y; Jahn T; Schrem S; Munzert G; Weidner K M; Wang J Y; Duyster J (Aug 1998). "The SH2-containing adapter protein GRB10 ... Nantel, A; Mohammad-Ali K; Sherk J; Posner B I; Thomas D Y (Apr 1998). "Interaction of the Grb10 adapter protein with the Raf1 ...
https://en.wikipedia.org/wiki/GRB10
*  Direct interaction between Kit and the interleukin-7 receptor | Blood Journal
Role for the adaptor protein Grb10 in the activation of Akt. Mol Cell Biol 2002;22:979-991. ... In addition to direct protein-protein interactions, it is likely that a specific membrane environment is also necessary to ... antibody-protein complexes were collected with 30 μL protein A-Sepharose. In an immunoprecipitation experiment, 2 μg of ... STAT protein recruitment and activation in c-Kit deletion mutants. J Biol Chem 1999;274:16965-16972. ...
http://www.bloodjournal.org/content/110/6/1840?sso-checked=true
*  CD117 - Википедија, слободна енциклопедија
Jahn T, Seipel P, Urschel S, Peschel C, Duyster J (2002). „Role for the adaptor protein Grb10 in the activation of Akt". Mol. ... Feng GS, Ouyang YB, Hu DP, Shi ZQ, Gentz R, Ni J (1996). „Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine ... Gueller S, Gery S, Nowak V, Liu L, Serve H, Koeffler HP (2008). „Adaptor protein Lnk associates with Tyr(568) in c-Kit". ... Wollberg P, Lennartsson J, Gottfridsson E, Yoshimura A, Rönnstrand L (2003). „The adapter protein APS associates with the ...
https://sr.wikipedia.org/wiki/CD117
*  RET proto-oncogene - Wikipedia
"The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10". J. Biol. Chem. 270 (37): ... protein kinase activity. • kinase activity. • protein binding. • protein tyrosine kinase activity. • ATP binding. • Ras guanyl- ... membrane protein proteolysis. • phosphorylation. • transmembrane receptor protein tyrosine kinase signaling pathway. • positive ... "The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins". Oncogene. 9 (6): 1661-8. PMID ...
https://en.wikipedia.org/wiki/RET_proto-oncogene
*  GRB10 | SpringerLink
Grb-10; GRB-IR; IRBP; MEG1; RSS The Src Homology 2 (SH2) domain-containing adaptor proteins are a class of signal transducers ... Kazi JU, Rönnstrand L. FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell ... Jahn T, Seipel P, Urschel S, Peschel C, Duyster J. Role for the adaptor protein Grb10 in the activation of Akt. Mol Cell Biol. ... The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse ...
https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-67199-4_101665
*  Stanley S. Schrem, MD | NYU Langone Health
The SH2-containing adapter protein GRB10 interacts with BCR-ABL. Bai RY; Jahn T; Schrem S; Munzert G; Weidner KM; Wang JY; ...
https://nyulangone.org/doctors/1376612242/stanley-s-schrem
*  Frontiers in Bioscience: A virtual library of medicine
Grb10: more than a simple adaptor protein. Mei A. Lim, Heimo Riedel, Feng Liu. [Frontiers In Bioscience, Landmark, 9, 387 - 403 ... Grb10 exceeding the boundaries of a common signaling adapter. Heimo Riedel. [Frontiers In Bioscience, Landmark, 9, 603 - 618, ... Computational protein chemistry of p53 and p53 peptides. Paul W. Brandt-Rauf, Ramon V. Rosal, Robert L. Fine, Matthew R. Pincus ... The protein folding problem: global optimization of force fields. H. A. Scheraga, A. Liwo, S. Oldziej, C. Czaplewski, J. ...
https://www.bioscience.org/landmark/9l/2004
*  Adapter protein. Causes, symptoms, treatment Adapter protein
Treatment Adapter protein. Symptoms and causes Adapter protein Prophylaxis Adapter protein ... The adapter protein, Grb10, is a positive regulator of .... Original Paper: The adapter protein, Grb10, is a positive regulator ... Adapter protein». *. The Transmembrane Adapter Protein SIT Regulates Thymic .... The Transmembrane Adapter Protein SIT ... Adapter protein definition - Medical Dictionary definitions .... Adapter protein: A protein acts as a connecting molecule. An ...
http://drugster.info/medic/term/adapter-protein/
*  Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function | The EMBO Journal
For example, the IGF‐1R indirectly interacts with Nedd4‐1 via its adapter protein Grb10 (Vecchione et al, 2003). However, the ... Plant PJ, Yeger H, Staub O, Howard P, Rotin D (1997) The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+‐ ... Kamynina E, Debonneville C, Bens M, Vandewalle A, Staub O (2001) A novel mouse Nedd4 protein suppresses the activity of the ... IP of endogenous proteins, 1.5 mg proteins from lysed embryonic neural stem cells (grown in the presence of FGF2) were ...
