Loading...
*  Cancer Immunotherapy? There's a Synthetic Gene Circuit for That | GEN
A synthetic biology approach that adds immunostimulatory gene circuits to cancer cells may contribute to combination ... Cancer Immunotherapy? There's a Synthetic Gene Circuit for That A synthetic biology approach that adds immunostimulatory gene ... The installation of synthetic gene circuits that work only in cancer cells represents a new form of cancer immunotherapy, which ... Lu and colleagues described their work October 19 in Cell, in an article entitled "Synthetic RNA-Based Immunomodulatory Gene ...
https://www.genengnews.com/gen-news-highlights/cancer-immunotherapy-theres-a-synthetic-gene-circuit-for-that/81255078
*  Weiss Laboratory for Synthetic Biology | MIT CSAIL
Synthetic gene networks will also enable a wide range of new programmed cells applications. We use computer engineering ... The construction of synthetic gene networks can help improve our understanding of such naturally existing regulatory functions ... We constructed synthetic gene networks that implement biochemical logic circuits in Escherichia coli fabricated using the AND, ... Weiss Laboratory for Synthetic Biology. Contact Us. The Weiss Lab seeks to create integrated biological systems capable of ...
https://www.csail.mit.edu/research/weiss-laboratory-synthetic-biology
*  COMPUTATIONAL METHODS FOR SYNTHETIC GENE DESIGN - Patent application
... preliminary optimized gene. ORFs not encoding the gene of interest were removed from the preliminary optimized gene by ... 1984) Gene 31:65-78; Khudyakov et al. (1993) Nucleic Acids Res. 21:2747-2754). [0019]A synthetic sequence includes a nucleotide ... Patent application title: COMPUTATIONAL METHODS FOR SYNTHETIC GENE DESIGN. Inventors: Daniel J. Tomso Agents: ALSTON & BIRD LLP ... Patent application title: COMPUTATIONAL METHODS FOR SYNTHETIC GENE DESIGN. Inventors: Daniel J. Tomso (Bahama, NC, US) ...
http://www.patentsencyclopedia.com/app/20090137409
*  Synthetic DNA Libraries - Gene Synthesis - GENEWIZ
Sequence files of the synthetic gene alone or subcloned into a vector ... Featured Synthetic DNA Libraries. 1. Alanine Scanning Library: Alanine scanning is a widely-used approach that involves ... SYNTHETIC DNA LIBRARIES. Researchers working in fields such as protein engineering, discovery biology, structural biology, ... synthetic biology, antibody engineering, and enzyme engineering choose GENEWIZ's Synthetic DNA Libraries because of our wide ...
https://www.genewiz.com/en/Public/Services/Gene-Synthesis/Synthetic-DNA-Libraries
*  Modulation of Gene Expression by Synthetic Nucleic Acids
Duplex RNAs complementary to promoter regions can repress or activate gene expression. ... Agents that activate expression of specific genes to probe cellular pathways or alleviate disease would go beyond existing ... Modulation of Gene Expression by Synthetic Nucleic Acids. Agents that activate expression of specific genes to probe cellular ... Duplex RNAs complementary to promoter regions can repress or activate gene expression. The mechanism of these promoter-directed ...
http://www.jbsdonline.com/modulation-gene-expression-synthetic-nucleic-acids-p17297.html
*  Isogenica Secure Funding from UK's Technology Strategy Board to Develop Gene Library Synthesis for Synthetic Biology | Business...
Cambridge UK and Imperial College London secure funding from UK's Technology Strategy Board to develop gene library synthesis ... Isogenica Secure Funding from UK's Technology Strategy Board to Develop Gene Library Synthesis for Synthetic Biology ... Synthetic Biology at Imperial College The Centre for Synthetic Biology and Innovation (CSynBI) at Imperial College was the ... optimise a gene library assembly technology for potential use in synthetic biology. ...
https://www.businesswire.com/news/home/20140630005499/en/Isogenica-Secure-Funding-UK%E2%80%99s-Technology-Strategy-Board
*  From bacterial gene expression decomposition to Synthetic Biology • Research - Institut Pasteur
From bacterial gene expression decomposition to Synthetic Biology. Matthieu Jules will talk about From bacterial gene ... Matthieu Jules will talk about From bacterial gene expression decomposition to Synthetic Biology ... expression decomposition to Synthetic Biology From bacterial gene expression decomposition to Synthetic Biology Registration ...
https://research.pasteur.fr/en/event/from-bacterial-gene-expression-decomposition-to-synthetic-biology/
*  Gene gymnastics : Synthetic biology for baculovirus expression vector system engineering
Recently, synthetic biology approaches have begun to make their mark in improving existing BEVS reagents by de novo design of ... comprising new custom designed reagents that further facilitate the integration of heterologous genes into the baculovirus ... to custom design and engineer the entire baculovirus genome for optimized production properties using a bottom-up synthetic ...
