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*  Cancer Immunotherapy? There's a Synthetic Gene Circuit for That | GEN
A synthetic biology approach that adds immunostimulatory gene circuits to cancer cells may contribute to combination ... Cancer Immunotherapy? There's a Synthetic Gene Circuit for That A synthetic biology approach that adds immunostimulatory gene ... The installation of synthetic gene circuits that work only in cancer cells represents a new form of cancer immunotherapy, which ... Lu and colleagues described their work October 19 in Cell, in an article entitled "Synthetic RNA-Based Immunomodulatory Gene ...
https://www.genengnews.com/gen-news-highlights/cancer-immunotherapy-theres-a-synthetic-gene-circuit-for-that/81255078
*  Precise and programmable biological circuits
To understand the underlying technology, it is important to know that these biological sensors consist of synthetic genes that ... The gene is activated via a special enzyme, a recombinase, which extracts the gene from the circuit DNA and reinstalls it in ... In the controllable biosensor developed by Lapique, the gene responsible for the output signal is not active in its basic state ... ETH doctoral candidate Nicolas Lapique from the group led by Yaakov Benenson, Professor of Synthetic Biology in the Department ...
http://www.innovations-report.com/html/reports/life-sciences/precise-and-programmable-biological-circuits.html
*  調査レポート | 合成生物学の世界市場:ツール(ゼノ核酸、シャーシ・オーガニズム、酵素等)、
Table 17 Synthetic Biology Market Size For Gene Synthesis, By Region, 2012-2018 ($Million) 64. Table 18 Synthetic Biology ... Figure 17 Increasing Demand For Synthetic Genes To Spur Market Growth 39. Figure 18 Porter'S Five Forces Analysis: Synthetic ... This has resulted in advanced production of synthetic genes and chassis to develop synthetic organisms from scratch. ... 8 Synthetic Biology Market, By Technology 58. 8.1 Introduction 59. 8.1.1 Enabling Technologies 61. 8.1.1.1 Gene Synthesis 63. ...
http://mkt.h-and-i.jp/marketsandmarkets-industry-158104-data
*  Biological Circuits for Synthetic Biology: Berkeley Lab Researchers Aim to Keep Things Simple | Berkeley Lab
... natural ability to sense small molecules and regulate genes has made the RNA molecule an important tool for synthetic biology ... Biological Circuits for Synthetic Biology: Berkeley Lab Researchers Aim to Keep Things Simple. Feature Story Lynn Yarris (510) ... Synthetic biology, however, is still a relatively new scientific field plagued with the trial and error inefficiencies that ... Synthetic biologists have been using RNA regulatory mechanisms to program genetic networks in cells to achieve specific results ...
http://newscenter.lbl.gov/2011/05/26/biological-circuits-for-synthetic-biology/
*  Groups Criticize Presidential Commission's Recommendations on Synthetic Biology | ETC Group
... and religious groups rejected the recommendations as a deeply flawed response to advances in synthetic biology, including the ... The Presidential Commission for the Study of Bioethical Issues released its recommendations on the oversight of synthetic ... creation this year of the first entirely synthetic organism, that demand strong federal oversight. ... "The President's Commission is relying on suicide genes as a way to 'contain' synthetic organisms but this technology cannot ...
http://www.etcgroup.org/content/groups-criticize-presidential-commission%E2%80%99s-recommendations-synthetic-biology
*  Synthetic chemistry and biology in new method for more efficient hydrogen gas production - Uppsala University, Sweden
"We can modify selected organisms genetically and insert the gene encoding the enzyme into more easily manageable bacteria, and ... Synthetic chemistry and biology in new method for more efficient hydrogen gas production Press release. 2017-05-03 ... They want to further improve the artificial enzymes at genetic level and also enhance the process by modifying the synthetic ... The article "In vivo activation of an [FeFe] hydrogenase using synthetic cofactors" was published in Energy and Environmental ...
http://www.uu.se/en/news-media/press-releases/press-release/?id=3826&area=3,8&typ=pm&lang=en
*  Genome Engineering and Synthetic Biology (3rd edition) | VIB Conference series
Putting the whole genome to work: microbial and protein evolution with novel compound genes created from native protein-coding ... Genome Engineering and Synthetic Biology are revolutionizing Life Sciences. Driven by advances in the CRISPR-toolbox for rapid ... The 1st and 2nd Genome Engineering and Synthetic Biology: Tools and Technologies meeting (GESB) in September 2013 and January ... TLA Technology for targeted complete sequencing & haplotyping of (CRISPR) gene editing events; expected and unexpected findings ...
https://vibconferences.be/event/genome-engineering-and-synthetic-biology-3rd-edition
*  synthetic gene
... Leman leman at leman.org Tue Oct 19 19:05:36 EST 1999 *Previous message: synthetic gene ... Previous message: synthetic gene *Next message: synthetic gene * Messages sorted by: [ date ] [ thread ] [ subject ] [ author ] ...
