Animal-viruses-and-immunity|omicsgroup|journal Of Veterinary Science
In antigenic drift, viral genes mutate altering virus surface proteins. This results in the development of a new virus strain ... In antigenetic shift, a new virus subtype is produced through the combination of genes from different viral strains. ... Antigenetic shifts are associated with pandemics as host populations have no immunity to the new viral strain. Open Access ... Other viruses, such as influenza viruses, experience changes in their genes leading to antigenic drift or antigenic shift. ...https://www.omicsonline.org/animal-viruses-and-immunity-open-access-journals.php
Animal-viruses-and-immunity|omicsgroup|journal Of Veterinary Science
In antigenic drift, viral genes mutate altering virus surface proteins. This results in the development of a new virus strain ... In antigenetic shift, a new virus subtype is produced through the combination of genes from different viral strains. ... Antigenetic shifts are associated with pandemics as host populations have no immunity to the new viral strain. Open access ... Other viruses, such as influenza viruses, experience changes in their genes leading to antigenic drift or antigenic shift. ...https://www.omicsonline.org/animal-viruses-and-immunity-articles-open-access.php
A New Preparation Method for Ophthalmic Drug Nanoparticles | OMICS International
Retinal gene therapy. VMD2-eGFP, PEG-POD NPs, Compacted DNA NPs. Age-related macular degeneration. PEG-LPH-NP siRNA, PLA/PLA- ... Viral keratitis. SLNs, NLCs. Wounds of the corneal epithelium. All-trans retinoic acid NPs. ...https://www.omicsonline.org/open-access/a-new-preparation-method-for-ophthalmic-drug-nanoparticles-2153-2435.1000305.php?aid=30058
Evolutionary Perspective of Human Papilloma Virus Infection in Humans | OMICS International
The different genes regulated different functions from viral replication to the formation of the viral assembly [8-11]. E6 is ... controlling gene called P53 and E7 is associated with other Cancer protective gene called Rb gene or Retinoblastoma gene [8-11 ... The E region has mainly 7 genes and sometimes it is 8 in rare HPV stains [8-11]. The genes are E1, E2, E3, E4, E5, E6, E7 and ... Viral Load in the tissues, Telomerase activity and others must be studied through modern tools like Gene expression arrays. ...https://www.omicsonline.org/evolutionary-perspective-of-human-papilloma-virus-infection-in-humans-jaa.1000070.php?aid=17405
The Pro-viral Role Of Autophagy In Coxsackievirus-induced Myocarditis | 2270
Blockage of autophagosome-lysosome fusion by gene silencing of the lysosomal protein LAMP2 promotes viral replication. These ... Cleavage of p62 may be a viral strategy to establish efficient viral replication in host cells. Biography. Dr. Honglin Luo is ... The pro-viral role of autophagy in coxsackievirus-induced myocarditis. Honglin Luo and Junyan Shi ... To further explore the pro-viral mechanisms of autophagy, we examined the protein levels of p62. P62 is an adaptor protein ...https://www.omicsonline.org/proceedings/the-proviral-role-of-autophagy-in-coxsackievirusinduced-myocarditis-2270.html
Effect of Intra-Medullar and Intra-Venous Infusions of Mesenchymal Stem Cells on Cell Engraftment by <em>In-Vivo</em> Cell...
The MSC were cultured, transduced by foamy viral vectors with marker genes for in vivo cell tracking, and expanded. All rabbits ... transduced by foamy viral vectors with marker genes (NOoA/ NOoB) at 2 moi (multiplicity-of-infection) at day -30 to -60, and ... transduced by Foamy viral (FV) vector carrying 2 marker genes (NOoA or NOoB), as illustrated. C: The ectopic bone formation was ... recombinant foamy viral vectors with the marker genes were produced by calcium phosphate transfection of 293T cells with four ...https://www.omicsonline.org/open-access/effect-of-intramedullar-and-intravenous-infusions-of-mesenchymal-stem-cells-on-cell-engraftment-by-invivo-cell-tracking-2161-0533-3-1000172.php?aid=32660
Generally virology deals with the study of infectious agents such as Virulence, Viruses, Viral Taxonomy, Viral Cultures and ... They act as a media for transferring genes between different species. Viruses are classified into different types. ...https://www.omicsonline.org/conferences-list/general-virology
WASp and WAVE Proteins: From Structure, Through Function, to Clinical Aspects | Open Access Journals
Gene therapy. Previous studies show that gene therapy can offer an alternative treatment for patients who lack an appropriate ... Recently, WAVE2 was found to be involved in HIV-1 viral infection. HIV-1 enters the cells by fusion at the plasma membrane or ... Nuclear WASp was shown to engage Th1-specific genes, but not Th2 or T regulatory (Treg) genes, in vivo under TH1- ... Gene Ther 10: 803-809.. *Strom TS, Turner SJ, Andreansky S, Liu H, Doherty PC, et al. (2003) Defects in T-cell-mediated ...https://www.omicsonline.org/wasp-and-wave-proteins-from-structure-through-function-to-clinical-aspects-2155-9899.S12-001.php?aid=8246
To Restrict the Growth of Cancer and Convert it into a Cancer without Disease or Remission by Changing Dietary Patterns | OMICS...
