Loading...
*  Genome-wide association study of lung function decline in adults with and without asthma | RTI
Objective: We conducted the first genome-wide association study on the age-related decrease in FEV1 and its ratio to forced ... Genome-wide association studies have identified determinants of chronic obstructive pulmonary disease, asthma, and lung ... Objective: We conducted the first genome-wide association study on the age-related decrease in FEV1 and its ratio to forced ... Background: Genome-wide association studies have identified determinants of chronic obstructive pulmonary disease, asthma, and ...
https://www.rti.org/publication/genome-wide-association-study-lung-function-decline-adults-and-without-asthma
*  Optimal designs for two-stage genome-wide association studies - Skol - 2007 - Genetic Epidemiology - Wiley Online Library
Optimal designs for two-stage genome-wide association studies. Genet. Epidemiol., 31: 776-788. doi: 10.1002/gepi.20240 ... If you are a society or association member and require assistance with obtaining online access instructions please contact our ... Optimal designs for two-stage genome-wide association studies. *Andrew D. Skol1,2,*, ...
http://onlinelibrary.wiley.com/doi/10.1002/gepi.20240/references
*  Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study - Nottingham...
To better understand the genetic basis of dementia with Lewy bodies, we have done a genome-wide association study with the aim ... Methods In this two-stage genome-wide association study, we collected samples from white participants of European ancestry who ... Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study ... Interpretation Despite the small sample size for a genome-wide association study, and acknowledging the potential biases from ...
http://eprints.nottingham.ac.uk/48193/
*  A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants....
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants ... A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants ... Here we report on a study of ,12 million variants, including 163,714 directly genotyped, mostly rare, protein-altering variants ... Although wet and dry AMD subtypes exhibit predominantly shared genetics, we identify the first genetic association signal ...
https://scholars.duke.edu/display/pub1111001
*  Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome...
Recent genome-wide association studies (GWAS) and subsequent meta-analyses have identified over 25 SNPs at 18 loci, together ... Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome ... Genome-Wide Association Study; Genotype; Humans; Linkage Disequilibrium; Male; Neoplasms, Germ Cell and Embryonal; Odds Ratio; ... Here, we report new genotyping of eight SNPs showing some evidence of association in combined analysis of Stage 1 and Stage 2 ...
http://www.forskningsdatabasen.dk/catalog/272500784
*  Ml-stat-talks] Wed 9/21: Barbara Englehardt on genome-wide associations
Genome-wide associations studies with complex phenotypes: How statistics can help Abstract: Genome-wide association studies ( ... Ml-stat-talks] Wed 9/21: Barbara Englehardt on genome-wide associations. David Blei blei at CS.Princeton.EDU Tue Sep 20 17:14: ... Previous message: [Ml-stat-talks] Wed 9/21: Barbara Englehardt on genome-wide associations ... Previous message: [Ml-stat-talks] Wed 9/21: Barbara Englehardt on genome-wide associations ...
https://lists.cs.princeton.edu/pipermail/ml-stat-talks/2011-September/000095.html
*  Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. - Oxford...
We aimed to generate a multilocus genetic risk score (GRS) for IS based on genome-wide association studies data from clinical- ... We selected variants that had reached genome-wide significance in previous association studies on established risk factors for ... on sex significantly improved the prediction of IS in the combined clinic-based samples but not in the population-based studies ... pressure significantly associated with IS both in the case-control samples and in the prospective population-based studies. ...
https://www.neuroscience.ox.ac.uk/publications/446853
*  genome-wide association studies - Genetic Future
genome-wide association studies. Genetic Future. Category archives for genome-wide association studies. The promise and ... The genome-wide association study has been the technique du jour in human genetics for much of the last two years. It's a pure ... The successes of genome-wide association studies (GWAS) in identifying genetic risk factors for common diseases have been ... David Goldstein on the failures of genome-wide association studies. Posted by Daniel MacArthur on September 16, 2008 ...
http://scienceblogs.com/geneticfuture/category/genomewide_association_studies/page/3/
*  A genome-wide association study of myasthenia gravis. - PubMed - NCBI
Regional Association Plots Across Loci Identified by the Genome-Wide Association Study of Myasthenia Gravis ... A genome-wide association study of myasthenia gravis.. Renton AE1, Pliner HA1, Provenzano C2, Evoli A3, Ricciardi R4, Nalls MA5 ... To identify genetic variants that alter susceptibility to myasthenia gravis, we performed a genome-wide association study. ... Myasthenia Gravis Cases and P Values From the Genome-Wide Association Study of Myasthenia Gravis ...
