Protein Glutaminase (enzyme processing aid)Protein Glutaminase (enzyme processing aid)

FSANZ Internet Consumer Additives and processing aids Protein Glutaminase (enzyme processing aid) ... Protein Glutaminase improves a proteins solubility in water, which provides superior functionality in terms of foaming, ... The technological purpose of Protein Glutaminase is to alter the structure of protein in foods, effectively changing from a " ... Read the assessment report and submissions: A1136 - Protein Glutaminase as a Processing Aid (Enzyme) ...
more infohttp://www.foodstandards.gov.au/consumer/additives/Pages/Protein-Glutaminase-

GLS glutaminase [Homo sapiens (human)] - Gene - NCBIGLS glutaminase [Homo sapiens (human)] - Gene - NCBI

glutaminase kidney isoform, mitochondrial. Names. K-glutaminase. L-glutamine amidohydrolase. glutaminase C. glutaminase, ... Glutaminase; Glutaminase. pfam13637. Location:587 → 639. Ank_4; Ankyrin repeats (many copies). sd00045. Location:557 → 583. ANK ... Glutaminase; Glutaminase. pfam12796. Location:557 → 597. Ank_2; Ankyrin repeats (3 copies). ... glutaminaseprovided by HGNC. Primary source. HGNC:HGNC:4331 See related. Ensembl:ENSG00000115419 MIM:138280 Gene type. protein ...
more infohttps://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=DetailsSearch&Term=2744

GLS (Glutaminase)GLS (Glutaminase)

Glutaminase), Authors: José A. Campos-Sandoval, Mercedes Martin-Rufián, Javier Márquez. Published in: Atlas Genet Cytogenet ... GLS gene encodes two isoforms, known as kidney-type glutaminase (KGA) and glutaminase C (GAC). Upregulation of GLS is a common ... suckling behavior regulation of respiratory gaseous exchange by neurological system process glutaminase activity glutaminase ... suckling behavior regulation of respiratory gaseous exchange by neurological system process glutaminase activity glutaminase ...
more infohttp://atlasgeneticsoncology.org/Genes/GLSID45600ch2q32.html

glutaminase (human)glutaminase (human)

The lollipop plot above illustrates recurrent (observed in 3 or more out of 4440 TCGA tumor samples from 15 cancer types) and therefore potentially oncogenic missense mutations (click on Show Cancer Mutations). The bar plot below shows the proportion of tumor samples that have any kind of altering mutation(s) in the given protein. ...
more infohttps://www.phosphosite.org/proteinAction.action?id=7081&showAllSites=true

glutaminase: Topics by WorldWideScience.orgglutaminase: Topics by WorldWideScience.org

Both glutaminase siRNA and glutaminase inhibition have been shown to be effective in in vitro models of cancer and HAD, ... Both glutaminase siRNA and glutaminase inhibition have been shown to be effective in in vitro models of cancer and HAD, ... Both glutaminase siRNA and glutaminase inhibition have been shown to be effective in in vitro models of cancer and HAD, ... The extracellular glutaminases activity was found to be much higher than that of cell-bound glutaminase. The highest specific ...
more infohttps://worldwidescience.org/topicpages/g/glutaminase.html

Product Overview anti-Glutaminase AntibodiesProduct Overview anti-Glutaminase Antibodies

Order monoclonal and polyclonal Glutaminase antibodies for many applications. Selected quality suppliers for anti-Glutaminase ... glutaminase kidney isoform, mitochondrial , glutaminase C , glutaminase , phosphate-activated glutaminase , glutaminase, ... L-glutaminase , glutaminase liver isoform, mitochondrial , liver mitochondrial glutaminase , Glutaminase ... Glutaminase (GLS) Antigen Profile Antigen Summary This gene encodes the K-type mitochondrial glutaminase. The encoded protein ...
more infohttp://www.antibodies-online.com/feeding-behaviour-pathway-91/glutaminase-antibody-4523/

Clinical Trials Using Glutaminase Inhibitor CB-839 - National Cancer InstituteClinical Trials Using Glutaminase Inhibitor CB-839 - National Cancer Institute