A gene that codes for Kirsten rat sarcoma viral oncogene homolog in Humans; MCHC: Mean Corpuscular Haemoglobin Concentration; ... A gene found in Rous sarcoma virus that encodes a tyrosine kinase; VUJ: Vesico Ureteric Junction; WBC: White Blood Cells; ... B dependent genes COX-2 and AIF-1 in certain tumor and also reduced certain inflammatory markers like macrophage inflammatory ...https://www.omicsonline.org/open-access/to-restrict-the-growth-of-cancer-and-convert-it-into-a-cancer-1948-5956.1000320.php?aid=39072
Maria ISAGULIANTS | Karolinska Institutet, Sweden, and Riga Stradins University, Latvia. | Vaccines-2014
Strong immune response against viral antigens responsible for drug resistance can create a bottle-neck to viral evolution ... Optimal multi-gene combinations and routes of plasmid administration were identified. Safety tests are on-going. The key issue ... Immune response against HIV enzymes can be induced by a cocktail of their genes shaped into DNA-vaccines. We pioneered the use ... Maria is working on the design and preclinical testing of prototype vaccines against chronic viral infections including HIV-1 ...https://www.omicsonline.org/speaker/Maria_ISAGULIANTS_Karolinska_Institutet_Sweden_And_Riga_Stradins_University_Latvia_Vaccines2014/
DNA Vaccines: How Much Have We Accomplished In The Last 25 Years? | OMICS International
The inclusion of a strong viral-derived promoter/enhancer has provided superior gene expression in vivo than other eukaryotic ... 1993) Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum Gene ... Lungwitz U, Breunig M, Blunk T, Göpferich A (2005) Polyethylenimine-based non-viral gene delivery systems. Eur J Pharm Biopharm ... Gene Ther 1: 114-121.. *Vitadello M, Schiaffino MV, Picard A, Scarpa M, Schiaffino S (1994) Gene transfer in regenerating ...https://www.omicsonline.org/open-access/dna-vaccines-how-much-have-we-accomplished-in-the-last-25-years-2157-7560-1000283.php?aid=55732
Surface Plasmon Resonance Based Recent Advances in Understanding Plant Development and Related Processes | OMICS International
Xie DX, Feys BF, James S, Nieto-Rostro M, Turner JG (1998) COI1: An Arabidopsis gene required for jasmonate-regulated defense ... Real time binding kinetic studies of viral proteins (VirE1 and VirE2) and ssDNA using SPR have shown that their binding is ... Moyroud E, Reymond MC, Hamès C, Parcy F, Scutt CP (2009) The analysis of entire gene promoters by surface plasmon resonance. ... Real time binding kinetic analysis of viral proteins (VirE1 and VirE2) and ssDNA using SPR has shown that binding is strongly ...https://www.omicsonline.org/open-access/surface-plasmon-resonance-based-recent-advances-in-understandingplant-development-and-related-processes-2161-1009-1000300.php?aid=84432
Supramolecular Facilities to Melanoma Cells B16F10 with Nanoparticles of a DEAE-Dextran-MMA Copolymer-Paclitaxel Complex |...