https://insights.ovid.com/bioeng/201309000/01768440-201309000-00002
*  Cloning of synthetic gene including antigens against Urinary Tract Infections in pET28a+ vector
Primers were designed by Gene Runner. Gene and pET28a+ vector was checked by SnappGene. Synthetic gene was multiplied by PCR ... The synthetic Gene which was designed against these three bacteria including antigens which are important and common to cause ... The aim of this study is cloning of synthetic gene include antigens against UTIs in pET28a+ vector. Antibiotic resistant has ... This gene has involved 1293bp. It was ordered to Gene Ray Biotechnology. ...
http://jphs.ir/article_535241.html
*  Synthetic genes can make weird new proteins that actually work - Aging Free - Longevity and Cryonics >...
The discovery may widen the toolkit of synthetic biologists trying to build bespoke organisms. ... Synthetic genes can make weird new proteins that actually work posted on 5/9/2017 5:08:00 PM ... coli bacteria that were missing a single gene (and hence, the protein it coded for). The missing genes Hecht tested were ones ... Categories: , Tags: Proteins, synthetic biology, genome modification, genetic engineering, genetics , Comments: (0) , View ...
http://agingfree.org/en-us/news/ArticleID/517/Synthetic-genes-can-make-weird-new-proteins-that-actually-work
*  Bimodal and hysteretic expression in mammalian cells from a synthetic gene circuit - May T.
Reference : Bimodal and hysteretic expression in mammalian cells from a synthetic gene circuit. ... Bimodal and hysteretic expression in mammalian cells from a synthetic gene circuit. ... A synthetic positive feedback loop, based on the Tetracycline regulation system was implemented in a lentiviral vector system ... This gene regulation circuit yields a bimodal expression response. Based on experimental data a mathematical model based on ...
http://orbilu.uni.lu/handle/10993/20315
*  Spatial-Stochastic modelling of synthetic gene regulatory networks<...
Spatial-Stochastic modelling of synthetic gene regulatory networks. Journal of Theoretical Biology. 2019 May 7;468:27-44. https ... Macnamara, CK, Mitchell, EI & Chaplain, MAJ 2019, 'Spatial-Stochastic modelling of synthetic gene regulatory networks' Journal ... Spatial-Stochastic modelling of synthetic gene regulatory networks. Cicely K. Macnamara, Elaine I. Mitchell, Mark A. J. ... Macnamara, C. K., Mitchell, E. I., & Chaplain, M. A. J. (2019). Spatial-Stochastic modelling of synthetic gene regulatory ...
https://discovery.dundee.ac.uk/en/publications/spatial-stochastic-modelling-of-synthetic-gene-regulatory-network
*  Engineering multi-input gene regulation for applications in Synthetic Biology
Synthetic biology offers insight into molecular biology through the design and implementation of synthetic gene networks. One ... This work also suggest strategies for the engineering of additional components for use in synthetic gene networks. ... That is, we develop methods for making the expression of a reporter gene dependent on two or more inputs in Escherichia coli. ... "Engineering multi-input gene regulation for applications in Synthetic Biology." (2015) Diss., Rice University. https://hdl. ...
https://scholarship.rice.edu/handle/1911/88123
*  SynTReN 1.2 - Generator of Synthetic Gene Expression data for Design and Analysis of Structure Learning algorithms
... is a network generator that creates synthetic transcriptional regulatory networks and produces simulated gene expression data ... Posted by admin at 5:24 pm Tagged with: Analysis, Design, Generator, Structure Learning, Synthetic Gene Expression, SynTReN 640 ... SynTReN 1.2 - Generator of Synthetic Gene Expression data for Design and Analysis of Structure Learning algorithms. System ... SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms.. Van den ...
http://www.mybiosoftware.com/syntren-1-2-generator-synthetic-gene-expression-data-design-analysis-structure-learning-algorithms.html
*  A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. | Sigma-Aldrich
A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor.. [Nicholas C Turner, Christopher J ... To discover new determinants of sensitivity to these drugs, we performed a PARP-inhibitor synthetic lethal short interfering ... These results highlight the potential of synthetic lethal siRNA screens with chemical inhibitors to define new determinants of ...
https://www.sigmaaldrich.com/catalog/papers/18388863
*  Gene Expression: A bold prediction: "synthetic associations" are not a panacea
Narrow Roads of Gene Land 1. Narrow Roads of Gene Land 2. Narrow Roads of Gene Land 3. Statistical Methods in Molecular ... Narrow Roads of Gene Land 1. Narrow Roads of Gene Land 2. Narrow Roads of Gene Land 3. Statistical Methods in Molecular ... A bold prediction: "synthetic associations" are not a panacea posted by p-ter @ 1/26/2010 08:48:00 PM A bold prediction: " ... The Math Gene. Explaining Culture. Origin and Evolution of Cultures. Dawn of Human Culture. The Origins of Virtue Prehistory of ...
