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*  Myoglobin - Wikipedia
Myoglobin belongs to the globin superfamily of proteins, and as with other globins, consists of eight alpha helices connected ... Human globin contains 154 amino acids. Myoglobin contains a porphyrin ring with an iron at its center. A proximal histidine ... Wu G, Wainwright LM, Poole RK (2003). "Microbial globins". Advances in Microbial Physiology. Advances in Microbial Physiology. ...
https://en.wikipedia.org/wiki/Myoglobin
*  Diffusion-controlled reaction - Wikipedia
Gardner, P.R.; Gardner, D.P.; Gardner, A.P. (2015). "Globins Scavenge Sulfur Trioxide Anion Radical". Journal of Biological ...
https://en.wikipedia.org/wiki/Diffusion-controlled_reaction
*  Hemoglobin - Wikipedia
... heme/globin-containing molecules (even monomeric globin ones) that deal with gas-binding are referred to as oxyhemoglobins. In ... Nitric oxide can also be transported by hemoglobin; it is bound to specific thiol groups in the globin protein to form an S- ... NO binds reversibly to a specific cysteine residue in globin; the binding depends on the state (R or T) of the hemoglobin. The ... Such a name is given because this arrangement is the same folding motif used in other heme/globin proteins such as myoglobin. ...
https://en.wikipedia.org/wiki/Hemoglobin
*  Hemoglobinopathy - Wikipedia
Hemoglobinopathy is a kind of genetic defect that results in abnormal structure of one of the globin chains of the hemoglobin ... Thalassemias, in contrast, usually result in underproduction of normal globin proteins, often through mutations in regulatory ... The two conditions may overlap, however, since some conditions which cause abnormalities in globin proteins (hemoglobinopathy) ... Huisman THJ (1996). "A Syllabus of Human Hemoglobin Variants". Globin Gene Server. Pennsylvania State University. Retrieved ...
https://en.wikipedia.org/wiki/Hemoglobinopathy
*  Hemoglobin Hopkins-2 - Wikipedia
"N-Baltimore.html". globin.bx.psu.edu. Retrieved 2017-03-30. "Medical Archives - Personal Paper Collections: The C. Lockard ...
https://en.wikipedia.org/wiki/Hemoglobin_Hopkins-2
*  Cytoglobin - Wikipedia
Cytoglobin is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. It was ... Geuens E, Brouns I, Flamez D, Dewilde S, Timmermans JP, Moens L (Aug 2003). "A globin in the nucleus!". The Journal of ... Burmester T, Ebner B, Weich B, Hankeln T (Apr 2002). "Cytoglobin: a novel globin type ubiquitously expressed in vertebrate ... Burmester T, Ebner B, Weich B, Hankeln T (Apr 2002). "Cytoglobin: a novel globin type ubiquitously expressed in vertebrate ...
https://en.wikipedia.org/wiki/Cytoglobin
*  Variant of uncertain significance - Wikipedia
Marotta CA, Wilson JT, Forget BG, Weissman SM (1977). "Human beta-globin messenger RNA. III. Nucleotide sequences derived from ... it was known that the disease was caused by a mutation in the β-globin gene. In 1977, in the third of a series of 3 research ...
https://en.wikipedia.org/wiki/Variant_of_uncertain_significance
*  Super-enhancer - Wikipedia
Banerji J, Rusconi S, Schaffner W (December 1981). "Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences ... Evans T, Felsenfeld G, Reitman M (1990). "Control of globin gene transcription". Annual Review of Cell Biology. 6: 95-124. doi: ... high-level expression of the human beta-globin gene in transgenic mice". Cell. 51 (6): 975-85. doi:10.1016/0092-8674(87)90584-8 ...
https://en.wikipedia.org/wiki/Super-enhancer
*  Hemoglobin - Wikipedia
... heme/globin-containing molecules (even monomeric globin ones) that deal with gas-binding are referred to as oxyhemoglobins. In ... "Globin Gene Server. Pennsylvania State University. Retrieved 2008-10-12.. *^ Kikuchi, G.; Yoshida, T.; Noguchi, M. (2005). " ... The name hemoglobin is derived from the words heme and globin, reflecting the fact that each subunit of hemoglobin is a ... Such a name is given because this arrangement is the same folding motif used in other heme/globin proteins such as myoglobin.[ ...