http://www.bio.net/bionet/mm/methods/1999-October/078790.html
*  SGDB | Show Synthetic Gene ID: 209
The synthetic gene was functionally expressed in both hosts S. cerevisiae and Pichia pastoris, and the effect of heterologous ... In particular, using P. pastoris cells, the synthetic gene was functionally overexpressed, allowing for the first time to ... The natural gene was codon optimized based on the codon usage of highly expressed genes in. Saccharomyces cerevisiae. ... the natural gene, lip1, was codon optimized based on the codon usage patterns of highly expressed genes in S. cerevisiae. lip1 ...
http://www.umbc.edu/codon/sgdb/show_records.php?rgid=209
*  SGDB | Show Synthetic Gene ID: 158
Codon-optimized genes were synthesized for the SIVmac239 Gag, a mutant Gag with mutations in the major homology region, and a ... Natural gene was not used in the experiment.. COntacted authors for the sequence on 1/23/06. ...
http://www.umbc.edu/codon/sgdb/show_records.php?rgid=158
*  Synthetic Gene Networks That Count | Science
Synthetic gene circuits have enlarged the molecular tool set available to bioengineers and molecular biologists (4, 12-24), and ... Synthetic gene networks can be constructed to emulate digital circuits and devices, giving one the ability to program and ... 1C). T7 RNAP is the gene at the first node driving transcription of T3 RNAP, which ultimately drives transcription of GFP. All ... Because the recombinase gene is inverted with respect to the upstream promoter, further expression of recombinase protein ...
http://science.sciencemag.org/content/324/5931/1199?ijkey=1b1833557b9df0fedab79d216c3af8eecfb2961c&keytype2=tf_ipsecsha
*  Synthetic genes can make weird new proteins that actually work | New Scientist
Synthetic genes can make weird new proteins that actually work. Life 3 May 2017 A dose of the right novel protein can aid ... coli bacteria that were missing a single gene (and hence, the protein it coded for). The missing genes Hecht tested were ones ... Eventually, synthetic biologists should be able to use Hecht's approach to find a wide range of novel proteins for their ... But for four of the 80 gene deletions Hecht worked on, at least one - and in one case, hundreds - of the semi-random novel ...
https://www.newscientist.com/article/2129752-synthetic-genes-can-make-weird-new-proteins-that-actually-work/
*  Synthetic Genes | Physics Forums - The Fusion of Science and Community
... to make synthetic genes and that those genes would be unique genes- she said they would be like plastic (because plastic ... you can just use it by using it as a synthetic man-made gene (Since you couldn't use it as a non-synthetic gene Since it ... you can just use it by using it as a synthetic man-made gene (Since you couldn't use it as a non-synthetic gene Since it ... But anyways so I thought you could actually do ANYTHING with genetic engineering since you could make synthetic genes (genes ...
https://www.physicsforums.com/threads/synthetic-genes.81086/
*  Mapping the environmental fitness landscape of a synthetic gene circuit. - PubMed - NCBI
... bistable synthetic gene circuit controlling the expression of a bifunctional antibiotic resistance gene in Saccharomyces ... Mapping the environmental fitness landscape of a synthetic gene circuit.. Nevozhay D1, Adams RM, Van Itallie E, Bennett MR, ... A) The positive feedback (PF) synthetic gene circuit and its functional schematic, consisting of the rtTA-MF transactivator ... The upward cellular current (IL→H) was defined as the fraction of cells leaving the L gene expression state per unit time, ...
https://www.ncbi.nlm.nih.gov/pubmed/22511863
*  Synthetic gene network restoring endogenous pituitary-thyroid feedback control in experimental Graves' disease | PNAS
B) The synthetic thyroid hormone-responsive gene switch (TSR) consists of a fusion protein, combining the ligand-binding domain ... Synthetic gene network restoring endogenous pituitary-thyroid feedback control in experimental Graves' disease. Pratik Saxena, ... A synthetic thyroid hormone-responsive mammalian gene switch interfacing with the hypothalamus-pituitary-thyroid axis. (A) At ... Synthetic gene networks have reached a level of sophistication where they can precisely program cellular behavior in response ...
http://www.pnas.org/content/113/5/1244
*  Codon optimization tool makes synthetic gene design easy
Custom gene synthesis. Ordering your cloned sequences as synthetic gene products and save valuable time and resources. ... The IDT Codon Optimization Tool simplifies designing synthetic genes and gBlocks® Gene Fragments for expression in a variety of ... Use the free IDT Codon Optimization Tool to simplify designing synthetic genes and gBlocks Gene Fragments for expression in a ... Instead of spending days designing and constructing your synthetic gene, use the Codon Optimization Tool to order your gene in ...
