According to Duncan and Keller, "the possibility that most or even all positive [candidate gene-by-environment interaction] ... Fergusson DM, Boden JM, Horwood LJ, Miller A, & Kennedy MA (2012). Moderating role of the MAOA genotype in antisocial behaviour ... Duncan LE, & Keller MC (2011). A critical review of the first 10 years of candidate gene-by-environment interaction research in ... an interaction between this promoter and a second promoter of the MAOA gene, interactions between the MAOA gene promoter and ...

The bi-stable switch would enable T cells to integrate signals from pathogens, hormones, cell-cell interactions, and soluble ... each with a characteristic gene regulatory network. The bi-stable switch would enable T cells to integrate signals from ... pathogens, hormones, cell-cell interactions, and soluble mediators and respond in a biologically appropriate manner. Finally, ... A deep understanding of molecular mechanisms relevant to gene-environment interactions is needed to deliver etiology-based ...

... interaction model for the growth of short-rotation coppice willow and in silico exploration of genotype x environment effects. ... Secondary cell wall composition and candidate gene expression in developing willow (Salix purpurea) stems. Planta. 239, pp. ... interaction model for the growth of short-rotation coppice willow and in silico exploration of genotype x environment effects. ... Secondary cell wall composition and candidate gene expression in developing willow (Salix purpurea) stems. A - Papers appearing ...

Gourdine J-L, Riquet J, Rosé R, et al. Genotype by environment interactions for performance and thermoregulation responses in ... Muñoz M, Bozzi R, García F, et al. Diversity across major and candidate genes in European local pig breeds. PLoS One. 2018;13( ... Iannuccelli N, Mary N, Bonnet N, et al. Genotyping data of French wild boar populations using porcine genome-wide genotyping ... Bovo S, Schiavo G, Ribani A, et al. Describing variability in pig genes involved in coronavirus infections for a One Health ...

Gene-environment interactions for obesity-related phenotypes have been shown in candidate gene (Guo et al. 2007) and twin and ... 2011), this test is more relevant when one measured genotype is interacted with one measured environment. When hundreds of ... We suggest that this typology be reserved for studies focusing on interactions between a candidate gene and the environment ( ... Is the Gene-Environment Interaction Paradigm Relevant to Genome-Wide Studies? The Case of Education and Body Mass Index Jason D ...

A pilot study of gene/gene and gene/environment interactions in Alzheimer disease. ... Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic ... ACE I/D genotype, adiposity, and blood pressure in children. [PMID 19539712] An age effect on the association of common ... detection of gene-gene and gene-environment interactions [PMID 14986105] Common variants of ACE contribute to variable age-at- ...

Gene-environment interactions in obesity.. Candidate gene studies in obesity and related traits. ... A meta-analysis including 9,038 individuals confirms an interaction effect between depression and fto genotype on BMI ... hypothesis diabetes eating eating disorder food addiction FTO gene gene-environment Genes genetics genome-wide association ... Candidate gene studies in obesity and related traits.. Genetic studies of metabolic disease - extreme phenotypes and common ...

General Environments Journal Article * Exploring candidate gene associations with neuropsychological performance Journal ... A Preliminary Analysis of Interactions Between Genotype, Retrospective ADHD Symptoms, and Initial Reactions to Smoking in a ... Environment and Public Health - Cohort Studies PubMed MeSh Term narrower concept * Environment and Public Health - National ... Person-environment interaction in the prediction of alcohol abuse and alcohol dependence in adulthood Journal Article ...

Estimating Genotype × Environment Interaction for Groundnut Seed Yield across Different Ecological Zones Muhammad Jahanzaib, ... Molecular Characterization of BrMYB73: A Candidate Gene for the Purple-Leaf Trait in Brassica rapa Jiao Wang, Tongbing Su, ... Regulation Behavior of RSuS-1 Promoter using uidA Gene in Rice (Oryza sativa) Shaukat Ali, Muhammad Amir Zia, Hu Ye Sun, Shehla ... Evaluating the Impact of Seed Rate and Sowing Dates on Wheat Productivity in Semi-Arid Environment Shahzad Tahir, Ashfaq Ahmad ...

FoxO1, A2M and TGF-B1: three novel genes predicting depression in gene X environment interactions are identified using cross- ... gene regulate the risk for depression in patients exposed to interferon (INF)-α.12 Interestingly, carriers of the 2 genotypes ... 9 Based largely on candidate-gene studies, findings indicate that common genetic variants are involved in both immune ... "gene-environment" interaction. For example, Kovács and colleagues10 report that the high-IL-1β T allele of the rs16944 SNP ...

Highly significant genotype×environment interactions were observed for both micronutrients; grain Fe showed greater variation ... QTLs were analyzed in-silico to identify underlying candidate genes, 62 candidate genes involved in Fe/Zn metabolism were ... Identification of QTLs and Underlying Candidate Genes Controlling Grain Fe and Zn Concentration in Sorghum [Sorghum bicolor (L ... QTLs/candidate/novel genes along with the marker/genetic resources identified through this study can help in developing high Fe ...

Even the presence of one copy of a variant allele in the CYP1A1 gene can predispose CRC risk. Additional studies should also ... were analyzed for five SNPs using conventional PCR and TaqMan genotyping assays. The SNPStats software was utilized to choose ... We explored whether allelic variants of the GSTM1, GSTT1, CYP450 (rs4646903 and rs1048943), and TP53 (rs1042522) genes ... Several candidate genes and genetic variants have been associated with morbidity and mortality among patients with CRC. ...

