What are the stages of stiff person syndrome?What are the stages of stiff person syndrome?

Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive ... Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ... Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. J Neurol Sci. 2000 Apr ... Lernmark A. Glutamic acid decarboxylase--gene to antigen to disease. J Intern Med. 1996 Nov. 240(5):259-77. [Medline]. ...
more infohttps://www.medscape.com/answers/1172135-113977/1829737-overview

Stiff Person Syndrome Workup: Laboratory Studies, Imaging Studies, Other TestsStiff Person Syndrome Workup: Laboratory Studies, Imaging Studies, Other Tests

Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive ... Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ... Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. J Neurol Sci. 2000 Apr ... Butler MH, Solimena M, Dirkx R Jr, Hayday A, De Camilli P. Identification of a dominant epitope of glutamic acid decarboxylase ...
more infohttps://emedicine.medscape.com/article/1172135-workup

OPUS Würzburg | Human Stiff-Person Syndrome IgG Induces Anxious Behavior in RatsOPUS Würzburg | Human Stiff-Person Syndrome IgG Induces Anxious Behavior in Rats

Most patients have high-titer antibodies against glutamate decarboxylase (GAD) 65. The pathogenic role of these autoantibodies ... Most patients have high-titer antibodies against glutamate decarboxylase (GAD) 65. The pathogenic role of these autoantibodies ... Most patients have high-titer antibodies against glutamate decarboxylase (GAD) 65. The pathogenic role of these autoantibodies ... 65-kda isoform; Glutamic-acid decarboxylase anxiety; antibodies; anxiety; autoantibodies; disorder; fear memory; neurons; ...
more infohttps://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/searchtype/authorsearch/author/Thomas+Wultsch/rows/20/start/0/subjectfq/autoantibodies/docId/14050

Glutamate decarboxylase - WikipediaGlutamate decarboxylase - Wikipedia

Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to ... Media related to Glutamate decarboxylase at Wikimedia Commons Genetics, Expression Profiling Support GABA Deficits in ... Kaufman DL, Houser CR, Tobin AJ (1991). "Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have ... Erlander MG, Tillakaratne NJ, Feldblum S, Patel N, Tobin AJ (July 1991). "Two genes encode distinct glutamate decarboxylases". ...
more infohttps://en.wikipedia.org/wiki/Glutamate_decarboxylase

Glutamate decarboxylase - WikipediaGlutamate decarboxylase - Wikipedia

Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to ... Role of glutamate decarboxylase in Citrus[edit]. It is also believed that the control of glutamate decarboxylase has the ... research has shown that glutamate decarboxylase plays a key role in citrate metabolism. With the increase of glutamate ... Ueno H (October 2000). "Enzymatic and structural aspects on glutamate decarboxylase". Journal of Molecular Catalysis B: ...
more infohttps://en.wikipedia.org/wiki/GAD_antibodies

Glutamate decarboxylase - WikipediaGlutamate decarboxylase - Wikipedia

Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to ... Role of glutamate decarboxylase in Citrus[edit]. It is also believed that the control of glutamate decarboxylase has the ... research has shown that glutamate decarboxylase plays a key role in citrate metabolism. With the increase of glutamate ... Ueno H (October 2000). "Enzymatic and structural aspects on glutamate decarboxylase". Journal of Molecular Catalysis B: ...
more infohttps://en.wikipedia.org/wiki/Glutamic_acid_decarboxylase

Glutamate decarboxylase (A0A222QS57) | InterPro | EMBL-EBIGlutamate decarboxylase (A0A222QS57) | InterPro | EMBL-EBI

GO:0004351 glutamate decarboxylase activity GO:0016831 carboxy-lyase activity GO:0030170 pyridoxal phosphate binding ...
more infohttps://www.ebi.ac.uk/interpro/protein/A0A222QS57

Glutamate decarboxylase definition | Drugs.comGlutamate decarboxylase definition | Drugs.com

Definition of glutamate decarboxylase. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and ... glutamate decarboxylase. Definition: a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO2 as well as l-aspartate ... Synonym(s): aspartate 1-decarboxylase. Further information. Always consult your healthcare provider to ensure the information ...
more infohttps://www.drugs.com/dict/glutamate-decarboxylase.html

GAD2 glutamate decarboxylase 2 [Homo sapiens (human)] - Gene - NCBIGAD2 glutamate decarboxylase 2 [Homo sapiens (human)] - Gene - NCBI

glutamate decarboxylase 2. Names. 65 kDa glutamic acid decarboxylase. GAD-65. Glutamate decarboxylase-2 (pancreas). glutamate ... GAD2 glutamate decarboxylase 2 [Homo sapiens] GAD2 glutamate decarboxylase 2 [Homo sapiens]. Gene ID:2572 ... Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain. * NM_001134366.2 → NP_001127838.1 glutamate decarboxylase 2 ... glutamate decarboxylase 2provided by HGNC. Primary source. HGNC:HGNC:4093 See related. Ensembl:ENSG00000136750 MIM:138275 Gene ...
more infohttps://www.ncbi.nlm.nih.gov/gene/2572