Glutaminase inhibitor CB-839 and azacitidine may stop the growth of tumor cells by blocking some of the enzymes needed for cell ... Glutaminase inhibitor CB-839 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. ... Glutaminase Inhibitor CB-839 and Capecitabine in Treating Patients with Advanced Solid Tumors or Colorectal Cancer This phase I ... Glutaminase inhibitor CB-839 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. ...
more infohttps://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/glutaminase-inhibitor-cb-839

Tissue Trans-glutaminase-directed IgA EIA Kit from Alpco DiagnosticsTissue Trans-glutaminase-directed IgA EIA Kit from Alpco Diagnostics

Anti-Tissue Trans-glutaminase (IgA) EIA 10 l,biological,biology supply,biology supplies,biology product ... Tissue Trans-glutaminase-directed IgA EIA Kit from Alpco Diagnostics, ... Anti-Tissue Trans-glutaminase (IgA) EIASample Size: 10 l. Info. Alpco Diagnostics. American Laboratory Products Company PO Box ...
more infohttp://www.bio-medicine.org/biology-products/Tissue-Trans-glutaminase-directed-IgA-EIA-Kit-from-Alpco-Diagnostics-933-1/

Glutaminase - WikipediaGlutaminase - Wikipedia

Glutaminase (EC 3.5.1.2, glutaminase I, L-glutaminase, glutamine aminohydrolase) is an amidohydrolase enzyme that generates ... Glutaminase has tissue-specific isoenzymes. Glutaminase has an important role in glial cells. Glutaminase catalyzes the ... GLS1 encodes 2 types of kidney-type glutaminase with a high activity and low Km. GLS2 encodes 2 forms of liver-type glutaminase ... Glutaminase at the US National Library of Medicine Medical Subject Headings (MeSH) Research information on glutaminase ( ...
more infohttps://en.wikipedia.org/wiki/Glutaminase

GLS2 / Glutaminase 2 - LSBioGLS2 / Glutaminase 2 - LSBio

glutaminase 2 (liver, mitochondrial). Synonyms:. GLS2, GA, Glutaminase 2, Glutaminase I, Glutaminase GA, L-glutaminase, HLGA, L ... GLS2 / Glutaminase 2. glutaminase 2 (liver, mitochondrial). Plays an important role in the regulation of glutamine catabolism. ... Rabbit Polyclonal (IgG) to Human GLS2 / Glutaminase 2 Reactivity:. Zebrafish, Mouse, Dog, Pig, Horse, Bat, Rat, Gibbon, Human, ... Rabbit Polyclonal (IgG) to Human GLS2 / Glutaminase 2 Reactivity:. Zebrafish, Mouse, Dog, Pig, Horse, Bat, Rat, Gibbon, Human, ...
more infohttps://www.lsbio.com/targets/gls2-glutaminase-2/g7066

polyethylene glycol-glutaminase-asparaginase - Semantic Scholarpolyethylene glycol-glutaminase-asparaginase - Semantic Scholar

Acinetobacter glutaminase-asparaginase (AGA) possesses both L-glutaminase and L-asparaginase activities, capable of hydrolyzing ... polyethylene glycol-glutaminase-asparaginase. Known as: PEG-Glutaminase-Asparaginase, PEG-L-glutaminase-L-asparaginase, ... Glutaminase-Asparaginase (More). A dual function enzyme derived from bacterial Acinetobacter glutaminasificans used as an ... L-Asparaginase and L-glutaminase activities were detected in many microorganisms and the distribution of these activities was… ...
more infohttps://www.semanticscholar.org/topic/polyethylene-glycol-glutaminase-asparaginase/14446

D-glutaminase - WikipediaD-glutaminase - Wikipedia

In enzymology, a D-glutaminase (EC 3.5.1.35) is an enzyme that catalyzes the chemical reaction D-glutamine + H2O ⇌ {\ ...
more infohttps://en.wikipedia.org/wiki/D-glutaminase

Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation.  - PubMed - NCBISynaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation. - PubMed - NCBI

Glutaminase-deficient mice (GLS1 hets), with reduced glutamate recycling, have a focal reduction in hippocampal activity, ... Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation.. Gaisler-Salomon I1, ... The maturity-onset reduction in NR1 gene expression and in contextual learning supports the premise that glutaminase inhibition ... Synaptic Underpinnings of Altered Hippocampal Function in Glutaminase Deficient Mice During Maturation ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/22431402

cheB - Protein-glutamate methylesterase/protein-glutamine glutaminase - Maricaulis maris (strain MCS10) - cheB gene & proteincheB - Protein-glutamate methylesterase/protein-glutamine glutaminase - Maricaulis maris (strain MCS10) - cheB gene & protein

