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*  Gentaur Molecular :EIAab \ ELISA kit Class I histocompatibility antigen-like protein,Major histocompatibility complex class I...
Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus \ ... ELISA kit Class I histocompatibility antigen-like protein, ... MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus ... Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus mus ... Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus ...
http://www.antibody-antibodies.com/product2768734-search-ELISA_kit__Class_I_histocompatibility_antigen_like_protein,Major_histocompatibility_complex_class_I_related_gene_protein,MHC_class_I_related_gene_protein,Mouse,Mr1,Mr1a,Mus_musculus.html
*  HLA-DRB1 - HLA class II histocompatibility antigen, DRB1-13 beta chain precursor - Homo sapiens (Human) - HLA-DRB1 gene &...
To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta ... HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to ... In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. Primary dendritic cells (DCs) ... In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and ...
http://www.uniprot.org/uniprot/Q5Y7A7
*  Anti Mouse MHC Class I H-2Kb Antibody, clone AF6-88.5 - Mouse Anti-Mouse Monoclonal Antibody IHC-F, FC, IP - Buy Now! |Abgent
Anti Mouse MHC Class I H-2Kb Antibody, clone AF6-88.5 , Mouse Anti-Mouse Monoclonal Antibody validated in IHC-F, FC, IP ( ... MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the ... There are 3 major MHC class I proteins encoded by the H-2 which are H-2K, H-2L and H-2D. The H- 2K gene is part of the murine H ... Anti Mouse MHC Class I H-2Kb Antibody, clone AF6-88.5 is for research use only and not for use in diagnostic or therapeutic ...
http://www.abgent.com/products/ABD12625-Anti-Mouse-MHC-Class-I-H-2Kb-Antibody-clone-AF6-885-
*  Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells...
MHC, major histocompatibility complex; MICA, MHC class I-related chain A; mRNA, messenger RNA; NK, natural killer cell; PBS, ... We next transfected expression vectors of Myc-tagged MICA gene (pMyc-MICA), Myc-tagged MICA gene with mutation at ADAM9 ... In control HepG2 cells, in addition to full-length MICA, two bands with molecular weights of 39 kD and 37 kD were detected (Fig ... Major histocompatibility complex (MHC) class I-related chain A (MICA) is a ligand for NK group 2, member D (NKG2D) receptors ...
http://onlinelibrary.wiley.com/doi/10.1002/hep.23456/full
*  Defective Ribosomal Products Are the Major Source of Antigenic Peptides Endogenously Generated from Influenza A Virus...
Transience of MHC class I-restricted antigen presentation after influenza A virus infection. Proc. Natl. Acad. Sci. USA 106: ... After a 30 min Ab labeling at 4°C, cells were washed in excess PBS and analyzed by flow cytometry using a BD LSR II flow ... generation of defined peptide class I complexes has been limited to studies of recombinant vaccinia viruses expressing genes ... Rapid shutoff of Ag presentation after the addition of MHC class I Ag presentation inhibitors. A, L-Kb cells were infected with ...
http://www.jimmunol.org/content/184/3/1419.long
*  HLA class II histocompatibility antigen, DRB1-8 beta chain
To produce a MHC class II molecule that presents an antigen; three MHC class II molecules (heterodimers of an alpha and a beta ... ANALYSIS OF HLA II GENES IN RELATION TO ATOPIC AND NONATOPIC ASTHMA IN AN UZBEK POPULATION].. ... HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to ... HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) ...
https://pharos.nih.gov/idg/targets/Q30134
*  Frontiers | Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally...
... to a comparative study of melanoma patients treated with moDCs pulsed with both MHC class I and class II epitopes or MHC class ... Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther (2006) 13(10 ... which are subsequently degraded by the proteasome and presented on MHC class I molecules (86). Adding an MHC class II targeting ... This trend was reflected in the clinical response, as patients of the MHC class I/II arm showed increased progression free and ...
https://www.frontiersin.org/articles/10.3389/fimmu.2014.00165/full
*  Human Gene HLA-DMB (uc011hfk.2) Description and Page Index
Homo sapiens MHC class II antigen (HLA-DMB) mRNA, complete cds.. AB362554 - Homo sapiens HLA-DMB mRNA for MHC class II antigen ... DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated ... RefSeq Summary (NM_002118): HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer ... class II, DM beta precursor variant protein.. BC027175 - Homo sapiens major histocompatibility complex, class II, DM beta, mRNA ...
http://rohsdb.cmb.usc.edu/GBshape/cgi-bin/hgGene?hgg_gene=uc011hfk.2&hgg_prot=B0S7U8&hgg_chrom=chr6_mann_hap4&hgg_start=4359616&hgg_end=4362444&hgg_type=knownGene&db=hg19&hgsid=1289098_rEYyzmWZ9Xw4hhMOGbGzlYRwArae
*  MHC class I - Wikipedia
... though sometimes this process results in two new genes with divergent function.[16] It is likely that human MHC class Ib loci ( ... MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC ... Birth-and-death of MHC class I genes[edit]. Birth-and-death evolution asserts that gene duplication events cause the genome to ... MHC class I molecules are heterodimers that consist of two polypeptide chains, α and β2-microglobulin (b2m). The two chains are ...
https://en.wikipedia.org/wiki/MHC_class_I
*  Toxins | Free Full-Text | MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus...
