Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
In order to test whether in vivo transduction of a murine tumor could be used to treat the disease, an experiment was performed ... Of these, extensive genetic and biochemical characterization have been performed on Ad2 and Ad5. Id. at 618. Based upon these ... to deletions which can be made in the dispensable E3 region and in E1using complementation on 293 cells, and to the fact that ... 18). These vectors are used as pseudo-HIV to test-activate tat-dependent HSVTK vectors.. 1. The His.sup.r expression vector ...http://www.patentgenius.com/patent/5997859.html
Frontiers | Analysis of Magnaporthe oryzae Genome Reveals a Fungal Effector, Which Is Able to Induce Resistance Response in...
Genetic complementation test also proved that Mo-01947_9 protein induces avirulence response in the pathogen in the presence of ... Genetic complementation test also proved that Mo-01947_9 protein induces avirulence response in the pathogen in the presence of ... Genetic Complementation Test of Candidate AvrPi54 Gene. Complementation of avirulence function of the cloned candidate AvrPi54 ... Genetic complementation test also proved that Mo-01947_9 protein induces avirulence response in the pathogen in presence of ...https://www.frontiersin.org/articles/10.3389/fpls.2016.01140/full
Molecular cloning and functional analysis of a blue light receptor gene MdCRY2 from apple (Malus domestica).
Genetic Complementation Test. Light. Malus / genetics*, growth & development, metabolism. Molecular Sequence Data. Plant ... the interaction between MdCRY2 and AtCOP1 using a yeast two-hybrid assay and a bimolecular fluorescence complementation assay. ...http://www.biomedsearch.com/nih/Molecular-cloning-functional-analysis-blue/23314496.html
Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes.
Genetic Complementation Test. Humans. Microbodies / metabolism*, ultrastructure. Oxidation-Reduction. Zellweger Syndrome / ... Since this disorder is genetically heterogeneous and several complementation groups are known, we were able to study the ... normalization of peroxisomal activity during the process of complementation. The restoration of catalase and dihydroxyacetone ...http://www.biomedsearch.com/nih/Complementation-in-Zellweger-syndrome-biochemical/1511996.html
Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants |...
Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. ... Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. ... Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. ... Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants ...http://www.genetics.org/content/201/3/1263
MeSH ORA framework: R/Bioconductor packages to support MeSH over-representation analysis | BMC Bioinformatics | Full Text
Genetic Complementation Test (+8). Promoter Regions, Genetic (+24). PA5471. Ribosomes. Pseudomonas aeruginosa ... 2) Multiplicity of tests * As described above, in ORA, several thousand statistical tests are conducted simultaneously. Such an ... The hypergeometric test (or Fisher's exact test) is widely used to calculate such probabilities. Several thousand statistical ... Genetic Epidemiol. 2002; 23:70-86.View ArticleGoogle Scholar. *. Durinck S, Spellman PT, Birney E, Huber W. Mapping identifiers ...https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0453-z
Smyd3 methylates H4K5 in vitro and in vivo. (A) Methyla | Open-i
Genetic Complementation Test. *HeLa Cells. *Humans. *Methylation. *Mice. *Mice, Inbred C57BL. *Mice, Knockout ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3368817_epi-7-340-g2&req=4
The CG12120 Gene Product Possesses NBAD Hydrolase and N | Open-i
Genetic Complementation Test. *Molecular Sequence Data. *Mutation. *Sequence Homology, Amino Acid. Related in: MedlinePlus ... To test whether CG12120 possesses these predicted activities, we produced recombinant CG12120 protein using a baculovirus ... To test whether CG12120 possesses these predicted activities, we produced recombinant CG12120 protein using a baculovirus ... This is, to our knowledge, the first molecular genetic characterization of NBAD hydrolase and carcinine hydrolase activity in ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC1285064_pgen.0010063.g004&req=4
ZFIN Publication: Abdelilah et al., 1996
Genetic Complementation Test. *Mutation*. *Nerve Degeneration/genetics. *Neurons/physiology*. *Phenotype. *Rhombencephalon/ ... To prevent accidental cell death, mechanisms that trigger programmed cell death, as well as the genetic components of the cell ... The mutations presented here might provide a genetic framework to aid in the understanding of the etiology of degenerative and ...http://zfin.org/ZDB-PUB-970210-18
ZFIN Publication: Brand et al., 1996
Genetic Complementation Test; Mesoderm/pathology; Motor Neurons/pathology; Mutation*; Nervous System/embryology; Zebrafish/ ... We also find fusions of the ventral neurocranium for all midline mutants tested, which may reveal a hitherto unrecognized ...http://zfin.org/ZDB-PUB-970210-11
Welcome to LibAge, the ageing reference resource
Entries tagged Genetic Complementation Test (98). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... A curated database of genes associated with dietary restriction in model organisms either from genetic manipulation experiments ...http://la.ageing-map.org/entries/tags/193/
A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen...
