Antigen mimicry as an effective strategy to induce CSPG4-targeted immunity in dogs with oral melanoma: a veterinary trial |...
Gene ID: 1464)29 were ligated to the last 3187 bp of the Do-CSPG4 sequence (Gene ID: 487658). The hybrid HuDo-CSPG4 ... A better immune reaction to ErbB-2 tumors is elicited in mice by DNA vaccines encoding rat/human chimeric proteins. Cancer Res ... Gene expression profiling using nanostring digital RNA counting to identify potential target antigens for melanoma ... Genes 2019;10. doi:doi:10.3390/genes10070501. [Epub ahead of print: 30 06 2019].pmid:http://www.ncbi.nlm.nih.gov/pubmed/ ...
Boston Red Sox v Philadelphia Phillies - Spring Training Box Score - Wednesday, March 7, 2001
IP H R ER BB SO HR BOSTON WAKEFIELD 3 1 0 0 2 1 0 PICHARDO 1 3 1 1 0 1 0 SCHOUREK 1 1 1 1 0 0 1 B WARD 1 1 0 0 1 0 0 C CASTILLO ... Gene Schall walked, loading thebases. Johnny Estrada grounded into a double play, scoring Michaels, 9-8. Pinch hitter Reggie ... BOSTON AB R H BI PHILADELPHIA AB R H BI STYNES 3B 5 3 2 0 GLANVILLE CF 3 0 0 0 OFFERMAN 2B 2 1 0 0 DUCEY LF 2 1 1 0 NEILL RF 1 ... DP--BOSTON 2, PHILADELPHIA 1. LOB--BOSTON 4, PHILADELPHIA 8. 2B--STYNES, LIEBERTHAL, TO PEREZ, DUCEY. HR--VARITEK (OFF WOLF), ...
Daphne Branham - Research output - Research Profiles at Washington University School of Medicine
ErbB Receptors 100% * Non-Small Cell Lung Carcinoma 93% * Neoplasm Metastasis 64% ... Clark, S. W., Taylor, J., Wang, D. L., Abramson, J. S. & Batchelor, T. T., Jul 2 2013, In: Neurology. 81, 1, p. 93-94 2 p.. ... 1509-1510 2 p.. Research output: Contribution to journal › Article › peer-review ...
病理學科 - 研究成果 - 臺北醫學大學
Kao, Y. C. & Lee, J. C., 3月 2021, 於: Genes Chromosomes and Cancer. 60, 3, p. 180-189 10 p.. 研究成果: 雜誌貢獻 › 回顧型文獻 › 同行評審 ... Superficial ALK-rearranged myxoid spindle cell neoplasm with a novel FMR1-ALK fusion gene. Kao, Y. C., Lee, P. H., Wu, C. L., ... Genes and Diseases. 9, 6, p. 1408-1411 4 p.. 研究成果: 雜誌貢獻 › 文章 › 同行評審 ... Molecular Characterization of Dermatofibrosarcoma Protuberans The Clinicopathologic
Integrated analysis of breast cancer cell lines reveals unique signaling pathways | Genome Biology | Full Text
In addition, the ErbB receptors integrate a diverse array of signals, both at the cell surface level and through cross-talk ... We considered genes and proteins that are differentially expressed across the cell lines to be present in some cell lines and ... Gene expression values were centered by subtracting the mean value of each probe set across the cell line set from each ... First, for each gene or protein, we used PAM clustering and a mean split silhouette (MSS) statistic to determine whether the ...
September | 2013 | PLA2 Signaling
Attached genes were ECM relevant genes EFEMP2, the cytoskeletal proteins zyxin and nebulette, FAM107A and rhophilin, and the ... We made a decision to check cell lines from different cells and the ErbB independent SK Deborah MC cell line as a negative ... connected genes were the cytoskeletal proteins zyxin and neb. Posted on September 26, 2013. by plas9821 ... This statement is further supported from the homozygous deletion of catenin alpha-1 in PC 3M and PC 3, a gene that cooperates ...
discst-rna-seq | RNA-Seq Blog
These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009) ... Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular ... Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in a haploid in vitro cell model ... Methylation-mediated silencing of ATF3 promotes thyroid cancer progression by regulating prognostic genes in the MAPK and PI3K/ ...