Protein-glutamate methylesterase/protein-glutamine glutaminaseAdd BLAST. 401. Amino acid modifications. Feature key. Position(s ... Protein-glutamate methylesterase/protein-glutamine glutaminaseUniRule annotation. Manual assertion according to rulesi ... sp,Q0ARY3,CHEB_MARMM Protein-glutamate methylesterase/protein-glutamine glutaminase OS=Maricaulis maris (strain MCS10) OX= ...
more infohttps://www.uniprot.org/uniprot/Q0ARY3

Some properties of the glutaminase of Clostridium welchii | Biochemical JournalSome properties of the glutaminase of Clostridium welchii | Biochemical Journal

Some properties of the glutaminase of Clostridium welchii. D. E. Hughes, D. H. Williamson ... Some properties of the glutaminase of Clostridium welchii Message Subject (Your Name) has forwarded a page to you from ...
more infohttp://www.biochemj.org/content/51/1/45

Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | Sigma-AldrichInhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | Sigma-Aldrich

Glutamine is converted to glutamate by glutaminase and further metabolized to α-KG. Therefore, we inhibited glutaminase with ... Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.. [Meghan J Seltzer, Bryson D Bennett, ... BPTES inhibited glutaminase activity, lowered glutamate and α-KG levels, and increased glycolytic intermediates while leaving ... The ability to selectively slow growth in cells with IDH1 mutations by inhibiting glutaminase suggests a unique reprogramming ...
more infohttps://www.sigmaaldrich.com/catalog/papers/21045145

7,000 signatures on Glutaminase petition presented to FSANZ - Food Intolerance Network7,000 signatures on Glutaminase petition presented to FSANZ - Food Intolerance Network

The petition has with it a formal response on our reasons why Protein Glutaminase should not be approved as a ... 2. Protein Glutaminase is an Additive and not a Processing Aid as defined by the Australia New Zealand Food Standards Code and ... 1. declaring Protein Glutaminase as a Processing Aid is in breach of Object (c) of the Food Standards Australia New Zealand Act ... 3. Protein Glutaminase is a protease as currently listed in the Australia New Zealand Food Standards Code and so is legally ...
more infohttps://www.fedup.com.au/news/blog/7000-signatures-on-glutaminase-petition-presented-to-fsanz

The intramitochondrial location of the glutaminase isoenzymes of pig kidney | Biochemical JournalThe intramitochondrial location of the glutaminase isoenzymes of pig kidney | Biochemical Journal

The intramitochondrial location of the glutaminase isoenzymes of pig kidney. M. Crompton, J. D. Mcgivan, J. B. Chappell ... 1. The glutaminase activity of pig kidney is located almost entirely in the cortex. 2. Pig renal cortex contains two ... The intramitochondrial location of the glutaminase isoenzymes of pig kidney Message Subject (Your Name) has forwarded a page to ... 5. It is concluded that both glutaminase isoenzymes are situated in the intramitochondrial compartment, and that the phosphate- ...
more infohttp://www.biochemj.org/content/132/1/27

Localization and characterization of glutaminase activity in the murine macrophage | Biochemical Society TransactionsLocalization and characterization of glutaminase activity in the murine macrophage | Biochemical Society Transactions

Localization and characterization of glutaminase activity in the murine macrophage. NEWSHOLME PHILIP, RUI CURI, EVA BLOMSTRAND ... Localization and characterization of glutaminase activity in the murine macrophage. NEWSHOLME PHILIP, RUI CURI, EVA BLOMSTRAND ... Localization and characterization of glutaminase activity in the murine macrophage Message Subject (Your Name) has forwarded a ...
more infohttp://www.biochemsoctrans.org/content/15/3/536

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer | Molecular Cancer TherapeuticsAntitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer | Molecular Cancer Therapeutics