Gad1 - Glutamate decarboxylase - Mus musculus (Mouse) - Gad1 gene & proteinGad1 - Glutamate decarboxylase - Mus musculus (Mouse) - Gad1 gene & protein

Glutamate decarboxylaseImported. ,p>Information which has been imported from another database using automatic procedures.,/p> , ... tr,Q548L6,Q548L6_MOUSE Glutamate decarboxylase OS=Mus musculus GN=Gad1 PE=1 SV=1 ... Glutamic acid decarboxylase 1Imported. ,p>Information which has been imported from another database using automatic procedures ... Belongs to the group II decarboxylase family.UniRule annotation. ,p>Information which has been generated by the UniProtKB ...
more infohttp://www.uniprot.org/uniprot/Q548L6

gadA - Glutamate decarboxylase alpha - Shigella flexneri - gadA gene & proteingadA - Glutamate decarboxylase alpha - Shigella flexneri - gadA gene & protein

Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to ... Glutamate decarboxylase alphaAdd BLAST. 466. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... IPR010107 Glutamate_decarboxylase. IPR002129 PyrdxlP-dep_de-COase. IPR015424 PyrdxlP-dep_Trfase. IPR015421 PyrdxlP-dep_Trfase_ ... sp,Q83PR1,DCEA_SHIFL Glutamate decarboxylase alpha OS=Shigella flexneri OX=623 GN=gadA PE=3 SV=2 ...
more infohttps://www.uniprot.org/uniprot/Q83PR1

WikiGenes - GAD2 - glutamate decarboxylase 2 (pancreatic...WikiGenes - GAD2 - glutamate decarboxylase 2 (pancreatic...

Synonyms: 65 kDa glutamic acid decarboxylase, GAD-65, GAD65, Glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform ... Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children? ... Glutamate decarboxylase genes and alcoholism in han taiwanese men. Loh, e.l.-.W., Lane, H.Y., Chen, C.H., Chang, P.S., Ku, L.W ... Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of ...
more infohttps://www.wikigenes.org/e/gene/e/2572.html

Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with...Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with...

Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with ... Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with ... Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with ... Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with ...
more infohttps://www.jneurosci.org/content/3/7/1450

Differential islet cell expression of two glutamate decarboxylases, both autoantigens in diabetes | Biochemical Society...Differential islet cell expression of two glutamate decarboxylases, both autoantigens in diabetes | Biochemical Society...

Differential islet cell expression of two glutamate decarboxylases, both autoantigens in diabetes Birgitte Koch Michelsen ... IDDM, insulin-dependent diabetes mellitus, GAD, glutamate decarboxylase, GABA, γ-aminobutyrate, CNS, central nervous system, ... Differential islet cell expression of two glutamate decarboxylases, both autoantigens in diabetes. Biochem Soc Trans 1 February ...
more infohttps://portlandpress.com/biochemsoctrans/article-abstract/21/1/173/80888/Differential-islet-cell-expression-of-two

The 58-Kilodalton Calmodulin-Binding Glutamate Decarboxylase Is a Ubiquitous Protein in Petunia Organs and Its Expression Is...The 58-Kilodalton Calmodulin-Binding Glutamate Decarboxylase Is a Ubiquitous Protein in Petunia Organs and Its Expression Is...

A cDNA coding for a 58-kD calcium-dependent calmodulin (CaM)-binding glutamate decarboxylase (GAD) previously isolated in our ... The 58-Kilodalton Calmodulin-Binding Glutamate Decarboxylase Is a Ubiquitous Protein in Petunia Organs and Its Expression Is ... The 58-Kilodalton Calmodulin-Binding Glutamate Decarboxylase Is a Ubiquitous Protein in Petunia Organs and Its Expression Is ... The 58-Kilodalton Calmodulin-Binding Glutamate Decarboxylase Is a Ubiquitous Protein in Petunia Organs and Its Expression Is ...
more infohttp://www.plantphysiol.org/content/106/4/1381

Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution,...Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution,...

"Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution, ... Calmodulin binding to glutamate decarboxylase is required for regulation of glutamate and GABA metabolism and normal ... Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution. ... Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and... Zik, Moriyah; Arazi, Tzahi; ...
more infohttps://www.deepdyve.com/lp/springer-journals/two-isoforms-of-glutamate-decarboxylase-in-arabidopsis-are-regulated-syxI0NV2ur?impressionId=5e21d583b25a1&i_medium=docview&i_campaign=references&i_source=references

Anti-Glutamate Decarboxylase 1/2 Antibody  - Rabbit Anti-Rat Polyclonal Antibody WB, IHC-P, IHC-F, IF, E - Buy Now! |AbgentAnti-Glutamate Decarboxylase 1/2 Antibody - Rabbit Anti-Rat Polyclonal Antibody WB, IHC-P, IHC-F, IF, E - Buy Now! |Abgent