Kraft P. Multiple comparisons in studies of gene × gene and gene × environment interaction. Am J Hum Genet ... Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing ... For candidate gene pathways, Millstein et al. (54) have proposed a "Focused Interaction Testing Framework" that seems to ... gene-gene or gene-environment associations, or various subgroup analyses. Rather than routinely posting such an enormous number ...

... and their follow-up studies still lack power to conclusively evaluate the role of gene/gene and gene/environment interaction in ... Since 2006, the genotyping of sets of DNAs on hundreds of thousand of loci has become routine practice, thus opening the Genome ... Taking advantage of the new generation sequencing technology, search for very rare variants in candidate functional regions may ... Although some of the cancer-associated markers are located within or in proximity of genes with conspicuous functional ...

The possibility of genotype-environment interaction for memory performance and change was examined in 150 monozygotic (MZ) twin ... Multiple variability genes were found for longitudinal change in a semantic memory task including candidates coding for ... that genotype was associated with intrapair variability and thus suggestive of genotype-nonshared environment interactions. ... The Interplay of Genes and Environment across Multiple Studies (IGEMS) is a consortium of 18 twin studies from 5 different ...

We also selected seven medulloblastoma predisposition genes for investigation using a candidate gene approach: APC, BRCA2, ... Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample. ... Thirteen of these variants were genotyped, whereas 46 were imputed. Genotyped variants were further investigated in a ... However, these studies usually focus on one disorder and/or on one HLA candidate gene, often with small samples. Here, we ...

Behaviours are all interactions of an individual with its environment. All environmental stimuli are integrated and processed ... we work with knockout animals that have targeted mutations in genes that are high-potential candidates for disease. ... Particularly, we are studying the role of a Neuregulin-1 knockout and GPCR12 knockout in health and disease; the genotype of ... Genes carry the fundamental information to build and maintain cells, including neurons. Any gene of a cell can undergo changes ...

In addition, we discuss reports on the interactions of OXT and AVP receptor genes and genes involved in other pathways (such as ... In addition, we discuss reports on the interactions of OXT and AVP receptor genes and genes involved in other pathways (like ... As an alternative, some studies are using polygenic approaches, and consider the contributions of other genes and pathways, ... those of dopamine, serotonin, and reelin), as well as research that has shed some light on the impact of gene polymorphisms on ...

Genotype-by-Environment Interaction and Plasticity: Exploring Genomic Responses of Plants to the Abiotic Environment journal, ... 10) Vermerris W, Fear J, Saballos A, Murray SC, Rooney WL, Kresovich S. Identification of candidate genes for sucrose ... but not all QTLs were detected in all environments, providing evidence for genotype x environment interactions. This finding ... One of these genes is a sucrose synthase gene. This cluster also contains 10 genes from the QTL. 6) Among these co-expressed ...

... most significantly associated with severity of infection is located in a biologically plausible candidate gene (CDON, a member ... Future investigations using larger samples, narrowed phenotypes, and advances in both genotyping and analytical methodologies ... including an interaction of host SNP with bacterial genotype, and adjusting for age (by decade), sex, the 6 significant ... Kraft P, Yen Y, Stram DO, Morrison J, Gauderman WJ: Exploiting gene-environment interaction to detect genetic associations. Hum ...

Query Trace: Gene-environment interaction[original query]. A Case-Only Genome-Wide Interaction Study of Smoking and Bladder ... Genotype-environment interaction on arterial stiffness: A pedigree-based study]. Beijing da xue xue bao. Yi xue ban = Journal ... Gene-environment analyses reveal novel genetic candidates with prenatal tobacco exposure in relation to risk for childhood ... A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry. Breast cancer research ...

... microsatellite marker within and around these four candidate genes were genotyped in 30 chromosome 7q31 linked families. ... the interaction of multiple genes within an individuals genome and the existence of distinct genes and gene combinations among ... uterine environment (decreased norepinephrine relative to dopamine), which, in conjunction with genotypic susceptibility of the ... Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene.. Mol ...

QTLs and candidate genes detected in our study for yield-related traits under stripe rust stress will facilitate elucidating ... Further, 21 candidate genes within three potentially novel QTLs were identified, they were mainly involved in the regulation of ... in at least two test environments under stripe rust stress conditions. Of them, ten QTLs were overlapped or very close to the ... The box plots of eight yield-related traits in multiple environments. It clearly showed that the genotype-by-year interaction ...

... which might regulate plant cell wall metabolism are the candidate genes for qPH10. Here, an ultra-high density accurate linkage ... Interestingly, pQTL10, which influences all three of these traits, was stably detected in three environments on chromosome 10 ... The quality and accuracy of the bin map for QTL detection was verified by the mapping of a known gene, pericarp color 1 (P1), ... This map will facilitate identification of genes and exploration of QTL for plant architecture in maize. It will also be ...

Candidate genes shown to express under S. sclerotiorum infection in other studies, including cell wall receptor kinase, COI1, ... The host-pathogen interaction is complex, with partial resistance in the host inherited as a quantitative trait with low to ... Ascomycota, Chromosome Mapping, Chromosomes, Plant, Disease Resistance, Genetic Linkage, Genotype, Peroxidase, Phaseolus, Plant ... conditioning partial resistance to white mold from individual QTL identified across multiple populations and environments. The ...

Epigenetics is a change in gene expression that results from gene-environment interactions. This is mediated by DNA methylation ... and a candidate gene on chromosome 1 called presenilin-2 (PS2). The 2 putative products of these candidate genes, PS1 and PS2, ... Other than the apolipoprotein E epsilon 4 (APOE E4) genotype, no polymorphisms in other genes have been consistently found to ... A significant proportion of early-onset autosomal-dominant AD cases have been linked to a candidate gene on chromosome 14 ( ...