https://www.ncbi.nlm.nih.gov/pubmed/?term=25643325
*  Interpreting Meta-Analyses of Genome-Wide Association Studies
In this paper, we propose a method that helps such interpretation, in addition to a new association testing procedure that is ... Since it is costly to conduct a study collecting such a large sample, a practical alternative is to combine multiple ... These factors can cause the effect size of the causal variant to differ between the studies, a phenomenon called heterogeneity ... However, many factors, such as genetic or environmental factors, can differ between the studies combined in a meta-analysis. ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002555
*  Genome-wide association study - Wikipedia
In genetics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or ... "How to read a genome-wide association study". Genomes Unzipped. Consortia of genome-wide association studies (GWAS) - by ... This type of study has been named genome-wide association study by proxy (GWAX). A central point of debate on GWA studies has ... "Genome-Wide Association Studies". National Human Genome Research Institute. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, ...
https://en.wikipedia.org/wiki/Genome-wide_association_study
*  Genome-wide association study of schizophrenia in Ashkenazi Jews. - PubMed - NCBI
Genome-wide association study of schizophrenia in Ashkenazi Jews.. Goes FS1, McGrath J1, Avramopoulos D1,2, Wolyniec P1, ... We performed a genome-wide association analysis (GWAS) of 592 cases and 505 controls of AJ ancestry ascertained in the US. ... We found no genome-wide significant associations in the U.S. sample or in the combined US/Israeli AJ meta-analysis of 1505 ... The meta-analysis of the U.S. sample with the PGC2 results provided initial genome-wide significant evidence for six new loci. ...
https://www.ncbi.nlm.nih.gov/pubmed/26198764
*  WHI - Genome Wide Association Studies (GWAS)
Genome Wide Association Studies (GWAS). When you joined the Women's Health Initiative many years ago, you may recall providing ... One of the most significant ways may come from using those stored blood samples as part of a Genome Wide Association Study, or ... Is each person's genome unique?. Humans come in many shapes and sizes, but we're all very similar at the genome level. In fact ... GENETIC STUDIES MAY ENHANCE HEALTH CARE. Genetic studies help us understand the link between genes and certain diseases. This ...
https://www.whi.org/Stories/Genome%20Wide%20Association%20Studies%20
*  Genome-wide Association Study of Autism Characterized by Developmental Regression | Autism Speaks
Autism SpeaksScienceGrant SearchResultsGenome-wide Association Study of Autism Characterized by Developmental Regression ... New Meta-analysis Confirms: No Association between Vaccines and Autism *. Whole genome sequencing reveals new type of genetic ...
https://www.autismspeaks.org/science/grants/genome-wide-association-study-autism-characterized-developmental-regression?destination=about-us%2Fgrant-search%2Ftaxonomy%3A10086.10171%3Forder%3Dtitle_2%26sort%3Dasc
*  Changes related to "Genome Wide Association Studies" - CBG
Changes related to "Genome Wide Association Studies". ← Genome Wide Association Studies. Jump to: navigation, search ...
https://www2.unil.ch/cbg/index.php?title=Special:RecentChangesLinked&limit=100&target=Genome_Wide_Association_Studies
*  Genome-wide Association Study of Pituitary Tumors - Full Text View - ClinicalTrials.gov
Genome-wide Association Study of Pituitary Tumors. The safety and scientific validity of this study is the responsibility of ... The investigators are going to use genome-wide association study to identify genes that may be related to pituitary adenomas. ... Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information ... Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information ...