http://www.gnxp.com/blog/2010/01/bold-prediction-synthetic-associations.php
*  Can terminators be used as insulators into yeast synthetic gene circuits? | Journal of Biological Engineering | Full Text
Hence, it seems preferable to avoid the insulation of non-weak promoters when building synthetic gene circuit in yeast S. ... In this way promoter leakage due to the read-through from an upstream gene or RNA polymerase unspecific binding to the DNA is, ... By placing different yeast terminators (natural and synthetic) in front of the CYC1 yeast constitutive promoter stripped of ... Gene. 1993; 131:129-34.View ArticleGoogle Scholar. *. Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. A synthetic gene ...
https://jbioleng.biomedcentral.com/articles/10.1186/s13036-016-0040-5
*  WO2013163346 SYNTHETIC PROMOTER FOR MODULATING GENE EXPRESSION
... an exogenous nucleic acid fragment encoding thymidine kinase is operably linked to the synthetic promoter which is then shown ... wherein the nucleic acid construct includes a synthetic promoter designed using selected PDX-1 activation sites such as those ... EN) SYNTHETIC PROMOTER FOR MODULATING GENE EXPRESSION. (FR) PROMOTEUR SYNTHÉTIQUE PERMETTANT DE MODULER L'EXPRESSION GÉNIQUE. ... an exogenous nucleic acid fragment encoding thymidine kinase is operably linked to the synthetic promoter which is then shown ...
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2013163346
*  KRIBB: Expression of human interleukin-2 from native and synthetic genes in E. coli : no correlation between major codon bias...
complementary dna; interleukin 2; synthetic dna; article; cloning vector; codon; escherichia coli; gene expression; genetic ... Expression of IL-2 from the cDNA and synthetic gene were estimated to be as right at 18% and 14%, respectively. No correlation ... Expression of human interleukin-2 from native and synthetic genes in E. coli : no correlation between major codon bias and high ... Expression of human IL-2 from the cDNA and synthetic gene was compared using the E. coli expression system. Expression plasmids ...
https://repository.kribb.re.kr/handle/201005/4356
*  PhD Studentship: Developing robust synthetic biology-enabled biosensors for Gene Therapy manufacture - Loughborough University ...
PhD Studentship: Developing robust synthetic biology-enabled biosensors for Gene Therapy manufacture. Loughborough University ...
http://www.jobs.ac.uk/job/ANS312
*  Gene Control, Synthetic Promoters | Cell and Gene Therapy & Medicines | Synpromics
... improves human health with effective cell and gene therapies using genomics, bioinformatics and bioprocessing. ... Cell and Gene Medicine. Patentable synthetic promoters for cell & gene medicine, enable specificity, enhanced therapeutic ... Synpromics enables unprecedented control of gene expression through its ability to custom design synthetic cell-type, or ... The leader in gene control. Improving human health by enabling safer, more effective cell and gene medicines through ...
http://www.synpromics.com
*  A mammalianized synthetic nitroreductase gene for high-level expression - pdf descargar
A mammalianized synthetic nitroreductase gene for high-level expression. . Biblioteca virtual para leer y descargar libros, ... The synthetic gene was investigated for its expression efficacy and ability to sensitize mammalian cells to CB1954 using ... A mammalianized synthetic nitroreductase gene for high-level expression - Descarga este documento en PDF. Documentación en PDF ... Therefore, we generated a synthetic variant of the nitroreductase gene, called ntro, adapted for high-level expression in ...
http://libros.duhnnae.com/2017/jul/149887717421-A-mammalianized-synthetic-nitroreductase-gene-for-high-level-expression.php
*  Synthetic Transcription Amplifier System for Orthogonal Control of Gene Expression in Saccharomyces cerevisiae
The system works as a fixed-gain transcription amplifier, where the input signal is transferred via a synthetic transcription ... modules for multiple genes with highly diversified expression levels ranging from negligible to very strong using one synthetic ... In contrast to most existing modular gene expression regulation systems, the present system is independent from externally ... factor (sTF) onto a synthetic promoter, containing a defined core promoter, generating a transcription output signal. The ...
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148320
*  ASMscience | Synthetic Riboswitches Turn On Bacterial Genes
Justin P. Gallivan's laboratory at Emory University, Atlanta, Ga., creates synthetic riboswitches that tune gene ... sequences of RNA that alter gene expression when they bind a small-molecule metabolite. ...
http://www.asmscience.org/content/journal/microbe/10.1128/microbe.6.35.1