http://emboj.embopress.org/content/30/16/3259?ijkey=d91ee73298f5341a75a7ca73b4c5c1ebcdab2b9b&keytype2=tf_ipsecsha
*  The RET Protooncogene | SpringerLink
The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10. J Biol Chem 270:21461-21463 ... Marsee DK, Venkateswaran A, Tao H et al (2004) Inhibition of heat shock protein 90, a novel RET/PTC1-associated protein, ... Lucero HA, Robbins PW (2004) Lipid rafts-protein association and the regulation of protein activity. Arch Biochem Biophys 426: ... Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7. J Biol Chem ...
https://link.springer.com/chapter/10.1007/978-1-4419-0857-5_17
*  Frontiers | Akt and mTOR in B Cell Activation and Differentiation | Immunology
... proteins and mTORC1-dependent phosphorylation of the adaptor protein Grb10 (Yea and Fruman, 2011; Laplante and Sabatini, 2012 ... and the eIF4E binding proteins (4EBPs; Figure 2; Laplante and Sabatini, 2012). S6Ks promote protein and lipid synthesis and ... Proteins recruited to the membrane through binding to PI3K lipid products are generally termed PI3K effectors (Fruman, 2004; ... The mTOR kinase is encoded by a single gene in mammals but is the active enzyme in two distinct multi-protein complexes called ...
https://www.frontiersin.org/articles/10.3389/fimmu.2012.00228/full
*  anti-GRB10 antibody | GeneTex
... growth factor receptor-bound protein 10) for IHC-P, WB. Anti-GRB10 pAb (GTX125980) is tested in Human samples. 100% Ab- ... GRB10 adaptor protein antibody, growth factor receptor-bound protein 10 antibody, GRB10 adapter protein antibody. ... growth factor receptor-bound protein 10. Background. The product of this gene belongs to a small family of adapter proteins ... GRB10. 2887. A7VJ95, Q13322. 601523. NP_001337743. 67.25. Homo sapiens. GRB10. 2887. A7VJ95, Q13322. 601523. NP_001337745. 66.5 ...
http://www.genetex.com/GRB10-antibody-GTX125980.html
*  CD117 - wikidoc
"Role for the adaptor protein Grb10 in the activation of Akt". Mol. Cell. Biol. 22 (4): 979-91. PMC 134632 Freely accessible. ... Feng GS, Ouyang YB, Hu DP, Shi ZQ, Gentz R, Ni J (May 1996). "Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine ... Gueller S, Gery S, Nowak V, Liu L, Serve H, Koeffler HP (October 2008). "Adaptor protein Lnk associates with Tyr(568) in c-Kit ... "The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit". Biochem. J. 370 (Pt 3 ...
http://es.wikidoc.org/index.php/CD117
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Growth receptor binding protein 10 (Grb10) is an adaptor protein that interacts with the insulin receptor and insulin-like ... Protein expression was detected by western blot analysis. We found that Grb10 was expressed in both human and rat pancreas. ... However, the roles of Grb10 in ?-cells remain unknown. The aim of the present study was to explore the effect of Grb10 on ?- ... Based on predicted protein features showing a shared conserved domain with the collagen-binding protein Cna of Staphylococcus ...
https://www.jove.com/visualize?author=Junxi+Wu
*  Signal Transducing Adaptor Proteins Summary Report | CureHunter
Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing ... A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, ... Proto-Oncogene Proteins c-crk: 6. *B cell linker protein: 4. *GRB10 Adaptor Protein: 4 ... Amino Acids, Peptides, and Proteins*Proteins: 90489*Carrier Proteins: 11456*Signal Transducing Adaptor Proteins*Caveolin 1: ...
http://www.curehunter.com/public/keywordSummaryD048868-Signal-Transducing-Adaptor-Proteins.do
*  Recombinant Human GRB10 cell lysate GRB10-751HCL - Creative BioMart
Recombinant Human GRB10 cell lysate can be used for research. ... Purified Recombinant Human GRB10 cell lysate from Creative ... GRB10. Synonyms:. GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally ... GRB10-751HCL. Description:. The product of this gene belongs to a small family of adapter proteins that are known to interact ... Recombinant Human GRB10 cell lysate. Download Datasheet See All GRB10 Products. Bring this labeled protein directly to your ...
https://www.creativebiomart.net/description_411593_318.htm
*  GRB1 | definition of GRB1 by Medical dictionary
GRB10. *GRB10. *GRB10 adapter protein. *Grb10 adaptor protein. *GRB14. *GRB14 adapter protein ... PIK3R1 binds to activated (phosphorylated) protein-Tyr kinases through its SH2 domain and acts as an adapter, mediating the ...
http://medical-dictionary.thefreedictionary.com/GRB1