Transcription Factors
Significantly, we also showed that sGC inhibitor treatment repressed tumor development in gene D-(-)-Quinic acid fusion. gene ... is definitely a member of the EGFR/ErbB/HER family of type I transmembrane tyrosine kinase receptors [11,12]. Large ... gene fused towards the exon 4 of (V-Ets Erythroblastosis Trojan E26 Oncogene Like) gene, leading to the overexpression of ... out of this 71-gene subset weve then identified several five ERG-regulated genes whose appearance levels are medically ...
KinMutBase: Structure resources
Gene. Name of gene. Protein Data Bank entries in GeneLynx. Available relevant model in PDB. Theoretical model produced by CBS ... Receptor protein-tyrosine kinase ERBB-2. Available. None. Available. FGFR1. Basic fibroblast growth factor receptor 1. ... Fibroblast growth factor receptor 2. Available. Tyrosine kinase domain:1GJO.pdb. Available. ... 5-AMP-activated protein kinase, catalytic alpha-2 chain. None. None. Available. ...
Human Anti-EGFR Recombinant Antibody (clone MIL27-3) - Creative Biolabs
Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral ... V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian) ... Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; ... Figure 2 IF staining of human cell line U-251 MG. (Immunofluorescent staining of human cell line U-251 MG shows localization to ...
OUH - Group members
C-erbB-2/HER-2 protein in human intracranial tumours. Eur J Cancer, 29A (11), 1604-6. DOI 10.1016/0959-8049(93)90305-y, PubMed ... Amplification of the epidermal growth factor receptor gene in human gliomas. Anticancer Res, 11 (6), 2095-8. PubMed 1776845 ... Expression of the epidermal growth factor receptor gene in human brain metastases. APMIS, 100 (8), 713-9. DOI 10.1111/j.1699- ... Overexpression of the epidermal growth factor receptor gene in a human carcinoma cell line, derived from a brain metastasis. J ...
Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress...
... a cell cycle gene that promotes cellular replication by mediating cell cycle checkpoint escape. This study identifies a novel ... which often harbor mutations in cell cycle checkpoint genes, particularly in TP53. Using a genetically engineered mouse model, ... PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis. J ... 6A), included several characterized genes (Fzd1, Akap9), as well as cell-cycle-associated genes (Dbf4, Cdk6, Cdk14) (Additional ...
Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3 | PLOS ONE
... have been shown to function as co-transcriptional activators for various cancer-promoting genes. However, the regions of each ... 2007) A five-gene signature and clinical outcome in non-small-cell lung cancer. The New England journal of medicine 356: 11-20 ... The ErbB/HER family of receptor tyrosine kinases (RTKs) consists of four family members: the epidermal growth factor receptor ( ... Mapp AK, Ansari AZ (2007) A TAD further: Exogenous control of gene activation. Acs Chemical Biology 2: 62-75. * View Article ...
Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart | Development | The Company of...
... coli lacZ gene inserted in-frame downstream of the first exon of the mouse Egfr gene(Sibilia and Wagner, 1995). In control ... The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. ... The lacZ gene was removed and replaced by a multiple cloning site. A loxP-flanked human EGFR(hEGFR) cDNA was inserted into the ... 3I)(Sibilia et al., 1998). Southern blot analysis confirmed the absence of the Egfr gene in hEGFRKI/KI GFAP-cre astrocytes(Fig ...
EGFR (K728A T790M C797S L858R), Active (E10-122Q2G) - SignalChem Online Store
Gene Aliases :ERBB, mENA, ERBB1, HER1. Scientific Background :EGFR is the receptor for members of the EGF family and is a ... 2. Kobayashi S, et al: EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. New Eng. J. Med. 352: 786-792, ... 2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell ...
EGFR Mutant (A767 S768insTLA) Protein(E10-13CG) - SignalChem Online Store
Gene Aliases :ERBB, mENA, ERBB1, HER1. Scientific Background :EGFR is the receptor for members of the EGF family and is a ... 2. Kobayashi S, et al: EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. New Eng. J. Med. 352: 786-792, ... 2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell ...
Plus it
2007) BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiol Dis 26:134-145. ... a ligand for members of the ErbB family of receptor-tyrosine kinases. This signaling pathway has numerous roles in the CNS, ... 2001) De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy. Am J Hum Genet 68:1327- ... 1998) Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B. Nat ...
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2...
