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*  Similar papers for Von Hippel-Lindau tumour suppressor gene. Localization of expression by in situ hybridization. - Semantic...
The expression of the VHL gene was limited to the adult and fetal brain and kidney, and the adult prostate. Nerve cells in ... The present paper describes an in situ hybridization study to assess the function of the VHL gene in adult human tissues and in ... The distribution of VHL gene expression in the mouse embryo was recently studied by in situ hybridization, along with human VHL ... tumour suppressor gene is responsible not only for VHL disease, but also for sporadic renal cell carcinoma and cerebellar ...
https://www.semanticscholar.org/paper/Von-Hippel-Lindau-tumour-suppressor-gene-Localizat-Nagashima-Miyagi/530d0a039934405c671e043497e10e2b13361d65?tab=relatedPapers
*  The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth | JCB
The von Hippel-Lindau tumor suppressor gene and kidney cancer. Clin. Cancer Res. 10:6290S-6295S. ... Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat. Genet. 7:85-90. ... The tumor syndrome von Hippel-Lindau (VHL) disease is caused by heterozygous germline inactivation of the VHL tumor suppressor ... Tumour suppression by the human von Hippel-Lindau gene product. Nat. Med. 1:822-826. ...
http://jcb.rupress.org/content/175/4/547
*  Aberrant DNA methylation associated with Alzheimer's disease in the superior temporal gyrus
Functional analysis was performed to investigate the biological functions of the genes associated with differentially ... Further analysis examined 2,211 differentially methylated CpGs (covering 1,991 genes). AD subjects demonstrated distinctive DNA ... onset AD and 34 controls without dementia were recruited from the Gene Expression Omnibus database. Through systemic quality ... Hypermethylation was mainly detected for genes regulating the cell cycle progression, whereas hypomethylation was observed in ...
https://www.spandidos-publications.com/etm/15/1/103/abstract
*  Functional analysis of chromosome 18 in pancreatic cancer: strong evidence for new tumour suppressor genes.
... Domenii publicaţii ... This study was intended to provide functional evidence for the existence of new tumour suppressor gene(s) located on chromosome ... Cuvinte cheie: pancreatic cancer, tumour suppressor gene, loss of heterozygosity, chromosome 18q ... CONCLUSION: These data represent strong functional evidence that chromosome 18q encodes strong tumour and metastasis suppressor ...
http://ad-astra.ro/2005/03/28/functional-analysis-of-chromosome-18-in-pancreatic-cancer-strong-evidence-for-new-tumour-suppressor-genes/
*  Plus it
Physical mapping of chromosome 17p13.3 in the region of a putative tumor suppressor gene important in medulloblastoma. Genomics ... although candidate tumor suppressor genes at this locus, such as HIC-1, have yet to be clearly implicated in medulloblastoma ... loci for the PTCH and SUFU tumor suppressor genes, respectively, mutations of which sonic hedgehog pathway components have been ... than in classic tumors (11%), which is a significant difference (χ2 test, P = 0.034). In addition, all 4 of the tumors with ...
http://clincancerres.aacrjournals.org/content/10/16/5482
*  Nwts - National Wilms` Tumor Studies in Medical & Science by AcronymsAndSlang.com
The Medical & Science Acronym /Abbreviation/Slang Nwts means National Wilms` Tumor Studies. by AcronymAndSlang.com ... wt1 - Wilms' tumor suppressor 1. *wt1 - Wilms' tumor 1 gene. *WAGR - Wilms' tumor, aniridia, genital abnormalities and mental ... Other shorthands for National Wilms' Tumor Studies are: NWTS Nwts - National Wilms` Tumor Studies in Medical & Science by ... Nwts as abbreviation means "National Wilms' Tumor Studies". Q: A: What is shorthand of National Wilms' Tumor Studies?. The most ...
http://acronymsandslang.com/definition/5860516/Nwts-meaning.html
*  NDST4 Is a Novel Candidate Tumor Suppressor Gene at Chromosome 4q26 and Its Genetic Loss Predicts Adverse Prognosis in...