2009) Mechanism of introducing exogenous genes into cultured cells using DEAE-dextran- MMA graft copolymer as non-viral gene ... mechanism of the introduction of exogenous genes into cultured cells using DEAE-dextran-MMA graft copolymer as a non-viral gene ... dextran-mma graft copolymer for non-viral gene delivery. J Gene Med 10: 472. ... In such studies, gene expression was measured for 24 hours after treatment, which showed that gene clustering over time in ...https://www.omicsonline.org/supramolecular-facilities-to-melanoma-cells-b16f10-with-nanoparticles-of-a-deae-dextran-mma-copolymer-paclitaxel-complex-2157-7439.S5-002.php?aid=6726
A Toll-Like Receptor 3-Agonist as Promising Candidate in Multiple Sclerosis Treatment | OMICS International
Marié I, Durbin JE, Levy DE (1998) Differential viral induction of distinct interferon-alpha genes by positive feedback through ... RNase L plays a protective role in CNS demyelination viral-induced, since it is capable of both inhibiting the viral genome ... The genes induced by TLR3 activation include IFNs, 2-5' adenylate synthetase, and protein kinase (p68) [73,74]. As reported by ... Lafon M, Megret F, Lafage M, Prehaud C (2006) The innate immune facet of brain: human neurons express TLR-3 and sense viral ...https://www.omicsonline.org/open-access/a-tolllike-receptor-3agonist-as-promising-candidate-in-multiple-sclerosis-treatment-2155-9899-1000339.php?aid=59057
Diagnostics and Treatment of Metastatic Cancers with Magnetic Nanoparticles | OMICS International
Gene delivery by viral vectors can be highly efficient (80-90%) but may insert viral vector nucleic acid sequences into the ... There are two types of gene therapy: somatic gene therapy and germ line gene therapy. In somatic gene therapy, the therapeutic ... Magnetic gene therapy. Gene therapy is an experimental technique that uses genes to treat or prevent diseases. The most common ... This are inherited and passed on to later generation . There are three primary gene delivery systems that employ viral ...https://www.omicsonline.org/diagnostics-and-treatment-of-metastatic-cancers-with-magnetic-nanoparticles-2155-983X.1000115.php?aid=17991
De Novo Design of Antiviral and Antibacterial Peptides with Varying Loop Structures | OMICS International
Antimicrobial peptides melittin and cecropin inhibit replication of human immunodeficiency virus 1 by suppressing viral gene ... Beard JA, Bearden A, Striker R (2011) Vitamin D and the anti-viral state. J Clin Virol 50: 194-200. ... They proposed that cycloviolacin Y5 acted on viral membranes. Whether GLRC-2 acts by the same mechanism remains to be ... our studies may also contribute to the identification of novel antimicrobial agents with activity against other viral and ...https://www.omicsonline.org/de-novo-design-of-antiviral-and-antibacterial-peptides-with-varying-loop-structures-2155-6113.S2-003.php?aid=2870
Clinical Complications of Type-2 Diabetes Mellitus in South Asian and Chinese Populations: An Overview | OMICS International
Gene Ther 14: 162-172.. *Kay MA, Glorioso JC, Naldini L (2001) Viral vectors for gene therapy: the art of turning infectious ... Gene therapy is a method to replace mutated or diseased gene with a normal gene. Gene therapy based treatment provides long- ... Numerous non-viral gene delivery methods are under development for Glucagon-Like Peptide (GLP1) gene delivery. Oh et al.  ... Viral vectors are currently the best choice for gene transfer. There are various virus vectors that are being used for human ...https://www.omicsonline.org/open-access/clinical-complications-of-type-diabetes-mellitus-in-south-asian-and-chinese-populations-an-overview-2155-6156.1000420.php?aid=30673
Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection
Here, we focus on the effect of negative frequency-dependent selection (NFDS) such as caused by viral predation (kill-the- ... Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection. Most microbes in ... winner dynamics). The NFDS maintains multiple genotypes within a population, so that a gene beneficial to every individual ... would have to spread via recombination, hence a gene-specific selective sweep. ...https://www.omicsonline.org/blog/2015/05/12/11849-Genespecific-selective-sweeps-in-bacteria-and-archaea-caused-by-negative-frequencydependent-selection.html
Comparison of the Immunity Status in-Between Children with Î²-Thalassaemia Major Receiving Different Treatment Modalities: A...
Recently, gene therapy and bone marrow transplant or stem cell therapy are promising hopes . Volumetric and multiple ... Accordingly, this raises the concern of reduced resistance to viral infections and to the development of malignancy . This ... Thalassaemia is defined as a group of inherited disorders that arise as a result of certain mutations in hemoglobin (Hb) genes ... About 1.5% of the world populations are carriers of β-thalassaemia gene . βTM patients present with many problems rather ...https://www.omicsonline.org/open-access/identification-of-the-immunological-profile-in-some-egyptian-children-with-thalassaemia-major-under-different-treatment-modalities-1745-7580-10000127.php?aid=86449
Aboul-Ata Elnady Aboul-Ata | Professor and Phytovirologist Plant Virus and Phytoplasma Research Agricultural Research Center ...
Aboul-Ata is the author of more than 40 scientific papers in different approaches i.e. gene silencing, sequencing of viral ... genes. He is being the author of Chapters in different books i.e. Mediterranean Link Committee for Processing Tomato Research ( ...https://www.omicsonline.org/committee/AboulAta_Elnady_AboulAta__Clinical_Microbiology2014/