Here, we investigated the relative contribution of MHC class II versus non-MHC class II genes in the humoral response to PA and ... Conversely, the humoral fine specificity of reactivity to LF appeared to be controlled primarily through non-MHC class II genes ... H-2k at the MHC class II locus), B6 (H-2b), and B6.H2k (H-2k). IgG antibody titers to LF were controlled primarily by the MHC ... class II locus, whereas IgG titers to PA were strongly influenced by the non-MHC class II genetic background. ...
http://www.mdpi.com/2072-6651/4/12/1451
*  Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel. | Sigma-Aldrich
Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel.. [Donald C ... We characterized two Mhc class II B loci in Leach's storm-petrel, Oceanodroma leucorhoa, focusing on exon 2 which encodes the ... Unlike many studies of duplicated Mhc genes, alleles of the two loci clustered into monophyletic groups. Consistent with this ... Overall, the results suggest that the gene duplication event leading to these two loci is not recent and that point mutations ...
https://www.sigmaaldrich.com/catalog/papers/25416539
*  The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin...
MHC class II (MHC-II) genes encode cell-surface glycoproteins that present antigens to CD4 T cells to initiate and control ... Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte ... Interactions with XL9 were dependent on active transcription of MHC-II genes and the presence of the MHC-II-specific ... To ascertain the relationship between MHC-II gene transcription and XL9, B lymphocyte cell lines, which are MHC-II negative ...
http://jem.rupress.org/content/205/4/785
*  Publication - Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.
The MHC class II gene Aa was disrupted by targeted mutation in embryonic stem (ES) cells derived from C57BL/6 mice to prevent ... Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.. Kontgen, F; Suss, G; Stewart, C; Steinmetz, M; Bluethmann, H ... The B6-Aa0/Aa0 mutant mice described in this study represent an important tool to investigate the involvement of MHC class II ... The complete lack of cell surface expression of MHC class II molecules in B6-Aa0/Aa0 homozygous mutant mice was directly ...
https://www.ozgene.com/publication/papers?view=publication&task=show&id=2
*  HLA-DRB1 - MHC class II antigen - Homo sapiens (Human) - HLA-DRB1 gene & protein
IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. ... IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. ... MHC class II antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>, ... tr,F4YZW3,F4YZW3_HUMAN MHC class II antigen (Fragment) OS=Homo sapiens OX=9606 GN=HLA-DRB1 PE=4 SV=1 ...
http://www.uniprot.org/uniprot/F4YZW3
*  HLA-DPB1 - MHC class II antigen - Homo sapiens (Human) - HLA-DPB1 gene & protein
IPR011162 MHC_I/II-like_Ag-recog. IPR014745 MHC_II_a/b_N. IPR000353 MHC_II_b_N. ... IPR011162 MHC_I/II-like_Ag-recog. IPR014745 MHC_II_a/b_N. IPR000353 MHC_II_b_N. ... PF00969 MHC_II_beta, 1 hit. ProDomi. View protein in ProDom or Entries sharing at least one domain. PD000328 MHC_II_b_N, 1 ... MHC class II antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>, ...
https://www.uniprot.org/uniprot/A0A077YED4
*  Polymorphism in MHC class II transactivator gene is not associated with susceptibility to colorectal cancer in Swedish patients.
Polymorphism in MHC class II transactivator gene is not associated with susceptibility to colorectal cancer in Swedish patients ... Adult, Aged, Aged; 80 and over, Case-Control Studies, Colorectal Neoplasms/*genetics, Female, Gene Frequency, Genetic ...
http://hj.diva-portal.org/smash/record.jsf?pid=diva2:36723
*  Regulation of MHC Class II Genes - Jeremy Boss
MHC-II genes are expressed in a tissue-specific manner and are regulated both developmentally and by the actions of immune ... interact directly with active MHC-II promoters that have the MHC-II master regulator CIITA bound. MHC-II gene transcription and ... 2012) CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments. Genes ... Proper regulation of the MHC-II genes is central to a healthy and active immune system as MHC-II proteins present processed ...