https://clinicaltrials.gov/ct2/show/NCT01442220?recr=Open&cond=%22Pituitary+Neoplasms%22&rank=14
*  Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
2014) Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study. PLoS ONE 9(4): e91621. pmid:24714607 * ... 2015) Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study. PLoS ONE 10(5): e0129524. ... PLOS ONE promises fair, rigorous peer review, broad scope, and wide readership - a perfect fit for your research every time. ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129524
*  Genome-wide Association Study of Prostate Cancer Mortality | Cancer Epidemiology, Biomarkers & Prevention
In prostate cancer genetic association studies for risk, a combined analysis of two genome-wide association studies (GWAS) ... Genome-wide association study. Affymetrix scan.. The samples from the PHS and HPFS were included in the genome scan. DNA was ... Genome-wide Association Study of Prostate Cancer Mortality. Kathryn L. Penney, Saumyadipta Pyne, Fredrick R. Schumacher, ... Genome-wide Association Study of Prostate Cancer Mortality. Kathryn L. Penney, Saumyadipta Pyne, Fredrick R. Schumacher, ...
http://cebp.aacrjournals.org/content/19/11/2869
*  Gene Expression: Genome-wide association studies in the UK
Genome-wide association studies in the UK posted by p-ter @ 6/06/2007 05:59:00 PM Genome-wide association studies in the UK ... Results from the most ambitious (and expensive) set of genome-wide association studies for common diseases were published today ... Evolutionary Genetics: Case Studies and Concepts. Narrow Roads of Gene Land 1. Narrow Roads of Gene Land 2. Narrow Roads of ... Evolutionary Genetics: Case Studies and Concepts. Narrow Roads of Gene Land 1. Narrow Roads of Gene Land 2. Narrow Roads of ...
http://www.gnxp.com/blog/2007/06/genome-wide-association-studies-in-uk.php
*  23andMe performs genome-wide association study on NFL players, fails to find athlete genes | WIRED
The shocking result: The study did not find the tested players to be genetic outliers, suggesting \[…\] ... but a press release announced today suggests that personal genomics company 23andMe has performed a genome-wide association ... study comparing 100 current or former professional NFL players with a set of controls of unspecified sample size. ... 23andMe performs genome-wide association study on NFL players, fails to find athlete genes. Details are pretty sketchy, but a ...
https://www.wired.com/2009/10/23andme-performs-genome-wide-association-study-on-nfl-players-fails-to-find-athlete-genes/
*  Difference between revisions of "Genome Wide Association Studies" - CBG
Genome Wide Association Studies (GWAS) search for correlations between genetic markers (usually Single Nucleotide Polymorphisms ... Genome Wide Association Studies (GWAS) search for correlations between genetic markers (usually Single Nucleotide Polymorphisms ... Genome Wide Association Studies (GWAS) search for correlations between genetic markers (usually Single Nucleotide Polymorphisms ... Retrieved from "http://www2.unil.ch/cbg/index.php?title=Genome_Wide_Association_Studies&oldid=3383" ...
https://www2.unil.ch/cbg/index.php?title=Genome_Wide_Association_Studies&diff=3383&oldid=854
*  Genome-wide Association Study: Not so benign | eLife
... is linked to genes that are responsible for preserving genome integrity and promoting genitourinary development. ... A genome-wide association study on leiomyomas.. The study performed by Välimäki et al. had five phases. (1) Discovery: regions ... A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic ... A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids * PC Cha ...
https://elifesciences.org/articles/42181
*  Genome-Wide Association Study of Retinopathy in Individuals Without Diabetes
... Author: Jensen, Richard A.; Sim, Xueling; Li, ... Genome-Wide Association Study of Retinopathy in Individuals Without Diabetes. DSpace/Manakin Repository. * DASH Home ... We conducted a genome-wide association study (GWAS) of mild retinopathy in persons without diabetes. Methods: A working group ... Genome-wide association study of retinopathy in individuals without diabetes. PLoS ONE 8(2): e54232.. ...
https://dash.harvard.edu/handle/1/10613648
*  Validation Is Critical for Genome-Wide Association Study-Based Associations
... found through the use of a genome-wide association study, needs to be critically evaluated until validation studies show that ...
https://insights.ovid.com/ajtr/201702000/00024798-201702000-00005
*  Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
Therefore, we performed a genome wide association (GWA) study of CMH in Caucasian populations. Methods: GWA analysis was ... "Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study." PLoS ONE 9 (4): e91621. doi:10.1371/journal. ... A strong association with CMH, consistent across all cohorts, was observed with rs6577641 (p = 4.25×10−6, OR = 1.17), located ... Additional studies were performed to test the functional relevance of the most significant single nucleotide polymorphism (SNP ...
https://dash.harvard.edu/handle/1/12152914