A novel candidate tumor suppressor gene, namely NDST4, was identified at 4q26. Gene expression of NDST4 was investigated in 52 ... Conclusions NDST4 gene is a novel candidate tumor suppressor gene in human cancer, and the loss of its function might be ... The study aimed to explore candidate tumor suppressor genes at chromosome 4q25-q28.2 and to delineate novel prognostic ... where NDST4 was the only gene that had markedly been downregulated in CRC tumors. By laser capture microdissection, NDST4 RNA ...
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067040
*  Von Hippel-Lindau tumor suppressor - Wikipedia
"Entrez Gene: VHL von Hippel-Lindau tumor suppressor". Czyzyk-Krzeska MF, Meller J (April 2004). "von Hippel-Lindau tumor ... The von Hippel-Lindau tumor suppressor also known as pVHL is a protein that in humans is encoded by the VHL gene. Mutations of ... Kaelin WG (September 2004). "The von Hippel-Lindau tumor suppressor gene and kidney cancer". Clinical Cancer Research. 10 (18 ... Kaelin WG (September 2004). "The von Hippel-Lindau tumor suppressor gene and kidney cancer". Clinical Cancer Research. 10 (18 ...
https://en.wikipedia.org/wiki/Von_Hippel%E2%80%93Lindau_tumor_suppressor
*  Oncogenes & Tumor Suppressor Genes - QIAGEN
Oncogenes and Tumor Suppressor Genes RT2 Profiler PCR Array The Rat Oncogenes & Tumor Suppressor Genes RT² Profiler PCR Array ... Tumor Suppressor Genes (TSG) EpiTect Methyl II PCR Array The Human Tumor Suppressor Genes EpiTect Methyl II Signature PCR Array ... Oncogenes and Tumor Suppressor Genes RT2 Profiler PCR Array The Human Oncogenes & Tumor Suppressor Genes RT² Profiler PCR Array ... Oncogenes and Tumor Suppressor Genes RT2 Profiler PCR Array The Mouse Oncogenes & Tumor Suppressor Genes RT² Profiler PCR Array ...
https://www.qiagen.com/be/shop/genes-and-pathways/complete-biology-list/oncogenes-and-tumor-suppressor-genes/
*  481044: p53 Tumor Suppressor Gene Protein,... | LabCorp
Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers. J Natl Cancer Inst. ... p53 Tumor Suppressor Gene Protein, Immunohistochemical, Paraffin Block. TEST: 481044 Test number copied ... Alterations of the p53 tumor suppressor gene have been shown to serve as an independent prognostic marker in a wide variety of ... Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J ...
https://www.labcorp.com/test-menu/32621/p53-tumor-suppressor-gene-protein-immunohistochemical-paraffin-block
*  Screening of Tumor Suppressor Genes in Metastatic Colorectal Cancer
... a tumor suppressor gene in advanced CRC and affect the development and metastasis of CRC by regulating 8 tumor suppressor genes ... Most tumor suppressor genes are commonly inactivated in the development of colorectal cancer (CRC). The activation of tumor ... Screening of Tumor Suppressor Genes in Metastatic Colorectal Cancer. Lu Qi1 and Yanqing Ding1,2 ... in accordance with the elevated expression of MBD1 mainly located on chromosomes 17p13 and 17p12 and 8 tumor suppressor genes ...
https://www.hindawi.com/journals/bmri/2017/2769140/abs/
*  How Tumor-Suppressor Gene p53 Keeps Cancer at Bay - Scientific American
Researchers have known for some time that the tumor-suppressor gene p53 plays a vital role in the body's struggle to stave off ... "In half of all tumor cells p53 is not working, sometimes because a kinase gene responsible for phosphorylation is mutated. When ... we might be able to restore p53 function in tumor cells with mutated kinase genes. We could give the compound to patients to ... The p53 gene monitors biochemical signals in cells that can indicate DNA damage or mutations. Upon detection of cancer ...