http://grantome.com/grant/NIH/R01-GM047310-19
*  Characterisation of MHC class II DRB genes in the northern tree shrew (Tupaia belangeri)
... * Home ... Characterisation of MHC class II DRB genes in the northern tree shrew (Tupaia belangeri). In: Immunogenetics. 62(9), pp. 613- ... Characterisation of MHC class II DRB genes in the northern tree shrew (Tupaia belangeri). Publikationstyp:. ... article{Oppelt2010Chara-13572, title={Characterisation of MHC class II DRB genes in the northern tree shrew (Tupaia belangeri ...
https://kops.uni-konstanz.de/handle/123456789/13572
*  Functional significance of polymorphism among MHC class II gene promoters. | IRIS Verona
Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic ... Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic ... Differential expression of major histocompatibility complex class II genes on murine macrophages associated with T cell ... Differential expression of major histocompatibility complex class II genes on murine macrophages associated with T cell ...
https://iris.univr.it/handle/11562/234879
*  New data from basal Australian songbird lineages show that complex structure of MHC class II β genes has early evolutionary...
We identified 177 alleles of the MHC class II β exon 2 in seven basal passerine species, with variation in numbers of alleles ... Phylogenetic reconstruction of avian lineages based on MHC class II β exon 2 sequences strongly supported the monophyletic ... Although the function of MHC genes appears to be conserved across taxa, there is great variation in the number and organisation ... with strong similarities to the MHC described in more derived passerine lineages rather than the simpler MHC in non-passerine ...
https://0-bmcevolbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12862-016-0681-5
*  MHC Class IIB Exon 2 Polymorphism in the Grey Partridge (Perdix perdix) Is Shaped by Selection, Recombination and Gene...
... is the chicken MHC. Although the number of studies on MHC in free-ranging species is increasing, the knowledge on MHC variation ... MHC Class IIB Exon 2 Polymorphism in the Grey Partridge (Perdix perdix) Is Shaped by Selection, Recombination and Gene ... Recombination and gene conversion appear to be involved in generating MHCIIB diversity in the Grey partridge; two recombination ... Here we describe the variation of MHC class IIB (MHCIIB) exon 2 in a population of the Grey partridge (Perdix perdix), a ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:664226
*  HLA among Brazilian patients with spontaneous chronic urticaria and positive autologous serum skin test
Keywords: Genes, MHC class I; Genes, MHC class II; HLA antigens; Skin tests; Urticaria ... Palavras-chave: Antígenos HLA; Genes Classe I do Complexo de Histocompatibilidade (MHC); Genes Classe II do Complexo de ... MHC class II antigen expression is increased in different forms of urticária. Int Arch Allergy Immunol. 1996;109:177-82. [ ... Is there any relationship between human leucocyte antigen class II and chronic urticaria? (Chronic urticaria and HLA class II ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400010&lng=en&nrm=iso
*  Cloning of major histocompatibility complex (Mhc) genes from threespine stickleback, Gasterosteus aculeatus. - Semantic Scholar
In the present study, both class I and class II B Mhc genes have been identified and sequenced. Fifteen distinct class I exon 2 ... The 12 distinct class II B sequences may be derived from six loci, which are, however, closely related to one another in both ... Such markers can be provided by the major histocompatibility complex (Mhc) genes, which are well known for their extensive ... with one family divided further into two subfamilies) derived from different ancestral genes. The ancestors presumably diverged ...
https://www.semanticscholar.org/paper/Cloning-of-major-histocompatibility-complex-%28Mhc%29-Sato-Figueroa/0dd7b67197394ab02f544ee83e2a483fecf1b668
*  Two different primate species express an identical functional MHC class I allele - Semantic Scholar
... expressed an MHC class I allele (Sage-G * 01) that was identical in coding sequence to an MHC class I allele (Saoe-G * 08) ... Here we show that an identical functional MHC class I molecule is present in two different primate species with an approximate ... While similar alleles have been found in closely related species, sharing of a functional MHC class I allele between two ... These data provide the first evidence that functional MHC class I molecules can be maintained entirely intact in two separate ...
https://www.semanticscholar.org/paper/Two-different-primate-species-express-an-identical-Evans-Piekarczyk/6382b232ef652699c3af953806954fff0c607d45
*  Mitchison NA[au] - PubMed - NCBI
Functional significance of polymorphism among MHC class II gene promoters.. Guardiola J, Maffei A, Lauster R, Mitchison NA, ... The distribution of variation in regulatory gene segments, as present in MHC class II promoters. ... with special reference to immunodeficiency and promoter polymorphism in class II MHC genes. ... Genetic variation in the MHC II promoter: lessons for regulation and for comparative genomics. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Mitchison+NA%5Bau%5D&dispmax=50