Edaravone alleviates Alzheimer's disease-type pathologies and cognitive deficits | PNAS
2008) Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to ... 2000) Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J ... Consistently, Edaravone can increase the activation pS9-GSK3β which self-inactivates GSK3β kinase activities (38). These ... event of Aβ toxicity that is caused by Tau hyperphosphorylation triggered by Aβ-induced activation of several kinases such as ...