TNBC cell lines are sensitive to glutaminase inhibition with CB-839. The elevated levels of glutaminase detected in TNBC ... but not the liver form of glutaminase, encoded by the GLS2 gene (18, 19, 21, 22). CB-839 (Fig. 1A) is a novel glutaminase ... Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer. Matt I. Gross, Susan D. Demo, Jennifer ... Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res 2010;70:8981-7. ...
more infohttp://mct.aacrjournals.org/content/13/4/890?ijkey=21cfb8cb388fa73a010ade061b8c506bfbf454e9&keytype2=tf_ipsecsha

Phosphate-activated glutaminase (PAG) activity staining | Open-iPhosphate-activated glutaminase (PAG) activity staining | Open-i

Phosphate-activated glutaminase (PAG) activity staining in kidney tissue. (A) Stitched overview image of PAG activity in mouse ... fig8-0022155414551177: Phosphate-activated glutaminase (PAG) activity staining in kidney tissue. (A) Stitched overview image of ... fig8-0022155414551177: Phosphate-activated glutaminase (PAG) activity staining in kidney tissue. (A) Stitched overview image of ... Determination of phosphate-activated glutaminase activity and its kinetics in mouse tissues using metabolic mapping ( ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4230542_10.1369_0022155414551177-fig8&req=4

First-in-class glutaminase inhibitor combats anti-PD-1/PD-L1 resistance | CHEST PhysicianFirst-in-class glutaminase inhibitor combats anti-PD-1/PD-L1 resistance | CHEST Physician

Combination treatment with the first-in-class glutaminase inhibitor CB-839 and nivolumab shows promise for overcoming anti-PD-1 ... Key clinical point: Combination treatment with the first-in-class glutaminase inhibitor CB-839 and nivolumab shows promise for ... Combination treatment with the first-in-class glutaminase inhibitor CB-839 and nivolumab is well-tolerated and shows clinical ... First-in-class glutaminase inhibitor combats anti-PD-1/PD-L1 resistance. ...
more infohttps://www.mdedge.com/chestphysician/article/153307/immuno-oncology/first-class-glutaminase-inhibitor-combats-anti-pd-1/pd

Biomolecules | Free Full-Text | Glutaminase Increases in Rat Dorsal Root Ganglion Neurons after Unilateral Adjuvant-Induced...Biomolecules | Free Full-Text | Glutaminase Increases in Rat Dorsal Root Ganglion Neurons after Unilateral Adjuvant-Induced...

Glutaminase (GLS) is an enzyme of the glutamate-glutamine cycle that converts glutamine into glutamate for neurotransmission ... Keywords: glutaminase; glutamate; adjuvant-induced arthritis; complete Freunds adjuvant; dorsal root ganglion glutaminase; ... Glutaminase Increases in Rat Dorsal Root Ganglion Neurons after Unilateral Adjuvant-Induced Hind Paw Inflammation. E. Matthew ... Glutaminase (GLS) is an enzyme of the glutamate-glutamine cycle that converts glutamine into glutamate for neurotransmission ...
more infohttp://www.mdpi.com/2218-273X/6/1/10

Frontiers | The Glutaminase-Dependent System Confers Extreme Acid Resistance to New Species and Atypical Strains of Brucella |...Frontiers | The Glutaminase-Dependent System Confers Extreme Acid Resistance to New Species and Atypical Strains of Brucella |...

The Glutaminase-Dependent System Confers Extreme Acid Resistance to New Species and Atypical Strains of Brucella. Luca Freddi1† ... In Brucella genomes, a putative glutaminase (glsA)-coding gene is located downstream of the gadBC genes. We found that in B. ... More recently the antiporter GadC and the enzyme glutaminase (YbaS in E. coli and Gls3 in L. reuteri) were shown to act in ... Analysis of the genome sequence of B. microti reveals that, unlike E. coli that possesses two glutaminase-encoding genes (ybaS ...
more infohttps://www.frontiersin.org/articles/10.3389/fmicb.2017.02236/full

Structure Cluster 









- 1DJP: CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON...Structure Cluster - 1DJP: CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON...

Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected ... Description: GLUTAMINASE-ASPARAGINASE protein , Length: 330 No structure alignment results are available for 1DJP.A, 1DJP.B ... CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON COVALENTLY BOUND IN THE ACTIVE SITE. ...
more infohttp://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1DJP