For a number of case studies, additional experiments (such as in vivo genetic complementation) were performed to determine ... Here, we describe the use of nuclear magnetic resonance (NMR)-based ligand screening as a tool for testing functional ... The functional annotation of MA4265 was further tested using genetic complementation studies. The E. coli genome contains three ... Gene complementation. Genetic complementation of E. coli mutants by the MA genes was performed with E. coli deletion mutants ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-12-S1-S7
Effects of mutating α-tubulin lysine 40 on sensory dendrite development | Journal of Cell Science
Genetic complementation tests also unexpectedly revealed that αTub84D is a non-essential gene (Table 1). Combined, these data ... 1A). We tested whether the function of the α-tubulin C-terminal tails from flies and mammals might be conserved despite these ... Two-tailed Student's t-tests were used to compare two conditions. *P=0.05-0.01; **P=0.01-0.001; ***P=0.0001-0.001; ****P,0.0001 ... To test the role of αTub84B K40 acetylation in survival and neuronal morphogenesis, we introduced K40A and K40R mutations to ...http://jcs.biologists.org/content/130/24/4120?utm_source=INT&utm_medium=FP&utm_campaign=JCS_Snippet&utm_content=130-4120
000646 - A/J
A/J inbred mice are widely used to model cancer and for carcinogen testing given their high susceptibility to carcinogen- ... Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further ... as confirmed by a genetic complementation test. Birth Defects Res A Clin Mol Teratol 76(8):574-9. PubMed: 16998816MGI: J:117594 ... In addition, a standard genetic test of allelism between clf1 and a Wnt9b targeted mutation demonstrated noncomplementation, ...https://www.jax.org/strain/000646
000653 - BUB/BnJ
Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further ... The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic ... Genetic influence on electrocardiogram time intervals and heart rate in aging mice. Am J Physiol Heart Circ Physiol 296(6): ... Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains. Aging Cell 9(5):823-36PubMed: ...https://www.jax.org/strain/000653
Protocols and Video Articles Authored by Joshua T. Gamse
Linkage analysis and genetic-complementation testing indicate that lor is an allele of tbx2b/fby (from beyond). fby was ... To test for developmental roles of scn8a, we knocked down Nav1.6a protein using antisense morpholinos. Na+ channel protein and ... To resolve the paradox that flhand tbx2b mutants have opposite phenotypes but have been placed in the same genetic pathway, we ... The zebrafish has proven to be a useful model to explore the genetic basis of neuroanatomical asymmetry in the developing ...https://www.jove.com/author/Joshua+T._Gamse
A Putative Catenin-Cadherin System Mediates Morphogenesis of the Caenorhabditis elegans Embryo | JCB
Standard genetic complementation tests and mapping ordered the Hmp mutations into the following three complementation groups. ... Listed below are the marker mutations and genetic deficiencies obtained from the C. elegans Genetic Stock Center (Bristol, ... To test whether hmp-2 or hmr-1 gene activity is required to localize HMP-1 protein to adherens junctions, we stained hmp-2 and ... For the seven hmp-1 alleles tested (zu244, zu278, zu349, zu365, zu399, zu404, and ca202), transgenic animals that are not ...http://jcb.rupress.org/content/141/1/297?ijkey=1e18fdfd971c8d06a5ab743fe56bc4702b6be650&keytype2=tf_ipsecsha
Pre-binding of small protein B to a stalled ribosome triggers trans-translation.
Blotting; Northern, Cell Division, Centrifugation; Density Gradient, Escherichia coli/metabolism, Genetic Complementation Test ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:102123
"In vitro CpG methylation increases the transformation efficiency of Bo" by Qiang Chen, Joshua Richard Fischer et al.
To test whether a methylation-sensitive restriction system contributes to poor B. burgdorferi transformability, shuttle ... The utility of in vitro methylation for the genetic manipulation of B. burgdorferi was exemplified by the ease of plasmid ... complementation of a B. burgdorferi B31 A3 BBK32 kanamycin-resistant (B31 A3 BBK32::Kan(r)) mutant, deficient in the expression ... as to hinder the genetic study of putative virulence factors. Two putative restriction-modification (R-M) systems, BBE02 ...https://escholarship.umassmed.edu/gsbs_sp/1402/
"Dominant negative mutator mutations in the mutS gene of Escherichia co" by Te-hui Wu and Martin G. Marinus
Genetic Complementation Test; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; MutS DNA Mismatch-Binding Protein; * ... Mutagenesis; Nalidixic Acid; Nucleic Acid Heteroduplexes; Plasmids; *Point Mutation; Recombination, Genetic; Rifampin; Sequence ...https://escholarship.umassmed.edu/oapubs/663/
OPUS at UTS: The VQ motif protein IKU1 regulates endosperm growth and seed size in Arabidopsis - Open Publications of UTS...
Genetic Complementation Test. en_US. dc.subject.mesh. Amino Acid Sequence. en_US. ...https://opus.lib.uts.edu.au/handle/10453/28222
OPUS at UTS: Chlamydia trachomatis responds to heat shock, penicillin induced persistence, and IFN-gamma persistence by...
Genetic Complementation Test. en_US. dc.subject.mesh. Heat-Shock Response. en_US. ...https://opus.lib.uts.edu.au/handle/10453/37047
Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus...
Genetic Complementation Test; Proteomics; Virulence; Gene Deletion; Amino Acid Sequence; Multigene Family; Molecular Sequence ...http://eprints.leedsbeckett.ac.uk/2387/
mediaTUM - Medien- und Publikationsserver
Genetic complementation tests using Pitx3 ( ak/+ ) mice confirmed eyl as a new allele of Pitx3 (Pitx3 ( eyl )). Sequencing of ... Genetic complementation tests using Pitx3 ( ak/+ ) mice confirmed eyl as a new allele of Pitx3 (Pitx3 ( eyl )). Sequencing of ...http://mediatum.ub.tum.de/1072936
Rmr6 Maintains Meiotic Inheritance of Paramutant States in Zea mays | Genetics
Genetic complementation tests between the ems97406 mutation and other mutations known to affect Pl′ were conducted using +/ ... Stock constructions and complementation tests:. Hand pollinations were used for all genetic crosses and detailed pedigree ... Genetic tests demonstrate that Rmr6 encodes a common component required for establishing paramutations at diverse maize loci. ... To test the role of Rmr6 in r1 paramutation, near isogenic R-r/R-r and R-st/R-st W22 lines were first pollinated by a single +/ ...http://www.genetics.org/content/171/2/725