Gut microbiota alteration and modulation in hepatitis B virus-related fibrosis and complications: Molecular mechanisms and...
Rifaximin beneficially altered intestinal ammonia generation by regulating intestinal glutaminase expression independent of gut ...
Challenge Awards-Class of 2017 | Prostate Cancer Foundation
CB-839 is a novel, orally bioavailable inhibitor of glutaminase, a key enzyme in the metabolism of glutamine. Cancer cells ... Project Title: Glutamine Metabolism in Prostate Cancer: Preclinical and Clinical Evaluation of Dual Inhibition of Glutaminase ... in prostate cancer for treatment of mCRPC and identify biomarkers that predict response to the combination of glutaminase plus ...
Nutrients | Free Full-Text | Potassium Metabolism and Management in Patients with CKD
Phosphate-dependent glutaminase (PDG) is the key enzyme for NH3 production, and its activity is increased by acidosis and ...
Pathobiology of pulmonary arterial hypertension: understanding the roads less travelled | European Respiratory Society
Forschung & Wissenschaft - Ostschweizer Kinderspital | Das kompletteste Angebot der Ostschweiz
WikiGenes - Carbamoyl - aminomethanone
Bing ZHAO | MD PhD | Menzies Research Institute, Hobart | Research profile
We have previously shown that inhibition of glutaminase 1, which catalyzes the rate-limiting step of glutamine catabolism, ...
Volume 77, Number 1, 2020 | Journal of Alzheimer's Disease
Conclusion: These results suggest that the attenuation of upregulated hippocampal glutaminase by JHU-083 represents a new ... Glutamine Antagonist JHU-083 Normalizes Aberrant Hippocampal Glutaminase Activity and Improves Cognition in APOE4 Mice. ... isolated from hippocampi of adult APOE4 knock-in mice to evaluate the effect of JHU-083 treatment on LPS-induced glutaminase ( ...
Portosystemic Encephalopathy: Background, Pathophysiology, Etiology
Glutaminase activity and generation of ammonia in stored cellular blood products (especially platelets) may conceivably lead to ...
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy | eLife
Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells
Thesis Yaiza Maria Arenas Ortiz - Centro Investigación Príncipe Felipe
IUCr) Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B
Cellular Metabolism DOJINDO LABORATORIES
S. Zhao, et al, "BAG3 promotes autophagy and glutaminolysis via stabilizing glutaminase", Cell Death & Disease, 2019, 284(10). ... Promotion of autophagy and glutaminolysis via stabilization of glutaminase by BAG3. BAG3 is a protein involved in the ... In cells overexpressing BAG3, glutaminase (GLS) succinylation is promoted, which prevents ubiquitination and subsequent ...
Regulatory T Cells Control Effector T Cell Inflammation in Human Prediabetes | Diabetes | American Diabetes Association
Frontiers | Pro-tumorigenic role of type 2 diabetes-induced cellular senescence in colorectal cancer
Search Results For Health And Wellness: Inesinal Results found: 1
The pathways for glutamine metabolism can include reactions catalysed by aspartate aminotransferase, glutaminase, succinate ...
The Use of Ketamine in the Acute Management of Depression
The cycle is completed with the transport of glutamine to presynaptic neurons, where it is deaminated by glutaminase to reform ...
Ketogenic HMGCS2 Is a c-Myc Target Gene Expressed in Differentiated Cells of Human Colonic Epithelium and Down-Regulated in...
BiGG Reaction GLUNpp in iEC042 1314
Metabolomics Workbench : NIH Data Repository
Latest Bio-IT News | Bio-IT World
IIT-H researchers identify Antarctic fungi to treat childhood cancer - India4u - News, , Entertainment , Bollywood, Travel,...
The absence of glutaminase and urease would prevent the serious side effects currently seen with the use of bacteria-derived L- ... However, the newly isolated Antarctic fungi was found to have L-Asparaginase free of glutaminase and urease.. The potency of ... However, L-Asparaginase is always associated with two other enzymes -- glutaminase and urease -- which cause adverse side ...
Table of Contents - September 01, 2005, 25 (5) | Anticancer Research
Clinical impact of a gluten-free diet on health-related quality of life in seven fibromyalgia syndrome patients with associated...
... drug prescriptions and tissue-Trans-Glutaminase (tTG) serum levels. At baseline, all patients had poor Quality of Life and VAS ... Anti-IgA tissue Trans-Glutaminase subtype 2 (tTG) antibodies were measured with an ELISA kit from Phadia Diagnostics (Upsala, ... drug prescriptions and tissue-Trans-Glutaminase (tTG) serum levels. ...