https://en.wikipedia.org/wiki/Hemoglobin_deficiency
*  Cytochrome P450 - Wikipedia
Many animals have as many or more CYP genes than humans do. Reported numbers range from 35 genes in the sponge Amphimedon queenslandica to 235 genes in the cephalochordate Branchiostoma floridae.[30] Mice have genes for 101 CYPs, and sea urchins have even more (perhaps as many as 120 genes).[31] Most CYP enzymes are presumed to have monooxygenase activity, as is the case for most mammalian CYPs that have been investigated (except for, e.g., CYP19 and CYP5). Gene and genome sequencing is far outpacing biochemical characterization of enzymatic function, though many genes with close homology to CYPs with known function have been found, giving clues to their functionality. The classes of CYPs most often investigated in non-human animals are those either involved in development (e.g., retinoic acid or hormone metabolism) or involved in the metabolism of toxic compounds (such as heterocyclic amines or polyaromatic hydrocarbons). Often there are differences in gene regulation or enzyme function of CYPs ...
https://en.wikipedia.org/wiki/CYP450
*  Glycated hemoglobin - Wikipedia
Laboratory results may differ depending on the analytical technique, the age of the subject, and biological variation among individuals. Higher levels of HbA1c are found in people with persistently elevated blood sugar, as in diabetes mellitus. While diabetic patient treatment goals vary, many include a target range of HbA1c values. A diabetic person with good glucose control has a HbA1c level that is close to or within the reference range. The International Diabetes Federation and the American College of Endocrinology recommend HbA1c values below 48 mmol/mol (6.5 DCCT %), while the American Diabetes Association recommends HbA1c be below 53 mmol/mol (7.0 DCCT %) for most patients.[24] Recent results from large trials suggest that a target below 53 mmol/mol (7 DCCT %) for older adults with type 2 diabetes may be excessive: Below 53 mmol/mol (7 DCCT %) the health benefits of reduced A1C become smaller, and the intensive glycemic control required to reach this level leads to an increased rate of ...
https://en.wikipedia.org/wiki/Hemoglobin_A1C
*  HBG1 - Wikipedia
The order of the genes in the beta-globin cluster is: 5' - epsilon - gamma-G - gamma-A - delta - beta - 3'.[4] ... 1977). "Human beta-globin messenger RNA. I. Nucleotide sequences derived from complementary RNA". J. Biol. Chem. 252 (14): 5019 ... The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains ... 1993). "Normal delta-globin gene sequences in Sardinian nondeletional delta beta-thalassemia". Hemoglobin. 16 (6): 503-9. doi: ...
https://en.wikipedia.org/wiki/HBG1
*  HBE1 - Wikipedia
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains ... Tuan D, Solomon W, Li Q, London IM (1985). "The "beta-like-globin" gene domain in human erythroid cells". Proc. Natl. Acad. Sci ... The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5' - epsilon - gamma- ... 1977). "Human beta-globin messenger RNA. I. Nucleotide sequences derived from complementary RNA". J. Biol. Chem. 252 (14): 5019 ...
https://en.wikipedia.org/wiki/HBE1
*  Bryant Villeponteau - Wikipedia
Villeponteau, B., Landes, G.M., Pankratz, M.J., and Martinson, H.G. (1982). The chicken beta globin gene region. Delineation of ... Lois, R., Freeman, L., Villeponteau, B., and Martinson, H.G. (1990). Active beta-globin gene transcription occurs in methylated ... Villeponteau, B., and Martinson, H.G. (1981). Isolation and characterization of the complete chicken beta-globin gene region: ... where he carried out genomic cloning of the B-globin gene cluster in Chickens.... He continued in the same department for six ...
https://en.wikipedia.org/wiki/Bryant_Villeponteau
*  Beta thalassemia - Wikipedia
The technology is based on delivery of a lentiviral vector carrying both the human β-globin gene and an ankyrin insulator to ... This test is used to investigate deletions and mutations in the alpha- and beta-globin-producing genes. Family studies can be ... Most often, mutations occur in the promoter regions preceding the beta-globin genes. Less often, abnormal splice variants are ... Deletion forms: Deletions of different sizes involving the β globin gene produce different syndromes such as (βo) or hereditary ...
https://en.wikipedia.org/wiki/Beta_thalassemia
*  Thalassemia - Wikipedia
... production of the β globin chain is affected. The β globin chains are encoded by a single gene on chromosome 11; α globin ... The severity of alpha and beta thalassemia depends on how many of the four genes for alpha globin or two genes for beta globin ... α Thalassemias result in decreased alpha-globin production, therefore fewer alpha-globin chains are produced, resulting in an ... Only one of the two β globin alleles contains a mutation, so β chain production is not terribly compromised and patients may be ...