https://www.idtdna.com/pages/education/decoded/article/codon-optimization-tool-makes-synthetic-gene-design-easy
*  Quantifying synthetic gene transcription in plants - LEGUME LABORATORY | PLOS Synthetic Biology Community
Quantitative Characterization of Genetic Parts and Circuits for Plant Synthetic Biology', was published online in Nature ... Quantifying synthetic gene transcription in plants - LEGUME LABORATORY Posted November 2, 2016 by Daniela Quaglia in From the ... For the full blog post visit: From the Community: Quantifying synthetic gene transcription in plants, LEGUME LABORATORY ... communication Space startup biotech student synbio synbiobeta synthetic biology synthetic biology and regulation Synthetic ...
https://blogs.plos.org/synbio/2016/11/02/quantifying-synthetic-gene-transcription-in-plants-legume-laboratory/
*  Synthetic gene database - Wikipedia
Synthetic gene database (SGDB) is a database of artificially engineered genes. Gene Wu, Gang; Zheng Yuanpu; Qureshi Imran; Zin ... a database of synthetic genes re-designed for optimizing protein over-expression". Nucleic Acids Res. England. 35 (Database ...
https://en.wikipedia.org/wiki/Synthetic_gene_database
*  Rapid, low-cost detection of Zika virus using paper-based synthetic gene networks
Further reports about: , RNA , Zika virus , blood sugar , healthcare systems , synthetic biology , synthetic gene networks ... RNA »Zika virus »blood sugar »healthcare systems »synthetic biology »synthetic gene networks ... Rapid, low-cost detection of Zika virus using paper-based synthetic gene networks. 09.05.2016 ... paper-based platform that can host synthetic gene networks for use outside of the lab. ...
http://www.innovations-report.com/html/reports/medicine-health/rapid-low-cost-detection-of-zika-virus-using-paper-based-synthetic-gene-networks.html
*  Iterative plug-and-play methodology for constructing and modifying synthetic gene networks.
... construction and modification of synthetic gene networks. This method emphasizes post-assembly modification of constructs based ... Constructing synthetic gene networks using this cloning process is straightforward (Fig. 1b). Components are each assigned to a ... 1a, Supplementary Table 2), based on common usage in previously published Escherichia coli synthetic gene networks. We then ... Synthetic biology: applications come of ageNat Rev GenetYear: 20101136737920395970. 6. Khalil AS,et al. A synthetic biology ...
http://www.biomedsearch.com/nih/Iterative-plug-play-methodology-constructing/23042452.html
*  What is the standard delivery vector IDT uses for Genes and MiniGene™ Synthetic Genes?
Synthetic Genes? In order to optimize manufacturing and delivery time, synthetic genes ≤5 kb in length will be provided in a " ... Your high-quality, synthetic gene can then be subcloned into the vector of your choice using a variety of methods. For more ... What is the standard delivery vector IDT uses for Genes and MiniGene™ ...
https://www.idtdna.com/pages/support/faqs/what-is-the-standard-delivery-vector-idt-uses-for-genes-and-mini-gene-synthetic-genes-
*  Biology | Free Full-Text | Expression of a Synthetic Gene for the Major Cytotoxin (Cyt1Aa) of Bacillus thuringiensis subsp....
We also expressed the chloroplast cyt1Aa gene in a wild-type Chlamydomonas strain (21 gr) that can grow on nitrate. These ... Expression of a Synthetic Gene for the Major Cytotoxin (Cyt1Aa) of Bacillus thuringiensis subsp. israelensis in the Chloroplast ... Expression of a Synthetic Gene for the Major Cytotoxin (Cyt1Aa) of Bacillus thuringiensis subsp. israelensis in the Chloroplast ... "Expression of a Synthetic Gene for the Major Cytotoxin (Cyt1Aa) of Bacillus thuringiensis subsp. israelensis in the Chloroplast ...
http://www.mdpi.com/2079-7737/7/2/29
*  Scientists Create Rapid, Low-Cost Detection of Zika Virus Using Paper-Based Synthetic Gene Networks | Infection Control Today
Scientists Create Rapid, Low-Cost Detection of Zika Virus Using Paper-Based Synthetic Gene Networks. May 06, 2016 ... paper-based platform that can host synthetic gene networks for use outside of the lab. ... "Our synthetic biology pipeline for rapid sensor design and prototyping has tremendous potential for application for the Zika ...
https://www.infectioncontroltoday.com/diagnostics/scientists-create-rapid-low-cost-detection-zika-virus-using-paper-based-synthetic-gene
*  A synthetic gene network architecture that propagates
Synthetic biology is a field that is tending towards maturity. Synthetic gene networks are becoming increasingly more complex, ... We also designed a synthetic gene network that can propagate signals across a population ofisogenic bacteria. We used the Plug- ... To this end, we present a synthetic gene network assembly strategy that emphasizes characterization-driven iteration. The Plug ... As complex as circuits become, it is still a difficult process to build a functional gene network. Much work has been done to ...
https://open.bu.edu/handle/2144/10923