Anti-Glutamate Decarboxylase 1/2 Antibody , Rabbit Anti-Rat Polyclonal Antibody validated in WB, IHC-P, IHC-F, IF, E (ABD11280 ... Glutamate decarboxylase 2, 4.1.1.15, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, Gad2, ... home , Products , Primary Antibodies , Neuroscience , Anti-Glutamate Decarboxylase 1/2 Antibody Anti-Glutamate Decarboxylase 1/ ... Rabbit anti-Glutamate Decarboxylase 1/2 antibody recognizes both molecular forms of glutamate decarboxylase, GAD1 (GAD67) and ...
more infohttp://www.abgent.com/products/ABD11280-Anti-Glutamate-Decarboxylase-12-Antibody-

Glutamate decarboxylase 2Glutamate decarboxylase 2

Tyrosine-phosphatase and glutamate-decarboxylase antibodies after simultaneous pancreas kidney transplantation: do they have an ... Data suggest that women with gestational diabetes who develop autoantibodies against GAD2 (glutamate decarboxylase 2) exhibit ... Lower glutamic acid decarboxylase 65-kDa isoform messenger RNA and protein levels in the prefrontal cortex in schizoaffective ... Glutamic acid decarboxylase autoantibody-positivity post-partum is associated with impaired ?-cell function in women with ...
more infohttps://pharos.nih.gov/idg/targets/Q05329

Glutamate Decarboxylase | The Chopra LibraryGlutamate Decarboxylase | The Chopra Library

A recent report suggests that the down-regulation of reelin and glutamic acid decarboxylase (GAD(67)) mRNAs represents 2 of the ... Reelin and glutamic acid decarboxylase 67 (GAD67) mRNAs and protein levels are substantially reduced in postmortem brains of ... DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. ...
more infohttp://isharonline.org/tags/glutamate-decarboxylase

L-Glutamate Decarboxylase (Crude Enzyme)(EC 4.1.1.15) - Creative EnzymesL-Glutamate Decarboxylase (Crude Enzyme)(EC 4.1.1.15) - Creative Enzymes

... is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO 2. In mammals, GAD exists in two ... L-glutamate α-decarboxylase; aspartate 1-decarboxylase; aspartic α-decarboxylase; L-aspartate-α-decarboxylase; γ-glutamate ... Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to ... L-glutamic acid decarboxylase; L-glutamic decarboxylase; cysteic acid decarboxylase; ...
more infohttps://www.creative-enzymes.com/product/LGlutamate-Decarboxylase-Crude-Enzyme-_16244.html

Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. | DocphinPresynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. | Docphin

Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. , Journal of the ... Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. H Mitoma S Y Song K ... Glutamic acid decarboxylase (GAD), the enzyme responsible for converting glutamate to gamma-aminobutyric acid (GABA), is a ... Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. J Neurol Sci. 2000;175( ...
more infohttps://www.docphin.com/research/article-detail/9574768/PubMedID-10785255/Presynaptic-impairment-of-cerebellar-inhibitory-synapses-by-an-autoantibody-to-glutamate-decarboxylase

GADL1 (glutamate decarboxylase like 1) - Chinchilla Research Resource DatabaseGADL1 (glutamate decarboxylase like 1) - Chinchilla Research Resource Database

... glutamate decarboxylase like 1) HGNC Alliance Mus musculus (house mouse) : Gadl1 (glutamate decarboxylase-like 1) MGI Alliance ... glutamate decarboxylase like 1) Heterocephalus glaber (naked mole-rat) : Gadl1 (glutamate decarboxylase like 1) more info ... ... glutamate decarboxylase-like 1) Alliance Chinchilla lanigera (long-tailed chinchilla) : Gadl1 (glutamate decarboxylase like 1) ... glutamate decarboxylase like 1) Sus scrofa (pig) : GADL1 (glutamate decarboxylase like 1) Chlorocebus sabaeus (African green ...
more infohttps://crrd.mcw.edu/rgdweb/report/gene/main.html?id=12361244

Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia | Orphanet Journal...Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia | Orphanet Journal...

Intra-cerebellar administration of GAD65-Ab from a SPS patient (Ab SPS) impaired the NMDA-mediated turnover of glutamate, but ... Monoclonal antibodies b78 and b96.11 showed distinct effects, with greater effects of b78 in terms of increase of glutamate ... Wu H, Jin Y, Buddhala C, Osterhaus G, Cohen E, Jin H, Wei J, Davis K, Obata K, Wu JY: Role of glutamate decarboxylase (GAD) ... Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia. ...
more infohttps://ojrd.biomedcentral.com/articles/10.1186/1750-1172-6-3

Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in...Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in...

Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in ... It also leads to persistent reductions in hippocampal glutamate decarboxylase (GAD) interneuron numbers without diminution in ... Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in ...
more infohttps://scholars.duke.edu/display/pub677875