https://en.wikipedia.org/wiki/Thalassemia
*  HBB - Wikipedia
Expression of beta globin and the neighbouring globins in the β-globin locus is controlled by single locus control region (LCR ... Beta globin (also referred to as HBB, β-globin, haemoglobin beta, hemoglobin beta, or preferably haemoglobin subunit beta) is a ... The order of the genes in the beta-globin cluster is 5' - epsilon - gamma-G - gamma-A - delta - beta - 3'. HBB interacts with ... HBB protein is produced by the gene HBB which is located in the multigene locus of β-globin locus on chromosome 11, ...
https://en.wikipedia.org/wiki/HBB
*  Hemoglobin subunit zeta - Wikipedia
... while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene ... Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, ... Proudfoot NJ, Gil A, Maniatis T (1983). "The structure of the human zeta-globin gene and a closely linked, nearly identical ... 1974). "Nucleotide Sequences of Human Globin Messenger RNA". Proc. Natl. Acad. Sci. U.S.A. 71 (6): 2300-4. doi:10.1073/pnas. ...
https://en.wikipedia.org/wiki/Hemoglobin_subunit_zeta
*  Neuroglobin - Wikipedia
Neuroglobin is a member of the vertebrate globin family involved in cellular oxygen homeostasis. It is an intracellular ... It is of ancient evolutionary origin, and is homologous to nerve globins of invertebrates. Recent research on Neuroglobin ... Burmester T, Weich B, Reinhardt S, Hankeln T (September 2000). "A vertebrate globin expressed in the brain". Nature. 407 (6803 ... science.gov, Neuroglobins, Pivotal Proteins Associated with Emerging Neural Systems and Precursors of Metazoan Globin Diversity ...
https://en.wikipedia.org/wiki/Neuroglobin
*  Colworth Medal - Wikipedia
Flavell, R. A. (1983). "The globin genes of rabbit and man. The eighteenth Colworth medal lecture". Biochemical Society ...
https://en.wikipedia.org/wiki/Colworth_Medal
*  Channichthyidae - Wikipedia
Cocca, E (1997). "Do the hemoglobinless icefishes have globin genes?". Comp. Biochem. Physiol. A. 118: 1027-1030. doi:10.1016/ ...
https://en.wikipedia.org/wiki/Channichthyidae
*  Locus control region - Wikipedia
The β-globin LCR in mice and humans is found 6-22 kb upstream of the first globin gene (epsilon). Although studies have been ... Although the name implies that the LCR is limited to a single region, this implication only applies to the β-globin LCR. Other ... It functions in a copy number-dependent manner and is tissue-specific, as seen in the selective expression of β-globin genes in ... This leads to decreased expression of β-globin genes, which can cause β-thalassemia in humans and mice. Li Q, Peterson KR, Fang ...
https://en.wikipedia.org/wiki/Locus_control_region
*  Once Upon a Time... Life - Wikipedia
... and his inquisitive and mischievous friend Globin. They carry oxygen bubbles or carbon dioxide bubbles in a back pouch, ... Plasmus and Globina for Hemo and Globin, Corpo for Jumbo; Toxicus, Germus and Infectius for the bacterium characters; Virulus ...
https://en.wikipedia.org/wiki/Once_Upon_a_Time..._Life
*  Mu hemoglobin - Wikipedia
Mu hemoglobin is a human alpha-like globin gene named HBM gene. The mRNA is expressed at moderate levels, but the protein is ... August 2005). "A newly discovered human alpha-globin gene". Blood. 106 (4): 1466-72. doi:10.1182/blood-2005-03-0948. PMC ... "A review of the molecular genetics of the human alpha-globin gene cluster". Blood. 73 (5): 1081-104. PMID 2649166. Fischel- ... Ghodsian N, Nicholls RD, Higgs DR (November 1987). "Unusual features of CpG-rich (HTF) islands in the human alpha globin ...
https://en.wikipedia.org/wiki/Mu_hemoglobin
*  Fotis Kafatos - Wikipedia
Efstratiadis, A.; Kafatos, F. C.; Maxam, A. M.; Maniatis, T. (1976). "Enzymatic in vitro synthesis of globin genes". Cell. 7 (2 ...
https://en.wikipedia.org/wiki/Fotis_Kafatos