https://www.scientificamerican.com/article/how-tumor-suppressor-gene/
*  Tumor Suppressor Gene Located In Liver Cancer Cells | EurekAlert! Science News
... gene apparently plays an important role in the formation of liver cancer, according to researchers from the Duke University ... acts as a tumor suppressor gene in human liver tumors could help researchers develop an early diagnostic test for liver cancer ... Mice normally have only one active copy of this tumor suppressor gene rather than the two working copies humans possess. This ... A report on this tumor suppressor gene appears in the December issue of Nature Genetics. Along with principal investigator ...
https://eurekalert.org/pub_releases/1996-04/DU-TSGL-290496.php
*  Combination of Sequencing Techniques IDs Potential Tumor Suppressor Genes | GenomeWeb
It's a good way to strengthen the data because you can prioritize variants in genes that are affecting transcription.' ... Combination of Sequencing Techniques IDs Potential Tumor Suppressor Genes. Dec 07, 2010 ... which could ultimately aid in the search for tumor suppressor genes, according to a team of researchers from the J. Craig ... Gene-Based Diets Don't Help Weight Loss. A new study in JAMA finds that genetic tests might not be able to determine what diet ...
https://www.genomeweb.com/sequencing/combination-sequencing-techniques-ids-potential-tumor-suppressor-genes
*  Tumor Suppressor Genes | Springer for Research & Development
Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by ... Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, covers all known tumor suppressor genes, describing their ... the two volumes of Tumor Suppressor Genes provide an unparalleled compilation of key data on all known tumor suppressor ... Analysis of Gene Promoter Regulation by Tumor Suppressor Genes Kumaravel Somasundaram, Sanjeev Das, Smita Lakhotia, Narendra ...
https://rd.springer.com/book/10.1385/1592593291
*  Tumor Suppressor Genes - Volume 2: Regulation, Function, | Wafik S. El-Deiry | Springer
Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by ... Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, covers all known tumor suppressor genes, describing their ... the two volumes of Tumor Suppressor Genes provide an unparalleled compilation of key data on all known tumor suppressor ... Tumor Suppressor Genes. Book Subtitle. Volume 2: Regulation, Function, and Medicinal Applications. Editors. * Wafik S. El-Deiry ...
http://www.springer.com/us/book/9780896039872
*  Absent Tumor-Suppressor Genes Allow Metastatic Melanoma to Thwart Immunotherapy
It's what's missing in the tumor genome, not what's mutated, that thwarts treatment of metastatic melanoma with immune ... Absent Tumor-Suppressor Genes Allow Metastatic Melanoma to Thwart Immunotherapy. by Dr. Trupti Shirole on March 5, 2017 at 9:51 ... They found repeated loss of blocks of chromosomes six, 10 and 11, which harbor 13 known tumor-suppressing genes.. Analysis of a ... Absence of a variety of tumor-suppressing genes leads to resistance of metastatic melanoma treatment with both CTLA4 and PD1 ...
https://www.medindia.net/news/absent-tumor-suppressor-genes-allow-metastatic-melanoma-to-thwart-immunotherapy-168331-1.htm
*  A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions | PNAS
Cooperating chromosome 8p tumor suppressor genes. Wen Xue, Thomas Kitzing, Stephanie Roessler, Johannes Zuber, Alexander ... Cooperating chromosome 8p tumor suppressor genes. Wen Xue, Thomas Kitzing, Stephanie Roessler, Johannes Zuber, Alexander ... Early studies on the tumor-suppressor genes (TSGs) RB and TP53 suggested that such deletions can arise as a single mechanism ... A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions Message Subject (Your Name) has sent you a ...
https://www.pnas.org/content/109/21/8212.long
*  Tumor Suppressor Gene More Likely to Be Defective in Children with Autism
... Tumor Suppressor Gene More Likely to Be Defective in ... Tumor Suppressor Gene More Likely to Be Defective in Children with Autism. ... Higher p53 gene copy ratios and mtDNA deletions were more that twice as common in children with autism. Fathers of children ... The researchers say that the mtDNA deletions and altered p53 gene copy ratios seem to result from genetics in children with ...