Amplification of PDGFA gene and EGFR gene was detected in 7 tumor foci (Table S3). It should be mentioned that PDGFA was a ... DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling. PLoS One. 2018;13:e0198364 ... F) Gene enrichment of significantly changed mRNA in mGBM1_A compared with the other two tumor foci in mGBM2. G) Gene enrichment ... B) Gene enrichment of significantly changed mRNA in mGBM1_C compared with the other three tumor foci in mGBM1. C) Gene ...
Image Series List :: Spinal Cord
In silico Analysis of Possible Novel RNA Interactions and Deleterious Single Nucleotide Polymorphisms Related to MSX2, SHH,...
We also identified various SNPs in the investigated genes that changed the normal structure and thus the function of their ... Moreover, the hsa-miR-134-5p regulated the SHH and TFAP2A gene expression. LINC02035 and C3orf35 were also introduced as ... After pathway enrichment and gene ontology analysis, the protein-protein, microRNA (miRNA)-mRNA, and miRNA-long noncoding RNA ( ... Moreover, the potential deleterious SNPs in the selected genes were identified and finally, their validation and implications ...
1 - Teknik forex ajaib
ErbB-2HER-2Neu (ErbB-2) - An In Vivo Substrate of Ahaib cPAcP is implicated to be the major PTP in non-cancerous prostate ... The role of the putative tumor suppressor gene LGI1 in teknik forex ajaib pathogenesis of human ofrex remains poorly understood ... Endogenous type D Retrovirus in a marsupial, the common brushtail possum (Trichosurus vulpe- cula). targeting genes; Liu L et ... that describes how alleles or genes behave in an ideal population. ...
PANNELLINI, TANIA
The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis. 2010 Casorelli ... Stat3 is required for anchorage-independent growth and metastasis but not for mammary tumor development downstream of the ErbB- ... The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.. ... Stat3 is required for anchorage-independent growth and metastasis but not for mammary tumor development downstream of the ErbB- ...
YRC Public Data Repository - Protein Overview - MPK20 ARATH
ErbB-3 class receptor binding. 1.34841233233438. bayes_pls_golite062009. *ErbB-2 class receptor binding ... Gene Ontology predictions. 1. Term. Confidence. Notes. *acetylcholine receptor activator activity. 5.9159846946654. bayes_pls_ ... 2. View Details. [370..606]. deduced N/A No confident structure predictions are available. ... Mitogen-activated protein kinase 20 OS=Arabidopsis thaliana GN=MPK20 PE=1 SV=2 [Swiss-Prot] ...
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Browse Products by Cat. No. (3300 - 3399) | Tocris Bioscience
Genome-wide effects of social status on DNA methylation in the brain of a cichlid fish, Astatotilapia burtoni | BMC Genomics |...
... and DMRs could affect gene expression in multiple ways. DMR genes were more likely to be transcription factors, have a ... Dozens of genes had multiple DMRs that were often seemingly positioned to regulate specific splice variants. Our results ... Most DMRs were inside genes supporting neural development, synapse function, and other processes relevant to neural plasticity ... causing fast behavioral modifications and a cascade of changes in gene transcription, the brain, and the reproductive system. ...
Targeted Agents Active Against Breast Cancer: Q&A - NCI
HER2 is a member of the epidermal growth factor receptor (ErbB) family of genes, which encode proteins that are cell surface- ... The researchers also examined the PTEN tumor suppressor gene (because cancers that have lost this gene are thought to respond ... HER2-positive (HER2+) breast cancers are defined as those that have an excess number of HER2 genes or over-produce the protein ... Its effect on the function of other proteins in the ErbB family of proteins that may also fuel cancer cell growth is being ...
Oncogene - Texas A&M University (TAMU) Scholar
C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines. ... Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of ... MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.. 27:4373-4379. 2008 ... IKK-dependent, NF-B-independent control of autophagic gene expression.. 30:1727-1732. 2011 ...
Genistein - Wikipedia
Gene reporter assays showed that genistein at concentrations between 1 and 100 uM activated PPARs in a dose dependent way in ... "Genistein induces enhanced growth promotion in ER-positive/erbB-2-overexpressing breast cancers by ER-erbB-2 cross talk and p27 ... 86 (2): 318-23. doi:10.1093/toxsci/kfi200. PMID 15901918.. *^ a b Jin, Ying; Wu, Heng; Cohen, Eric M.; Wei, Jianning; Jin, Hong ... 278 (2): 962-7. doi:10.1074/jbc.M209483200. PMID 12421816.. *^ Dang, Zhi Chao; Lowik, Clemens (2005). "Dose-dependent effects ...