https://www.niehs.nih.gov/research/supported/sep/2016/tumor-gene-defective/
*  Control of Retinal Development by Tumor Suppressor Genes | IntechOpen
... www.intechopen.com/embed/tumor-suppressor-genes/control-of-retinal-development-by-tumor-suppressor-genes' /,. Embed this code ... Control of Retinal Development by Tumor Suppressor Genes, Tumor Suppressor Genes Yue Cheng, IntechOpen, DOI: 10.5772/28870. ... Control of Retinal Development by Tumor Suppressor Genes, Tumor Suppressor Genes Yue Cheng, IntechOpen, DOI: 10.5772/28870. ... www.intechopen.com/embed/tumor-suppressor-genes/control-of-retinal-development-by-tumor-suppressor-genes' /, ...
https://www.intechopen.com/books/tumor-suppressor-genes/control-of-retinal-development-by-tumor-suppressor-genes/
*  Tumor Suppressor Gene is Silenced in Majority of Breast Cancers | EmaxHealth
Methylation leaves the gene unchanged but silences its activity by adding a brake onto the gene called a "methyl" group of ... Normal cells showed no methylation of this gene.. Finding even a few breast cells with methylated RARbeta2 is a potentially ... In addition to identifying at-risk women, the gene also provides a way to monitor whether various preventive agents are ... In addition to RARbeta2, Seewaldt's team is investigating other methylated genes to determine the extent of their role in the ...
https://www.emaxhealth.com/98/1910.html
*  MyoD Is a Tumor Suppressor Gene in Medulloblastoma | Cancer Research
Tumor and Stem Cell Biology MyoD Is a Tumor Suppressor Gene in Medulloblastoma. Joyoti Dey, Adrian M. Dubuc, Kyle D. Pedro, ... MyoD Is a Tumor Suppressor Gene in Medulloblastoma. Joyoti Dey, Adrian M. Dubuc, Kyle D. Pedro, Derek Thirstrup, Brig Mecham, ... MyoD Is a Tumor Suppressor Gene in Medulloblastoma. Joyoti Dey, Adrian M. Dubuc, Kyle D. Pedro, Derek Thirstrup, Brig Mecham, ... MyoD Is a Tumor Suppressor Gene in Medulloblastoma Message Subject (Your Name) has forwarded a page to you from Cancer Research ...
http://cancerres.aacrjournals.org/content/73/22/6828
*  Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis | PNAS
... in CNS glia cooperates with loss of the tumor suppressor loci Ink4a;Arf and PTEN gene products to form GBM tumors. ... Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Haihao Zhu, Jaime Acquaviva ... 2002) Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 32:148-149. ... Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis ...
http://www.pnas.org/content/106/8/2712
*  Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene | SpringerLink
The Apc gene product (APC), basically a cytoplasmic protein, blocks cell cycle ... gene is mutated in familial adenomatous polyposis and in sporadic colorectal tumors. ... Baeg GH, Matsumine A, Kuroda T et al. (1995) The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to ... Bhat RV, Baraban JM, Johnson RC, Eipper BA, Mains RE (1994) High levels of expression of the tumor suppressor gene APC during ...
https://link.springer.com/article/10.1111%2Fj.1447-073x.2005.00106.x
*  Oncogenes and Tumor Suppressor Genes - AMA Manual of Style
Oncogenes and Tumor Suppressor Genes Oncogenes and Tumor Suppressor Genes. Chapter:. (p. 529) Nomenclature. Author(s):. Harriet ... Human oncogenes should be expressed according to style for human gene symbols (see , Human Gene Nomenclature). Mouse oncogenes ... These genes exist widely outside the systems in which they were discovered, and their normal cellular homologues are important ... 15.6.2 Human Gene Nomenclature. *15.6.3 Oncogenes and Tumor Suppressor Genes ...
http://www.amamanualofstyle.com/view/10.1093/jama/9780195176339.001.0001/med-9780195176339-div2-418?rskey=rY0Hea&result=6&q=